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At least 163 records · Page 9Linked to original sources

[Clinical application of a software for the analysis of arterial blood gases graph in 231 patients with chronic obstructive pulmonary disease].

OBJECTIVE: To evaluate the clinical significance of a computer software for the analysis of arterial blood gases graph (ABGG) in chronic obstructive pulmonary disease(COPD). METHODS: The software was developed with Win98 as the operating platform and the visual software Delphi 5.0 from Borland Company, and it was used for evaluation of the changes in arterial blood gases (ABG) of 231 COPD cases. RESULTS: (1) With the software it took only (4.7+/-0.5)s to draw and analyze an ABGG of COPD patients during oxygen inhalation; the time was much shorter than manual analysis (90.2+/-4.9)s, P<0.001. (2) During acute attack, the distributions of the arterial blood gases parameters on ABGG were as follows: 55.4% of cases in the area of insufficient ventilation and deranged gas exchange (area 5), 22.9% of cases in the area of compensated ventilation and deranged gas exchange (area 4), 21.6% of cases in the area of excessive ventilation and deranged gas exchange (area 6). (3) When the COPD patient's condition improved, the location of ABG in ABGG shifted from area 5 to area 4 or area 6. The distributions of the arterial blood gases parameters on ABGG of 106 cases on admission were significantly different from those at the time of discharge. (4) With deterioration of patient's condition, it shifted to area 5. Before death, the arterial blood gases parameters were exclusively in the area 5. CONCLUSION: The computer software for ABGG shortened the time to draw and evaluate ABG during oxygen inhalation, and it could reflect the changes in patient's condition promptly.

Aged↗

[Stereotactic aspiration using coordinate software for hypertensive intracerebral hematomas].

Stereotactic aspiration for intracerebral hematoma has become widely used due to improvements in computed tomography (CT). CT-guided stereotactic aspiration for hypertensive intracranial hematomas was performed in 46 cases. Stereotactic aspiration with coordinate software was carried out among 16 cases. We compared the clinical results of conventional stereotactic aspiration with results of the new method using coordinate software. Using coordinate software, we can examine the route for the target point, as well as the target point of the hematoma before surgery. Therefore we can avoid obstacles such as ventricles and internal capsules. Further, we can aspirate hematoma by using only this one procedure. Mean hematoma aspiration percentage has risen from 44.9 to 87.2% by using coordinate software. Rate of drainage tube insertion after operation has decreased from 90 to 50%. The period of placement of the drainage tube and the frequency of infection due to the drainage tube has become lower, too. Therefore we can say that the outcome of treatment of hypertensive intracranial hematomas is improved by using coordinate software.

Cerebral Hemorrhage↗

Computerizing medical records: software criteria for systems to document patient encounters.

It is difficult to design and build computer systems to document medical care, especially if the entries are to be made by health care professionals. Not all software approaches are equally well suited to the task. Twenty-one specific software characteristics were identified that promote efficient development and support clinical needs. Using a software tool that satisfied these characteristics, we developed a computerized medical chart system that physicians can use to write notes and document patient encounters. The success of this system was due to a good fit between the basic capabilities of the software approach and the requirements of the project. These criteria can serve as the starting point for evaluating or developing other software applications that depend on physician input of clinical information.

Documentation↗

Legal issues associated with pharmacokinetic software.

Legal issues associated with the use of pharmacokinetic computer software are discussed. One issue involves the physician's reliance on the pharmacist, as a drug therapy expert, to provide consultation on drug dosages. Another issue is the problem of liability associated with the software and how this relates to the physician, the pharmacist, and those who designed, manufactured, and sold the software. The legal concept of negligence as it relates to medical computer software is discussed. Although the programmer and the manufacturer are responsible for verifying that the program does what it purports to do, the user must exercise due care in identifying any program limitations that might influence the accuracy of a consultation. Clinical perspective, effective validation techniques, and critical selection will help to ensure that pharmacokinetic computer software is developed, purchased, and used safely and effectively.

