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At least 19 recordsLinked to original sources
PubMed1979

[Prediction of anemia or polycytosis from the hematocrit determination in the umbilical artery of the newborn (author's transl)].

Among 430 deliveries a random group of 100 newborns were used to determine the value of the umbilical arterial hematocrit for the prediction of neonatal anemia or polycytosis. Normal values were Hct, 48 vol.% to 72%. Even considering the PH of umbilical arterial blood, the Hct. in the umbilical attery permits an excellent prediction on the neonatal Hct. at 15 to 60 minutes post-partum. When the umbilical arterial Hct. is normal a capillary Hct. determination is not necessary for routine diagnosis. If the umbilical arterial Hct. is below 46% or above 61% a capillary Hct. is necessary since below 46% or above 61% neonatal anemia or polycytosis could be found.

Anemia, Neonatal↗
PubMed1979

Sickle cell anemia in the neonatal period.

Although sickle cell anemia rarely presents with clinical manifestations in the newborn period, it should be considered a possible cause of unexplained early jaundice in black newborn infants. If sickle cell disease is suspected, sickle cell preparation and hemoglobin electrophoresis of the infant and of both parents should be carried out.

Anemia, Sickle Cell↗
PubMed1977

Experimentally induced anaplasmosis in neonatal isohemolytic anemia-recovered calves.

Anaplasma marginale infections were induced in 3 calves previously affected with neonatal immunohemolytic anemia (NIA). Similar infections were induced in 6 splenectomized and 7 intact calves. The response to infection by 3 calves (NIA recovered) closely resembled infections seen in splenectomized calves, being markedly more severe than similar infections in intact calves. Spleens from 3 (NIA recovered) calves after splenectomy were about one-tenth normal size. Marked recrudescing anaplasmal infections were not detected after splenectomy of the calves (NIA recovered), whereas marked recrudescing infections were observed after splenectomy of 2 intact calves having recovered from the primary infections.

Anaplasmosis↗
PubMed1976

Cerebral distress in full-term newborns and its prognostic value. A follow-up study of 90 infants.

The history of 90 full-term infants with neonatal cerebral distress was examined. Informations concerning pregnancy, delivery, neonatal status, clinical and laboratory evolution were compared with final outcome in each case. It was then possible to distinguish certain clinical features significantly associated with poor prognosis. After statistical analysis, different adverse criteria were selected, such as severe neonatal asphyxia, associated respiratory disorders, acute anemia, and especially neurological signs with regard to their chronology. This part of the study has resulted in a classification of the neurological signs and has permitted the description of both malignant and benign cerebral distress syndromes.

Anemia, Neonatal↗
PubMed1978

Microangiopathic hemolytic anemia and thrombocytopenia in a neonate associated with a large placental chorioangioma.

The case of an infant born in association with a large chorioangioma of the placenta is presented. The maternal complications of polyhydramnios, preeclampsia, and premature labor are those described in the "syndrome" of a chorioangioma. The immediate neonatal course was unusually complicated by severe microangiopathic anemia with persistent thrombocytopenia and hemolysis which required three exchange blood transfusions. The relationship between the neonatal complications and the placental tumor is discussed in terms of possible pathophysiologic mechanisms.

Anemia, Hemolytic, Congenital↗
PubMed1992

Characterization and developmental expression of binding sites for the transplacental iron transport protein, uteroferrin, in fetal hematopoietic tissues.

In the pig, iron transport to the developing fetus during pregnancy involves, in part, uteroferrin (UF), a secreted progesterone-induced protein of the uterus. Neonatal pigs suffer from anemia, and the decrease in the synthesis of UF protein in late pregnancy was suggested to be partly responsible for this condition. To examine whether diminished capacity for UF uptake by pig fetuses may also contribute to neonatal anemia, binding sites for 125I-UF were examined in plasma membrane-enriched fractions of fetal liver and spleen, which are sites of fetal hematopoiesis. In addition, changes in the number of these binding sites as a function of fetal development were evaluated. Binding of 125I-UF to liver membrane fractions was displaced by intact UF greater than deglycosylated (aglyco) UF greater than ovalbumin, but not by yeast mannan. Scatchard analysis of radioligand binding showed the presence of a single class of binding sites with a dissociation constant of 10(-7) M. During fetal development and at postpartum (day 5), liver binding sites for UF remained invariant and displayed the same affinity. In contrast, the number of binding sites for UF in fetal spleen increased from midpregnancy to parturition and remained elevated in day 5 neonatal spleen. Affinity cross-linking of 125I-UF to liver membrane-associated binding sites and subsequent analysis by gel electrophoresis and autoradiography demonstrated a single labeled protein complex of Mr 58,000 and 87,000 under denaturing and nondenaturing conditions, respectively. The appearance of these bands was inhibited by intact UF, but not ovalbumin. The characteristics of the membrane-associated binding sites for UF differed from those of the mannose-related receptor previously described in reticuloendothelial cells of fetal liver. The invariant presence of UF binding components in sites of hematopoiesis during fetal development suggests that mechanism(s) unrelated to specific uptake of UF are responsible for neonatal anemia.

