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At least 163 records · Page 9Linked to original sources

Prediction of oculocardiac reflex in strabismus surgery using neural networks.

Successfully predicting an oculocardiac reflex (OCR) is difficult to achieve despite various proposed maneuvers. The aim of this study was to test the models built up by neural networks to predict the occurrence of OCR during strabismus surgery in children. Premedication was not given. Atropine 0.01 mg/kg was medicated just before induction. Induction was performed with fentanyl or ketorolac, followed by propofol. Atracurium or vecuronium was given for intubation. Anesthesia was maintained with O2-N2O with continuous propofol infusion. Chi-square test was performed for induction agents, gender, weight, muscle blockade, repaired muscle, number of repaired muscles, duration of operation to detect any association between the occurrence of OCR and to develop the model of neural networks. The multi-layer perceptron, radial basis function and Bayesian backpropagation network were tested. The occurrence of OCR was significantly associated with gender and repaired muscle (p < 0.05). Gender, repaired muscle and age were considered as input for the multi-layer perceptron, radial basis function and Bayesian backpropagation network. Three neural networks had predicted the same correction rate in the occurrence of OCR as being 87.5% overall among 16 patients' records tested. These models are conceptually different in predicting compared to conventional maneuvers, and have the advantage of testing individually and foretelling the propensity. By comparison neural networks use grouped experiential data and predict OCR by the learning rule. Neural networks require a relatively abundant number of experienced and homogenous patients' records to establish an accurate model. The multi-layer perceptron, radial basis function and Bayesian backpropagation modeling network may be an alternative way, and preferable to vagal tone maneuvers if the associated relationships to the occurrence of OCR are more clearly defined.

Adolescent↗

On the structure and initial parameter identification of Gaussian RBF networks.

We consider the efficient initialization of structure and parameters of generalized Gaussian radial basis function (RBF) networks using fuzzy decision trees generated by fuzzy ID3 like induction algorithms. The initialization scheme is based on the proposed functional equivalence property of fuzzy decision trees and generalized Gaussian RBF networks. The resulting RBF network is compact, easy to induce, comprehensible, and has acceptable classification accuracy with stochastic gradient descent learning algorithm.

Algorithms↗

Neuron selection for RBF neural network classifier based on data structure preserving criterion.

The central problem in training a radial basis function neural network is the selection of hidden layer neurons. In this paper, we propose to select hidden layer neurons based on data structure preserving criterion. Data structure denotes relative location of samples in the high-dimensional space. By preserving the data structure of samples including those that are close to separation boundaries between different classes, the neuron subset selected retains the separation margin underlying the full set of hidden layer neurons. As a direct result, the network obtained tends to generalize well.

Algorithms↗

A hierarchical neural network algorithm for robust and automatic windowing of MR images.

A novel hierarchical neural network based algorithm for automatic adjustment of display window width and center for a wide range of magnetic resonance (MR) images is presented in this paper. The algorithm consists of a feature generator utilizing both wavelet histogram and compact spatial statistical information computed from a MR image, a competitive layer based neural network for clustering MR images into different subclasses, two pairs of a radial basis function (RBF) network and a bi-modal linear estimator for each subclass, as well as a data fusion process using estimates from both estimators to compute the final display parameters. Both estimators can adapt to new kinds of MR images simply by training them with those images, which make the algorithm adaptive and extendable. The RBF based estimator performs very well for images that are similar to those in the training data set. The bi-modal linear estimator provides reasonable estimations for a wide range of images that may not be included in the training data set. The data fusion step makes the final estimation of the display parameters accurate for trained images and robust for the unknown images. The algorithm has been tested on a wide range of MR images and has shown satisfactory results.

Algorithms↗

Neural network modeling for surgical decisions on traumatic brain injury patients.

