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At least 163 records · Page 9Linked to original sources
PubMed2004

Trickle-bed root culture bioreactor design and scale-up: growth, fluid-dynamics, and oxygen mass transfer.

Trickle-bed root culture reactors are shown to achieve tissue concentrations as high as 36 g DW/L (752 g FW/L) at a scale of 14 L. Root growth rate in a 1.6-L reactor configuration with improved operational conditions is shown to be indistinguishable from the laboratory-scale benchmark, the shaker flask (mu=0.33 day(-1)). These results demonstrate that trickle-bed reactor systems can sustain tissue concentrations, growth rates and volumetric biomass productivities substantially higher than other reported bioreactor configurations. Mass transfer and fluid dynamics are characterized in trickle-bed root reactors to identify appropriate operating conditions and scale-up criteria. Root tissue respiration goes through a minimum with increasing liquid flow, which is qualitatively consistent with traditional trickle-bed performance. However, liquid hold-up is much higher than traditional trickle-beds and alternative correlations based on liquid hold-up per unit tissue mass are required to account for large changes in biomass volume fraction. Bioreactor characterization is sufficient to carry out preliminary design calculations that indicate scale-up feasibility to at least 10,000 liters.

Biomass↗
PubMed2006

Some Lithuanian ethnobotanical taxa: a linguistic view on thorn apple and related plants.

BACKGROUND: The perception and use of plants correspond with common plant names. The study of plant names may give insight into historical and recent use of plants. METHODS: Plant names in dictionaries and folklore have been evaluated. A etymological analysis of the names is provided. Onomasiological and semasiological aspects have been considered. Therefore, species named with names related to each other have been selected. RESULTS: Plant names containing the stem dag- or deg- may belong to either of two categories: incenses or thorny plants. Plants named in durn- have been in use as psychopharmaca. The name rymo points not to Rome but to the use of plants as anodyne or psychopharmaca.

Atropa belladonna↗
PubMedDate not supplied

Effects of an anthroposophical remedy on cardiorespiratory regulation.

CONTEXT: The human organism has the inherent ability to regulate and coordinate physiological functions to establish well-being. If this ability is disturbed, eg, in cases of orthostatic syndrome with purely functional disorders, an herbal remedy based on anthroposophical medicine may be able to regulate such rhythmic disturbances. OBJECTIVE: To determine the effect of the anthroposophical herbal remedy on stimulating the ability to regulate and coordinate physiological functions in healthy subjects. DESIGN: Double-blind, placebo-controlled, randomized trial PARTICIPANTS: Ninety-nine healthy subjects; 49 received the remedy, 50 received the placebo. INTERVENTION: Oral administration of the remedy for 4 weeks, 20 drops 4 times daily. MAIN OUTCOME MEASURES: Cardiorespiratory interaction was analyzed by 2 measures: the heart-respiratory ratio and the phase-coordination ratio of heartbeat and respiration. They were calculated from heart rate and respiratory rate, which were derived from 24-hour electrocardiogram recordings before and after the administration of the remedy. Improved normalization of these measures during nighttime sleep after administration of the remedy indicates a stimulation of regulation. RESULTS: Oral administration of the remedy resulted in an improved normalization of heart-respiratory ratio, phase-coordination ratio and heart rate during nighttime sleep. These results were not observed in the placebo group. CONCLUSIONS: The remedy stimulates the regulation of cardiorespiratory interaction during nighttime sleep. Furthermore, improved normalization indicates a general improvement of the regulatory processes of functional rhythms.

Adult↗