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Results for “Adenoma, Chromophobe”

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At least 19 recordsLinked to original sources
PubMed1976

[Endocrinological evaluation of seller and suprasellar tumor cases (the third report)-on secreting chromophobe adenoma (author's transl)].

1) Nine of 25 cases of chromophobe adenoma revealed abnormally high plasma prolactin level. The plasma prolactin level of these 9 cases ranged from 5300 to 15000 ng/ml, and those of other 16 cases ranged from negligible to 53 ng/ml. 2) Five cases with abnormally high plasma prolactin level had a poor clinical course. 3) Quantitative determination on PEG according to our own method showed that tumor size of these patients with abnormally high plasma prolactin level was larger than that of relatively lower plasma prolactin level. 4) Three of all 25 cases of chromophobe adenoma were histologically diagnosed as pleomorphic. Each of those three cases showed abnormally high plasma prolactin level.

Adenoma, Chromophobe↗
PubMed1977

An unusual case of chromophobe adenoma with conspicuous calcifications.

Abnormal calcification on skull films in the region of the sella turcica is not commonly found with chromophobe adenoma. A patient with such calcification in a verified chromophobe adenoma is presented. From the literature the incidence of calcification in these tumours is reviewed. The importance of considering a chromophobe adenoma in the differential diagnosis of parasellar calcification from the surgical point of view is mentioned.

Adenoma, Chromophobe↗
PubMed1976

Third ventricular chromophobe adenoma with normal adenohypophysis.

An unusual case of chromophobe adenoma occurring in the third ventricle is reported. Ventriculography revealed a filling defect in the third ventricle and at autopsy the tumour was found in the posterior part of the third ventricle. No tumour was detected in the pituitary gland.

Adenoma, Chromophobe↗
PubMed1978

Cytoplasmic filamentous masses in chromophobe adenoma of the human pituitary gland.

The fine structure of filamentous masses in three cases of chromophobe adenoma of the pituitary gland is reported. These three were among 18 cases of chromophobe adenoma, 13 non-functioning and five with acromegaly, studied by electron microscopy. All the three cases with fine filamentous masses were adenomas with acromegaly and none of the non-functioning adenomas showed these structures. The cells containing filamentous masses were rich in rough endoplasmic reticulum and poor in secretory granules. These masses were composed of fine filaments and, in some, tubular structures and granules were also present. Prominent RER and sometimes an extensive Golgi system was seen in the adjacent cytoplasm. It is suggested that the filamentous masses arise as a result of degeneration and disintegration of RER and Golgi apparatus.

Acromegaly↗
PubMed1978

Malignant pituitary chromophobe adenoma in an infant accompanying diabetes insipidus.

This report deals with a 1.5-year-old male infant terminating in viral pneumonia and "diabetes insipidus". The autopsy revealed malignant pituitary chromophobe adenoma, invading the wall of the third ventricle, extending to the periventricular-, dorsomedial- and ventromedial area, skipping to the lateral area adjacent to the optic nerve, and permeating into the subarachnoid space of the cerebrum. At the onset of disease polydypsia and polyuria were marked followed by interstitial pneumonia with high fever, and later generalized tonic convulsion terminated in death. This case is peculiar in at least two respects. Firstly, this is the youngest reported case of malignant chromophobe adenoma. Secondly, the manifestation of diabetes insipidus is rare in chromophobe adenoma. The malignant adenoma probably occurred from the primitive gland rest of chromophobe cells in the posterior lobe becoming malignant during the course of growth development and destroyed the cells of the posterior lobe, resulting in diabetes insipidus.

Adenoma, Chromophobe↗
PubMed1977

Galactorrhea in a 12-year-old boy with a chromophobe adenoma.

A 12-year-old with galactorrhea is presented. He was in early puberty, had gynecomastia, and was markedly obese. Roentgenograms of the skull showed an asymmetrically enlarged sella trucica, but pneumoencephalography did not indicate suprasellar extension of the pituitary tumor. Preoperative studies of anterior pituitary function were normal except for persistent hyperprolactinemia. By transsphenoidal approach, a microadenoma of the pituitary was removed. Lactation ceased within a week, and four months postoperatively the patient had normal anterior pituitary function studies. A review of the literature indicates that galactorrhea in males is very rare. The most frequently documented cause, excluding drug ingestion, is a pituitary tumor.

Adenoma, Chromophobe↗