Computerized medical decision support systems have been a major research topic in recent years. Intelligent computer programs were implemented to aid physicians and other medical professionals in making difficult medical decisions. This report compares three different mathematical models for building a traumatic brain injury (TBI) medical decision support system (MDSS). These models were developed based on a large TBI patient database. This MDSS accepts a set of patient data such as the types of skull fracture, Glasgow Coma Scale (GCS), episode of convulsion and return the chance that a neurosurgeon would recommend an open-skull surgery for this patient. The three mathematical models described in this report including a logistic regression model, a multi-layer perceptron (MLP) neural network and a radial-basis-function (RBF) neural network. From the 12,640 patients selected from the database. A randomly drawn 9480 cases were used as the training group to develop/train our models. The other 3160 cases were in the validation group which we used to evaluate the performance of these models. We used sensitivity, specificity, areas under receiver-operating characteristics (ROC) curve and calibration curves as the indicator of how accurate these models are in predicting a neurosurgeon's decision on open-skull surgery. The results showed that, assuming equal importance of sensitivity and specificity, the logistic regression model had a (sensitivity, specificity) of (73%, 68%), compared to (80%, 80%) from the RBF model and (88%, 80%) from the MLP model. The resultant areas under ROC curve for logistic regression, RBF and MLP neural networks are 0.761, 0.880 and 0.897, respectively (P < 0.05). Among these models, the logistic regression has noticeably poorer calibration. This study demonstrated the feasibility of applying neural networks as the mechanism for TBI decision support systems based on clinical databases. The results also suggest that neural networks may be a better solution for complex, non-linear medical decision support systems than conventional statistical techniques such as logistic regression.

Adolescent↗

Using improved neural network model to analyze RSP, NOx and NO2 levels in urban air in Mong Kok, Hong Kong.

As the health impact of air pollutants existing in ambient addresses much attention in recent years, forecasting of air pollutant parameters becomes an important and popular topic in environmental science. Airborne pollution is a serious, and will be a major problem in Hong Kong within the next few years. In Hong Kong, Respirable Suspended Particulate (RSP) and Nitrogen Oxides NOx and NO2 are major air pollutants due to the dominant diesel fuel usage by public transportation and heavy vehicles. Hence, the investigation and prediction of the influence and the tendency of these pollutants are of significance to public and the city image. The multi-layer perceptron (MLP) neural network is regarded as a reliable and cost-effective method to achieve such tasks. The works presented here involve developing an improved neural network model, which combines the principal component analysis (PCA) technique and the radial basis function (RBF) network, and forecasting the pollutant levels and tendencies based in the recorded data. In the study, the PCA is firstly used to reduce and orthogonalize the original input variables (data), these treated variables are then used as new input vectors in RBF neural network model established for forecasting the pollutant tendencies. Comparing with the general neural network models, the proposed model possesses simpler network architecture, faster training speed, and more satisfactory predicting performance. This improved model is evaluated by using hourly time series of RSP, NOx and NO2 concentrations collected at Mong Kok Roadside Gaseous Monitory Station in Hong Kong during the year 2000. By comparing the predicted RSP. NOx and NO2 concentrations with the actual data of these pollutants recorded at the monitory station, the effectiveness of the proposed model has been proven. Therefore, in authors' opinion, the model presented in the paper is a potential tool in forecasting air quality parameters and has advantages over the traditional neural network methods.

Air Pollutants↗

A comparison of some neural and non-neural methods for identification of phytoplankton from flow cytometry data.

Four artificial neural network paradigms (multilayer perceptron networks, learning vector quantization networks, and radial and asymmetric basis function networks) and two statistical methods (parametric statistical classification by modelling each class with Gaussian distributions, and non-parametric density estimation via the K-nearest neighbour method) were compared for their ability to identify seven freshwater and five marine phytoplankton species from flow cytometric data. Kohonen self-organizing maps were also used to examine similarities between species. Optimized networks and statistical methods performed similarly, correctly identifying between 86.8% and 90.1% of data from freshwater species, and between 81.3% and 84.1% of data from marine species. Choice of identification technique must therefore be made on the basis of other criteria. We highlight the way each method partitions the data space and thereby separates the data clusters, and discuss the relative merits of each with reference to complexity of data boundaries, training time, analysis time and behaviour when presented with 'novel' data.

