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[The state of development of interventional cardiology in Austria].

3,157 PTCA were performed in Austria in 1991, this is 27% more compared to 1990. Prognosis for 1992 is another 27 to 30% more. Frequency of PTCA exceeded bypass surgery in 1990 for the first time in Austria. WHO-guidelines of 1,000 interventions per year and 1 million inhabitants will be achieved in Austria by 50% in 1992. In this context it is worth while to state, that installation of further cathlabs is recommended preferably within established centers including established heart surgery. The following NON-POBA-PTCA-techniques ("New devices") were used in Austria for the first time: Atherectomy, stent, lasers, TEC, ROTABLATOR, ROTACS, magnum wire and angioscopy accounted for 11.3% of all PTCA cases in Austria recently. A total of 447 valvuloplasties were performed in Austria until now, frequency of pulmonary and mitral valvuloplasties is increasing, that of aortic valve interventions decreasing. High frequency, Radiofrequency and Direct current Ablations of supraventricular- and ventricular- or WPW-arrhythmias were performed in 184 patients in Austria until now. In 247 patients with rare conditions, interventions like atrioseptostomy, implantation of umbrellas, etc. were performed. State of interventional cardiology in Austria is appropriate, compared to other European countries.

Angioplasty, Balloon, Coronary

Widespread circulation of Alongshan virus in Austria and serological evidence for infection in humans: a nationwide molecular and serological observational study.

BACKGROUND: Alongshan virus, a segmented RNA virus in the Jingmenvirus group of flaviviruses, was first identified in 2017 in China in patients with tick-borne encephalitis-like illness. Alongshan virus has since been detected in ticks and mammals in several European countries. In this study, we aimed to characterise the temporal and geographical distribution of Alongshan virus in Austria through nationwide tick surveillance combined with serological and molecular screening in individuals with suspected tick-borne encephalitis or tick exposure. METHODS: In this nationwide molecular and serological observational study, we conducted a PCR-based screening of ticks collected across Austria in 2024, using flagging, animal hosts, and citizen submissions. We also collated genomic data from stored nucleic acid extracts from ticks collected in Austria in 2005 and 2013 in previous surveillance studies and stored extracts of paired tick-human samples collected between 2015 and 2018. Alongshan virus-positive tick samples were subjected to whole-genome sequencing and phylogenetic analysis. In addition to tick samples, blood samples from Austrian patients with reported tick bite or suspected tick-borne encephalitis, submitted to the National Reference Center for Human Arbovirus Infections, Austria, were screened for Alongshan virus infection and subjected to serological and molecular testing. FINDINGS: 2952 ticks were collected between Feb 1, 2024, and Dec 6, 2024, from 29 (83%) of 35 NUTS-3 regions in Austria; the median detection rate for Alongshan virus was 1·2% (IQR 0·4-3·5). In addition, 1816 archived tick samples were analysed, with three testing positive for Alongshan virus. For the virus-positive samples, phylogenetic analysis showed that sequences from Austria grouped within the European clade, with Austrian sequences from the same region showing high sequence similarity. 1361 human serum samples collected between March 1, 2023, and May 16, 2025, were assessed for anti-Alongshan virus IgG antibodies. Two individuals had high antibody titres against Alongshan virus proteins VP1a and VP2. INTERPRETATION: Our study shows detection of Alongshan virus in archived tick samples dating back to 2005, representing the earliest documented occurrence of the virus to date and suggesting that Alongshan virus has been circulating in Austria for at least two decades. The detection of Alongshan virus-specific antibody titres in two individuals suggests past infection and previously unrecognised exposure. These results highlight the need for continued molecular surveillance of tick populations and serological monitoring in humans to define the epidemiology and public health relevance of Alongshan virus in Europe. FUNDING: One Health surveillance and Vector monitoring for cross-border pathogens (OH SURVector) and UNITED4Surveillance.

Adolescent

[Maternal mortality in Austria from a clinical point of view].

