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Relative frequency of knowledge of performance and motor skill learning.

This study examined the effects of variations in relative frequency of knowledge of performance (KP) on acquisition, retention, and transfer of form for a multilimb closed sport skill. Two groups received either 100% relative frequency of KP or 33% relative frequency of KP while learning the soccer throw-in skill. Participants were boys between the ages of 11 and 14 years who were unfamiliar with the skill. Participants performed a 30-trial acquisition phase in which KP was provided about one of eight aspects of form. Following acquisition, five trial retention and transfer (to a target at a different distance than experienced in acquisition) tests were administered at 5 min, 24 hr, and 72 hr. Although no group differences were found for accuracy scores, the 33% group had higher form scores in acquisition and all retention and transfer tests. It was concluded that reducing the relative frequency of KP eliminated a dependency on KP to guide performance in acquisition, which was beneficial for maintaining form in conditions in which KP was absent.

Adolescent↗

Right or wrong, familiar or novel in pictorial list discrimination learning.

The interaction between nonassociative learning (presentation frequencies) and associative learning (reinforcement rates) in stimulus discrimination performance was investigated. Subjects were taught to discriminate lists of visual pattern pairs. When they chose the stimulus designated as right they were symbolically rewarded and when they chose the stimulus designated as wrong they were symbolically penalised. Subjects first learned one list and then another list. For a "right" group the pairs of the second list consisted of right stimuli from the first list and of novel wrong stimuli. For a "wrong" group it was the other way round. The right group transferred some discriminatory performance from the first to the second list while the control and wrong groups initially only performed near chance with the second list. When the first list involved wrong stimuli presented twice as frequently as right stimuli, the wrong group exhibited a better transfer than the right group. In a final experiment subjects learned lists which consisted of frequent right stimuli paired with scarce wrong stimuli and frequent wrong stimuli paired with scarce right stimuli. In later test trials these stimuli were shown in new combinations and additionally combined with novel stimuli. Subjects preferred to choose the most rewarded stimuli and to avoid the most penalised stimuli when the test pairs included at least one frequent stimulus. With scarce/scarce or scarce/novel stimulus combinations they performed less well or even chose randomly. A simple mathematical model that ascribes stimulus choices to a Cartesian combination of stimulus frequency and stimulus value succeeds in matching all these results with satisfactory precision.

Adolescent↗

Interocular generalization: a study of mirror-image reversal following monocular discrimination training in the pigeon.

Generalization gradients along a continuum of angular orientation were obtained from four pigeons, following monocular training on a discrimination between a 45 degrees oblique line (S+) and a 135 degrees oblique line (S-). All pigeons were trained on a chain DRO VI 1 schedule of reinforcement. Generalization gradients obtained with the trained and untrained eye were compared. All pigeons responded maximally to the 45 degrees line (S+) when tested with only the trained eye open. During generalization tests of interocular transfer with only the untrained eye open, three pigeons responded maximally to S- (135 degrees ), the mirror-image of the stimulus associated with reinforcement during training (45 degrees ). The other pigeon failed to show interocular transfer of the discrimination. Interocular reversal of left-right mirror-image stimuli has not been reported for any other species.

Animals↗

Stimulus equivalence after inferior temporal lesions in monkeys.

Monkeys with inferior temporal cortex lesions and unoperated monkeys were trained to discriminate pairs of objects and then tested for transfer after the original discriminanda were made larger or smaller, rotated, or presented as two-dimensional projections. The two groups of monkeys transferred equally well to the discriminanda altered in size or orientation, but only the unoperated animals transferred to the two-dimensional representation.

Animals↗

[Evidence-based guidelines as tools for medical knowledge transfer. The work mode of the Medical Knowledge Network evidence.de].

The amount of medical knowledge is growing with increasing speed. Physicians are confronted with more and more--and often useless--information. However, the time lag between the creation of new knowledge and its implementation into daily medical practice is often exceeding a decade. In view of these challenges the knowledge network of the medical faculty of the University Witten/Herdecke is focusing on two different tasks: It provides evidence based medical guidelines in a format that is meant for easy access and use in daily practice. It scientifically explores different ways of presenting and transferring evidence based guidelines in order to develop better and easier ways of implementation. National and international guidelines and studies are screened, evaluated, updated and adapted for its use in the academic network by a team of five university based physicians. In addition, clinical specialists as well as primary care physicians provide expertise for detailed scientific adaptations and for adequate implementation strategies. The implementation process of the guidelines among the faculty based primary care physicians is continuously monitored and evaluated. The main goal of this concept is to create a learning environment for the complex process of medical knowledge transfer.