Biometry↗

Wavelet networks for face processing.

Wavelet networks (WNs) were introduced in 1992 as a combination of artificial neural radial basis function (RBF) networks and wavelet decomposition. Since then, however, WNs have received only a little attention. We believe that the potential of WNs has been generally underestimated. WNs have the advantage that the wavelet coefficients are directly related to the image data through the wavelet transform. In addition, the parameters of the wavelets in the WNs are subject to optimization, which results in a direct relation between the represented function and the optimized wavelets, leading to considerable data reduction (thus making subsequent algorithms much more efficient) as well as to wavelets that can be used as an optimized filter bank. In our study we analyze some WN properties and highlight their advantages for object representation purposes. We then present a series of results of experiments in which we used WNs for face tracking. We exploit the efficiency that is due to data reduction for face recognition and face-pose estimation by applying the optimized-filter-bank principle of the WNs.

Journal Article↗

Text-independent speaker verification using Minimal Resource Allocation Networks.

This paper presents a text-independent speaker verification system based on an online Radial Basis Function (RBF) network referred to as Minimal Resource Allocation Network (MRAN). MRAN is a sequential learning RBF, in which hidden neurons are added or removed as training progresses. LP-derived cepstral coefficients are used as feature vectors during training and verification phases. The performance of MRAN is compared with other well-known RBF and Elliptical Basis Function (EBF) based speaker verification methods in terms of error rates and computational complexity on a series of speaker verification experiments. The experiments use data from 258 speakers from the phonetically balancedcontinuous speech corpus TIMIT. The results show that MRAN produces comparable error rates to other methods with much less computational complexity.

Algorithms↗

Convergent decomposition techniques for training RBF neural networks.

In this article we define globally convergent decomposition algorithms for supervised training of generalized radial basis function neural networks. First, we consider training algorithms based on the two-block decomposition of the network parameters into the vector of weights and the vector of centers. Then we define a decomposition algorithm in which the selection of the center locations is split into sequential minimizations with respect to each center, and we give a suitable criterion for choosing the centers that must be updated at each step. We prove the global convergence of the proposed algorithms and report the computational results obtained for a set of test problems.

Algorithms↗

Benchmarking of linear and nonlinear approaches for quantitative structure-property relationship studies of metal complexation with ionophores.

A benchmark of several popular methods, Associative Neural Networks (ANN), Support Vector Machines (SVM), k Nearest Neighbors (kNN), Maximal Margin Linear Programming (MMLP), Radial Basis Function Neural Network (RBFNN), and Multiple Linear Regression (MLR), is reported for quantitative-structure property relationships (QSPR) of stability constants logK1 for the 1:1 (M:L) and logbeta2 for 1:2 complexes of metal cations Ag+ and Eu3+ with diverse sets of organic molecules in water at 298 K and ionic strength 0.1 M. The methods were tested on three types of descriptors: molecular descriptors including E-state values, counts of atoms determined for E-state atom types, and substructural molecular fragments (SMF). Comparison of the models was performed using a 5-fold external cross-validation procedure. Robust statistical tests (bootstrap and Kolmogorov-Smirnov statistics) were employed to evaluate the significance of calculated models. The Wilcoxon signed-rank test was used to compare the performance of methods. Individual structure-complexation property models obtained with nonlinear methods demonstrated a significantly better performance than the models built using multilinear regression analysis (MLRA). However, the averaging of several MLRA models based on SMF descriptors provided as good of a prediction as the most efficient nonlinear techniques. Support Vector Machines and Associative Neural Networks contributed in the largest number of significant models. Models based on fragments (SMF descriptors and E-state counts) had higher prediction ability than those based on E-state indices. The use of SMF descriptors and E-state counts provided similar results, whereas E-state indices lead to less significant models. The current study illustrates the difficulties of quantitative comparison of different methods: conclusions based only on one data set without appropriate statistical tests could be wrong.

