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At least 1,747 records · Page 97Linked to original sources
PubMed2003

Endoscopic removal of an intranasal ectopic tooth.

Intranasal ectopic teeth are rare and ectopic eruption of teeth can occur in a variety of locations. Commonly seen in the palate and maxillary sinus, they have also been reported in the mandibular condyle, coronoid process, orbital and nasal cavities, and through the skin. With the advent of sinonasal endoscopy in the mid 1980s, and subsequent advances in surgical techniques, endoscopic management of intranasal lesions has become possible. In the current case study, we report a successful endoscopic removal of intranasal ectopic teeth located in the nasal cavity. The endoscopic surgical approach used in this case caused less morbidity than do the more common methods of removing an intranasal ectopic tooth.

Endoscopy↗
PubMedDate not supplied

Differential response of articular cartilage from young growing and mature old mice to IL-1 and TGF-beta.

Osteoarthritic lesions are observed in temporomandibular joint cartilage of ICR mice aged 7 months and older, accompanied by reduced proliferation and matrix synthesis. Transforming growth factor-beta (TGF-beta), is a multifactorial growth factor affecting matrix synthesis and cell proliferation in bone and cartilage, whereas interleukin-1 (IL-1) is involved in cartilage degradation. In order to establish the repair capacity of cartilage in aging, the response of cartilage from young and old animals to TGF-beta and IL-1 was studied. Mandibular condyles from young (1-month-old) and old (18-month-old) mice were cultured for up to 72 h in medium supplemented with TGF-beta1 or IL-1alpha. TGF-beta increased protein (+9.26%) and DNA (+36.0%) contents in young animals and DNA content (+19.49%) in old animals. Incorporations of [(3)H]thymidine and [(35)S]sulfate were enhanced in young (+254% and +116%, respectively) and in old (+22.6% and +6.88%, respectively) and animals and activity of alkaline phosphatase was induced in old animals. Treatment with IL-1 resulted in reduced DNA content in young (-35.76%) and old (-33.33%) animals, but acid phosphatase activity was induced in old animals. It is concluded that TGF-beta can induce anabolic activity even in cartilage from old animals indicating repair response in articular cartilage in aging.

Journal Article↗
PubMed1987

Acceleration of cartilage and bone differentiation on collagenous substrata.

Chondroprogenitor cells of newborn murine mandibular condyles were cultured on top of collagen sponges for up to 18 days. After 24 h in culture, new chondroblasts developed which subsequently matured showing signs of hypertrophy, while the extracellular matrix revealed positive reactivity for type II collagen, cartilage proteoglycans and mineralization. Light and electron microscopy examinations showed signs of new osteoid formation, a feature that was preceded by positive immunohistochemical reaction for type I collagen, fibronectin and bone specific sialoprotein. A close temporal and spatial association was noted between the development of mature, mineralized cartilage and new osteoid. The differentiation of new cartilage and bone cells was linked to an increased activity of DNA synthesis and cellular proliferation. The de novo bone formation was accompanied by increasing rates of alkaline phosphatase activity and uptake of [45Ca] features that were found to be tightly correlated to each other. The collagen substrata appeared also to facilitate the migration of cells, their replication and their subsequent differentiation to their respective cellular lineage. Hence, collagen sponges in vitro appear to serve as a promising substrata for culture systems involved with the growth and differentiation of mineralizing tissues such as cartilage and bone.

Alkaline Phosphatase↗
PubMed2003

Double mandibular osteotomy with coronoidectomy for tumours in the parapharyngeal space.

Removal of deep-lobe parotid tumours from the parapharyngeal space is often difficult because of limited surgical access and the critical vascular and neurologic structures nearby. Mandibulotomy, when necessary, is useful for improving wider visibility and control of the vascular bundle and facial nerve, but may cause damage to the inferior dental and lingual nerves. The double mandibular osteotomy with coronoidectomy gives excellent access and avoids damage to these nerves.

Adenoma, Pleomorphic↗
PubMed2004

Closed treatment of condylar fractures by intermaxillary fixation with thermoforming plates.

We report a new intermaxillary fixation (IMF) method for condylar fractures using a thermoforming plate. Fifteen cases of condylar fracture were selected and thermoforming plates were applied. The patient's recover was uneventful in all 15 cases, and the period of IMF ranged from 7 to 17 days, (mean 12) for the following 7 days IMF was used only at night together with functional jaw training during the day. The outcome was good. IMF using a thermoforming plate may be a useful technique for selected condylar fractures.

