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[Anal sphincter electromyography, bulbocavernosus reflex and pudendal somatosensory evoked potentials in diagnosis of neurogenic lumbosacral lesions with disorders of bladder and large intestine emptying and erectile dysfunction].

The diagnostic value of anal sphincter electromyography (EMG), electrical bulbocavernosus reflex (BCR) and pudendal somatosensory evoked potentials (SEP) was studied in 16 male patients with disturbances of bladder function or defecation or with erectile dysfunction (ED) of at least several weeks' duration. All 16 patients had proven neurogenic disorders in the lumbosacral region. Eleven presented with bladder dysfunction, four with defecation problems, and nine with ED (some had more than one symptom). Fifteen patients had a pathological sphincter EMG, 14 patients a pathological BCR, and six patients a pathological pudendal SEP. Thus, the sphincter EMG was the most sensitive technique in the diagnosis of chronic pudendal lesions. However, pure afferent lesions cannot be detected by the sphincter EMG. In this case, the BCR, using unilateral stimulation of the dorsal nerves of the penis, provides the opportunity to distinguish between afferent and efferent lesions of the sacral reflex arc.

Adult↗

Totally extraperitoneal laparoscopic lumbar sympathectomy: an initial case report.

A 27-year-old man with a diagnosis of Buerger's disease presented with vasospastic symptoms of coldness and pain at rest of his right foot. Physical examination of his affected limb revealed absent popliteal pulse, cool skin hyperhidrosis and dry gangrene of the big toe. He had been operated on for a ruptured liver and liver abscess 20 years ago. He was scheduled for totally extraperitoneal laparoscopic lumbar sympathectomy on July 26, 1994. The technique was performed under general anesthesia and the patient was put in a supine position with slight extension between the rib and the iliac crest. The working space was created by digital blunt dissection and direct insufflation of carbon dioxide. The right sympathetic trunk was found between the medial edge of the psoas muscle and inferior vena cava. The L2, L3, L4 sympathetic ganglia were identified above the vertebral column and meticulously dissected cephalocaudally. Based on the concept of traditional approach, we believe that this laparoscopic technique is relatively safe and should become the procedure of choice in the future.

Adult↗

[Painful bilateral lumbar radiculoplexopathy associated with Epstein-Barr virus infection].

We report a case of polyneuropathy caused by primary Epstein Barr virus (EBV) infection in a 57-year-old patient. The primary EBV infection was confirmed by serology tests and EBNA (Epstein-Barr nuclear antigen) seroconversion. The main clinical sign was a highly painful subacute, bilateral lumbar radiculoplexopathy with amyotrophy which responded to corticosteroids and complement treatment within a few months. The association of left facial paralysis, neurophysiological signs of polyradiculopathy and elevated protein levels in the cerebrospinal fluid demonstrate the variability of peripheral neurological involvement in the same subject with EBV infection. This case also demonstrates the poorly limits of dysimmune polyneuropathies, including lumbar radiculoplexopathy which can be considered as an exceptional variant.

Herpesviridae Infections↗

Estrogen induces axonal outgrowth in the nucleus retroambiguus-lumbosacral motoneuronal pathway in the adult female cat.

In 1995, we discovered a new pathway in the cat, which originates from the nucleus retroambiguus (NRA) and terminates in a distinct set of lumbosacral hindlimb, axial, and pelvic floor motoneuronal cell groups [VanderHorst VGJM, Holstege G (1995) Caudal medullary pathways to lumbosacral motoneuronal cell groups in the cat: evidence for direct projections possibly representing the final common pathway for lordosis. J Comp Neurol 359:457-475]. The NRA is a compact group of interneurons located laterally in the caudal medulla oblongata. Its projection to lumbosacral motoneurons is thought to represent the final common pathway for male mounting and for female receptive or lordosis behavior. However, females only display lordosis behavior. However, females only display lordosis behavior when they are in estrus, which suggests that the NRA-lumbosacral pathway is only active during estrus. This raised the question of whether estrogen affects this pathway. The effect of estrogen on the NRA-lumbosacral projection was studied light microscopically, using wheat-germ agglutinin horseradish peroxidase (WGA-HRP) as a tracer. The rubrospinal pathway served as control. The density of labeled NRA fibers in their target hindlimb motoneuronal cell groups appeared abundant in estrous and very weak in nonestrous cats. Such differences were not found in the rubrospinal pathway. For electron microscopical study, the NRA projection to the semi-membranosus motoneuronal cell group was selected. In this cell group, an almost ninefold increase of labeled profiles was found in estrous versus nonestrous cats. Moreover, the semimembranous motoneuronal cell group contained labeled growth cones in estrous, but not in nonestrous, cats. The present study is the first to show that estrogen induces axonal outgrowth of a precisely identified pathway in the adult mammalian central nervous system. The possible mechanisms underlying this outgrowth are discussed.