Drug Therapy, Computer-Assisted↗

Software selection: can a demonstration computer package help?

Using a demonstration package (demo) is one method of reviewing software which a foodservice manager is considering for purchase. There are a large number of software programs available, and the number is always increasing. Once the foodservice manager has established the criteria for selecting software, the programs which appear to meet those criteria must be evaluated. This article discusses the use of a demo as part of the evaluation process. A demo is a promotional tool used by vendors to demonstrate their software. Part or all of the program, with limitations on the amount of data that may be entered into the software, is normally provided. Advantages and disadvantages of demos are discussed, and the authors' experience using a demo is reported. A program demonstration checklist is provided. The advantages and disadvantages of reviewing the entire program and observing a vendor's demonstration are also discussed.

Food Services↗

[The SINTESI Project: software in cardiovascular prevention].

Coronary heart disease is the most important cause of mortality in adults. New approaches may reduce the cardiovascular risk in population. "SINTESI" is an original data base designed in collaboration with the Italian Group for the Study of Metabolism Disease and Atherosclerosis to improve the evaluation of the major risk factors in the population and to create a data bank for medical research. It runs in Windows. The software includes the following electronics archives: Demographics; History; Follow-up; ECG; Laboratory; Doppler-echocardiography; Stress test-ECT; Ambulatory blood pressure monitoring; Holter-ECG; Nuclear imaging; Vascular echo-Doppler; Hemodynamics; Radiology. We named the most important file "Main Working Area" (MWA). This displays all the most important information on the clinical status of the patients and represents the "console" for using the software. In fact, in MWA "buttons" are displayed to enter all the electronic archives. The software displays graphics and the flow-chart of clinical history. We implemented "routines" for automatic evaluation of several variables. We also simplify the statistical use of the data implementing functions for "query" that permit the management of data bank. The use of this software may facilitate the correct evaluation and stratification of the cardiovascular risk. In conclusion, "Progetto SINTESI" is an easy, synthetic organization of patient's clinical data and a complete data bank. It is our opinion that the use of this software may promote a standard way of collecting a large number of data to improve the stratification of cardiovascular risk.

Adult↗

The questions of organization and software in the "Environment-health of the Ukrainian Population" monitoring.

The dependence of health provision on environmental quality is evident. The scientists of Ukraine have accumulated material regarding the population health level; state control of atmospheric air and the water basin was carried out for many years. However the dependence of health provision on the environment was revealed only in some quantity of ecological-population investigations; the results were not very self-evident. All these reasons stipulated the necessity of organized state control and analysis of information systems on environmental and population health functioning, on a single methodological, technical, and program scheme. From an economical point of view, this system presupposes three levels of information processing: 1) city and countryside, 2) region, and 3) the state as a whole. It is advisable, on each level, to input the information of different periodicity receivings (frequently on the low levels and rarely on the upper ones, but the unification structure of assumed data, its primary statistical processing and using software). Taking into account existing but now insufficient professional level of the system users on low level, the program product must provide the information qualitative processing and receiving of result analyze by the user at the minimum of intellectual expenditures. ThatUs why the software must have a very easy interface, defense from mistakes at the input of inadequate information, dialogical stepped style of communication, developed help system, prompts, commentarie , references. The results must be presented not only in the forms of mathematical tables and numerical meanings, but in the form of graphs and diagrams in two- and three- dimensional realization; the disposal of the results on press must be facilitated. The software must provide the data input with a simple but developed request system, various mathematical processing, forming of resulting report forms in standard form. As a result of logic, mathematical and graphical analysis computer must answer the following questions which are of interest to direct system users as well as to administration responsible for sanitation and optimization of the environment and population health protection, that is: what is the structure of the environment in the analyzed region, what factors have the larger expressiveness; what is the structure of population health (structure of disease incidence) of different age groups; what environmental factors and health indices are important for the further investigations; does the correlation exist between the environmental factors, do they form the clusters; does the correlation exist between the population health indices; what is their comparative informativeness; are there appropriateness in the expressiveness of separate environmental factors and health indices in dynamics; what is the dependence of health indices from the environmental factors at their separate and complex effect; what is the part of contribution of all analyzing factors in a whole to the population health change; what is the contribution of each of this factor; what is the prognosis of the environmental changes on each factor and level of health on each indices; what are the critical factor levels, that are the levels at which the non degradation (subthreshold) of health is guaranteed and at which this health degradation reliably takes place (threshold). Software satisfying all these demands and carrying out all functions mentioned above has been worked out with our participation and has been approved in different regions of Ukraine. We are planning the utilization of this software as the main one in organizing in Ukraine of medico-ecological monitoring system.