Decision Making↗

CS modality transfer of two-way avoidance in rats with central and basolateral amygdala lesions.

Post-lesion acquisition of two-way avoidance and subsequent transfer to two warning signals (conditioned stimulus, CS) of different modality were investigated in 60 rats. In Experiment I the animals were originally trained with less salient (darkness) CS, then transferred to more salient compound (darkness and white noise), and finally to white noise CS. The opposite arrangement of the conditioned stimuli (CSi) during the subsequent stages was employed in Experiment II. In control animals, avoidance acquisition was faster and the intertrial responding (ITR) rate lower with the auditory than with the visual CS. Lesioned rats learned avoidance responses more slowly, independently of CS modality. The transfer to other CSi revealed dramatic between-group difference in the level and consistency of avoidance response, shuttle-box latencies and ITR rate. In control animals, transfer to more salient CSi enhanced avoidance performance, whereas change to less salient CS decreased it. Rather small changes in shuttle-box performance and consistency of avoidance response due to CS modality were seen in rats with the basolateral lesions. In contrast, central nucleus injury caused a strong deterioration in the avoidance transfer, especially when the visual CS followed the acoustic one. The results indicate differential involvement of the basolateral and central amygdala nuclei in stimulus-processing mechanisms of instrumental defensive behavior.

Acoustic Stimulation↗

Potential role of a novel psychrotolerant member of the family Geobacteraceae, Geopsychrobacter electrodiphilus gen. nov., sp. nov., in electricity production by a marine sediment fuel cell.

Previous studies have shown that members of the family Geobacteraceae that attach to the anodes of sediment fuel cells are directly involved in harvesting electricity by oxidizing organic compounds to carbon dioxide and transferring the electrons to the anode. In order to learn more about this process, microorganisms from the anode surface of a marine sediment fuel cell were enriched and isolated with Fe(III) oxide. Two unique marine isolates were recovered, strains A1(T) and A2. They are gram-negative, nonmotile rods, with abundant c-type cytochromes. Phylogenetic analysis of the 16S rRNA, recA, gyrB, fusA, rpoB, and nifD genes indicated that strains A1(T) and A2 represent a unique phylogenetic cluster within the Geobacteraceae. Both strains were able to grow with an electrode serving as the sole electron acceptor and transferred ca. 90% of the electrons available in their organic electron donors to the electrodes. These organisms are the first psychrotolerant members of the Geobacteraceae reported thus far and can grow at temperatures between 4 and 30 degrees C, with an optimum temperature of 22 degrees C. Strains A1(T) and A2 can utilize a wide range of traditional electron acceptors, including all forms of soluble and insoluble Fe(III) tested, anthraquinone 2,6-disulfonate, and S(0). In addition to acetate, both strains can utilize a number of other organic acids, amino acids, long-chain fatty acids, and aromatic compounds to support growth with Fe(III) nitrilotriacetic acid as an electron acceptor. The metabolism of these organisms differs in that only strain A1(T) can use acetoin, ethanol, and hydrogen as electron donors, whereas only strain A2 can use lactate, propionate, and butyrate. The name Geopsychrobacter electrodiphilus gen. nov., sp. nov., is proposed for strains A1(T) and A2, with strain A1(T) (ATCC BAA-880(T); DSM 16401(T); JCM 12469) as the type strain. Strains A1(T) and A2 (ATCC BAA-770; JCM 12470) represent the first organisms recovered from anodes that can effectively couple the oxidation of organic compounds to an electrode. Thus, they may serve as important model organisms for further elucidation of the mechanisms of microbe-electrode electron transfer in sediment fuel cells.

Bioelectric Energy Sources↗

Localization of function in corpus callosum: tactual information transmission in Macaca mulatta.

Different portions of the corpus callosum were transected in 28 juvenile rhesus monkeys. These animals were then taught a tactual roughness discrimination task while using their right hands and tested for transfer of training while using their left. Animals with some part of the posterior body region of the corpus callosum preserved exhibited intermediate or high levels of transfer of training. Animals with other portions of the commissures preserved, including the splenium, the anterior body, the genu, and/or the anterior commissure but with the posterior body region transected generally failed to show such transfer. It is concluded that tactual information is transmitted between the hemispheres through the posterior body region of the corpus callosum.

Animals↗

Population dynamics of interacting spiking neurons.

