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Orgasmic frequency and plasma testosterone levels in normal human males.

Twenty males participated in a 2-month study examining the relationship between 8 a.m. plasma testosterone levels and orgasmic frequency. Within subjects, higher levels of testosterone are associated with periods of sexual activity. Over subjects, however, the direction of the relationship is reversed. Mean testosterone levels were higher for sexually less active individuals.

Adult↗

The sexual interaction of women with secondary orgasmic dysfunction and their partners.

This paper reports the sexual interaction of 48 couples in which the women had secondary orgasmic dysfunction and the men reported no difficulties in sexual functioning. The results were contrasted with a sample of 63 "sexually satisfied" couples. On the Sexual Interaction Inventory, male and female members of the dysfunctional couples reported greater dissatisfaction with the frequency and range of specific sexual activities engaged in than their counterparts in the normative sample. Males in the dysfunctional group rated their sexual pleasure slightly higher than the norm, whereas the dysfunctional females' ratings were below average on this dimension. Within the dysfunctional group, males reported low self-acceptance and mate acceptance, while the females were less accepting of themselves but more accepting of their mates' responsivity. The female members of the dysfunctional couples had an average knowledge of their partners' sexual preferences, whereas the males were less accurate than the normative group in their perceptions of their partners' sexual preferences. As expected, the dysfunctional group reported greater overall disharmony and dissatisfaction in their sexual interaction. Implications of these findings for future research are discussed.

Adult↗

Hypnotic susceptibility, inhibitory control, and orgasmic consistency.

Willingness to relinquish control, as evidenced by hypnotic susceptibility, enjoyment of alcohol, and inability to control thoughts and movements near the end of coitus, was found in this study to be predictive of the consistency with which females reported experiencing orgasm during sexual intercourse.

Adult↗

Orgasm consistency training in the treatment of women reporting hypoactive sexual desire: an outcome comparison of women-only groups and couples-only groups.

To evaluate and compare the effectiveness and maintenance of two group interventions using orgasm consistency training in the treatment of female hypoactive sexual desire, 57 women were randomly assigned to a women-only group, a couples-only group, or a waiting list control group. Controlling for social desirability, subjects were assessed on six variables: sexual compatibility, sexual esteem, sexual desire, sexual fantasy, sexual assertiveness, and sexual satisfaction. Independent assessments were made on these variables before treatment, after treatment, and at 6 months follow-up. Although the treatment was found to be generally effective in women reporting hypoactive sexual desire, a consistent pattern of change favoring the couples-only group was evident on all measures. Possible explanations for the superiority of couples-only interventions are explored in the discussion.

Adult↗

Increase in cerebral blood flow of right prefrontal cortex in man during orgasm.

The functional anatomy of human emotional responses has remained poorly understood, mainly because invasive experiments in humans are unacceptable due to ethical reasons. The new functional imaging techniques such as positron emission tomography and single photon emission computed tomography have made it possible to study the neurophysiology of living humans noninvasively. We studied the regional cerebral blood flow with semi-quantitative 99mTc-HMPAO single photon emission computed tomography in eight healthy right-handed heterosexual males during organism. The results showed decrease of cerebral blood flow during orgasm in all other cortical areas except in right prefrontal cortex, where the cerebral blood flow increased significantly (P < 0.005).

Adult↗

Tooth-brushing epilepsy with ictal orgasms.

We report a 41-year-old woman with complex reflex epilepsy in which seizures were induced exclusively by the act of tooth brushing. All the attacks occurred with a specific sensation of sexual arousal and orgasm-like euphoria that were followed by a period of impairment of consciousness. Ictal EEG demonstrated two events of epileptic seizure that were provoked after tooth brushing for 38 and 14 seconds, respectively. The interictal EEG showed epileptiform discharges over the right anterior temporal region and interictal single photon emission computed tomography (SPECT) scan showed relative hypoperfusion in the uncus of right temporal lobe. Brain magnetic resonance imaging (MRI) revealed right hippocampal atrophy. We suggest that tooth-brushing epilepsy, especially with sexual ictal manifestations, may provide insight into the cerebral pathophysiology at the right temporolimbic structure.

Adult↗

Nocturnal orgasm in college women: its relation to dreams and anxiety associated with sexual factors.