The maternal mortality rate of 22.4 per 100,000 live births in 1973 is the lowest recorded in Austria. The figures for Austria are compared with the data from other European countries with similar health systems. Austria reflects the overall trend of a decreasing maternal mortality rate. 10 cases of maternal death recorded per 16,447 live births in the 2nd Department of Obstetrics, University of Vienna are presented and discussed with respect to the clinical diagnosis and compared with the main causes of maternal death in the national and international literature. As in other countries, haemorrhage in 3 out of the 10 cases ranks first, whilst in Austria generally, toxaemia has been the most common cause of death in recent years. The main cause of the bleeding is undetected rupture of the uterus, which is frequently concealed behind the clinical diagnosis of circulatory failure with cardiac arrest. 2/3 of the observed cases in the present series are considered to have been avoidable. It is recommended that in future every single reported case of maternal death in Austria is analyzed and the cause of death and the degree of avoidability discussed as is done in England.

Austria

Cost-benefit calculations of vaccinations against measles and mumps in Austria.

The analysis of combined measles-mumps vaccination in Austria showed that this measure is highly profitable in economical respect. The benefit-cost ratio Qc amounts to 2.65 without and 4.48 with consideration of the so-called "nursing vacation", a one week's vacation which is being granted in Austria to employed mothers for the nursing of a sick child once a year. The benefit-cost difference Dc amounts to AS 672.85 OF 1,681.90 respectively, per child. Twelve years after the beginning of vaccination of 100,000 one year old children per year which corresponds roughly to the birth rate in Austria an amount of 63 mill. AS can be saved, if "nursing vacations" are not considered. This amount will be even 528 mill. AS, if "nursing vacations" are taken in account.

Austria

Tobacco-related cancer in relation to prevalence of drinking and smoking in eastern Austria.

Eastern Austrian regional mortality patterns of oral cancer (oral cavity, pharynx and larynx) and oesophageal, lung and urinary bladder cancer were compared to smoker rates and to liver cirrhosis mortality by type of residence: Vienna (1.7 x 10(6) inhabitants), middle towns (50,000-100,000 and 10,000-50,000 inhabitants), small towns (2000-10,000 inhabitants) and rural areas categorized by agrarian quota less than or equal to 10%, 10%-20% and greater than 20%. The study area (Vienna, Lower Austria and Burgenland) covers 23,600 km2 with 3.23 x 10(6) inhabitants. In men, liver cirrhosis correlated negatively with smoker rates (r = 0.74, P = 0.1). Deaths from oral cancer and oesophageal cancer correlated significantly with deaths from liver cirrhosis (r = 0.81, P = 0.03; r = 0.78, P = 0.04, respectively) but not with smoker rates; lung cancer and bladder cancer correlated significantly with smoker rates (r = 0.91, P = 0.01; r0.83, P = 0.04, respectively), but not with liver cirrhosis. In women, similar urban-rural gradients for all parameters resulted in a positive correlation between liver cirrhosis and smoker rates (r = 0.59, P = 0.22) and a significant correlation of lung cancer with liver cirrhosis (r = 0.75, P = 0.05). Oral cancer correlated significantly with liver cirrhosis (r = 0.83, P = 0.02), but not with smoker rates; lung cancer correlated more significantly with smoker rates (r = 0.92, P = 0.01) than with liver cirrhosis; bladder cancer correlated positively with smoker rates (r = 0.70, P = 0.12). Geographical distribution of oral and oesophageal cancer in Eastern Austria seems thus to be highly subject to the prevalence of heavy drinking. Sociocultural influences upon the occurrence of these cancers seem to be mediated through drinking habits rather than through smoking habits alone.

Adolescent

Survey of computerized obstetric information systems in Austria.

