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At least 163 records · Page 9Linked to original sources
PubMed2000

[Effect of cytokines on repair of tendon injury].

OBJECTIVE: The review the effect of cytokines on repair of tendon injury and the relevant mechanism. METHODS: By broadly consulting recent issues about cytokines involved in tendon repair, a variety of cytokines with effects in repairing injured tendon was made and the possible mechanisms were summarized, with unsolved problems discussed. RESULTS: There were many cytokines participated in the procedure of tendon repair, among which insulin-like growth factor (IGF-1), transforming growth-beta 1 (TGF-beta 1) played significant roles. Most of the relevant researches were limited in experimental study in vitro. CONCLUSION: Cytokines possibly can accelerate tendon repair and show great potentials in future clinical application.

Animals↗
PubMedDate not supplied

A new device for flexor tendon injuries.

Managing the treatment of patients with zone II flexor tendon injuries for successful outcomes has always been a challenge for the hand therapist. Working closely with the patient to help ensure follow-through with the protocol is frequently necessary. If a patient is compliant, the therapist's concern then becomes one of "scar wars" (to use a phrase coined by Ken Flowers). Early active range of motion and tendon gliding are critical parts of most programs. This author has developed a new idea in conjunction with the Indiana Hand Center protocol.

Equipment Design↗
PubMed1991

Identification of subclinical tendon injury from ground reaction force analysis.

In this study a method of analysing ground reaction forces was developed to help in the diagnosis of subclinical flexor tendon injury. A Kistler force plate was used to obtain records from a population of Thoroughbreds in National Hunt training over a period of two years. Characteristic features of the force patterns generated were measured and shown to have low variance, both between horses and over a period of two racing seasons in animals that were sound throughout the trial. Specific changes in the loading pattern of the limb, which correlated with injury of the superficial digital flexor tendon, were identified from horses that sustained clinical injury during the study. Retrospective analysis showed that changes became apparent in the force patterns before this group of horses exhibited clinical lameness. This type of analysis provides an objective means of detecting tendon injury at an early stage.

Animals↗
PubMed1999

Decrease in adhesion formation by a single application of 5-fluorouracil after flexor tendon injury.

Using an animal model, the effect of a single intraoperative application of 5-fluorouracil on digital flexor tendon adhesions was assessed. After a standard partial division of the tendon and immobilization with a stitch, the synovial sheath in 30 rabbit tendons was treated with 5-fluorouracil solution (50 mg/ml)-soaked sponge pledgets for 5 minutes. Buffered saline was substituted for 5-fluorouracil in 30 control tendons. The tendons were harvested 1 week postoperatively, and histologic sections were assessed with a light microscope. There was a significant reduction in synovial sheath thickening (p < 0.001), cell counts (p < 0.001) and proportional length of adhesions (p < 0.001) in the treated tendons. The reduction in synovial reaction and adhesion formation using this "one touch" technique presents a novel strategy for the management of the clinical problem of postoperative adhesions complicating tendon injury and repair.

Animals↗
PubMed1998

[Management and after-care of extensor tendon injuries of the hand].

The investigation and management of extensor tendons play a minor role compared to those of flexor tendons. The finger extension does not seem to be as important as the flexion. But the practical value of the hand is determined by both. Different managements are used depending on the level of extensor tendon injury. More distal located injuries require a longer restraint than those, which are located more proximal. On the one hand this depends on the blood supply of the extensor tendon, which is by far better in the lower arm and dorsal hand than peripheral. On the other hand the reason is the different amplitude of gliding of extensor tendons, which decreases from proximal to distal to lower than 1 mm. Therefore the tension on extensor tendon sutures increases from proximal to distal. The varies techniques of extensor tendon reconstruction will be described.

Aftercare↗
PubMed1992

Extensor tendon injuries.

A thorough knowledge of anatomy, injury patterns, repair techniques, and evolving rehabilitation methods is necessary to best treat extensor tendon injuries. These injuries are conceptualized as occurring in one of eight zones, which are numbered distally to proximally in the hand and forearm. Even though surgical technique and rehabilitation are specific in each zone, injuries over and proximal to the proximal interphalangeal joint tend to yield less satisfactory results. Dynamic postoperative extension splinting is one factor that is improving long-term results.

Hand Injuries↗
PubMed1992

Closed tendon injuries of the hand and wrist in the athlete.

Evaluation and treatment of closed tendon injuries in the athlete is usually fairly straightforward if seen in the acute stages. These usually respond well in most cases to nonoperative treatment; a small percentage require initial operative treatment, however. In most cases, continued participation in sports is possible during treatment as long as protective splinting is allowed.

Athletic Injuries↗
PubMed2001

Rehabilitation of flexor tendon injuries by use of a combined regimen of modified Kleinert and modified Duran techniques.