Environmental Monitoring↗

MuStaR and other software for locus-specific mutation databases.

As the human genome sequencing project nears completion, there has been a vast increase in the rate at which disease and nondisease associated variant sequences are being sought and detected. This has heightened the need for software with which to accumulate allelic variant (mutation) data, and with which to make the data accessible to the scientific community. Many ad hoc solutions have been developed by those interested in specific genes and diseases, and the creation of central databases which hold data for all genes has provided an alternative repository for some of the locus data. Despite this, few specialised software tools exist for researchers to create their own locus-specific allelic variant databases. This article describes methods available to potential curators, including software systems developed with the sole purpose of generating locus-specific mutation databases. In particular, the authors' own software, MuStaRtrade mark, is described. MuStaRtrade mark allows curators to maintain a database on a laptop computer if desired, while being able to export the data to an automatically generated Website which will run on any cgi compliant Web server. Searching the database and the submission of new mutations are made possible through fill-in Web forms. A number of other software tools which may be of use to curators are also described.

Chromosome Mapping↗

Comparison of four artificial neural network software programs used to predict the in vitro dissolution of controlled-release tablets.

The purpose of this study was to evaluate four commercially available artificial neural network (ANN) software programs: NeuroShell2 v3.0, BrainMaker v3.7, CAD/Chem v5.0, and NeuralWorks Professional II/Plus for prediction of in vitro dissolution-time profiles of controlled-release tablets containing a model sympathomimetic drug. Seven independent formulation variables and three other tablet variables (moisture content of granules, granule particle size, and tablet hardness), for 22 tablet formulations, were used as the ANN model input. In vitro dissolution time-profiles at 10 different sampling times were used as the output. The models' optimum architectures were determined for each ANN software by varying the number of hidden layers and number of nodes in hidden layer(s). The ANN developed from the four software programs were validated by predicting the in vitro dissolution time-profiles of each of the 19 formulations, which were excluded from the training process. Although the same data set was used, the optimum ANN architectures generated from the four software programs were different. Using the four optimum ANN models, the plots of predicted vs. observed percentage of drug dissolved gave slopes ranging from 0.95 to 1.01 and r2 values ranging from 0.95 to 0.99 for all 190 dissolution data points for the 19 training formulations. The difference factors (f1) and similarity factors (f2) between the ANN predicted and the observed in vitro dissolution profiles were also used to compare the predictions for the four software programs. It was concluded that the four programs provided reasonable predictions of in vitro dissolution profiles for the data set employed in this study, with NeuralShell2 showing the best overall prediction.

Delayed-Action Preparations↗

Evaluating foodservice software: a suggested approach.

In an era of cost containment, the computer has become a viable management tool. Its use in health care has demonstrated accelerated growth in recent years, and a literature review supports an increased trend in this direction. Foodservice, which is a major cost center, is no exception to this predicted trend. Because software has proliferated, foodservice managers and dietitians are experiencing growing concern about how to evaluate the numerous software packages from which to choose. A suggested approach to evaluating software is offered to dietitians and managers alike to lessen the confusion in software selection and to improve the system satisfaction level post-purchase. Steps of the software evaluatory approach include: delineation of goals, assessment of needs, assignment of value weight factors, development of a vendor checklist, survey of vendors by means of the vendor checklist and elimination of inappropriate systems, thorough development of the request for proposal (RFP) for submission to the selected vendors, an analysis of the returned RFPs in terms of system features and cost factors, and selection of the system(s) for implementation.

