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PubMed1992

[Surgical aspects of acute aortic dissection].

This paper highlights some of the surgical aspects of acute aortic dissections such as: emergency diagnosis, indications for surgery, reconstructive operative techniques, malperfusion phenomena and necessity for follow-up. Aortic dissection is caused by an intimal tear, called the "entry", and subsequent splitting of the media by the stream of blood. Two lumina are thus created, which may communicate through "re-entries". As this creates severe weakness of the aortic wall, rupture and/or dilatation are the imminent dangers of acute aortic dissection. Acute aortic dissection type A, by definition involving the ascending aorta (Figures 1 and 2), is an absolute indication for emergency surgical treatment, because its natural history shows an extremely poor outcome (Figure 3). Due to impending (intrapericardial) aortic rupture, it may be necessary to limit diagnostic procedures to a minimum. Transesophageal echocardiography is the method of choice for establishing a quick, precise and reliable diagnosis (Figure 4). In stable patients, computed tomography gives additional information about aortic diameters or sites of extrapericardial perforation. Digital subtraction angiography (DSA) shows perfusion of the lumina and dependent organs. The surgical strategy in acute aortic dissection type A aims at replacement of the ascending aorta. Reconstructive techniques have to be considered, especially in aortic valve regurgitation without annuloectasia (Figures 5 and 6). In recent times, the use of GRF tissue glue has reduced the need for teflon felt. Involvement of the aortic arch should be treated aggressively up to the point of total arch replacement in deep hypothermic circulatory arrest as part of the primary procedure (Figure 7). Malperfusion phenomena of aortic branches remain risk-factors.(ABSTRACT TRUNCATED AT 250 WORDS)

Acute Disease↗

PubMed2004

[Interventional treatment of thoracic aortic dissection with stent-graft placement guided by transesophageal echocardiography].

OBJECTIVE: To evaluate the effect and safety of transfemoral stent-graft placement in combination with transesophageal echocardiography (TEE) in treating DeBakey IIIb aortic dissecting aneurysm. METHODS: Eight male patients [mean age (55.8 +/- 10.2) years, range 28-71 years] with DeBakey IIIb aortic dissection were diagnosed and confirmed by magnetic resonance angiography (MRA). With TEE and fluoroscopy monitoring, transfemoral stent-grafts placement was performed with resulting close of the proximal or both proximal and distal ruptures of aortic dissection. The immediate and follow-up results were assessed. RESULTS: Eleven stent-grafts were placed successfully in the 8 patients, the mean diameter of stents was 29.4 (22-38) mm. Three patients had a mild endoleak and 2 patients had a tiny shunt immediately after operation. Ascending aortic dissection occurred in 1 patient after balloon dilation. The mean stay in hospital was 9 days. All the eight patients were followed up and the mean time of follow-up was 10.5 (6-18) months, 4 residual shunts disappeared. No stents displacement or new endoleak occurred. CONCLUSIONS: Transfemoral stent-graft placement in combination with TEE for the treatment of DeBakey IIIb aortic dissection is a promising method, which is safe, effective and with little injury. Its recent and middle term result is satisfactory, but further observation is needed for long term result.

Adult↗

PubMed2004

[Functional evaluation of the selective neck dissection in patients with carcinoma of head and neck].

OBJECTIVE: To investigate comparatively the shoulder function, sensory and cosmetic changes after selective neck dissection (SND), modified neck dissection (MND) or radical neck dissection (RND). METHODS: 157 questionnaires, which involving shoulder function, skin numbness and cosmetic changes were sent to patients with SCC of head and neck who were treated with SND, MND or RND between January 1997 and May 2001. 32 eligible questionnaires were collected which included 32 patients had 43 neck dissection. Among them, SNDs were performed in 23 necks, MNDs in 11 necks and RNDs in 9 necks. RESULTS: The shoulder disability was least in SND necks (13.0%), followed by MND necks (36.6%) and RND necks (66.7%). Similarly, permanent neck anesthetic were found in 17.4% of SND necks, 36.6% of MND necks, and 88.9% of RND necks. Last, only 17.4% of SND necks had cosmetic changes after surgery, while 90.9% of MND necks and 100% of RND necks had cosmetic changes after surgery. CONCLUSION: Patients underwent selective neck dissection had the least damage to the shoulder function, skin sensory and cosmetic.

Carcinoma, Squamous Cell↗

PubMed2004

[Multi-vessel dissection; report of a case].