Adolescent↗
PubMed1996

Stability of orthognathic surgery: a review of rigid fixation.

The use of rigid fixation with orthognathic surgery was greeted by both excitement and healthy concern when it began to find its way into the literature approximately 10 years ago. The purpose of this paper is to review the literature and make comments based on the experience of the senior author on whether one of the early premises was true. Has rigid fixation improved stability with orthognathic surgery? The authors chose to examine mandibular advancements treated with a bilateral sagittal split osteotomy and maxillary osteotomies treated with a Le Fort I osteotomy. When compared to wire osteosynthesis, rigid fixation has improved stability; however, the individual move associated with the osteotomy must be considered. In some cases, auxiliary techniques should be used to ensure stability. Condylar resorption with mandibular advancement continues to be an area of concern.

Bone Plates↗
PubMed1996

Acquired anterior open bite and facial arthromyalgia: possible aetiology.

The development of an anterior open bite in four patients with facial arthromyalgia is described. There were radiological signs of condylar erosion in three of these cases. It is proposed that the pre-senile destructive arthropathy of the temporomandibular joint, seen in a small proportion of patients with facial arthromyalgia, results from lysis of articular cartilage and bone, secondary to an inflammatory process initiated by the local release of neuropeptides. Occlusal changes, including anterior open bite, may occur if the destructive arthropathy is severe and outstrips dentoalveolar compensation.

Adolescent↗
PubMed1997

Should patients with facial fractures be regarded as high risk for HIV?

OBJECTIVE: To determine the prevalence of HIV seropositivity in patients with facial fractures in Edinburgh, UK. DESIGN: A prospective study of 100 consecutive patients in 1994. SETTING: Department of Maxillofacial Surgery, City Hospital, Edinburgh, UK. SUBJECTS: 100 patients with facial fractures who were willing to participate in the study. MAIN OUTCOME MEASURES: Details of facial fractures. Assessment of risk factors for HIV. The seroprevalence of HIV based on unlinked anonymous testing of saliva. RESULTS: None of the participants were HIV positive on saliva testing. Nine patients were found to have one or more risk factors for HIV. Eight patients had been tested for HIV previously. CONCLUSION: Direct history taking appears to be effective in eliciting risk factors for HIV. A detailed risk factor history should be taken for all patients with facial fractures. Continuation of this study may establish whether or not there is a link between facial bone fractures and HIV seropositivity.

Adolescent↗
PubMed1997

Osteosynthesis of condylar neck fractures: a review of 30 patients.

This article reviews 31 condylar neck fractures in 30 patients stabilized with different types of plates with emphasis on complications associated with different types of plates. Indications for stabilization were predominantly bilateral fractures, shortening of the ascending ramus due to lack of occlusal buttressing and condylar neck fractures associated with panfacial fractures. Stabilization was achieved with a single (23 fractures) or a double adaptation miniplate (4 fractures), a 2.4 mm plate (2 fractures) or a TMJ prosthesis (2 fractures). Eight fractures exhibited complications requiring reoperation (4 plate fractures, 3 cases of screw loosening associated with infection, 1 malposition). Complications occurred exclusively in the fractures stabilized with a single adaptation miniplate. Recommendations for stabilization, therefore, include a double miniplate, a 2.4 plate, a minidynamic compression plate (finger-plate) or a 2.0 mandibular-miniplate. Screws are preferably placed bicortically.

Adolescent↗
PubMed1998

Correction of post-traumatic asymmetry by mandibular angle reduction: report of two cases.

We present two patients with post-traumatic mandibular asymmetry, caused by flaring of a fragment containing the mandibular angle in between two fractures. No occlusal disturbance was evident in either case. Instead of refracturing or ramus osteotomies, the asymmetry was corrected by transoral ostectomy of the mandibular angle with good aesthetic results.

Adult↗
PubMed2000

Open treatment of condylar process fractures: assessment of adequacy of repositioning and maintenance of stability.