Animals↗

Posterior sacral rhizotomy and intradural anterior sacral root stimulation for treatment of the spastic bladder in spinal cord injured patients.

PURPOSE: The efficacy of intradural sacral posterior rhizotomy combined with intradural sacral anterior root stimulation in the treatment of the neurogenic hyperreflexic bladder was evaluated. MATERIALS AND METHODS: We reviewed 10 spinal cord injured patients who underwent surgery between September 1990 and February 1994. Bladder function was compared preoperatively and postoperatively. Intraoperative data on electrostimulation of the detrusor and striated muscles were analyzed. RESULTS: Stimulation of the anterior S3 and S4 roots was mostly used to empty the bladder (7 of 10 cases). Preoperative reflex incontinence disappeared in all patients postoperatively. Mean postoperative bladder capacity increases and mean postoperative post-void residual decreases were at least 340 ml. (p < 0.01) and 140 ml. (p < 0.01), respectively. Preoperative vesicorenal reflux disappeared in 2 and improved in 3 cases after sacral deafferentation. Autonomic hyperreflexia, which was present preoperatively in 6 patients, never disappeared but significantly improved after deafferentation. No major complications were noted postoperatively. CONCLUSIONS: Intradural sacral posterior rhizotomy combined with intradural sacral anterior root stimulation is a valuable method to treat the hyperreflexic bladder with incontinence resistant to conservative therapy in spinal cord injured patients. Autonomic hyperreflexia was decreased but not suppressed by posterior sacral rhizotomy.

Adolescent↗

Retroperitoneal endoscopic neurectomy for nerve entrapment after hernia repair.

BACKGROUND: Entrapment neuralgia after open and laparoscopic hernia repair occurs in about 1-2 per cent of patients. If the pain persists accurate identification of the nerve involved and surgical treatment is an option. Entrapment neuralgia of the genital branch of the genitofemoral nerve and ilioinguinal nerve occurs, but damage to the femoral branch of the genitofemoral nerve, the lateral femoral cutaneous nerve and the femoral nerve is also described. This paper reports an endoscopic technique for neurectomy. METHODS: A balloon catheter is inserted bluntly into the lower retroperitoneum and insufflated to create a work space. Neurectomy is performed under endoscopic guidance. RESULTS: Three men with a mean age of 39 years were treated using this technique. A neurectomy of the genitofemoral nerve was performed in all three and in one neurectomy of the ilioinguinal nerve was also done. The mean operating time was 70 min and all the patients were completely pain-free after surgery. All patients were discharged within the first 2 days after operation and there were no complications. CONCLUSION: This retroperitoneal endoscopic technique is proposed as a new surgical approach for treating entrapment neuralgia. It is simple and effective at relieving symptoms.

Adult↗

[The developmental characteristics of the arterial collaterals under ischemia and sympathectomy of the hindlimbs in dogs].

Thrombosis of hind legs arteries and high lumbar desympathization were induced in dogs kept naturally (unleashed and receiving usual meal) and in the vivarium for studying the regularities of collateral blood circulation 7-720 days after the experiment. Roentgenovasography and kinoangiography allowed to assess anatomicofunctional state the vascular system. Results of the examinations performed demonstrated acute and chronic ischemia coupled with significant disorders in local hemocirculation developing in experimental arterial thrombosis and desympathization of the extremity. Natural conditions (usual meal). fresh air, active movement, staying unleashed and so on) were positive for preventing postischemic disturbances in the experimental animals.

Animals↗

[L5-S1 herniated disk migrated to the anterior part of the right sacral wing with compression of the right lumbosacral roots].

