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At least 1,765 records · Page 98Linked to original sources
PubMed1980

Diagnostic implications of the spatial distribution of colonic mass lesions (polyps and cancers). A prospective colonoscopic study.

A prospective colonoscopic study of 642 consecutive patients demonstrated that 156 (66%) mass lesions including 131 polyps and 25 cancers were located within 60 cm of the anus and 82 (34%) mass lesions including 68 polyps and 14 cancers were located beyond 60 cm, the working length of the rigid sigmoidoscope. One hundred twenty-one (61%) polyps and 14 (36%) cancers were located above 25 cm but less than 60 cm from the anus, the working length of the flexible sigmoidoscope. Sixty-eight (34%) polyps and 14 (36%) cancers were located beyond the reach of the flexible sigmoidoscope. Although the flexible sigmoidoscope detects more lesions than the rigid sigmoidoscope, 50% of colon cancers located beyond detection by the rigid sigmoidoscope would not have been detected with the flexible sigmoidoscope. Of all mass lesions located beyond 25 cm, 38% would not have been detected with the use of the flexible sigmoidoscope. It appears that total colonoscopy rather than flexible sigmoidoscopy must play an increasingly prominent role in the evaluation of patients with suspected colonic mass lesions.

Colonic Neoplasms↗
PubMed1993

Streptococcus bovis does not selectively colonize colorectal cancer and polyps.

The objective was to determine if Streptococcus bovis selectively colonizes colorectal cancer and polyps. Stools were submitted before colonoscopy; fluid and selected tissue biopsies obtained during colonoscopy were cultured for S. bovis. The setting was a large multispecialty clinic. Outpatients undergoing colonoscopy for suspected colorectal cancer and polyps were the participants. Forty studies on 35 patients were performed. One of 35 stools (2.9%) obtained before colonoscopy yielded S. bovis. S. bovis was cultured from three of 40 fluid aspirations (7.5%), one of 33 adenomas biopsied (3%), none of six adenocarcinomas, none of 14 nonneoplastic polyps, one of 40 (2.5%) biopsies from normal mucosa adjacent to an adenoma, and none of 40 mucosal biopsies remote from any lesion. These data do not support selective colonization of colorectal neoplasms by S. bovis.

Adenocarcinoma↗