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At least 19 recordsLinked to original sources

Radiographically guided needle biopsy of abdominal neoplasms--who, how, where, why?

Radiographically guided percutaneous needle biopsy is a safe, accurate, well-tolerated alternative to laparotomy for confirmation of advanced abdominal malignancy. Here we describe the indications and methodology for its performance. Eighty-two percent of 66 patients with proven abdominal neoplasms were successfully biopsied with a fine-caliber needle using a variety of guidance methods. Cross-sectional techniques, such as ultrasound and computed body tomography (CBT), provide the preferred monitoring techniques because of their excellent soft-tissue resolution and the capacity to determine tumor depth accurately. The ability of CBT to define the exact position of the biopsy needle tip in a mass makes it the preferable guide for biopsing of small, solid lesions.

Abdominal Neoplasms

Using celioscopy to determine stages of intra-abdominal malignant neoplasms.

From January 1973 through June 1974, 23 patients underwent celloscopy to assess the extent of intra-abdominal malignancy. Of the 23 patients in the study, eight were spared a needless exploratory procedure. Three patients had potentially curative surgery after intrahepatic neoplasm suggested by liver scintiscan was excluded by celloscopy. The therapies of eight patients were greatly altered after the extent of hepatic or peritoneal disease was de-ermined. Four patients had no change in treatment as a result of celloscopy. Three additional patients underwent celloscopy to determine the cause of an intra-abdominal mass. No complications occurred in these patients. We conclude that celloscopy prior to a major operative procedure may assist in determining the stage of intra-abdominal malignant disease and may lead to notable changes in patient management.

Abdominal Neoplasms

Cavography in the management of malignant abdominal tumors.

Six cases of malignant abdominal neoplasm with extensive tumor involvement of the veins form the basis of this report. One case was a child with retroperitoneal liposarcoma. Proper therapeutic management in these cases was dependent upon a complete angiographic evaluation, including cavography. This procedure is virtually without complications and should, therefore, be done routinely in cases of abdominal neoplasms for evaluation of the operability, to confirm the angiographic findings indicating intravenous tumor invasion or extravenous compression, and as a primary examination in the assessment of possible or known abdominal tumors in children.

Abdominal Neoplasms

Gallium-67 imaging in abdominal disease.

Gallium-67 imaging is useful for detecting sites of intra-abdominal inflammation, including subphrenic abscesses, postoperative infection, pyelonephritis or perinephric abscesses, and peritonitis. Positive images may be obtained within several hours of injection, but are more reliable at 24 hr. The results may be used to guide ultrasound or computed tomography studies, which give a detailed anatomic picture of the abscess. Gallium-67 imaging has also been used to detect abdominal neoplasms, but results are less impressive. Abdominal lymphoma is detected in just over 50% of sites. Gastrointestinal, renal, and gynecologic neoplasms are detected even less frequently. However, 67Ga is useful for detecting recurrence of 67Ga-avid neoplasms, and has been reliable in detecting hepatomas and nodal spread of seminoma. When used selectively in patients with neoplastic disease and suspected abscesses, 67Ga is an effective method for diagnosing abdominal disease.

Abdomen

Continuing experience with palliative chemical splanchnicectomy.

Forty-one patients underwent open phenol splanchnicectomy for control of pain at the time of initial laparotomy for what was thought to be unresectable pancreatic carcinoma. Twenty-three patients underwent concomitant biliary and/or intestinal bypass procedures. In no patient was laparotomy performed only for the purpose of performing splanchnicectomy. The operative mortality was 15%. In no patient could the addition of splanchnicectomy be implicated as the cause of death. Eighty-eight per cent of patients experienced relief of pain postoperatively. The mean duration of pain control was 4.3 months. The mean postoperative survival was five months. No postoperative complications could be attributed to the addition of splanchnicectomy. Open phenol splanchnicectomy is a highly successful and safe ancillary procedure for control of pain and is recommended at the time of initial laparotomy in patients found to have advanced intra-abdominal neoplasm.

Abdominal Neoplasms

Chronic mesenteric ischemia masquerading as cancer.

Mesenteric vascular insufficiency should be suspected in patients with a history of abdominal pain, marked weight loss and significant atherosclerosis. Selective mesenteric angiography is essential and should be used early in the work-up studies of such patients. To ensure clinical correlation, there should be significant occlusion demonstrated in two of the three major mesenteric arteries. Four patients studied extensively for an intra-abdominal neoplasm had occlusive disease of the mesenteric artery demonstrated by arteriography. Elective surgical revascularization of the intestine successfully corrected the problem.

Abdominal Neoplasms

Computed tomography of the body: initial clinical trial with the EMI prototype.

A review of the first 400 cases examined on one of three prototype EMI body scanners is presented. During the initial evaluation phases, it became obvious that computed tomography of the body has tremendous potential in the evaluation of various organs and disease states. The technique has been most useful in evaluating patients with known or suspected abdominal neoplasm, particularly lesions of liver, pancreas, retroperitoneum, and kidney. Too few cases have been studied to realistically quantitate its impact on the total field of medical diagnostic imaging.

Abdominal Neoplasms

Transcatheter brush biopsy of intravenous tumor thrombi.

Transcatheter brush biopsy of intraluminal filling defects demonstrated during venography was performed in 6 patients with abdominal neoplasms. Tissue specimens consistent with either known or subsequently proved tumor were obtained from 4 patients. Biopsy was negative in the other 2 patients, who lacked surgical confirmation of the intraluminal mass. This technique is useful in establishing histological proof of neoplasm and in determining the extent of known tumor.

Abdominal Neoplasms

The modification of gastrointestinal tolerance and responses to abdominal irradiation by chemotherapeutic agents.

Groups of male DBA/2 mice were irradiated with partial abdominal exposures of x radiation ranging from 100 to 1,600 rads. Concomitant with radiation exposure and at 1 or 4 hours prior to, and at 1, 6, 24, or 48 hours after irradiation, various chemotherapeutic agents were administered, i.e., methotrexate, Cytoxan, adriamycin and BCNU. The results suggest that excessive gastrointestinal toxicity may result if aggressive chemotherapy is closely spaced with radiation exposure for the treatment of abdominal neoplasms. However, adjustment of dose and time patterns based on the proliferative responses of the mucosa may circumvent such toxicity to a large extent.

Animals

[Plain abdominal film in neoplasms of the large bowel. - A comparative study with a population of normal subjects (author's transl)].

A comparative study was performed between plain abdominal films of 110 patients with neoplasms of the large bowel and 52 normal subjects for control. In neoplasms of the right colon the failed spontaneous visualization of caecum and ascendent colon or the direct recognization of lume's deformation allow us to suspect such a lesions in about 90% of the cases. Neoplasms of the other tracts of the large bowel may be suspected only when plain abdominal film demonstrates direct evidence of an obstruction: in about 25% of the cases.

Adult