Algorithms↗

Distortion correction for x-ray image intensifiers: local unwarping polynomials and RBF neural networks.

In this paper we present two novel techniques, namely a local unwarping polynomial (LUP) and a hierarchical radial basis function (HRBF) network, to correct geometric distortions in XRII images. The two techniques have been implemented and compared, in terms of residual error measured at control and intermediate points, with local and global methods reported in the previous literature. In particular, LUP rests on a locally optimized 3rd degree polynomial applied within each quadrilateral cell on the rectilinear calibration grid of points. HRBF, based on a feed-forward neural network paradigm, is constituted by a set of hierarchical layers at increasing cut-off frequency, each characterized by a set of Gaussian functions. Extensive experiments have been performed both on simulated and real data. In simulation, we tested the effect of pincushion, sigmoidal and local distortions, along with the number of calibration points. Provided that a sufficient number of cells of the calibration grid is available, the obtained accuracy for both LUP and HRBF is comparable to or better than that of global polynomial technique. Tests on real data, carried out by using two different (12 in. and 16 in.) XRIIs, showed that the global polynomial accuracy (0.16+/-0.08 pixels) is slightly worse than that of LUP (0.07+/-0.05 pixels) and HRBF (0.08+/-0.04 pixels). The effects of the discontinuity at the border of the local areas and the decreased accuracy at intermediate points, typical of local techniques, have been proved to be smoothed for both LUP and HRBF.

Algorithms↗

Evolutionary optimization of RBF networks.

One of the main obstacles to the widespread use of artificial neural networks is the difficulty of adequately defining values for their free parameters. This article discusses how Radial Basis Function (RBF) networks can have their parameters defined by genetic algorithms. For such, it presents an overall view of the problems involved and the different approaches used to genetically optimize RBF networks. A new strategy to optimize RBF networks using genetic algorithms is proposed, which includes new representation, crossover operator and the use of a multiobjective optimization criterion. Experiments using a benchmark problem are performed and the results achieved using this model are compared to those achieved by other approaches.

Algorithms↗

Fast quantification of proton magnetic resonance spectroscopic imaging with artificial neural networks.

Accurate quantification of the MRSI-observed regional distribution of metabolites involves relatively long processing times. This is particularly true in dealing with large amount of data that is typically acquired in multi-center clinical studies. To significantly shorten the processing time, an artificial neural network (ANN)-based approach was explored for quantifying the phase corrected (as opposed to magnitude) spectra. Specifically, in these studies radial basis function neural network (RBFNN) was used. This method was tested on simulated and normal human brain data acquired at 3T. The N-acetyl aspartate (NAA)/creatine (Cr), choline (Cho)/Cr, glutamate+glutamine (Glx)/Cr, and myo-inositol (mI)/Cr ratios in normal subjects were compared with the line fitting (LF) technique and jMRUI-AMARES analysis, and published values. The average NAA/Cr, Cho/Cr, Glx/Cr and mI/Cr ratios in normal controls were found to be 1.58+/-0.13, 0.9+/-0.08, 0.7+/-0.17 and 0.42+/-0.07, respectively. The corresponding ratios using the LF and jMRUI-AMARES methods were 1.6+/-0.11, 0.95+/-0.08, 0.78+/-0.18, 0.49+/-0.1 and 1.61+/-0.15, 0.78+/-0.07, 0.61+/-0.18, 0.42+/-0.13, respectively. These results agree with those published in literature. Bland-Altman analysis indicated an excellent agreement and minimal bias between the results obtained with RBFNN and other methods. The computational time for the current method was 15s compared to approximately 10 min for the LF-based analysis.

Algorithms↗

QSAR and classification of murine and human soluble epoxide hydrolase inhibition by urea-like compounds.

