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Results for “NEOPLASMS, MULTIPLE PRIMARY”

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At least 163 records · Page 9Linked to original sources
PubMed1986

[Association of cancer of the thyroid gland with other malignant tumors].

In a group of 705 cases of thyroid cancer, 30 female patients (4.2%) had malignant tumors of other sites. Primary multiple neoplasms were registered in 5.8% of female cases. Combinations of thyroid cancer with breast or reproductive organs tumors were observed most frequently: 46.6 and 30%, respectively. In 10%, a second tumor was attributed to irradiation for primary malignancy. Three neoplasms were detected in 4 cases and four--in 1 patient. Cancer patients should be followed-up for evaluating treatment results and timely diagnosis of tumors of other sites.

Adolescent↗
PubMed1984

Multiple primary malignant neoplasms.

A 75-year-old man developed neurilemmoma of the left eighth cranial nerve, adenomatous polyp of the sigmoid colon, adenocarcinoma of the prostate, mixed cell type lymphoma of the right neck, and infiltrating ductal carcinoma of the right breast metachronously during a period of 38 years. The cancer of the right breast occurred 7 years after the long-term stilbestrol treatment of prostatic carcinoma, which suggests a causal relationship between the hormonal therapy and development of breast carcinoma.

Adenocarcinoma↗
PubMed2002

[Multiple primary malignant neoplasms].

OBJECTIVE: To investigate the epidemiological and clinical features of multiple primary malignant neoplasms (MPMNs). METHODS: One hundred and twenty-five cases of more than or equal to three primary malignant neoplasms detected in the period of 1958 to 2001 were studied retrospectively in terms of frequency, age of onset, sex ratio, tumor location and the interval between sequential tumors. RESULTS: The overall incidence of MPMNs was 0.090%; for three, four and five MPMNs was 0.078%, 0.009% and 0.001%. The mean age of onset of MPMNs was 64 years. The sex ratio, of male to female, was 1.0:1.2. The mean time interval was 7.1 years, and it reduced from 5.7 to 2.4 years in a descending order of the first, second, third, forth and fifth primary tumors. Three, four and five primary malignant neoplasms were predicated respectively in the large intestine, breast, lung, esophagus, uterus, skin; the large intestine, breast, skin stomach, urinary bladder, uterus; and the large intestine, breast, skin, parotid glands. CONCLUSIONS: The overall incidence of multiple primary malignant neoplasms seems to ascend. The age of onset of MPMNs tends to be increase. The incidence of in women is higher than in men. The time interval from the first to fifth primary tumor is decreasing. The susceptible organs are identical organ, bigeminal organs or organs of the same system.

Adult↗
PubMed1990

[Laryngeal cancer in multiple primary malignant neoplasms].

The analysis of the clinical material of patients with the multiple primary malignant neoplasms was performed. 963 patients were operated upon because of laryngeal cancer. In 39 (4%) there were also another primary malignant neoplasm, more frequent as the second lesion, more rare as the first before the laryngeal one. The late results of treatment were presented.

Adult↗
PubMed2001

[Rare case of multiple primary malignant neoplasm of the larynx: squamous carcinoma and fibrosarcoma].

The problem of primary mixed neoplasms has been recently a subject of numerous research works trying to find out their pathogenetic mechanisms, early detection, clinical course and treatment opportunities. The authors present a rare case (fibrosarcoma and squamous carcinoma) in a 73-year-old man. The patient had a surgery (total laryngectomy) and complementary irradiation at the Institute of Oncology.

Aged↗
PubMed1993

[Acute pneumonia in patients with multiple primary malignant neoplasms].

The authors review 35 cases of acute pneumonia (AP) in 30 patients with multifocal cancer. As a rule, AP was focal, ran a moderate or severe course, arose acutely with high temperature, chill, cough, purulent discharge. Auscultation registered weak vesicular breath, moist rale. Among pathological agents prevailed associations of pneumococci with gram-negative flora. AP resolved for 3-4 weeks in 2/3 of the patients, the rest of them developed lingering disease. From the point of view of antibacterial drugs efficacy, wide-spectrum drugs are preferable.

Acute Disease↗
PubMed1987

Multiple primary gynecologic neoplasms.

Some patients may be predisposed to the development of more than one gynecologic neoplasm. We evaluated 130 cases of synchronous or metachronous tumors among 5967 patients followed up by The Ohio State University Gynecologic Tumor Registry for the past 44 years from 1939 to 1983. Based on primary tumor site and invasive behavior, expected incidences for a specific second malignancy were calculated by the person-years method. A second malignancy of the lower genital tract occurred in patients with cervical, vulvar, and vaginal cancers, 1.6%, 4.3%, and 9.6%, respectively, which supports the theory of multicentric cancer of the lower genital tract. Prior radiation therapy was rarely associated with increased second gynecologic malignancies (two of 41 patients, 4.9%). Four patients had three gynecologic tumors.

Female↗