A dynamical equation is derived for the spike emission rate nu(t) of a homogeneous network of integrate-and-fire (IF) neurons in a mean-field theoretical framework, where the activity of the single cell depends both on the mean afferent current (the "field") and on its fluctuations. Finite-size effects are taken into account, by a stochastic extension of the dynamical equation for the nu; their effect on the collective activity is studied in detail. Conditions for the local stability of the collective activity are shown to be naturally and simply expressed in terms of (the slope of) the single neuron, static, current-to-rate transfer function. In the framework of the local analysis, we studied the spectral properties of the time-dependent collective activity of the finite network in an asynchronous state; finite-size fluctuations act as an ongoing self-stimulation, which probes the spectral structure of the system on a wide frequency range. The power spectrum of nu exhibits modes ranging from very high frequency (depending on spike transmission delays), which are responsible for instability, to oscillations at a few Hz, direct expression of the diffusion process describing the population dynamics. The latter "diffusion" slow modes do not contribute to the stability conditions. Their characteristic times govern the transient response of the network; these reaction times also exhibit a simple dependence on the slope of the neuron transfer function. We speculate on the possible relevance of our results for the change in the characteristic response time of a neural population during the learning process which shapes the synaptic couplings, thereby affecting the slope of the transfer function. There is remarkable agreement of the theoretical predictions with simulations of a network of IF neurons with a constant leakage term for the membrane potential.

Action Potentials↗

Chinese-English biliteracy acquisition: cross-language and writing system transfer.

This study investigated cross-language and writing system relationship in biliteracy acquisition of children learning to read two different writing systems-Chinese and English. Forty-six Mandarin-speaking children were tested for their first language (Chinese-L1) and second language (English-L2) reading skills. Comparable experiments in Chinese and English were designed focusing on two reading processes-phonological and orthographic processing. Word reading skills in both writing systems were tested. Results revealed that Chinese onset matching skill was significantly correlated with English onset and rime matching skills. Pinyin, an alphabetic phonetic system used to assist children in learning to read Chinese characters, was highly correlated with English pseudoword reading. Furthermore, Chinese tone processing skill contributed a moderate but significant amount of variance in predicting English pseudoword reading even when English phonemic-level processing skill was taken into consideration. Orthographic processing skill in the two writing systems, on the other hand, did not predict each other's word reading. These findings suggest that bilingual reading acquisition is a joint function of shared phonological processes and orthographic specific skills.

China↗

Teaching baccalaureate nursing students to prevent medication errors using a problem-based learning approach.

An objective of the baccalaureate nursing curriculum at Thomas Jefferson University, Jefferson College of Health Professions is to facilitate nursing students' transfer of medication error knowledge into preventive action in the clinical unit. Using a problem-based learning approach, first-semester students are exposed to situations that reflect the real-world scope and complexity of medication administration and errors. Using the frameworks of Failure Mode Analysis and Human Error Mode and Effects Analysis, student groups identify hypotheses, devise solutions, and develop continuous quality improvement processes to prevent errors and facilitate error reporting. Problem-based learning is used in subsequent clinical experiences throughout the curriculum. This reinforcement, combined with a focus on increasingly complex pharmacological agents and medication calculations, enables students to employ critical thinking skills and develop the confidence necessary for safe, professional practice.

Attitude of Health Personnel↗

Reversing the truth effect: learning the interpretation of processing fluency in judgments of truth.

Repeated statements receive higher truth ratings than new statements. Given that repetition leads to greater experienced processing fluency, the author proposes that fluency is used in truth judgments according to its ecological validity. Thus, the truth effect occurs because people learn that fluency and truth tend to be positively correlated. Three experiments tested this notion. Experiment 1 replicated the truth effect by directly manipulating processing fluency; Experiment 2 reversed the effect by manipulating the correlation between fluency and truth in a learning phase. Experiment 3 generalized this reversal by showing a transfer of a negative correlation between perceptual fluency (due to color contrast) and truth to truth judgments when fluency is due to prior exposure (i.e., repetition).

Cues↗

Same/different abstract-concept learning by pigeons.

Eight pigeons were trained and tested in a simultaneous same/different task. After pecking an upper picture, they pecked a lower picture to indicate same or a white rectangle to indicate different. Increases in the training set size from 8 to 1,024 items produced improved transfer from 51.3% to 84.6%. This is the first evidence that pigeons can perform a two-item same/different task as accurately with novel items as training items and both above 80% correct. Fixed-set control groups ruled out training time or transfer testing as producing the high level of abstract-concept learning. Comparisons with similar experiments with rhesus and capuchin monkeys showed that the ability to learn the same/different abstract concept was similar but that pigeons require more training exemplars.

Animals↗