We report an extremely rare case of multi-vessel dissection including left carotid artery, ascending aorta and thoracoabdominal aorta independently. A 65-year-old man suffered from cerebral infarction due to left carotid artery dissection. Five days later, he complained of severe back pain and was diagnosed as acute DeBakey type IIIb aortic dissection. He had been treated medically. One month later, computed tomography (CT) scan demonstrated DeBakey type II as well as type IIIb aortic dissections. The ascending aorta was replaced on August 8, 2001. Then replacement of the descending thoracic aorta with reconstruction of the eighth and tenth intercostal arteries was performed on September 26, 2001. The left carotid artery dissection has been treated medically.

Aged↗

PubMed2004

[Complete resolution of radiculopathy due to cervical vertebral artery dissection after intravascular treatment: a case report].

The authors report the case of a rare manifestation by vertebral artery dissection. A 15-year-old boy who presented with left shoulder weakness and numbness of the left arm was admitted to our hospital. Neurological examination on admission revealed muscle weakness of the left deltoid muscle and sensory disturbance of the left C5 area. MRI/MRA and 3D-CT angiography demonstrated an aneurysm-like dilatation of the left vertebral artery mainly at the C4/5 level. Partial thrombosis was noted in the dilated artery. The left vertebral angiogram showed that the second and third portions of the left vertebral artery had a dilated pseudo-lumen due to arterial dissection. The pseudo-lumen of the dissected vertebral artery was largest in diameter at the C4/5 level. The patient successfully underwent proximal occlusion of the dissected vertebral artery using detachable balloon and Guglielmi detachable coils. Proximal vertebral artery occlusion using an intravascular technique was regarded as a non-invasive and effective option for patients with a cervical radiculopathy due to cervical vertebral artery dissection.

Adolescent↗

PubMed2004

[The advantages of axillary artery cannulation in surgical treatment of type A acute aortic dissection].

There are more alternative cannulation techniques during surgery of type A aortic dissection. The most frequently used femoro-atrial cannulation method provides limited possibility for brain protection during surgery. This theory is confirmed by relatively high frequency of major brain complications in patients operated on while using this cannulation technique. During the last years cannulationis used more often, as it may provide more protection for the brain than other methods. In 2003 seven patients underwent aortic reconstruction because of type A acute aortic dissection using axillary cannulation. All patients except one were discharged after uneventful recovery. There were no postoperative neurological complications following surgery. We lost one patient due to distal progression of the dissection. He was the only patient with clinical evidence of transient postoperative brain damage. We are strongly convinced that the spectacular improvement in our results for the surgery of type A acute aortic dissection is due to the axillary cannulation, the anterograde flow and the isolated cerebral perfusion. We recommend the axillary cannulation technique as the first choice in type A acute aortic dissection.

Acute Disease↗

PubMed2002

[Application of chlorophyll in the cervical lymph nodes dissection of laryngeal and hypopharyngeal carcinomas].

OBJECTIVE: To investigate the patterns of cervical lymph node metastases from the carcinomas of larynx and hypopharynx. METHOD: Chlorophyll solution was injected submucosally into some portions of the larynx and hypopharynx preoperately as a stain of lymphatic system to help conduct modified neck dissections in 50 patiants with laryngeal or hypopharyngeal carcinomas. Searial sections were performed. RESULT: The cervical lymph nodes were stained into deep green with a color contrast to the ambient structures, which facilitated the operation of neck dissections and the distinction of lymph nodes. Pathologically positive lymph nodes found in 48% of all the cases. The metastases to level I and V were always associated with other levels. By statistical analysis, there was a higher metastaic rate in level II, III, and V (P < 0.01). Overal 1 occult metastases were recorded in 23.5% of No (clinically negative neck)cases. The involvement were located only at level II or III. CONCLUSION: For cN+ (clinically positive neck) patiants, upper and middle jugular vein nodes should be dissected necessarilly,and then appropriate selective neck dissections might be considerd according to the intraoperative findings. For the cN(o) cases with supraglottic or hypopharyngeal carcinomas, it is suggested ipsilateral or bilateral upper and middle jugular vein nodes be dissected according to the clinical status. Chlorophyll as a kind of safe and distinctive stain of lymphatic system can be injected preoperatively routinely.

Adult↗

PubMed1992

[Sudden death presenting cardiac tamponade in a case of coronary dissection].

