Persons versus situations in the real-life functioning of chronically institutionalized mental patients.
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AIMS: To use a commercial ELISA kit and an immunoblot assay to investigate the antibody levels of selected members of the Bangladeshi population to Helicobacter pylori protein antigens. METHODS AND RESULTS: Using immunoblotting, high seroprevalence rates were observed in all age groups, although the subjects within the 1-9 years age group had the highest seroprevalence of antibodies to H. pylori antigens. By ELISA, the highest level of seroprevalence was observed in those over the age of 20 years. CONCLUSION: On the basis of these results the overall prevalence rate of H. pylori infection for the whole population was 77.4%; 77.9% for orphan boys and 76% for carers. CagA antibodies were detected in 86% of those with high levels of antibodies to H. pylori antigens. SIGNIFICANCE AND IMPACT OF THE STUDY: A combination of immunoblotting and ELISA was the most efficient means of detecting serum antibodies to H. pylori antigens and could be applied to the screening of human sera for H. pylori-specific antibodies.
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Bran's effectiveness in reducing the need for bowel medication for intermediate care patients was examined at a VA medical center in New York. Twelve older men with chronic constipation and bowel medication use were matched and randomized to receive either bran treatment or usual care (controls). After baseline assessment, six patients were given gradually increasing daily doses of a bran mixture. Results over a 4-month period showed that these patients completely discontinued oral laxative use and had an 80% reduction in total bowel medication use without adversely affecting bowel frequency. The six men who received usual care (controls) experienced no changes.
Of the approximately 2 million elders residing in nursing homes, experts estimate that 49% to 83% are experiencing pain. Elders in nursing homes have a high incidence of cognitive impairment, possibly as high as 50%. The verbalization of pain can be difficult for those with cognitive impairment, and elders with dementia may be undertreated and unknowingly allowed to suffer. This article summarizes what is known about pain assessment in the cognitively impaired elderly who reside in nursing homes. Clinical practice implications were derived from this summary. Until accurate ways of assessing pain are discovered, nurses must be educated to the prevalence of pain in cognitively impaired elders and the subtle ways in which it might be detected. Nursing practice is about eliminating suffering. Relieving suffering in those most vulnerable and unable to express their needs is critical.
Twenty-two apparently healthy Nigerian adolescent girls aged 11-17 years residing in a hostel, were studied over five consecutive days in order to assess their energy intake (EI), energy cost of specific activities and body composition (BC). The mean characteristics of the group were: height 1.58 (SD 0.1, range 1.42-1.68) m, body weight 49.1 (SD 7.9, range 34.0-61.0) kg and BMI 19.5 (SD 2.0, range 16.0-23.0) kg/m2. The food intake of each subject was assessed by direct weighing and its energy value was determined by means of a ballistic bomb calorimeter. BMR values were calculated according to Food and Agriculture Organization/World Health Organization/United Nations University (FAO/WHO/UNU) (1985) equations. Percentage body fat (BF%) values were derived from three skinfold thickness measurements, using population-specific equations. The adolescents' mean daily EI was found to be 6510 (SD 855) kJ/d (138.3 (SD 27.8) kJ/kg body weight per d) which is lower than the FAO/WHO/UNU (1985) calculated energy requirement of 8800 kJ/d for adolescent girls aged 12-14 years. The contributions of specific nutrients and individual meals to the total EI were: carbohydrate, protein and fat, 59.2, 12.5 and 28.3% of energy respectively and breakfast, lunch and supper, 21.5, 41.0 and 37.4% respectively. However, the mean BMR was 5627 kJ/d, which is comparable with that given by FAO/WHO/UNU (1985) for adolescent girls aged 13-14 years. The mean BF% was found to be 21.7. The comparatively low EI of the participants in the present study may be indicative of energy deficiency in their meals. This assumption is also reflected in their BC values. Nevertheless, further studies of this kind on adolescents in Nigeria are needed to confirm these observations.
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The relationship between young non-brain-damaged nonpatients, elderly non-brain-damaged patients and elderly brain-damaged patients and the acquisition and extinction of verbal discrimination conditioned responses were investigated in this study. Four groups of 10 Ss each were used: one group of elderly brain-damaged patients with no speech impairment; one group of elderly non-brain-damaged patients; and one group of young nonpatient Ss used as a comparison group. The three elderly, brain-damaged and non-brain-damaged groups were unable to make a simple verbal discrimination, while the younger nonpatient group had a nearly perfect record of discrimination responses. No significant differences were obtained between the three elderly patient groups.