PubMed HealthSearch

SEARCH · PubMed Health

Results for “Ascariasis”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 19 recordsLinked to original sources

Malabsorption of water miscible vitamin A in children with giardiasis and ascariasis.

Vitamin A absorption was studied using a water-miscible oral preparation of vitamin A in 19 children ages 1 1/2 to 9 years old with giardiasis and/or ascariasis, both before and after their eradication with appropriate therapy, and in three children without parasites. Marked impairment of vitamin A absorption was noted when administered in a water miscible form in children with 1) combined infection with Giardia lamblia and Ascaris lumbricoides, 2) giardiasis alone, and 3) in a proportion of children with ascariasis alone. In children with both giardiasis and ascarasis eradication of the infections promptly lead to a significant improvement in vitamin A absorption and restored it to normal. Children with giardiasis alone also showed improved vitamin A absorption after therapy. In children with ascariasis alone successful therpay did not lead to a statistically significant improvement.

Ascariasis

Ascariasis and malnutrition. A study in urban Ethiopian children.

Treatment of 13 urban Ethiopian children with mild ascariasis did not produce any evidence of improved intestinal morphology and absorption or nutritional status. Ascariasis treatment had no impact on anthropometric measures in an additional study group of 84 children. A review of the literature reveals that the nutritional consequences of ascariasis are uncertain.

Anthropometry

Levamisole in ascariasis. A multicenter controlled evaluation.

An analysis is presented of 10 clinical studies from various countries where levamisole 50--150 mg was compared to pyrantel, piperazine, and placebo in a total of 1,734 patients, mostly children (levamisole: 830, controls: 904), suffering from ascariasis either as a single infection or usually mixed with other nematode infections. Degree of infection and efficacy of treatment were determined by quantitative coproparasitological methods. Levamisole produced higher cure rates (91%) and egg reduction rates (98%) than pyrantel, piperazine, or placebo. The efficacy of levamisole was unrelated to the patients' sex and age, the severity of infection, the presence of another worm infection, the type of associated worm infections, or the egg-counting technique. The overall incidence of reported adverse reactions was lower after levamisole than after piperazine, pyrantel or placebo; abdominal pain and headache, the most frequent complaints after levamisole, were related to the initial severity of ascariasis. Follow-up examinations 6 months after treatment suggested that levamisole might delay reinfection.

Adolescent

Pulmonary ascariasis.

A case of pulmonary ascariasis is reported for the first time in Australia. Because of increasing immigration from countries which have a high incidence of ascariasis (especially those of South-East Asia), and increasing travel to Asian countries, the awareness of this infestation as a cause of respiratory disease may be of great importance.

Ascariasis

Mass control of ascariasis with single oral doses of levamisole. A controlled comparison in 3,056 subjects between three incomplete population coverages.

Ninety-, 60-, and 40-percent population coverages with levamisole 2.5 mg/kg of body weight were compared for their effects on Ascaris lumbricoides, ancylostoma, Strongyloides stercoralis, and Trichuris trichiura infections. They were shown to be effective in maintaining a reduced prevalence of A. lumbricoides in the treated subjects for 9, 6, and 3 months, respectively. Nine months after treatment, the prevalence of ascariasis was still lower than before treatment both in the levamisole and in the control subjects, regardless of the population coverage. This was probably because the egg output had been reduced. It is concluded that mass treatment with single oral doses of levamisole repeated at 3-month intervals might help control ascariasis, and that population coverages between 60 and 90% might be appropriate. No clear-cut effects against hookworms could be shown, possibly because the first follow-up examinations were performed three months after treatment. No changes in the prevalence of S. stercoralis and T. trichiura could be demonstrated. There were no adverse exp

Administration, Oral

Clinical trial of levamisole in the treatment of ascariasis in Khorasan, Iran.

This paper identifies the parasitic infections and their incidence in 246 people aged between 10--20 years living in a semi-rural Iranian village. 64 patients with ascariasis were treated with levamisole ('Ketrax' ICI) in accordance with the manufacturer's instructions. Most were followed up 1 and 2 weeks after treatment, with cure rate of 97.7% and 98.4% respectively, as assessed by negative egg findings in faeces. No side effects were reported. Levamisole meets the requirements of individual and mass treatment of ascariasis.

Adolescent

Ascariasis of the gastrointestinal tract.

The radiographic findings and complications of Ascaris lumbricoides infection of the gastrointestinal tract are presented. Since the clinical symptoms of ascariasis are usually vague or nonspecific, the radiologist may be in a position to play a major role in the proper diagnosis of this disease.

Ascariasis

Intestinal perforation in ascariasis--case reports.

Two cases of intestinal perforation in association with ascariasis are described. In both cases adult ascarids were found either in the gut or lying free in the peritoneal cavity. Neither patient had typhoid fever, one had Hodgkin's lymphoma. The authors believe that the perforation were directly caused by the ascarids. Both patients died.

Adult

Ascariasis--its complications, unusual presentations and surgical approaches.