A case is reported of a 56-year-old man with primary coronary dissection presenting as sudden death due to aortic rupture and cardiac tamponade. He was admitted because of loss of consciousness and chest pain. ECG showed complete atrioventricular block and myocardial infarction. Coronary angiography demonstrated coronary dissection and total obstruction of right coronary artery (RCA). Intracoronary injection of urokinase was not effective for recanalization of RCA. He died suddenly two days later. At autopsy, the proximal site of the ascending aorta was dissected locally and had ruptured into a pericardial space. RCA was torn off. The perivascular area around the torn coronary artery communicated with the dissecting space of the ascending aorta. Histologically, no degeneration or infiltration of inflammatory cells was observed in the media of the aorta and the right coronary artery. Histological change was observed only at the media of the torn site of the coronary artery. The thickness of the media was about half of that at the other site of the coronary artery. This is the third case reported in world medical literature of primary coronary dissection presenting as cardiac tamponade.

Aortic Dissection↗

PubMed1992

[Intravascular ultrasound in patients with suspected aortic dissection: comparison with transesophageal echocardiography].

Thirteen patients with suspected aortic dissection (two women, 11 men, age 61 +/- 10.8 years) underwent transesophageal echocardiography (TEE), intravascular ultrasound (IVUS), angiography, and in part computed tomography (CT). TEE was performed using 3.5 or 3.75 MHz ultrasound transducers. IVUS examination was done using a 6F 20 MHz "rotational-tip" IVUS catheter (Boston Scientific) advanced over a guiding-wire positioned in the ascending aorta by the "side-saddle" technique. In two patients it was not possible to advance the catheter into the abdominal aorta. Of the remaining 11 patients, eight had aortic dissection (six Typ III, one Typ II, and one Typ I, de Bakey classification). Two patients had aortic aneurysms without dissection and one patient had a perforation of the ascending aorta. TEE, CT, and angiography led to the correct diagnosis in all patients, while IVUS failed to provide precise information within the ascending aorta and the aortic arch. Reasons were the limited scanfield of the 20 MHz transducer and the inability to steer and position the IVUS catheter. Contrary to the limited value in the ascending aorta, IVUS could successfully scan the entire descending aorta, including the dissection membrane and the originating vessels, if the max. diameter was less than 4 cm. No adverse effects occurred. Intravascular ultrasound allows to scan the entire aorta in patients with suspected aortic dissection. The current limitations can be solved only by the introduction of steerable and/or low frequency catheters.

Aged↗

PubMed2004

Acute thoracic aortic dissection presenting as sore throat: report of a case.

Acute dissection of the aorta can be one of the most dramatic of cardiovascular emergencies. Its symptoms can occur abruptly and progress rapidly. Prompt recognition and appropriate intervention is crucial. However, not all aortic dissections present with classic symptoms of abrupt chest, back, or abdominal pain, and the diagnosis may be missed. Aortic dissection presenting as a sore throat is quite unusual. A 53-year-old man presented with sore throat as the early symptom of an acute thoracic aortic dissection. Unfortunately, the diagnosis was delayed, and the patient died. Given the high morbidity and mortality after delayed recognition or misdiagnosis, aortic dissection should be considered in the differential diagnosis of a patient presenting with sore throat and normal findings of neck and throat, even when there is no classic symptoms.

Aortic Dissection↗

PubMed2004

Early and long-term results of surgical treatment of type A aortic dissection.

BACKGROUND: Acute aortic dissection is one of the most serious life-threatening conditions, with mortality during the first 48 hours reaching 50%. AIM: To assess short and long-term effects as well as safety of surgical treatment of aortic dissection combined with aortic valve repair. METHODS: The study group consisted of 57 patients (38 males, 19 females, mean age 47.9 +/- 13 years) with dissection of the ascending part of the aorta (type A aortic dissection) who underwent surgery in our institution between 1985 and 1999. Follow-up duration ranged from 2 to 16 years -- mean 6 years. Control transthoracic or transesophageal echocardiography was performed in 37 patients. RESULTS: Early mortality was 21%. There were 12 perioperative deaths and 3 late non-cardiovascular deaths. Three patients underwent repeated surgery due to (1) aortic valve insufficiency, (2) pseudoaneurysm at the site of the anastomosis between proximal part of the vascular prosthesis and the aorta, and (3) fistula between aorta and right atrium. CONCLUSIONS: Aortic dissection type A is more frequent in males than females. The main causative factor is hypertension. Early mortality is significantly higher in patients undergoing emergency surgery compared with elective procedures. Heart failure symptoms (NYHA class) improve postoperatively in the majority of patients. Aortic valve repair is effective and relatively safe, and is an alternative to the aortic valve replacement with coronary arteries reimplantation.

Acute Disease↗

PubMed2005

[Single or staged endovascular stent-graft repair for aortic dissection with multi-tears].

