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PubMed2000

The educational value of consumer-targeted prescription drug print advertising.

BACKGROUND: The case for direct-to-consumer (DTC) prescription drug advertising has often been based on the argument that such promotions can educate the public about medical conditions and associated treatments. Our content analysis of DTC advertising assessed the extent to which such educational efforts have been attempted. METHODS: We collected advertisements appearing in 18 popular magazines from 1989 through 1998. Two coders independently evaluated 320 advertisements encompassing 101 drug brands to determine if information appeared about specific aspects of the medical conditions for which the drug was promoted and about the treatment (mean kappa reliability=0.91). We employed basic descriptive statistics using the advertisement as the unit of analysis and cross-tabulations using the brand as the unit of analysis. RESULTS: Virtually all the advertisements gave the name of the condition treated by the promoted drug, and a majority provided information about the symptoms of that condition. However, few reported details about the condition's precursors or its prevalence; attempts to clarify misconceptions about the condition were also rare. The advertisements seldom provided information about the drug's mechanism of action, its success rate, treatment duration, alternative treatments, and behavioral changes that could enhance the health of affected patients. CONCLUSIONS: Informative advertisements were identified, but most of the promotions provided only a minimal amount of information. Strategies for improving the educational value of DTC advertisements are considered.

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PubMed2001

Direct Observation of Surface-Controlled Self-Assembly of Coordination Cages by Using AFM as a Molecular Ruler We acknowledge the Nanolink Program of the MESA(+) Research Institute (University of Twente), the CNR Nanotechnology Programme, and MURST (Project Molecular Nanoelectronics) for financial support of this work. A special thanks goes to Dr. Maik Liebau (University of Twente) for the preparation of the microcontact-printed substrates and Dr. Frank Geurts (AKZO NOBEL, Central Research Arnhem, NL) for the XPS measurements.

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Journal Article↗
PubMed2001

The Discovery of Polyacetylene Film: The Dawning of an Era of Conducting Polymers (Nobel Lecture) Copyright((c)) The Nobel Foundation 2001. We thank the Nobel Foundation, Stockholm, for permission to print this lecture.

This lecture is not directly related to our discovery and development of conducting polymers to which the Nobel Prize in Chemistry 2000 was awarded. However, I would like to present my previous work that I had carried out just before we reached the discovery of chemical doping. I hope that this will be of use and deepen your understandings by learning what had happened before and how we reached the idea of chemical doping.

Journal Article↗
PubMed2001

"Synthetic Metals": A Novel Role for Organic Polymers (Nobel Lecture) Copyright((c)) The Nobel Foundation 2001. We thank the Nobel Foundation, Stockholm, for permission to print this lecture.

Since the initial discovery in 1977, that polyacetylene (CH)(x), now commonly known as the prototype conducting polymer, could be p- or n-doped either chemically or electrochemically to the metallic state, the development of the field of conducting polymers has continued to accelerate at an unexpectedly rapid rate and a variety of other conducting polymers and their derivatives have been discovered. Other types of doping are also possible, such as "photo-doping" and "charge-injection doping" in which no counter dopant ion is involved. One exciting challenge is the development of low-cost disposable plastic/paper electronic devices. Conventional inorganic conductors, such as metals, and semiconductors, such as silicon, commonly require multiple etching and lithographic steps in fabricating them for use in electronic devices. The number of processing and etching steps involved limits the minimum price. On the other hand, conducting polymers combine many advantages of plastics, for example, flexibility and processing from solution, with the additional advantage of conductivity in the metallic or semiconducting regimes; however, the lack of simple methods to obtain inexpensive conductive polymer shapes/patterns limit many applications. Herein is described a novel, simple, and cheap method to prepare patterns of conducting polymers by a process which we term, "Line Patterning".

Journal Article↗