Ss (N = 774 female undergraduates) were administered a structured questionnaire and an anxiety scale. It was found that women do experience nocturnal orgasms during sleep. Chi-square analysis revealed that a differential exists between academic levels with senior experiencing states of sexual excitement more than freshmen, sophomores, and juniors. Sexual excitement during sleeping hours and a high degree of anxiety were positively related.

Adult↗

Primary orgasmic dysfunction: essential treatment components.

In an attempt to determine the essential components of a successful treatment regime for primary orgasmic dysfunction, the principle treatment approaches are reviewed to elucidate the similarities in different programs which have reported similar outcome data. It is concluded that the systematic desensitization studies, the masturbatory training approaches, and the Reproductive Biology Research Foundation series are all effective treatment procedures. It appears that all three approaches employ graduated exposure to sexual stimuli plus some form of directive psychotherapy emphasizing interpersonal skills acquisition. These may be the essential treatment components.

Female↗

Group treatment of situationally orgasmic women.

It appears that an all women's group treatment program is successful for two-thirds of the women who enter the program in terms of teaching them to experience orgasm with their partner more frequently and in different ways and that these changes are maintained. The program is most effective for those women in casual relationships and relationships which are of a committed or very serious nature but which have not been in existence for over 1 1/2 years. In those relationships that are committed, but over 3 years' duration, results are more mixed. It may be possible that additional conjoint treatment may increase the effectiveness of the program for these couples, but this hypothesis requires further research.

Adult↗

Changes in assertiveness and changes in orgasmic response occurring with sexual therapy for preorgasmic women.

Assertive behavioral effects of therapy for anorgasmia are examined. Four groups of preorgasmic women were measured on their assertive behavior before, after and four months following therapy focused on obtaining orgasm through self-stimulation. The results of measures of self-reported comfort with assertion as well as probability of acting assertively as measured by the Gambrill-Richey Assertion Inventory indicate that changes did occur in all groups. A significant decrease in felt discomfort with assertive behavior and an increase in the probability of responding assertively was found in all groups. Implications for considering the impact of sexual therapy on various aspects of interpersonal relationships rather than exclusively on symptom removal are suggested.

Adult↗

A comparison of three therapeutic formats in the treatment of secondary orgasmic dysfunction.

The goal of the present study was to compare the effectiveness of three therapeutic formats: Standard Couple Therapy, Group Therapy, and Minimal Contact Bibliotherapy (self-help) in the treatment of 23 couples in which the wife was suffering from secondary orgasmic dysfunction. The results indicate that a cognitive-behavioral sex therapy program is clearly effective in changing a wide range of subjective satisfaction and behavioral measures, with concurrence of the husbands' and wives' data providing further strength to these findings. Differences in outcome which were elicited in the three experimental treatment conditions were mainly in favor of the Standard Couple condition. Since such differences were neither frequent nor great, practical issues related to increasing the effectiveness of less time-consuming treatment formats are discussed. In addition, the theoretical implications of using global versus specific therapy outcome criteria are explored.

Adult↗

Measurement of therapy outcome and maintenance of gains in the behavioral treatment of secondary orgasmic dysfunction.

Choice of therapeutic goals and criteria used for evaluation of therapeutic outcome represent fundamental conceptual and methodological issues. The present investigation examined the relationship between how data were obtained (by retrospective questionnaire or ongoing daily self-monitoring), what outcome criteria were used (behavioral or cognitive-affective), whose data were being analyzed (the female or male partner), and when measurements were taken (at posttherapy or follow-up) in a sample of 23 couples with the problem of secondary orgasmic dysfunction in the wife. The results indicate that retrospective measurement was more optimistic than ongoing; cognitive-affective changes were twice as likely to occur as changes in behaviors; females benefited more than males; and there were considerable losses of therapeutic gains at follow-up. These results underscore the need for multiple measurement techniques and highlight the multidimensional quality of the sexual experience.

Adult↗

Psychiatric drugs and inhibited female orgasm.

The available evidence concerning sexual side effects of psychiatric drugs suggests that inhibited female orgasm may be associated with the use of hetereocyclic antidepressants, monoamine oxidase inhibitors, benzodiazepines, and neuroleptics. Possible mechanisms of action including anticholinergic, alpha adrenergic blockade, and serotonergic effects are discussed.

Antidepressive Agents↗

Antidepressant-induced orgasm disorder.

