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At least 163 records · Page 9Linked to original sources
PubMed1998

Management and prevention of cardiovascular hemorrhage associated with mediastinitis.

OBJECTIVE: To elucidate the causes of cardiovascular hemorrhage associated with mediastinitis and to review recommendations for prevention and treatment. SUMMARY BACKGROUND DATA: Mediastinal debridement with immediate or early coverage using healthy, vascularized tissue has lead to greatly reduced morbidity and mortality for patients with mediastinitis. Myocardial hemorrhage has been anecdotally reported. PATIENTS AND METHODS: Over a 36-month period, 7 patients developed massive cardiovascular bleeding after undergoing debridement for poststernotomy mediastinitis. Causes included puncture or erosion by a sternal edge in three and tearing at the myocardial-sternal interface in four. RESULTS: Five patients survived and remain infection-free at an average of 24 months of follow-up. In these patients, ventricular defects were closed with pledgeted sutures and muscle transposition was used concomitantly to reinforce the repair. This involved a slide of the left pectoralis major muscle and turnover of the right pectoralis in three patients, bilateral sliding in one patient, and bilateral pectoralis and an omental flap in one patient who required additional coverage of the lower mediastinum. CONCLUSIONS: When a patient who has undergone mediastinal debridement shows evidence of significant bleeding, we recommend application of pressure for control of hemorrhage, expeditious return to an operating room with available cardiopulmonary bypass, and immediate muscle coverage with healthy, well-vascularized tissue. Finally, early sternectomy might largely prevent this life-threatening complication.

Aged↗
PubMed2006

A wire-cutting clamp designed to reduce complications during sternotomy closure.

PURPOSE: Sternal wire placement frequently results in glove disruption, wound contamination and personnel skin puncture. The described cutting clamp was developed to simplify sternotomy closure and reduce complications. DESCRIPTION: Informed consent was obtained from 103 patients who underwent a variety of common cardiac surgical procedures. In each instance, once the cardiac portion of the procedure was completed, the median sternotomy was closed using standard sternal wires and the described cutting clamps. A single set of clamps was repeatedly re-sterilized and used for all cases. EVALUATION: There were no incidents of unintentional clamp release, glove disruption or personnel skin punctures from the wire. None of the patients had clinically evident sternal wound infections or nonunion. There were no deaths. The functional attributes of the clamps remained constant throughout the study, and no significant wear was detected on the carbide inserts or other components of the clamps. CONCLUSIONS: The sternal wire-cutting clamp simplifies sternal closure and should reduce complications.

Bone Wires↗
PubMed2000

Cutaneous promyelocytic sarcoma at sites of vascular access and marrow aspiration. A characteristic localization of chloromas in acute promyelocytic leukemia?

Extramedullary disease (EMD) is a rare clinical event in acute promyelocytic leukemia (APL). Although the skin is involved in half of the reported EMD cases, the occurrence of cutaneous promyelocytic sarcoma (PS) has been described very rarely. We report here three cases of PS which have the peculiarity of appearing at sites of punctures for arterial and venous blood and marrow samples (sternal manubrium, antecubital fossa, wrist over the radial artery pulse, catheter insertion scar). At presentation, all patients had hyperleukocytosis and a morphologic diagnosis of microgranular acute promyelocytic leukemia variant confirmed at the genetic level by demonstration of the specific chromosomal translocation t(15;17). A BCR3 type PML/RARa transcript was documented in the two patients for whom diagnostic RT-PCR was available. Patients had morphologic bone marrow remission at the time the PS appeared. A predilection for the development of cutaneous PS at sites of previous vascular damage has been noted, but the pathogenesis remains largely unknown. A potential role for all-trans retinoic acid has been advocated, although one of the three patients in our series had received no ATRA. A review of the literature revealed six similar cases and hyperleukocytosis at diagnosis was a consistent finding in all of them. A careful physical examination of these particular sites in the follow-up of patients at risk, as well as cutaneous biopsy and laboratory examination of suspected lesions are strongly recommended.

Adolescent↗
PubMed1983

Accuracy of intracardiac injections determined by a post-mortem study.

Intracardiac injection sites were traced at necropsy on 18 patients who died after unsuccessful cardiopulmonary resuscitation. In only 13 patients (72%) was the heart punctured. Of the 46 injections carried out, 5 (11%) pierced the left ventricle and 13 (28%) the right ventricle. Other structures punctured included the pulmonary trunk, the aorta, and the lung. The fourth intercostal space just lateral to the sternal edge was the commonest injection site, and only 5 injections were subxiphoid. Post-mortem injections on a further 20 cadavers confirmed that the right ventricle is the most frequent puncture site whichever approach is used.