Acid Phosphatase↗
PubMed1992

[Severe form of neonatal hemolytic disease by anti-Vel allo-immunization].

BACKGROUND: Routine detection of maternal sensitization during pregnancy sometimes reveals alloimmunization by exceptional antigens. CASE REPORT: A first pregnancy was complicated by a severe post-partum anemia in the mother, that required a blood transfusion. Irregular agglutinins were detected during the first trimester of a second pregnancy, for which the father was different from the first. The specific antibody was not identified at that time. The newborn, born at a gestational age of 39 weeks, developed severe jaundice at 3 hours of life, with hemolytic disease, anemia and hepatomegaly. Therapy included two transfusions of packed, washed red cells obtained from the mother on days 7 and 25. Immunologic tests showed that the hemolytic disease of this newborn was due to an anti-Vel alloimmunization. CONCLUSION: Antibodies detected during the pregnancy must be identified in order to manage properly any perinatal problems due to rare antibodies.

Anemia, Hemolytic↗
PubMedDate not supplied

Packed cell volume reference intervals to aid in the diagnosis of anemia and polycythemia in young leghorn chickens.

Packed cell volume (PCV) reference intervals were established for use in diagnosing anemia and polycythemia in young chickens. Blood samples were collected from 3-to-35-day-old specific-pathogen-free leghorn chicks. PCVs were determined and analyzed. PCVs regressed significantly (P less than 0.0001) on age, which shows that neonatal physiologic anemia occurs in chicks as well as in mammals. The definition for anemia in chicks varies with age. We defined anemia as a PCV less than or equal to 23%, 25%, 26%, 28%, 31%, and 30%, respectively, for chicks 3, 7, 14, 21, 28 and 35 days old. We defined polycythemia as a PCV greater than or equal to 36%, 37%, 38%, 37%, 41%, and 40%, respectively, for chicks 3, 7, 14, 21, 28, and 35 days old. Healthy chicks have PCVs within established reference intervals. Results provide guidelines to detect anemia and polycythemia in young leghorn chicks of various ages.

Anemia↗
PubMedDate not supplied

Packed cell volume reference intervals to aid in the diagnosis of anemia and polycythemia in young broiler chickens.

Packed cell volume (PCV) reference intervals were established for use in diagnosing anemia and polycythemia in young broiler chickens. Blood samples were collected from one hundred twenty 3-to-49-day-old clinically healthy conventionally reared broiler chickens. PCVs were determined and analyzed. PCVs regressed significantly (P less than 0.025) on age, which shows that neonatal physiologic anemia occurs in broiler chickens, as well as in mammals and specific-pathogen-free (SPF) chickens. The definition for anemia in broiler chicks varies with age. We defined anemia as a PCV less than or equal to 26%, 29%, 33%, 32%, 33%, 33%, 31%, and 28% for broiler chickens, 3, 7, 14, 21, 28, 35, 42, and 49 days old, respectively. We define polycythemia as a PCV greater than or equal to 42%, 43%, 41%, 40%, 42%, 42%, 41%, and 40% for broiler chickens 3, 7, 14, 21, 28, 35, 42, and 49 days old, respectively. Otherwise, broiler chickens have PCVs within established reference intervals. Results provide guidelines for detecting anemia and polycythemia in young broiler chickens of various ages.

Analysis of Variance↗
PubMed1976

[Congenital cytomegalovirus infection after maternal renal transplantation (author's transl)].

A 34-year-old female gave birth to a 32 to 35 week-old girl one year after she had undergone renal transplantation. The child was dwarfed and microcephalic and also had congenital platelet deficiency and purpura. In addition it was anaemic and suffered from severe neonatal icterus. An initial hypogammaglobulinaemia disappeared except for low IgA levels. The immunoglobulin deficiency is probably correlated with the virologically and serologically proven cytomegalovirus infection. The incidence of this disease seems to be high in children of mothers with renal transplantations.

Agammaglobulinemia↗