Computers↗

Quantitative comparison and evaluation of two commercially available, two-dimensional electrophoresis image analysis software packages, Z3 and Melanie.

While a variety of software packages are available for analyzing two-dimensional electrophoresis (2-DE) gel images, no comparisons between these packages have been published, making it difficult for end users to determine which package would best meet their needs. The goal here was to develop a set of tests to quantitatively evaluate and then compare two software packages, Melanie 3.0 and Z3, in three of the fundamental steps involved in 2-DE image analysis: (i) spot detection, (ii) gel matching, and (iii) spot quantitation. To test spot detection capability, automatically detected protein spots were compared to manually counted, "real" protein spots. Spot matching efficiency was determined by comparing distorted (both geometrically and nongeometrically) gel images with undistorted original images, and quantitation tests were performed on artificial gels with spots of varying Gaussian volumes. In spot detection tests, Z3 performed better than Melanie 3.0 and required minimal user intervention to detect approximately 89% of the actual protein spots and relatively few extraneous spots. Results from gel matching tests depended on the type of image distortion used. For geometric distortions, Z3 performed better than Melanie 3.0, matching 99% of the spots, even for extreme distortions. For nongeometrical distortions, both Z3 and Melanie 3.0 required user intervention and performed comparably, matching 95% of the spots. In spot quantitation tests, both Z3 and Melanie 3.0 predicted spot volumes relatively well for spot ratios less than 1:6. For higher ratios, Melanie 3.0 did much better. In summary, results suggest Z3 requires less user intervention than Melanie 3.0, thus simplifying differential comparison of 2-DE gel images. Melanie 3.0, however, offers many more optional tools for image editing, spot detection, data reporting and statistical analysis than Z3. All image files used for these tests and updated information on the software are available on the internet (http://www.umbc.edu/proteome), allowing similar testing of other 2-DE image analysis software packages.

Electronic Data Processing↗

Portable image-manipulation software: what is the extra development cost?

A hospital-wide picture archiving and communication system (PACS) project is currently under development at the University Hospital of Geneva. The visualization and manipulation of images provided by different imaging modalities constitutes one of the most challenging component of a PACS. It was necessary to provide this visualization software on a number of types of workstations because of the varying requirements imposed by the range of clinical uses it must serve. The user interface must be the same, independent of the underlying workstation. In addition to a standard set of image-manipulation and processing tools, there is a need for more specific clinical tools that can be easily adapted to specific medical requirements. To achieve this goal, it was elected to develop a modular and portable software called OSIRIS. This software is available on two different operating systems (the UNIX standard X-11/OSF-Motif based workstations and the Macintosh family) and can be easily ported to other systems. The extra effort required to design such software in a modular and portable way was worthwhile because it resulted in a platform that can be easily expanded and adapted to a variety of specific clinical applications. Its portability allows users to benefit from the rapidly evolving workstation technology and to adapt the performance to suit their needs.

Costs and Cost Analysis↗

Software Engineering Code of Ethics and Professional Practice.

The Software Engineering Code of Ethics and Professional Practice, intended as a standard for teaching and practicing software engineering, documents the ethical and professional obligations of software engineers. The code should instruct practitioners about the standards society expects them to meet, about what their peers strive for, and about what to expect of one another. In addition, the code should also inform the public about the responsibilities that are important to the profession. Adopted in 2000 by the IEEE Computer Society and the ACM--two leading international computing societies--the code of ethics is intended as a guide for members of the evolving software engineering profession. The code was developed by a multinational task force with additional input from other professionals from industry, government posts, military installations, and educational professions.

Ethics, Professional↗

The HELIOS medical software engineering environment.