Serious complications of ascariasis are varied and occur at all stages of worm development. The acute condition within the abdomen heralds the presence of intestinal, pancreatic, or biliary tract obstruction secondary to the physical presence of the adult parasites. Larvae may be responsible for acute respiratory disease, either as a direct allergic phenomenon or as a pneumonic infiltrative process secondary to fellow traveler bacteria. Deposition of ova in the liver allows for intrahepatic and pericholangitic abscesses with resultant parenchymal destruction and scarring. Though primary therapy is medical, specific indications for surgical intervention are discussed. These unusual but life-threatening sequelae are typified in the case presentation of a critically ill child.

Ascariasis

Biliary ascariasis.

The presenting clinical features of a series of cases of biliary tract ascariasis are described, in particular the characteristic colicky pain which occurs. The term 'ascaritic biliary pain' is introduced for the symptom diagnostic of live Ascaris adult worms inside the biliary passages. Methods of diagnosis before, and in the course of, operation are discussed and seem adequate. The management of worms discovered in the bile ducts, and those in the proximal small bowel, is described.

Adult

Biliary ascariasis in children.

The ascaris is a common human parasite and has a world wide distribution. In areas where it is endemic, biliary complications are common. In our locality it occurs mainly in children, presenting with upper abdominal colicky pain usually without jaundice. We have analyzed the positive roentgenological findings of 67 cases which presented in one year. The findings on cholangiography are diagnostic. The worm is seen as a linear translucent filling defect in a dilated common bile duct. Usually it is only faintly outlined by thin tram lines and occasionally there may not be excretion of the contrast material. The attention of radiologists is brought to this condition and the appearances of ascariasis infestation of the intestines are also noted.

Age Factors

[Surgical complications of ascariasis and their treatment].

548 cases of abdominal complications of ascariasis such as intestinal ileus--208 (37.9%), perforation of the intestinal wall and postoperative complications--35 (6.4%), appendicitis--26 (4.8%), gastrointestinal bleedings--11 (2%), lesions of the bile passages, liver and pancreas--25 (4.6%) and pseudoabdominal syndrome--243 (44.3%), have been analysed. Consideration has been given to the peculiarities of the diagnosis and treatment. The total lethality constituted 4.4%. The highest fatality occurs in case of the lesions of the hepatobiliary system and destructive injuries to hollow organs.

Acute Disease

Biliary ascariasis--endoscopic aspects. Report of 4 cases.

Retrograde cholangiography was carried out in 4 small children with suspected roundworm infestation of the biliary tree. An adult-sized side-viewing fibre-optic duodenoscope was employed, and a general anaesthetic was given in each case. Roundworms were frequently seen protruding from the papillary orifice when biliary infestation was present. Cannulation of the duodenal papilla was shown to be eminently feasible in these small children, whose average weight was 12,4 kg. The degree of infestation and the response to vermifuge therapy could be determined with precision by retrograde cholangiography. It is suggested that this procedure has a place in the management of the complicated case of biliary ascariasis, and that it should certainly be considered when surgery is contemplated.

Ascariasis

[Comparison of the sensitivity of complement-fixation test and latex-fixation test in the demonstration of a migration phase of ascariasis (Ascaris suum) in a non-specific host].

The authors compared the sensitiveness of the complement-fixation reaction and the latex-fixation test in the demonstration of a migration phase of ascariasis in a non-specific host (rabbit). The sensitiveness of the latex-fixation test was higher by the value of one dilution of the geometric series, on an average.

Animals

Ascariasis of the gall bladder. Report of two cases.

A radiological diagnosis of ascariasis of the gallbladder was made in two middle-aged women with high abdominal pain having biliary colic characteristics. In one case round worm was demonstrated by means of the intravenous cholangiography, but in the other the procedure was negative only the common bile duct being contrasted. Oral cholangiography made some days later permitted the visualization of the parasite in the gallbladder. The patients were treated by cholecistectomy and choledocostomy and the diagnosis was confirmed. The post-operative course was uneventful. There was Ascaris lumbricoides ova in the feces and the histological examination of the removed gallbladder showed large eosinophilic infiltration in both cases. The patients received levamisole some days after surgery.

Adult

[Effectiveness of antigens from various developmental stages of Ascaris suum in the deomonstration of the migratory phase of experimental ascariasis in pigs].

Tests of the efficiency of antigens prepared from different developmental stages of Ascaris suum in indirect haemagglutination test in the course of proving the migration phase of experimental ascariasis in pigs show that the antigens prepared by ultrasound from the invasive larval stage of A. suum in comparison with antigens of sexually mature stages have higher serological activity. By using this antigen it is possible to prove specific antibodies in experimentally invaded pigs from 6 to 120 days after invasion as opposed to the other tested antigens (the detectability of antibodies from the 7th-8th day to the 64th day after invasion).

Animals

[Comparison of the sensitivity of the passive, indirect hemagglutination reaction and the latex fixation test in the demonstration of the migratory phase of experimental ascariasis (Ascaris suum) in swine].

The authoresses verified diagnostic sensitivity of two serological tests -passive indirect hemagglutination [IHA] reaction modified by the authoresses and latex-fixation test [LFT] when proving the post-invasion migratory phase of ascariasis [Ascaris suum] in experimentally infected swine. The IHA reaction was found to be more sensitive than the LFT in most cases [62.2%] by two to three values of the geometric series. The invasion can be detected by the IHA reaction from 7th to 120th day and by the LFT from 7th to 49th day after invasion.

Animals