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How to write an experimental research paper.

The art and practice of academic neurosurgery are mastered by defining and learning the pertinent basic principles and skills. This article aims to present general guidelines to one of the many roles of a neurosurgeon: Writing an experimental research paper. Every research report must use the "IMRAD formula: introduction, methods, results and discussion". After the IMRAD is finished, abstract should be written and the title should be "created". Your abstract should answer these questions: "Why did you start?, what did you do?, what answer did you get?, and what does it mean?". Title of the research paper should be short enough to catch glance and memory of the reader and be long enough to give the essential information of what the paper is about. Writing about the results of the experiment is no easier than the research itself. As surgery, writing a scientific paper is also an improvisation, but general principles should be learned and used in practice. The most effective style of learning basic skills to construct a research paper is the "trial and error" type.

Curriculum↗

Information synthesis: a practical guide.

Information synthesis is one of the most valuable contributions a scientist can make. This paper offers guidance in preparing information synthesis and a means of assessing their adequacy. Preparing an information synthesis requires four steps: defining the topic and relevant information about that topic, the purpose of the synthesis, and the target audience; systematically gathering this relevant information; assessing the validity of such information; and presenting validated information in a way useful to the target audience. This paper presents guidelines and criteria for each step, and some helpful hints for authors in preparing an information synthesis.

Documentation↗

[The most frequently cited articles in the SCI and SSCI of the Zeitschrift fur Psychosomatische Medizin und Psychotherapie (Journal of Psychosomatic Medicine and Psychotherapy) -- a review and analysis].

AIM: We investigate which articles out of the entire fifty volumes of the Zeitschrift fur Psychosomatische Medizin und Psychotherapie (Journal of Psychosomatic Medicine and Psychotherapy (Psychoanalysis) have been most frequently cited. These articles are analysed according to the groups of authors and topics. METHODS: The citation frequency was determined in the source journals listed by the ISI and contained in the SCI and SSCI data banks. RESULTS: 58 articles were cited at least ten times, and five of these articles were cited at least twenty times. One article was cited 45 times and thus was the top runner. The authors who are particularly important in their specialized areas dominated, and the most frequently cited articles were distributed quite evenly in both psychosomatic and psychotherapeutic topics. DISCUSSIONS: A relatively large number of articles in this journal have a sustained influence among experts in the field. Since there are not many of German journal listed in the ISI data banks or have only recently been included by them, the number of citations is most likely considerably higher.

Authorship↗

[Intensive care medicine -- update 2004].

This manuscript gives a review about important studies addressing problems in intensive care medicine that have been published in journals focussing on critical care medicine and surgery in 2004. Only clinical studies are included in this review, mostly metaanalyses, randomized controlled trials and a few important or interesting observational studies. In addition to describing major results a critical appraisal of each study is undertaken, which, however, is neither comprehensive nor complete. It is merely intentioned to address some important aspects for the reader that should be accounted for while interpreting the results. It is important to note that among the large number of excellent studies there is a substantial proportion of trials with negative results that significantly add to our knowledge. Some of the topics addressed in this manuscript include vasopressin as an alternative to epinephrine during cardiopulmonary resuscitation, a specification concerning the use of activated protein C in patients with sepsis, the role of steroids in the treatment of sepsis and traumatic brain injury, the epidemiology of ALI and ARDS, the role of sedation protocols, weaning protocols and the timing of tracheostomy for the duration of mechanical ventilation, the potential benefit of catheters with antimicrobial coating to reduce catheter-related sepsis, and the benefit of enteral nutrition as compared to the parenteral application.

Critical Care↗

Earliest historic reference of 'tinnitus' is controversial.

Tinnitus, that is defined as 'ringing in the ear', is and has probably always been a very common phenomenon in the health history of mankind. A variety of pathomechanisms for its onset has been proposed in the past and this trend sees no stopping. Precise pathomechanisms still remain unclear. From the historical point of view, tinnitus is a very interesting topic but there is a lack of scientific enquiries. As its earliest historic reference, the Papyrus Ebers is often cited. By reviewing the original source, however, it is very unlikely that this contains the earliest historic reference of tinnitus. It is rather likely indeed that tinnitus was a known symptom in the ancient Egypt but it has never been exclusively been written down. This article reviews data provided by this fascinating historical period on the questionable reference and highlights the impact of history on the modern status of tinnitus.

Egypt, Ancient↗

A literature assessment of the use of miscellaneous topical agents, growth factors, and skin equivalents for the treatment of pressure ulcers.

BACKGROUND: Agents reviewed for this manuscript were both rare and popular topical treatments for pressure ulcers. OBJECTIVE: To review topical treatments for pressure ulcers and evaluate them based on available literature of controlled, blinded, and randomized trials. METHODS: A MEDLARS database (1966-1993) search and a thorough review of reference article lists of key articles produced over 100 manuscripts. Studies were considered for review if they were conducted on humans with chronic stage II to IV pressure ulcers, in a properly controlled and randomized fashion. RESULTS: The use of zinc acetate and aluminum hydroxide ointment, phenytoin, recombinant platelet-derived growth factor-BB (rPDGF-BB), and basic fibroblast growth factor (bFGF) have been evaluated in a controlled and blinded fashion. Many of the newer agents, cytokine growth factor (eg, rPDGF-BB and bFGF) and skin equivalents, are currently being scrutinized in clinical trials. CONCLUSION: A paucity of data exist that adequately address the efficacy of any topical agent for the treatment of pressure ulcers.

Administration, Topical↗