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PubMed1991

The histogenesis of inflammatory fibroid polyps of the gastrointestinal tract.

Inflammatory fibroid polyps are lesions occurring in the submucosa of the gastrointestinal tract. These lesions have been identified by a variety of names, indicative of their uncertain histogenesis. Three cases were studied by light microscopy and cytochemistry and, in one case, by electronmicroscopy. The most characteristic feature consisted of concentric fibrovascular structures. Peroxidase reaction for muscle actin and Ulex europeus agglutinin was positive in the two main cellular components. Electronmicroscopy revealed that the two principal cell constituents were endothelial and myocytic cells. These observations support the conclusion that inflammatory fibroid polyps are lesions of vascular origin.

Actins↗

PubMed1990

[Proctoscopic versus histologic diagnosis of rectal polyps].

On the basis of the endoscopic appearance, 71 rectal polyps were assessed as adenomata or non-neoplastic polyps, after which the endoscopic diagnosis was compared with the results of histological examination. The diagnosis based on macroscopic examination of the polyps proved correct in only 62% of the cases. It is concluded that the diagnosis of adenoma cannot be established solely on the proctoscopic appearance of a polyp and, as adenomata are premalignant, removal of all polyps found at proctoscopy is recommended.

Adenoma↗

PubMed1979

[Adenomatous polyposis of the stomach associated with familial adenomatous polyposis of the colon].

A case of adenomatous polyposis of the stomach associated with familial polyposis of the colon is presented. The relevant literature is reviewed and the data thus collected (with the exception of definitely non-adenomatous, extracolic cases) are presented in tables, depending on whether familial polyposis of the colon or Gardner's syndrome was the accompanying form. A systematic account is given of the association and reference is made to simple polyposis of the stomach, and that of the duodenum. Close attention is paid to the question of diagnosis, the risk of cancerous transformation, and treatment. Stress is laid on the importance of optic fibre endoscopy in diagnosis and therapy (by means of the surgical fibroscope). Examination of the literature, it is felt, substantiates the need for: 1) routine systematic investigation of the digestive apparatus in all subjects with FPC and GS, and the report of even isolated cases to establish the true frequency of the association; 2) histological assessment of radically resected formations in the correct determination of both diagnosis and prognosis; 3) preventive and systematic endoscopic control as a means of investigation and postoperative surveillance; 4) correct strategy based on the nature, extent, number and size of the polyps and the polypogenetic capacity of the gastric mucosa.

Colonic Neoplasms↗

PubMed1968