PURPOSE: This study was designed to determine how well fractured condylar processes were reduced and the stability of the internal fixation in a group of patients whose fractures were treated by open reduction. PATIENTS AND METHODS: Sixty-one patients treated by open reduction and internal fixation for unilateral condylar process fractures were studied prospectively using Towne's and panoramic radiographs. The radiographs were made before surgery, and immediately, 6 weeks, and 6 months postoperatively. The images were traced and digitized, and the position of the fractured condylar process was statistically compared with the position of the nonfractured condylar process in both the coronal and sagittal planes. Additionally, 2 observers examined the images and assessed these same 2 factors. RESULTS: After surgery, the difference in position between the fractured and nonfractured sides averaged less than 2 degrees (not significantly different), indicating good reduction of the fractures. However, subsequently, between 10% and 20% of condylar processes had postsurgical changes in position of more than 10 degrees. CONCLUSIONS: This study showed that it is possible to anatomically reduce the fractured condylar process, but changes in position of the condylar fragment may then result from a loss of fixation.

Bone Plates↗
PubMed2000

Occlusal results after open or closed treatment of fractures of the mandibular condylar process.

PURPOSE: This study compared the occlusal relationships after open or closed treatment for fractures of the mandibular condylar process. PATIENTS AND METHODS: A total of 137 patients with unilateral fractures of the mandibular condylar process (neck or subcondylar), 77 treated closed and 65 treated open, were included in this study. Standardized occlusal photographs obtained at several postsurgical time intervals were examined and scored by a surgeon and an orthodontist. Standard statistical methods were used to assess differences between groups. RESULTS: Patients treated by closed techniques had a significantly greater percentage of malocclusion compared with patients treated by open reduction, in spite of the fact that the initial displacement of the fractures was greater in patients treated by open reduction. CONCLUSIONS: Based on this study, more consistent occlusal results can be expected when fractures of the mandibular condylar process are treated by open reduction.

Adolescent↗
PubMed2003

Complications of mandibular fractures in an urban teaching center.

PURPOSE: In this study, we compared the complications associated with open and closed treatment of mandibular fractures in an urban teaching center over a 4-year period. PATIENTS AND METHODS: We conducted a retrospective review of mandibular fracture morbidity associated with treatment by the oral and maxillofacial surgery service between 1996 and 2000. A total of 721 fractures were recorded, with 594 fractures available for review. Perioperative and postoperative complications were assessed by reviewing patient charts, operative reports, and radiographs. Complications were classified by location, type of complication, and treatment modality. Standard statistical tests were used to assess differences between the groups. RESULTS: Of the 594 fractures available for review, a total of 79 fractures were noted to have had a complication (13.3%). One hundred five complications were observed in the group of 79 fractures due to more than one complication being associated with a specific fracture (15.8%). Closed reductions accounted for the largest treatment group, representing 341 fractures with 26 complications (7.6%). Miniplate fixation was used in 97 cases, with 23 complications (23.7%). Mandibular plates with or without a superior border miniplate were used in 140 fractures, with 28 complications (20%). The most common complication was wound infection, which occurred in 35 fracture sites, followed by nonunion, which occurred at 30 sites. CONCLUSION: In an urban area with a high prevalence of poor living conditions, substance abuse, and poor patient compliance, the treatment of mandibular fractures by closed reduction resulted in the least number of postoperative complications in all anatomic regions of the mandible. The mandibular angle fracture had the highest overall morbidity rate.

Bone Plates↗
PubMed2003

Inducible nitric oxide synthase and apoptosis-related factors in the synovial tissues of temporomandibular joints with internal derangement and osteoarthritis.

PURPOSE: In this study, we investigated the relationship between oxidative stress and apoptosis in synovial tissues in temporomandibular joint diseases (TMDs), including internal derangement (ID) and osteoarthritis (OA), comparing immunohistochemical, arthroscopic, and histologic findings. MATERIALS AND METHODS: Synovial specimens obtained from patients with ID (31 patients), osteoarthritis (11 patients), and condylar fractures of the mandible (5 patients) during arthroscopy were examined immunohistochemically using antibodies against CD68, inducible nitric oxide synthase (iNOS), Fas, and single-stranded DNA (ssDNA). RESULTS: CD68 and iNOS immunoreactivity were detected mainly in synovial lining cells and subintimal macrophages, and tended to increase with synovial hyperplasia. Fas and ssDNA immunoreactivity was detected mainly in synovial lining cells, and Fas-positive regions exhibited a number of ssDNA-positive cells. Fas expression was significantly greater in fractures than in OA, and ssDNA expression was significantly greater in OA than in ID. Fas expression was significantly greater in iNOS-positive versus iNOS-negative TMJs, and ssDNA expression tended to increase with iNOS expression. CONCLUSION: These immunohistochemical findings suggest that oxidative stress and apoptosis in synovial tissues are involved in the onset and progression of TMDs.

Adolescent↗