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Results for “ANTHRACOSILICOSIS”

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At least 19 recordsLinked to original sources

PubMed1989

[An comparative analysis of the radiographic appearances and the pathologic findings in anthracosilicosis and anthracosilicosis associated with tuberculosis].

Pulmonary tuberculosis is a serious complication of anthracosilicosis and a promoting factor for death. It is very difficult to distinguish the advanced stage of atypical anthracosilicosis from anthracosilicosis associated with tuberculosis by the chest radiograph when the tubercule bacili is negative in sputum, but it is necessary for physician to treat and administrate. In order to probe into the differential diagnosis of these two diseases author made a comparison analysis between the radiographic appearances and the pathological findings of 21 autopsies cases which were clinically diagnosed as anthracosilicosis associated with tuberculosis. There were 8/21 cases (38.1%) of misdiagnosis before the misdiagnosis there were the lack of series observation on the similarities and differences in radiographic appearances between these two diseases and neglect of sputum examination. The main points of clinical differentiation between them were summed up.

Adult↗

PubMed1978

[The concurrence of bronchial carcinoma and anthracosilicosis in the lung (concomitantly a contribution to "silicotic carcinoma in scar tissue of the lung")].

Among 4608 evaluated post mortem records (3452 miners with silicosis and 1156 miners without silicosis or nonminers resp.) 501 cases had developed a bronchial carcinoma. 425 of these observed cases showed a bronchial carcinoma together with silicosis, 76 cases were without anthracosilicosis. The occurrence of the bronchial carcinoma in case of anthracosilicosis did not depend on the time of employment in the underground mining industry. Neither was there a correlation between the determined grade of anthracosilicosis and the frequency of bronchial carcinoma. The diagnosis for 2,8% of these combined cases of anthracosilicosis and bronchial carcinoma was silicotic carcinoma of scar tissue. Statistically no signficant differences could be detected between the two groups of bronchial carcinomata with and without silicosis regarding age structure, kind of propagation and histological type of the bronchial carcinoma.

Aged↗

PubMed2001

[Comparative analysis of respiratory function in miners suffering from anthracosilicosis and silicosis].

The authors revealed differences in pulmonary volumes, bronchial patency of bronchi at various levels, integral time of air transit in individuals having early anthracosilicosis and silicosis signs vs in healthy miners. During stage 1 of anthracosilicosis and silicosis respiratory function progressively deteriorates and demonstrates moderate disorders. When compared to anthracosilicosis ones, patients having polymetallic dust silicosis showed more significant decrease of the studied parameters.

Anthracosilicosis↗

PubMed1986

Granulomatous involvement of the liver in anthracosilicosis.

The authors reexamined 300 autopsies which were carried out from 1965 to 1983, on male subjects affected by pulmonary anthracosilicosis already diagnosed in vita and holders of pensions for invalidity allocated to them by the Istituto Nazionale Assicurazione Infortuni sul Lavoro. Their livers were reexamined and the specimens which contained agglomerates of at least 5 macrophages in phagocytic activity with dust particles and birefringent silica crystals were considered positive for a silicotic interstitial type involvement of the organ. Larger accumulations of macrophages in fibroelastic activity, including those with fibrohyaline evolution, were considered as silicotic granulomas. Only the incidence of the hepatic granulomatous types was analyzed and related to the severity of the disease, classified according to four types of increasing gravity: interstitial, nodular, confluent and massive. The statistical analysis of the data demonstrates that there is a close correlation between the gravity of pulmonary anthracosilicosis and hepatic involvement, less in interstitial and more in massive types; thus, it is dependent on the amount of silica. On the other hand, the granulomatous evolution following hepatic involvement is not correlated with the gravity of pulmonary anthracosilicosis; therefore, it is not dependent on the amount of silica but is an individual cellular response.

Anthracosilicosis↗

PubMed1999

[Parameters of oxidative metabolism, neuro-humoral and hormonal regulation in the condensed exhaled air in early stages of anthracosilicosis].

For early diagnosis of anthracosilicosis, the authors studied oxidation parameters, neuromediators and hormones in expired air condensate in coal miners. Premorbid stage of anthracosilicosis is characterized by activated lipids peroxidation, high levels of neuromediators (acetylcholine, catecholamines), tissue hormones (histamine, serotonine) and lower contents of adaptive hormones (cortisol, triiodothyronine, thyroxine).

Air↗

PubMed1990

[Cytochemical indices in initial manifestations of anthracosilicosis].

57 coal miners aged 40-58 years were examined in three groups. Group 1 included 12 practically healthy miners who no contact with industrial dusts. Group 2 consisted of 15 healthy miners (index O) and Group 3-30 miners affected with anthracosilicosis (index 0-1). The phagocytic activities of the alveolar neutrophils and macrophages were studied along with that of the peripheral blood neutrophils. Cytochemical techniques were applied to study the content of general protein, phospholipids, glycogen and the acid phosphatase activity. In Group 2, cellular reactions were marked by a relative content growth of neutrophils and macrophages, and viable cells, against a statistically reliable increase of acid phosphatase activity and phospholipids' content, with concomitant decrease in content of general protein and glycogen. The studies helped to reveal the latent forms of anthracosilicosis at early stages, when morphologic changes could not be traced with ordinary X-ray techniques.

Adult↗

PubMed1980

[Morphology of the liver in anthracosilicosis (author's transl)].

Histological sections of the liver taken at the autopsy of 26 patients with anthracosilicosis of different degrees of severity were investigated retrospectively. Single macrophages containing dust were found in the portal fields, as well as dust storing Kupfer cells proliferating centroacinarity. Granuloma of the walls of central and sublobular veins could be observed, containing infiltrates of lymphocytes and plasma cells, proliferating fibroblasts including histiocytes, and fibrosis and hyalinisation in later stages. It may be assumed, that dust pigments are being transported by blood and taken up by Kupler cells in the first line, to be transmitted directly to the central vein and to a lesser degree by way of lymph drainage into the portal mesenchyma in a later stage. These morphological changes of the liver apparently did not cause any clinical symptoms; they could be found in a high percentage of all patients, which did not have cirrhosis of the liver, and they could be found in all degrees of severity of anthracosilicosis. Thus liver biopsy will yield valuable diagnostic results in this granulomatous disease of the liver as well.

Anthracosilicosis↗

PubMed1964