The aim of the HELIOS project is to create an integrated Software Engineering Environment (SEE) to facilitate the development and maintenance of medical applications. HELIOS is made of a set of software components, communicating through a software bus called the HELIOS Unification Bus. The object oriented paradigm is used both as the basic structure for building the software components and as the methodology for modelling, storing and retrieving the entities and procedures used in an application. Development standards include UNIX as operating system and X Window/MOTIF as windowing environment. One of the target applications for the HELIOS prototype is the development of a multimedia medical workstation as a front end to a hospital information system.

Computer Systems↗

A software program for exchanging MR data.

In an MR multicenter project, data exchange is a problem because most MR scanners do not use the same data format or have data export facilities. In the COMAC-BME Concerted Action on Tissue Characterization by MRS and MRI, a subgroup of seven MR centers had a need for data exchange in the form of digital MR images of the human brain. Because there was no common data format, software package was developed for data exchange. This article describes the basic features of the developed software. The software package was written in the language of C and was successfully tested on an IBM-6150 UNIX workstation. The software is currently being tested on the following series of UNIX workstations: SUN SPARC, IBM RS6000, and HP 9000/700.

Animals↗

Object-oriented design of medical imaging software.

A special software package for interactive display and manipulation of medical images was developed at the University Hospital of Geneva, as part of a hospital wide Picture Archiving and Communication System (PACS). This software package, called Osiris, was especially designed to be easily usable and adaptable to the needs of noncomputer-oriented physicians. The Osiris software has been developed to allow the visualization of medical images obtained from any imaging modality. It provides generic manipulation tools, processing tools, and analysis tools more specific to clinical applications. This software, based on an object-oriented paradigm, is portable and extensible. Osiris is available on two different operating systems: the Unix X-11/OSF-Motif based workstations, and the Macintosh family.

Computer Communication Networks↗

The reliability of "Analyze" software in measuring orbital volume utilizing CT-derived data.

INTRODUCTION: Craniomaxillofacial surgeons require to estimate the orbital volume in a variety of clinical situations. This paper evaluates a new method based on software analysis of computerized tomography (CT) scan data. MATERIAL AND METHODS: Five dried skulls with prosthetic globes and periorbita were non-helically scanned in an Elscint 2400 CT scanner. Images obtained were processed using the "Analyze" software package and results compared to the volume of the intraorbital prosthesis as determined by a volume displacement gravimetric method. RESULTS: Estimates of volume produced by the software varied from the gold standard by 0.06-50.44%, with a mean error of 8.8%. CONCLUSION: Despite the use of a variety of scan protocols it was not possible to obtain results with "Analyze" software which were sufficiently accurate for clinical use.

Eye, Artificial↗

Development and evaluation of patient-centered software for a weight-management clinic.

OBJECTIVE: To describe a weight-management clinic software system and to report on its preliminary evaluation. RESEARCH METHODS AND PROCEDURES: The software system standardizes the collection of relevant patient information from an initial medical assessment, weekly clinic visits, and laboratory testing protocol of a medically supervised proprietary meal-replacement program in a university-based referral clinic. It then generates monthly patient feedback reports with graphs of clinical and laboratory parameters to support a patient-centered approach to weight management. After patients and clinic physicians review the data to ensure accuracy, the database is used for subsequent patient feedback reports, reports to referring physicians, quality assurance, and research. Clinic physicians and referring physicians were asked to rate their acceptance of the system. In addition, in a retrospective analysis of data generated by the system, outcomes for patients who received system-generated feedback (n = 620) were compared with those who participated in the program before the introduction of feedback (n = 130). RESULTS: Clinic and referring physicians reported that they had high overall satisfaction with the software and that the system saved them time, and the latter group reported that it decreased laboratory use. Regarding patients, the feedback group had lower dropout rates in the latter half of the program, better rates of attendance, completion of laboratory tests, and weight loss after 8 weeks. DISCUSSION: The software seems to facilitate the effectiveness of the treatment protocol for obesity and generates a high-quality database for patient care, clinic administration, quality assurance, and research purposes.

Ambulatory Care↗