Autopsy↗
PubMed1995

[Retrograde percutaneous catheterization of the internal jugular vein in head injured patients].

The monitoring of jugular venous oxygen saturation and lactate concentration in order to detect cerebral ischaemia or hyperaemia requires the insertion of a fibreoptic catheter into the upper bulb of the internal jugular vein. With dissection studies we have defined superficial anatomical landmarks which are constant and easily palpable, namely the mastoid process and the sternocleidomastoid muscle. This technique does not require a rotation of the head. The puncture site is located at the top of a triangular area between its sternal and clavicular insertions. At this site the jugular vein is rather superficial. This study reports our experience of the retrograde catheterisation of the jugular vein in twelve severely head injured patients.

Adult↗
PubMed2004

Fatality following a sternal bone marrow aspiration procedure: a case report.

A 58-year-old man was admitted to hospital for the investigation and treatment of pancytopaenia and anaemic heart failure but four days later he died following a sternal bone marrow aspiration procedure. The autopsy revealed a significant haemopericardium as a result of a puncture wound of the heart. The thickness the body of the sternum was 2 to 3 mm. No other significant pathology was noted and death was ascribed to a haemopericardium due to a puncture wound of the heart associated with bone marrow aspiration. An inquest was held at which the doctor who undertook the procedure was found not to be negligent.

Adult↗
PubMed1980

Safe transthoracic left ventricular puncture performed with echocardiographic guidance.

Retrograde aortic left ventricular pressure recording is difficult to obtain and often unreliable in the presence of a mechanical aortic valve prosthesis. Under echocardiographic guidance, we have safely performed transthoracic left ventricular puncture for pressure recording in seven patients with an aortic valve prosthesis. The transducer is placed at the left sternal border and then slid laterally until the right ventricular cavity and interventricular septal echoes disappear, but before the echoes from the left lung are recorded. The chest wall is marked and the transducer is angled until the mitral valve echoes are identified. The transducer angle and direction are recorded with external markers, and the left ventricular cavity depth is measured. An 18-gauge needle is then inserted the determined depth into the left ventricle, guided exactly by the echocardiographic external markers. The procedure was successful in each patient on the first attempt without a single complication. We conclude that this technique affords the operator greater control when left ventricular pressure must be recorded by transthoracic puncture and that it may reduce the risk of potentially serious complications.

Aortic Valve↗
PubMed1988

Dynamic measurement of human capillary blood pressure.

1. Capillary blood pressure was measured in man using a dynamic servo-nulling system and direct micropuncture. This enabled assessments of the normal variations in pressure which influence fluid filtration and reabsorption. 2. Seventy-eight capillaries in 19 subjects were punctured in one of three positions around the capillary loop with the hand at the level of the sternal angle. Mean pressure around the loop fell from 37.7 +/- 3.7 mmHg (arteriolar limb, mean +/- SEM, n = 12) to 19.4 +/- 1.0 mmHg (apex, n = 25) to 14.6 +/- 0.5 mmHg (venular limb, n = 41) at skin temperatures of 18.7-33.1 degrees C. These values agree closely with Landis' original studies in 1930 [E. Landis (1930) Heart, 15, 209-228]. 3. The mean filtration/reabsorption state of any particular capillary limb was not static because of cardiac, vasomotor and respiratory fluctuations in capillary pressure. From a total of 38 capillaries in which recordings were analysed for 30 s, the fluctuations in pressure were such that 27 capillaries probably had periods of both filtration and reabsorption. 4. Computerized superimposition and coherent averaging of trains of capillary pulses enabled an accurate description of the pulse waveform to be made in three capillaries. This was remarkably similar to waveforms from the radial artery, albeit at reduced amplitude (average 3.6 +/- 3.4 mmHg, mean +/- SD overall). The time for the pulse to travel between the radial artery and the finger capillary was approximately 10 ms, which implies a propagation velocity of several metres per second.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMedDate not supplied

Influence of patient positioning on the l5-l6 mid-laminar distance.

The aim of this project was to determine the effect of patient position on the L5-L6 mid-laminar distance (MLD). The lumbar area of 22 recently euthanatized dogs of various breeds was radiographed in three positions: lateral recumbency with the spine in neutral position, lateral recumbency with the spine flexed in a kyphotic position, and sternal recumbency with the spine flexed in a kyphotic position. Digital images of the radiographs were analyzed using a computer program that allowed measurement of the MLD between L5-L6 in the three positions. The L5 and L6 MLD was significantly larger in sternal recumbency with the spine flexed (142.3 units) than both in lateral recumbency with the spine flexed (138.7 units; P= 0.001) and lateral recumbency with the spine in the neutral position (135.8 units; P < or = 0.001). The MLD in lateral recumbency with the spine flexed was significantly larger than in lateral recumbency with the spine in neutral position (P = 0.005). Positioning a dog in sternal recumbency with the spine flexed produces a significantly larger MLD than in lateral recumbency with the spine flexed; this should simplify needle placement when performing a lumbar puncture.

