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At least 1,747 records · Page 97Linked to original sources
PubMed1995

[The endoscopic diagnostic and therapeutic procedure in acute peptic hemorrhages from the upper gastrointestinal tract].

Bleeding gastroduodenal ulcers continue to be a common complication of diseases involving the upper segment of the gastrointestinal tract. In the last few years, with the introduction of fiber gastroscopy as a routine method of study, diagnosing of the underlying cause of hemorrhages is no longer a problem. A total of 959 emergency fibro-gastroduodenoscopies are performed.

Acute Disease↗
PubMed1991

Primary biliary cirrhosis associated with recurrent angiodysplastic lesions in the gastrointestinal tract, the lupus anticoagulant and eosinophilic colitis.

A patient is described with stable primary biliary cirrhosis and recurrent gastrointestinal bleeding due to angiodysplasias in the gastrointestinal tract. This is a very rare disease association. In addition this patient showed two other disease associations, not known in the literature. She also suffered from eosinophilic colitis and had the lupus anticoagulant. These associations have not yet been described in the literature.

Angiodysplasia↗
PubMed1992

[Helicobacter pylori and gastrointestinal tract diseases].

We review the bacteriological, epidemiological and pathogenetic aspects of Helicobacter pylori and related diseases of the gastrointestinal tract. It is concluded that H. pylori seems to be at least one of several etiological factors for diseases such as chronic gastritis and duodenal ulcer. It may also be an important cofactor in the development of gastric carcinoma.

Duodenal Ulcer↗
PubMed1975

Association of an isomeric species of carcinoembryonic antigen with neoplasia of the gastrointestinal tract.

We studied the association between serum levels of an isomeric species of carcinoembryonic antigen and neoplasia of the gastrointestinal tract in 993 patients. With use of an empirically determined threshold, the antigen was found to be elevated in 80.4 per cent of 138 patients with neof other tumors, predominantly lung and breast tumors. Serum levels were elevated in 0.23 per cent of random patients and 0.41 per cent of 725 patients without neoplasia, including those with liver diseases, inflammatory bowel disease and chronic renal disease. The results of this study suggest that this species of carcinoembryonic antigen, and that assay for it offers an improved approach to the diagnosis and management of neoplasia of the gastroinetestinal tract.

Adenocarcinoma↗
PubMed1984

Gastrointestinal bleeding--upper gastrointestinal tract.

There has been growing confidence in the ability of therapeutic endoscopy to control bleeding from the upper gastrointestinal tract. This chapter attempts to review the recently published data on this topic, concentrating on sclerotherapy for variceal bleeding, laser photocoagulation and electrocoagulation for bleeding peptic ulcers, with particular emphasis on the results of published controlled trials which are essential for demonstration of clinical benefit.

Animals↗
PubMed2006

Interleukin 25 regulates type 2 cytokine-dependent immunity and limits chronic inflammation in the gastrointestinal tract.

The cytokine interleukin (IL) 25 has been implicated in the initiation of type 2 immunity by driving the expression of type 2 cytokines such as IL-5 and IL-13, although its role in the regulation of immunity and infection-induced inflammation is unknown. Here, we identify a dual function for IL-25: first, in promoting type 2 cytokine-dependent immunity to gastrointestinal helminth infection and, second, in limiting proinflammatory cytokine production and chronic intestinal inflammation. Treatment of genetically susceptible mice with exogenous IL-25 promoted type 2 cytokine responses and immunity to Trichuris. IL-25 was constitutively expressed by CD4+ and CD8+ T cells in the gut of mouse strains that are resistant to Trichuris, and IL-25-deficient mice on a genetically resistant background failed to develop a type 2 immune response or eradicate infection. Furthermore, chronically infected IL-25(-/-) mice developed severe infection-induced intestinal inflammation associated with heightened expression of interferon-gamma and IL-17, identifying a role for IL-25 in limiting pathologic inflammation at mucosal sites. Therefore, IL-25 is not only a critical mediator of type 2 immunity, but is also required for the regulation of inflammation in the gastrointestinal tract.

Animals↗
PubMed1996

HIV-associated non-Hodgkin's lymphoma of the gastrointestinal tract.

OBJECTIVE: To determine the number of HIV-associated non-Hodgkin's lymphoma (NHL) of the gastrointestinal tract (GI) in a population of HIV-infected patients from a distinct geographic region (southern Alberta, Canada), from 1983 to 1995. The type and location of NHL within the GI tract as well it's affect on survival was examined. Patients with GI HIV-associated NHL were compared to patients with extraintestinal HIV-associated NHL. METHODS: The Southern Alberta HIV Clinic in Calgary (SAC) serves all of southern Alberta which has an estimated population of one million. SAC provided primary care for 1086 patients from January 1983 to August 1995. Data were obtained by reviewing the clinic's data base and patient's charts. RESULTS: Over a 12-yr period, 13 cases of NHL of the GI tract and 26 cases of extraintestinal NHL were diagnosed in the 1086 HIV-infected patients. HIV-associated GI NHL occurred in individuals of similar age, sex, HIV risk factors, incidence of preceding AIDS-defining illnesses and CD4 count compared to those with extraintestinal NHL. The most common presentations of GI NHL were; abdominal pain (77%), abdominal tenderness (77%), weight loss (77%), and GI bleeding (38%). The most common sites of GI involvement were the large bowel (46%), ileum (39%), and stomach (23%). Those with GI NHL survived longer (1.96 +/- 0.50 yr vs 0.95 +/- 0.20 yr, p < 0.05) and were more likely to respond to therapy (72.7% vs 33.3%, p < 0.03) than those with extraintestinal NHL. CONCLUSIONS: This study suggests that; 1) the GI tract is common site of involvement in HIV-associated NHL, 2) HIV-associated GI NHL occurs in similar individuals as HIV-associated extraintestinal NHL, 3) those with HIV-associated GI NHL survive longer and are more likely to respond therapy than those with extraintestinal HIV-associated NHL.

Adult↗
PubMed1974

Cellular immunity, peripheral blood lymphocyte count and pathological staging of tumours in the gastrointestinal tract.

The peripheral blood lymphocyte count has been measured in 74 cases of histologically proven carcinoma of the gastrointestinal tract. The count has been correlated with the pathological stage of tumour spread and the patient's delayed hypersensitivity response to 2.4 dinitrochlorobenzene (DNCB). A statistically significant correlation was found between the peripheral blood lymphocyte count and the response to DNCB. There was linear association between the extent of spread of the tumours and the lymphocyte count. Those patients with low peripheral blood lymphocyte counts tended to have more advanced tumours and a poor response to DNCB. The possible causes of this lymphopenia are discussed.

Adult↗