OBJECTIVE: To evaluate the single or staged endovascular stent-graft repair for aortic dissection with multi-tears. METHODS: The stent-grafts were inserted through the femoral artery to seal the tears of dissection. RESULTS: Between January 2001 and June 2004, 8 patients with aortic dissection underwent stent-graft placement. There were 5 tears in one patient, 4 tears in two patients, 3 tears in two patients and 2 tears in three patients. There were 11 tears located at descending thoracic aorta, 11 at abdominal aorta and 4 at iliac artery. Six patients underwent operation in single stage, and 2 in staged maneuver. Total 23 stent-grafts were used, including 20 straight type grafts and 3 bifurcated grafts. Placement of the stent-graft was technically successful in all patients. Follow-up with CT or MRA examination after 3, 6, 12 and 24 months postoperatively showed the dissection disappeared with thrombosis in the false lumen, no endoleak occurred. All patients survived to present. CONCLUSION: Single or staged endovascular stent-graft repair is a promising, safe and effective procedure for aortic dissection with multi-tears.

Adult↗

PubMed2005

[Aortic dissection in elderly patients].

We performed 12 operations for aortic dissection in octogenarians from 1997 to 2004. Male : female = 1 : 11. Mean duration of follow-up is 33 +/- 19 months. As regards the etiology, acute type A aortic dissection was 8, chronic type A aortic dissection was 3 and chronic type B aortic dissection with distal arch aneurysm was 1. Total arch replacement was performed in 2 patients and hemiarch replacement in 10. In all patients with acute type A aortic dissection, hemiarch replacement was performed with the aid of selective cerebral perfusion or deep hypothermic circulatory arrest with retrograde cerebral perfusion. Postoperative respiratory failure was found in 1 patient, re-exploration for bleeding in 1, mediastinitis in 1 and temporary neurological dysfunction in 1. There was no hospital mortality. Two patients were died of respiratory failure 4 and 27 months after surgery. The results were acceptable. We recommend that age should not be the only determinant in deciding whether emergency operation should be performed in octogenarians.

Age Factors↗

PubMedDate not supplied

Emotional impact of cadaver dissection: a survey in a medical college in western Nepal.

OBJECTIVES: Adverse physical and psychological effects to human dissection have been reported in many studies. In Nepal, the basic science subjects are taught in an integrated manner in the first four semesters of the MBBS course. Studies on the attitudes of medical students towards anatomy dissection are lacking in Nepal. The present study was carried out to obtain information on the present and initial perception of medical students on exposure to anatomy dissection and the association, if any, of the perception with demographic factors. METHODS: The study was carried out among the first, second and third semester students at the Manipal College of Medical Sciences, Pokhara using the appraisal of life events (ALE) scale in February 2005. Sixty-three first semester, 57 second and 65 third semester students successfully completed the questionnaire and their responses were taken up for analysis. Information on sex, age, nationality, religion, food habits, occupation of parents and selection procedures of respondents was collected. The parameters loss, challenge and threat were measured on first exposure to dissection and at the time of the study. The scores were compared among different categories of students (p< 0.05). RESULTS: 185 of the 225 students (82.2%) successfully completed the questionnaire. The median initial loss, challenge and threat scores were 2, 19 and 4 respectively. The median present loss, challenge and threat scores were 1, 20 and 0 respectively. The present threat score was higher among second semester students. The initial loss was higher among Indians and the present challenge score was higher among vegetarians. CONCLUSIONS: The loss and threat score were low compared to that reported in a previous study. The challenge scores were higher than those reported previously. Majority of students considered anatomy dissection as a significant life experience and one which was largely positive. Further studies with a larger student population and in other medical colleges are required.

Adult↗

PubMedDate not supplied

Steady state evaluation of aortic dissections: A feasibility study.

PURPOSE: One the main reasons for the limited use of MRI in the evaluation of aortic dissection in emergency conditions is its long execution time. The authors report their experience regarding a new MRI sequence that reduces execution time and avoids the use of contrast medium. MATERIALS AND METHODS: Eighteen haemodynamically stable patients with suspected (16 cases, 3 with confirmed diagnosis of aneurysm) or known aortic dissection (2 cases) underwent in emergency conditions 1.5T MRI with Steady-State sequence (Fast Imaging Employing Steady-State Acquisition: GRE 2D; TR 3.5, TE 1.6; Flip Angle 45, bandwidth 125, matrix 224x224, NEX 1, acquisition time per slice 7 s, thickness 6-8 mm, FOV 38; 2D-GE breath-hold sequence requiring cardiac triggering). The results obtained were compared in terms of diagnostic accuracy and execution time with those of classical MRI examination (black blood T1, FSE T2 and 3D MR-angiography) or multislice CT. RESULTS: The diagnostic accuracy of MRI, both with Steady-State sequence and the ''classical'' technique, and multislice CT in the diagnosis of dissection or aneurysm is equal (100%), whereas execution time is 6, 25 and 6 minutes, respectively. Multislice CT proved to be more accurate than Steady-State MRI in evaluating the renal parenchyma and the extension of the dissection to the renal arteries. CONCLUSIONS: The Steady-State MRI sequence provides a diagnosis of aortic dissection or aneurysmal dilatation in a short time and may represent a valuable alternative to CT in emergency settings, especially in patients with reported contraindications to iodinated contrast media.