Animals↗
PubMed2000

Studies of the mechanism of amniotic sac puncture-induced limb abnormalities in mice.

The principal advantage of chorionic villus sampling (cvs) over amniocentesis for the determination of the genetic constitution of the embryo is that it may be undertaken earlier in pregnancy. If carried out too early in pregnancy, it has the risk of inducing craniofacial and limb abnormalities, a condition termed the oromandibulofacial limb hypogenesis (OMFL) syndrome in genetically normal infants. It is believed that the defects observed have a vascular origin, possibly due to anoxia of tissues due to fetal blood loss or thrombus formation at the site of biopsy with distal embolization. We believe that this does not adequately explain the findings from the experimental animal literature involving amniotic sac puncture (ASP). Based on these experimental findings, we have hypothesised that (i) the defects observed following cvs may result from the consequences of oligohydramnios following the inadvertent puncturing of the amniotic sac during this procedure, and (ii) that cleft palate and the postural limb defects observed (e.g., clubfoot and clubhand) are secondary to embryonic/fetal compression. Our experimental studies shed new light on the mechanism of induction of the limb defects seen, but particularly syndactyly. Evidence of hypoperfusion of the peripheral part of the developing limb bud is observed, which interferes with apoptosis that occurs in the digital interzones, or induces an abnormal degree of cellular proliferation and/or tissue regeneration in these sites, possibly because of over-expression of critical genes involved in limb pattern specification. Cleft palate, tail abnormalities and abnormalities of sternal ossification are also observed in our model.

Amniocentesis↗
PubMed1996

Head rotation during internal jugular vein cannulation and the risk of carotid artery puncture.

We undertook a prospective laboratory study to examine the effect of head position on the relative positions of the carotid artery and the internal jugular vein (IJV). Volunteers (n = 12) from departmental staff, 18-60 yr of age, who had never undergone cannulation of the IJV underwent imaging of their IJV and carotid artery. With the subject in a 15 degrees Trendelenburg position, two-dimensional ultrasound images of the IJV and the carotid artery were obtained on the left and right sides of the neck at 2 and 4 cm from the clavicle along the lateral border of the sternal head of the sternocleidomastoid muscle at 0 degrees, 40 degrees, and 80 degrees of head rotation from the midline. The percent overlap of the carotid artery and IJV increased significantly at 40 degrees and 80 degrees head rotation to both the right and left (P < 0.05). Data from 2 and 4 cm above the clavicle did not differ and were pooled. The percent overlap was larger on the left than the right only with 80 degrees of head rotation (P < 0.05). The increased overlap of carotid artery and IJV with head rotation > 40 degrees increases the risk of inadvertent puncture of the carotid artery associated with the common occurrence of transfixion of the IJV before it is identified during needle withdrawal. The IJV frequently collapses with needle insertion. This may result in puncture of the posterior wall of the vessel, and thus of the carotid artery when the two vessels overlap. To decrease this risk, the head should be kept in as neutral a position as possible, that is < 40 degrees rotation, during IJV cannulation.

Adolescent↗
PubMed1978

[Mediastinoscopy in children].

This technique enables the exploration of the mediastinum by the cervical way, but remains an unfrequent examination in children. Among almost 1000 mediastinoscopies made by the authors, the indication concerned only 20 children aged less than 17. Made in a prognostical purpose in most of the cases (16 patients) it gave the diagnosis 14 times. In four cases the mediastinoscopy was carried out as a prognosis during a pre-therapeutics of some hematosarcomas. This method requires a general anaesthesia with intubation, but doesn't differ much from the technic for adults. Besides the supra-sternal way leading to the axial mediastinum (Carlens's technic) other ways are used, particularly the anterior mediastinoscopy--exploring the thymic lodge--and the antero-lateral way through an intercostal space. The mediastinoscope enable the visual control of the lesions, completed with biopsies of the tissues for an histological examination and puncture with a needle for the cytology study. The diagnosis was made in 90% of the cases, sometimes after repeat mediastinoscopy. The failures are due most often to an incertitude in the interpretation of the samples than a badly directed biopsy. There was no surgical incident in our serie. The general morbidity of the examination is 1,5% and the mortality is 0,1% according to the authors. But two anesthetic incidents were observed in children with malignant lymphomas and required the use of reanimation technics. The mediastinoscopy is useful in the tumors of the thymus (10 times), the tumors of the lateral mediastinum (8 times) an hematosarcomas or Hodgkin's disease.

Adolescent↗