PURPOSE OF THE STUDY: The goal of this study was to report an exceptional case of far lateral and anterior disc herniation at L5-S1 level. CASE REPORT: A 47 year-old man presented a right L5 radicular pain with motor deficit of tibialis anterior and extensor hallucis longus resisting to medical management. Standard X-rays showed a degenerative process of L5-S1 disc. The CT scan was at first considered as normal. The myelogram was normal. A second study of the CT scan showed an opacity next to the L5 right root in front of the sacral wing. A discography combined with CT scan was then performed showing the migrated herniated disc from L5-S1 to the anterior part of the right sacral wing in contact with L5 root. RESULTS: Surgery was performed by transperitoneal approach and needed a difficult dissection of hypogastric vessels. The herniated disc was found behind the L5 root. A L5-S1 disc excision and arthrodesis with iliac grafts were performed. The result has been very good with relief of the pain and recovery of the palsy within a month. CONCLUSION: The lecture of a CT scan should include the far extraforaminal zone if there is no compression in the spinal canal. Such an anterior migration of an herniated disc has not been already described as far as we know.

Diskectomy↗

[A propos of an unusual case of lumbar-pelvic dislocation in a suicidal jumper].

PURPOSE OF THE STUDY: We report a particular case of lombo-pelvic dislocation in a suicidal jumper, characterized by a distal sacral fracture associated with bilateral fractures of both iliac wings. To our knowledge, it has yet not been described. MATERIAL AND METHODS: The patient was a 27 years old individual. On admission, he sustained the following injuries: hemodynamic shock with intraperitoneal bleeding due to disruption of the triangular ligament of the liver, which resolved with blood transfusions and did not require surgical treatment pelvic fractures initially identified as transverse fractures of both iliac wings, with bilateral avulsions of sciatic spines a compression fracture of the first lumbar vertebra without neurologic complication. In the intensive care unit, evolution was favorable. However, an incomplete cauda equina syndrome was noticed: the anal sphincter was flacid but perianal sensation to pinprick was conserved. An electromyogram showed that the latence of perineal reflexes was increased. The fracture and its displacement were recognized secondarily. A pelvic C.T. exhibited an increases in the antero-posterior dimension of the pelvic ring, due to a distal-displaced transverse sacral fracture. The proximal fragment of the sacrum remained attached to the iliac wing since sacro-iliac joints were intact, iliac wings had tilted forward, and the distal tip of the proximal sacral fragment was driven backward and inferiorly. RESULTS: The patient was maintained in the supine position during 3 months. He then rapidly recovered normal function of his lower limbs. He had normal gait patterns and pelvic static. He did not complain of any pain. Finally, the neurological deficit disappeared and he regained full sexual function and complete control of micturition. DISCUSSION: We think that this fracture should be considered as a variety of suicidal jumper's fracture described by Roy Camille et al. It has the same displacement as type 2 fracture in Roy Camille classification. In the emergency room, diagnosis is difficult, based on usual AP pelvic roentgenograms. A bilateral fracture of iliac wings in a suicidal jumper, especially if associated with bilateral sciatic spine avulsions, is an indication to a pelvic C.T.. A neurological perineal deficit should be ruled out. In our case, the perineal deficit can be attributed to the stretching of sacral roots resulting from a posterior displacement of the sacrum. The favorable evolution suggests that surgery may be not required, and there is no evidence in the literature that it would help neurological recovery. In distal fractures, the sacral canal is not narrowed, and a sacral laminectomy appears therefore not indicated. CONCLUSION: We have described a particular type of transverse fracture of the pelvis, which, in our mind, should be put in the same category as type 2 transverse fractures of the sacrum described by Roy Camille and al, in the suicidal jumper. Since there is no compression of sacral roots into the sacral canal, prolonged bedrest is likely to be the better treatment.

Adult↗

[Right laparoscopic lumbar sympathectomy].

Laparoscopic lumbar sympathectomy was performed on a young man with thromboangiitis obliterans (Buerger's disease). The surgeons disposition, trocars placement and dissection technique are described in detail. The retroperitoneal approach was done in a manner similar to laparoscopic properitoneal hernia repair. The operation can be carried out with common laparoscopic equipment (for cholecystectomy) and offers the benefits of minimally invasive surgery.

Adult↗

[Left lumbar sympathectomy via the retro-pneumoscopic approach. The technical considerations].

Retropneumoscopic lumbar sympathectomy is performed with an increasing frequency as a treatment of chronic obstructive arteriopathies; though the method has limited indications. We present the operative technique as it was performed în the Colţea Surgical Department in 2 patients. We highlights on difficulties advantages and disadvantages of the method.