A data set of 348 urea-like compounds that inhibit the soluble epoxide hydrolase enzyme in mice and humans is examined. Compounds having IC(50) values ranging from 0.06 to >500 microM (murine) and 0.10 to >500 microM (human) are categorized as active or inactive for classification, while quantitation is performed on smaller compound subsets ranging from 0.07 to 431 microM (murine) and 0.11 to 490 microM (human). Each compound is represented by calculated structural descriptors that encode topological, geometrical, electronic, and polar surface features. Multiple linear regression (MLR) and computational neural networks (CNNs) are employed for quantitative models. Three classification algorithms, k-nearest neighbor (kNN), linear discriminant analysis (LDA), and radial basis function neural networks (RBFNN), are used to categorize compounds as active or inactive based on selected data split points. Quantitative modeling of human enzyme inhibition results in a nonlinear, five-descriptor model with root-mean-square errors (log units of IC(50) [microM]) of 0.616 (r(2) = 0.66), 0.674 (r(2) = 0.61), and 0.914 (r(2) = 0.33) for training, cross-validation, and prediction sets, respectively. The best classification results for human and murine enzyme inhibition are found using kNN. Human classification rates using a seven-descriptor model for training and prediction sets are 89.1% and 91.4%, respectively. Murine classification rates using a five-descriptor model for training and prediction sets are 91.5% and 88.6%, respectively.

Animals↗

Neural-network-based adaptive UPFC for improving transient stability performance of power system.

This paper uses the recently proposed H(infinity)-learning method, for updating the parameter of the radial basis function neural network (RBFNN) used as a control scheme for the unified power flow controller (UPFC) to improve the transient stability performance of a multimachine power system. The RBFNN uses a single neuron architecture whose input is proportional to the difference in error and the updating of its parameters is carried via a proportional value of the error. Also, the coefficients of the difference of error, error, and auxiliary signal used for improving damping performance are depicted by a genetic algorithm. The performance of the newly designed controller is evaluated in a four-machine power system subjected to different types of disturbances. The newly designed single-neuron RBFNN-based UPFC exhibits better damping performance compared to the conventional PID as well as the extended Kalman filter (EKF) updating-based RBFNN scheme, making the unstable cases stable. Its simple architecture reduces the computational burden, thereby making it attractive for real-time implementation. Also, all the machines are being equipped with the conventional power system stabilizer (PSS) to study the coordinated effect of UPFC and PSS in the system.

Algorithms↗

Investigation of the nonlinearity in the heart rate dynamics.

This paper presents the application of a neural network to predict human heart rate. Electrocardiograms were measured from 5 healthy adult human subjects and 5 data sets were constructed calculating instantaneous heart rate from the measured signal. The nonlinear radial basis function neural network was applied to have a one step ahead prediction of the 1000 point heart rate. The results of the prediction are compared to that obtained by a linear autoregressive model. The results show that the neural network performs better than the autoregressive model in predicting heart rate for 2 data sets while for the other 3 data sets the performance of the two models is statistically similar. This indicates that the heart rate may be controlled nonlinearly by the autonomic nervous system.

Adult↗

Prediction of a stable microemulsion formulation for the oral delivery of a combination of antitubercular drugs using ANN methodology.

PURPOSE: The aim of this project was to develop a colloidal dosage form for the oral delivery of rifampicin and isoniazid in combination with the aid of artificial neural network (ANN) data modeling. METHODS: Data from the 20 pseudoternary phase triangles containing miglyol 812 as the oil component and a mixture of surfactants or a surfactant/cosurfactant blend were used to train, test, and validate the ANN model. The weight ratios of individual components were correlated with the observed phase behavior using radial basis function (RBF) network architecture. The criterion for judging the best model was the percentage success of the model prediction. RESULTS: The best model successfully predicted the microemulsion region as well as the coarse emulsion region but failed to predict the multiphase liquid crystalline phase for cosurfactant-free systems indicating the difference in microemulsion behavior on dilution with water. CONCLUSIONS: A novel microemulsion formulation capable of delivering rifampicin and isoniazid in combination was created to allow for their differences in solubility and potential for chemical reaction. The developed model allowed better understanding of the process of microemulsion formation and stability within pseudoternary colloidal systems.

Administration, Oral↗