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Evaluation of mandibular reconstruction techniques following resection of malignant tumors in the oral region.

Over the past 15 years, reconstruction following excision of malignant oral tumors was performed on 27 patients with segmental resection and five patients with hemiresection of the mandible. Following segmental resection, the mandible was reconstructed using an autogenous bone graft in eight patients in whom the surrounding soft tissues were fairly well preserved. Bony union was achieved in six of them. In the remaining two, the graft was removed because of postoperative infection, and one patient underwent secondary bone grafting. A pedicled myocutaneous flap and bone graft was used in seven patients who underwent extensive resection of the surrounding soft tissue. Bony union was achieved in three patients, and one developed pseudoarthrosis. The graft was removed in the remaining three because of postoperative infection. Reconstruction with only a metallic plate for stabilization of the mandible was carried out in six aged or sarcoma-affected patients. In two of them, the postoperative course was uneventful for 4 to 7 years. In the remaining four patients, plate removal was required because of exposure or tumor recurrence. In 5 of 11 patients in whom reconstruction was carried out with a combination of a pedicled myocutaneous flap and metallic plate, the postoperative course was uneventful for 2 to 8 years. Two of these five patients underwent secondary bone grafting. In four of the remaining six patients, the plate was removed because of exposure or improper adaptation to the stump. Two others died of disseminated intravascular coagulation syndrome within 1 month. A prosthesis was used more frequently by patients when reconstruction was performed using a pedicled osteomyocutaneous flap. The metallic reconstruction plate was helpful for restoring mandibular contour.(ABSTRACT TRUNCATED AT 250 WORDS)

Adenocarcinoma↗

Mandibular reconstruction with the Dacron urethane tray: a radiologic assessment of bone remodeling.

A retrospective study was made of 22 consecutive patients who underwent mandibular reconstruction with a Dacron (Osteo-mesh, Xomed Inc, Jacksonville, FL) tray technique from September 1988 to April 1992. Free autogenous iliac bone, in the form of particulate cancellous chips and marrow, was densely packed into the Dacron tray, that was adapted to bridge the mandibular segmental defect. Sixteen cases underwent uneventful healing with the formation of a continuous bony bridge and union with the remaining mandible. The pattern of bone remodeling and rate of resorption in these cases were assessed by sequential panoramic radiographs taken up to 3 years postoperatively. The mean horizontal dimension of the mandibular defects was 75 mm and the mean vertical reconstructed height was 25 mm. When the grafted bone was radiographically of uniform density, it progressed into a mature trabecular pattern matching that of the normal mandible. However, when there were areas of radiolucency, most likely from inadequate condensation of the graft, such areas were not replaced by bone in the long term. The bony height at both ends and the middle of the reconstructed segment underwent reasonably even resorption and retained about 80% of the bony height over a 3-year period. The rate of resorption was highest in the first 6 months and stabilized at about 2 years. There were six failures, all showing significant irregular bony resorption prior to tray removal.

Adolescent↗

Reconstruction of large defects postmandibulectomy for oral cancer using plates and myocutaneous flaps: a long-term follow-up.

A series of 28 consecutive cases of mandibular reconstruction by means of reconstructive plates and myocutaneous flaps were reviewed. In all cases mandibular resection was indicated for treatment of squamous cell carcinoma of the oral cavity: 25 pelviglossomandibulectomies (resulting in large defects from the angle of the mandible), 2 Commando operations (resulting in lateral defects) and 1 anterior sectional mandibulectomy (resulting in an anterior defect). Tumour stages were T1-T2 (4 cases) and T3-T4 (24 cases). Success was defined as plate maintenance 6 months' postoperatively/postradiotherapy. The overall success rate was 32.2%. Lateral-centre-lateral (L-C-L) defects had 32% success, L (lateral) defects had 50% success and in the single case of a C (centre) defect, the plate was not maintained. Stainless steel reconstruction plates showed a similar success rate as titanium plates (30% versus 34%). In cases not submitted to radiotherapy there were more maintained plates than in cases that received radiotherapy (45.5% versus 23.6%). Reconstruction plates are not effective in bridging large defects of the resected mandible. Only in selected cases that are not eligible for microvascular free flaps should plates and myocutaneous flaps be considered as an option for mandibular reconstruction.

Adolescent↗

Reconstruction of the mandible after ablative surgery for the treatment of aggressive, benign odontogenic tumours in Tanzania: a preliminary study.

This study presents results on 11 patients suffering from ameloblastoma who had ablative surgery followed by reconstruction of the mandible in a single operative procedure in Tanzania. The procedure included the use of autogenous particulate bone from the anterior or posterior iliac crest. In 6 of the patients, the tumour was removed from the cortical scaffold, which was then irradiated with 50 Gy. Perforations were made on the scaffold and it was then placed back to fit the defect and was held in place by custom-made titanium plates, fixed on both ends with screws. The particulate bone chips were mixed with autogenous platelet rich plasma (PRP) and Tissue Col. In 5 of the patients, the cortical scaffold was not used but rather a mixture of bone and PRP was packed into the defect under the titanium plates. Four patients had some complications varying from fracture of the scaffolds to infection. None from the group reconstructed without scaffolds suffered any complications. A quality of life (QOL) assessment of the 7 successful cases showed that these patients were satisfied and had a good QOL. These results imply that this immediate means of reconstruction is feasible and thus, offers a big advantage to the patients.