OBJECTIVE: Kleinert (active extension, rubber-band passive flexion) and Duran (passive extension, passive flexion) protocols are two basic types of early motion programs for rehabilitation of flexor tendon injuries. Researchers have been working on various modifications or combinations of these two protocols to improve rehabilitation results. The purpose of this study was to analyze the quality of the functional results of flexor tendon repair after a postoperative regimen of early mobilization by use of a combined regimen of modified Kleinert and modified Duran techniques. DESIGN: Thirty-seven patients (74 digits) with repaired flexor tendon injuries were treated. Functional results of the fingers were evaluated by the Buck-Gramcko system and total active motion measurements. RESULTS: The results were excellent in 73% of the fingers, good in 24%, fair in 1.5%, and none was rated poor. CONCLUSION: Our results are comparable with the previous studies that used various postoperative rehabilitation techniques. This postoperative management provides an effective way of achieving satisfactory results. Patient-assisted passive exercises are very safe and more cost effective than therapist-assisted passive exercises.

Adolescent↗
PubMedDate not supplied

Tendon injury repair in a war wound.

During 18 months of the 1991-1992 war against Croatia, 4425 injured were treated at the Department of Surgery, Osijek University Hospital. Among them 46 had tendon injuries, 20 with tendon laceration and 26 with total rupture. In 12 wounded primary repair was performed, 4 of an extensor tendon, 7 of a flexor tendon and 1 of both flexor and extensor. Four patients with primary flexor tendon repair had a good functional result. In other 34 no primary repair was done. Good function was achieved in 18 cases.

Croatia↗
PubMed1987

Peroneal tendon injury associated with calcaneal fractures: CT findings.

Injury to the peroneal tendons is one of the major long-term complications of intraarticular calcaneal fractures and heretofore has been difficult to diagnose by noninvasive radiography. Retrospective review of CT scans of 24 intraarticular calcaneal fractures, obtained shortly after injury, identified 22 cases (92%) of acute peroneal tendon abnormalities. In most of these cases, multiple findings were present. These included lateral displacement in 14 (58%) of 24, impingement by bony fragments in eight (33%), subluxation or dislocation in six (25%), soft-tissue masses around the tendons representing hematomas or early scar tissue in five (21%), and entrapment of the tendons in three (13%). In 10 cases with long-term follow-up, impingement on the tendons by bony fragments correlated well with the subsequent development of peroneal tenosynovitis, while hematoma around the tendons or lateral displacement of the tendons was clinically insignificant. Thus, CT in the immediate postfracture period, can be used to detect and categorize acute peroneal tendon injuries as well as possibly to predict the likelihood and nature of subsequent development of peroneal tenosynovitis.

Calcaneus↗
PubMed1993

Improved results in zone 2 flexor tendon injuries with a modified technique of immediate controlled mobilization.

The results following primary and delayed primary repair in zone 2 flexor tendon injuries were evaluated in 85 fingers of 79 patients using immediate controlled mobilization post-operatively. In 31 patients a conventional Kleinert technique was used. In the remaining 48 patients a modified technique was used with rubber band traction to all fingers instead of only to the injured one. Also a shorter dorsal splint was used in order to secure extension of the PIP and DIP joints. The results were improved and the time of treatment was reduced.

Adult↗
PubMed2000

Cartilage oligomeric matrix protein (COMP) levels in digital sheath synovial fluid and serum with tendon injury.

Cartilage oligomeric matrix protein (COMP) is a noncollagenous extracellular matrix protein found predominantly in cartilage, but also in tendon, ligament and meniscus. Studies in man have demonstrated that it may be used as a prognostic marker in rheumatoid arthritis and osteoarthritis. The present study investigated whether tendon injury contributes to serum and tendon sheath synovial fluid levels of COMP in horses. COMP levels, analysed by competitive ELISA, in the digital sheath synovial fluid were more than 10-fold higher than in the serum. Levels were significantly raised when tendon damage or sepsis was present within the tendon sheath but showed only mild, statistically insignificant, elevation in cases of tenosynovitis alone. COMP concentrations in serum were found to vary with age. Foals (age < or = 1 year) had significantly (P<0.001) higher levels in comparison to older control horses. Total COMP concentrations in an age-matched group with tendinitis were not significantly different from the control group. Measurements of COMP levels in tendon sheath synovial fluid are therefore useful in depicting processes in tendon tissue, while elevated serum levels are likely to be more representative of joint disease than tendinitis.

Age Factors↗
PubMedDate not supplied

An audit of flexor tendon injuries in zone II and its influence on management.

This paper reports the results of a one-year audit of flexor tendon injuries in zone II managed in a controlled mobilization program. It discusses the rationale for the use of this program and compares results with those of other units. On the basis of these results, the authors suggest that rehabilitation programs for patients with this type of injury should be tailored to individual needs and that trends in management should be carefully evaluated before implementation.

Adolescent↗