Arterial Occlusive Diseases↗

Microanatomy of the structures contributing to abdominal cutaneous nerve entrapment syndrome.

BACKGROUND: Family physicians commonly see patients who complain of abdominal pain, the cause of which cannot be readily diagnosed. Often this pain results from abdominal cutaneous nerve entrapment syndrome. METHODS: Photomicrographs were obtained of the pertinent structures of the ninth thoracolumbar nerve where it passes through the rectus muscle channel. Standard hematoxylin and eosin staining techniques were used after the paraffin autopsy tissue block was positioned to show the entire length of the rectus neurovascular bundle from anterior to posterior surfaces of the muscle (anatomically front to back). Gomori trichrome staining with aniline blue was also done to differentiate further the connective tissue structures. RESULTS: The photomicrographs presented here support the first author's earlier clinical and gross anatomic findings, especially regarding the fibrous ring in the rectus muscle, through which the neurovascular bundle travels. Special attention is given to the rectus fibrous ring, which is so important in producing the syndrome of abdominal cutaneous nerve entrapment. This structure is clearly delineated, and its role in the pathophysiology of this syndrome is described. CONCLUSIONS: Three pictures presented here show the relevant microstructures involved in abdominal cutaneous nerve entrapment syndrome. The photomicrographs confirm the existence of a fibrous ring within which the neurovascular bundle can move freely. If this bundle is pushed or pulled too far from behind or in front, however, compression of the bundle against the ring causes nerve ischemia and symptoms of abdominal cutaneous nerve entrapment. Family physicians can save their patients unnecessary pain and expense by being aware of this syndrome.

Abdominal Muscles↗

[Synovial cyst in the lumbar facet joint. A rare cause of lumbar-sciatic pain].

Synovial cysts of the facet joints are uncommon lesions which may be asymptomatic or present as low back pain, with or without radicular symptoms. They are considered to be secondary to trauma or degenerative joint disease, and they occur more frequently in patients with spondylolisthesis. Diagnosis is normally achieved with computed tomography or magnetic resonance, which show a cystic lesion located laterally adjacent to the facet joint. We review the literature and report a patient who presented with first sacral nerve root symptoms attributable to a ganglion cyst of the left L5 S1 facet joint. Treatment was curative and consisted in excision of the cyst.

Female↗

[Analysis of pudendal nerve somatosensory evoked potentials in the diagnosis of neurogenic impotence].

OBJECTIVE: To determine the utility of the somatosensorial evoked potentials of the pudental nerve in the diagnosis of neurogenic impotence. METHODS: 129 patients with impotence were evaluated by physical examination and neuroandrologic profile. The neuroandrologic profile was assessed by bulbocavernous electromyography, determination of S2-S4 evoked potentials, analysis of the somatosensorial potentials of the pudendal nerve, cavernous smooth muscle electromyography (SPACE), sympathetic skin response and cystometry. RESULTS: The patients with a neurologic lesion presented a significantly longer latency time of the somatosensorial potentials than those with no neurologic lesion. The sensitivity of the somatosensorial potentials was 63% and the specificity was 98%. The sensitivity could be enhanced without significantly lowering specificity by taking 49 msec as the upper limit of normal values in latency time. The determination of the voluntary anal control in the diagnosis of neurogenic impotence was found to have a high specificity (93%), but a low sensitivity (42%). CONCLUSION: The determination of the somatosensorial potentials, unlike other techniques, could allow diagnosis of lesions of the suprasacral inneveration in the evaluation of neurogenic impotence. The evoked somatosensorial potentials of the pudendal nerve and physical examination have the inconvenience of their low sensitivity in regard to the diagnosis of neurogenic lesion in impotence, mainly because some conditions only affect the peripheral autonomic innervation and the somatic element is spared.

Anal Canal↗

[Sympathetic tonus and lumbar sympathectomy in arteriosclerosis obliterans of the arteries of the lower extremities].

The Doppler laser flowmetry was used in order to study the microcirculation in the skin, muscles and bone marrow at different stages of obliterating atherosclerosis of the lower extremity arteries. Progress of the disease is characterized by a decrease of the absolute indices of blood flow in combination with disturbed regulation of vascular tension. The lumbar sympathectomy causes intensification of microcirculation not only in the skin, but also in the muscular and bone marrow tissues.

Arteriosclerosis Obliterans↗