Adolescent↗

Efficacy of narrow-margin excision of well-demarcated primary facial basal cell carcinomas.

BACKGROUND: A 4-mm surgical margin of clinically normal skin is the current standard for elliptical excision of basal cell carcinomas (BCCs). However, a 4-mm surgical margin is often not feasible on the face because of cosmetic and functional concerns. As such, facial excisions of BCCs are typically performed with the appropriate margin determined by the surgeon based on clinical features of the tumor. OBJECTIVE: We designed a study to test the efficacy of narrow-margin elliptical excisions for the treatment of small, well-demarcated facial BCCs. METHODS: A total of 134 primary, small (<1 cm), well-demarcated, facial nodular BCCs were excised as an ellipse with 1-, 2-, or 3-mm margins around the visible border of the tumor. The margin used was decided by the dermatologic surgeon based on cosmetic, anatomic, and functional factors, with the goal of clearing the tumor in a single excision. Using the Mohs technique for elliptical specimens, frozen sections were prepared and examined microscopically to provide complete histologic margin control. RESULTS: In all, 134 facial BCCs were included in the study. On average, the tumors measured 0.6 x 0.5 cm. Of these, 27 (20.1%) had positive margins, requiring additional excision. Excisions with 1-, 2-, and 3-mm margins were associated with positive margins in 16%, 24%, and 13% of tumors, respectively. There was no statistically significant difference in the occurrence of positive margins based on tumor size, anatomic location, or the measured margin used. CONCLUSION: Narrow margins (1-3 mm) are inadequate for the excision of small, well-demarcated, primary nodular BCCs of the face. To avoid repetitive operations and the risk of recurrence in anatomically sensitive areas, these tumors should be treated with standard wide margins (eg, 4 mm), or have Mohs micrographic surgery for histologic margin control.

Basal Cell Carcinoma↗

Mandibular reconstruction using the titanium functionally dynamic bridging plate system: A retrospective study of 34 cases.

PURPOSE: We sought to examine the use of the Titanium Functionally Dynamic Bridging Plate System (Howmedica Leibinger, Freiburg, Germany) for mandibular reconstruction after oncologic resection in 34 patients. PATIENTS AND METHODS: A retrospective study of 34 patients who had mandibular reconstruction using the titanium dynamic bridging plate system for mandibular reconstruction after oncologic resection were evaluated. The indications and postoperative outcomes were studied. Our evaluation focuses on the tolerance and aesthetic and functional results of this system. RESULTS: The follow-up ranged from 1 to 4 years. At the end of the study, 18 of the 34 patients (53%) still had the plate in place. One plate fracture and 1 plate exposure requiring surgical management were found. Surgical results were satisfying, particularly when looking at healing delay or long-term tolerance. Aesthetic (79% rated the results as good or acceptable) and functional results of this reconstruction material were satisfying. CONCLUSION: This reconstruction system provides a solution for a safe and rapid mandibular reconstruction for patients with a poor prognosis or poor general condition. This method also preserves the possibility of secondary reconstruction.

Adult↗

Minimizing complications in the use of titanium condylar head reconstruction prostheses.

OBJECTIVE: The study goals were to evaluate the use of titanium condylar prostheses in the setting of tumor resection and to discuss the techniques used to minimize complications. STUDY DESIGN AND SETTING: We conducted a retrospective review of a case series in a tertiary care hospital. Six patients underwent mandibulectomy, including the condyle, with primary reconstruction using titanium condylar prostheses. Charts were reviewed for operative technique, pathology, and complications. RESULTS: Pathology included squamous cell carcinoma, Ewing's sarcoma, embryonic rhabdomyosarcoma, giant cell granuloma, and adenocarcinoma. Three patients are alive without disease. Follow-up spanned 6.4 years with premorbid occlusion established in all cases, and there were no prosthesis extrusions or erosions. The condylar head was wrapped in preserved joint capsule or adjacent temporalis muscle/fascia and secured with permanent purse-string sutures; careful duplication of the length, and angulation of the native mandible from the angle to the superior extent of the condylar head. CONCLUSION: Titanium condylar prostheses are a viable choice in the setting of tumor resection and reconstruction, with appropriate technical precautions.

Adult↗

Reconstruction of lateral mandibular defects with dynamic bridging plates.

The principle of mandibular reconstruction by dynamic bridging plates in association with a bone graft is based on the double bridge reconstruction method. However, the plate can be used alone. Our aim was to report the long-term results of this treatment for mandibular lateral defects in fragile patients. From 1993 to 1999, 38 consecutive patients had primary reconstructions with bridging plate for lateral mandibular defects. Their mean age was 58.4 years (26-86) and the mean follow-up was 50 months (6-89). Excluding removal of plates for local recurrences, the overall success rate was 78%. Plates were removed after a mean of 20.4 months (1-66). No plates fractured. Dynamic bridging plates allow an immediate and efficient reconstruction with reduced operating time and compare favourably with conventional plates. They can also be used as a stand-by for patients who are to have a delayed free flap reconstruction.

Adult↗