Most of the antidepressants approved for use in the United States, with the possible exceptions of bupropion and nefazodone, have been associated with drug-induced anorgasmia. Common strategies to overcome this drug side effect include waiting for tolerance to develop, dose reduction, change of dosing regimen, substitution of an alternative antidepressant, and coadministration of another drug. Current evidence suggests that antidepressant-induced anorgasmia may be mediated by 5HT2 antagonism of adrenergic mechanisms that underlie normal orgasm.

Antidepressive Agents↗

Vardenafil improved patient satisfaction with erectile hardness, orgasmic function and sexual experience in men with erectile dysfunction following nerve sparing radical prostatectomy.

PURPOSE: Nerve sparing radical retropubic prostatectomy (NS-RRP) results in erectile dysfunction in a significant number of patients. Vardenafil, a potent and selective phosphodiesterase type 5 inhibitor, is generally safe. It improves International Index of Erectile Function erectile function domain scores, and penetration and erection maintenance success rates in patients who have undergone NS-RRP. We report additional parameters important to patient perceptions regarding erection quality and satisfaction with sexual experience following NS-RRP. MATERIALS AND METHODS: A total of 440 men at 58 centers throughout the United States and Canada participated in this randomized, placebo controlled, double-blind trial with 3 phases, namely baseline (4-week untreated period), treatment (12 weeks) and followup (7 days). Participants received placebo (145), 10 mg vardenafil (146) or 20 mg vardenafil (149) at home on demand but no more than once per calendar day. Efficacy and satisfaction with erection quality and sexual experience were determined during the trial. RESULTS: The 10 and 20 mg vardenafil doses were significantly superior to placebo for the International Index of Erectile Function domains for intercourse satisfaction, orgasmic function and overall satisfaction with sexual experience (vs placebo p <0.0009). Significant improvement in the satisfaction rate with erection hardness were demonstrated for each vardenafil dose compared with placebo (p <0.0001). Vardenafil was generally well tolerated. Common adverse events were headache, vasodilatation and rhinitis. CONCLUSIONS: In this difficult to treat population of men with erectile dysfunction subsequent to NS-RRP on demand treatment with vardenafil during a 3-month period significantly improved key aspects of the sexual experience important to patient quality of life.

3',5'-Cyclic-GMP Phosphodiesterases↗

The effect on erection and orgasm of cystectomy, prostatectomy and vesiculectomy for cancer of the bladder: a clinical and electromyographic study.

Forty-three men who had been subjected to cystectomy and concomitant prostatectomy, vesiculectomy and urethrectomy were interviewed about their pre-operative and post-operative sexual activities at a mean of 3 (range 1 to 8) years after operation. Twenty-eight of the 38 men (74%) who had been sexually active continued to have some form of sexual activity, 21 of them achieving orgasm. Only 3 men had penile erection; 2 of them had been subjected to prostatectomy and 1 to prostatic resection. One of these men treated by prostatectomy had also had urethrectomy. Electromyographic registration from the striated external urethral sphincter, the bulbocavernosus muscle and the levator ani muscle showed normal duration of muscular contractions and length of interval between contractions after operation. The pattern of impulses during organs did not differ from that of normal men.

Adult↗

Fluoxetine and orgasmic sexual experiences.

The purpose of this article to describe a unique potential side effect of fluoxetine. A case report of a patient with post stroke depression treated with fluoxetine is presented. Fluoxetine was associated temporally with frequent short episodes of sexual excitement described by the patient as feeling like an orgasm. The relationship was dose dependent. Serotonergic medications, like fluoxetine, may induce sexual stimulation as a side effect. The mechanism for this effect is unclear but patients with organic brain disease may be at higher risk for this complication.

Aged↗

[Premature orgasm in the male].

To date, we have no uniform definition of ejaculatio praecox. In a qualitative approach, premature ejaculation is ascribed to a failure to control excitement. As causes, organic disorders and erectile dysfunction must be excluded. The majority of cases, however, are due to psychological or partnership problems. The history-taking should aim, in particular, to uncover possible anxiety in conjunction with premature orgasm, and also to establish the reactions of the partner. As therapy, medication (local anesthetics, antidepressive agents, PDE-5 inhibitors) and sexual-therapeutic measures are available. Since few sufferers take the initiative in seeking treatment, particular importance attaches to providing the public with information about the therapeutic options for treating this common disorder.

Anesthetics, Local↗