Acute Disease↗

PubMed2006

[Significance of level VI neck dissection in surgical operation for thyroid cancer].

BACKGROUND & OBJECTIVE: Patients with thyroid cancer often come along with level VI lymph nodal metastasis. Neck dissection, which includes level VI, is routinely performed on cN1 patients, but whether cN0 patients need routine level VI neck dissection is uncertain. This study was to explore the rule of level VI lymph nodal metastasis in thyroid cancer and the significance of level VI neck dissection in surgical operation for thyroid cancer. METHODS: Clinical data of 130 patients with thyroid cancer, who received level VI neck dissection from Jan. 1988 to Jan. 2000, were analyzed retrospectively. RESULTS: Of the 130 patients, 97 had level VI lymph node metastasis, 14 (10.8%) had post-operative complications, including 4 cases of recurrent laryngeal nerve injury. Multivariate survival analysis indicated that level VI lymph nodal metastasis was correlated to the survival of thyroid cancer patients. CONCLUSIONS: Routine level VI neck dissection may be helpful to improve the survival of thyroid cancer patients. Meanwhile, complication could be decreased by improving surgical skills.

Adenocarcinoma, Follicular↗

PubMed1991

[Vascular complications associated with aortic dissection].

Aortic branch occlusion may constitute the mode of presentation or become an important focus of treatment in patients sustaining acute aortic dissection. The optimal therapeutic approach in patients with acute aortic dissection complicated by cerebral, visceral and peripheral vascular problems, and the implications of such complications, are not well established. We review the outcome in 187 consecutive patients (149 males and 38 females, mean age 58 years) with acute dissection of the thoracic aorta who were admitted and operated on in our department over a 13-year period. We assess the incidence, consequences and specific management of significant stenotic and obstructive lesions of the aorta and its branches. Noncardiac vascular complications occurred in 59 patients (32%); of these complications, 38 were associated with type A dissection (incidence 28%) and 21 with type B dissection (incidence 48%). A trend towards decreasing overall surgical mortality was observed in the second part of the study (1983-1989) compared with the first part (1977-1982) i.e. 28% versus 12%. Although aortic rupture and cardiac tamponade were the strongest correlate of morbidity and mortality, death specifically related to vascular complication was more common when such malperfusion occurred in the carotid, celio-mesenteric and renal circulation. Proximal aortic repair at the site of the intimal tear with obliteration of the false lumen may have restored adequate distal circulation in 27 patients in whom improvement of the visceral or peripheral ischemia was observed after the thoracic aortic repair. Additional procedures (immediately after the thoracic repair or later) were necessary in 15 patients to restore adequate perfusion in the compromised area.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗

PubMed1990

Comparison of medical and surgical therapy for uncomplicated descending aortic dissection.

To guide the choice of medical versus surgical therapy for patients with descending (type B) aortic dissection (tear in the descending aorta without involvement of the ascending aorta), multivariate survival analysis was applied to 136 patients admitted to two medical centers between 1975 and 1988 with acute (n = 89) or chronic (n = 47) descending dissection: group 1, all 136 patients; group 2, 106 patients without rupture, pulse loss, or visceral organ compromise; and group 3, 56 patients from group 2 without major cardiac or renal disease (23 surgical and 33 medical). Group 3 medical and surgical subgroups were well matched for baseline characteristics and were potential candidates for either mode of therapy. By Cox model analysis, significant predictors of mortality were pleural rupture, other dissection complications, increasing age, and cardiac disease (all p less than 0.01). Surgical versus medical therapy was not an independent determinant of survival in any of the three groups for acute or chronic dissection. Survival probabilities for all group 3 patients at 1, 5, and 10 years were 0.94, 0.87, and 0.32 (medical) and 0.90, 0.80, and 0.50 (surgical). Despite the limitations of this retrospective study (including the possibility of undefined treatment selection biases), these data suggest that medical or early surgical therapy is associated with equivalent outcome in selected patients with uncomplicated acute or chronic descending aortic dissection.

Adrenergic beta-Antagonists↗