The aim of this study was to evaluate obstetric electronic data processing (EDP) in Austria and to analyse its problems, advantages and acceptance in a single big obstetric department. We sent questionnaires to every obstetric department in the country. The overall response rate was 77% (73 departments). Only 24 (33%) were using computer aided documentation, but these covered 63% of deliveries in Austria. The proportionate times spent on documentation were 57% for physicians and 43% for midwives, with physicians playing a bigger role in larger departments using electronic documentation. Sixty-five percent of physicians and 31% of midwives readily accepted computerization. We also studied an obstetric department with over 3000 births per year. Twenty-five percent of the medical staff did not believe that computerization saved time, although they appreciated its value to administration and for producing printouts. Advantages in completeness (92%) and accuracy (76%) were recognized. After 6 month's use acceptance of EDP documentation improved significantly.

Attitude of Health Personnel

[Incidence of coeliac disease in children in Austria (author's transl)].

The incidence of coeliac disease in infants and children was estimated by the number of children born between 1 January 1969 and 31 December 1972 and the number of patients with coeliac disease born during the same period in the area served by the Kinderklinik Graz. The drainage area of the Kinderklinik Graz comprises 10.5% of the population of Austria and 11.1% of the children born in Austria during the period mentioned. The diagnostic criteria for coeliac disease includes evidence of intestinal malabsorption, a subtotal atrophy of the duodenojejunal mucosa and the demonstration of clinical and biochemical response to gluten withdrawal. In all patients born in 1972 a second biopsy was done after a period on gluten free diet and a third biopsy after reintroduction of gluten. The incidence of coeliac disease showed to be 1 in 496. The incidence for girls proved to be 1 in 403 and that for boys 1 in 636. These figures are in good correlation to that reported for Ireland and Switzerland but much higher than those estimated for Britain.

Austria

[Epidemiologic and serologic study of listeriosis in man and domestic and wild animals in Austria].

In the framework of a study aimed to ascertain the possibilities of infection transmission from mother to child the athors examined serologically gravid women for toxoplasmosis and antibodies against listeriosis, using routine methods, in Austria in 1974, 1975 and 1975. Almost all gynecologists of the region of Styria (Austrial), who systematically delivered data concerning abortions, premature births and stillbirths, were invited to take part in the study. At the same time data concerning domestic and wild animals examined for antibodies against listeriosis in Austria in 1974, 1975, 1976 and 1977, were compared.

Animals

[Cost benefit analysis of the program for the improvement of perinatal mortality and morbidity in Austria (author's transl)].

A retrospective cost benefit analysis is initiated for the program to improve the perinatal mortality and morbidity in Austria which was started by the Federal Ministry for Health and Environment in 1974. Based on the official registry of birth in Austria the expenses for the intensive maternity care and delivery are calculated. From 1974-1978 the perinatal mortality of 2,514 children was prevented. It is assumed that for each prevented case of perinatal mortality two cases of cerebral damage were prevented. The benefit is calculated as alternative cost. The comparison of cost and benefit showed an approximate balance.

Austria

Costs and benefits of measles and mumps immunization in Austria.

The usefulness of an immunization programme can be evaluated by comparing either risks and benefits or costs and benefits. By means of special formulae, the benefit-cost ratio and the benefit-cost difference can be calculated for monovalent and bivalent vaccines. An analysis of combined measles-mumps immunization in Austria showed that this measure is highly profitable economically. Since employed mothers are allowed one week's vacation each year to nurse a sick child, this affects the calculations. Including the cost of the "nursing vacation" among the benefits that would be realized following an immunization programme, the estimated benefit-cost ratio is 4.48; if the cost of the "nursing vacation" is omitted the ratio is 2.65. The estimated annual benefit-cost differences are AS 1681.90 and AS 672.85, respectively, per child. Twelve years after the beginning of a programme to immunize 100 000 1-year-old children per year (corresponding roughly to the birth rate in Austria) an amount of AS 528 million would be saved if the "nursing vacation" is included in the calculations and an amount of AS 63 million if it is not.

Austria

[4 years' methadone substitution therapy in Austria].

On September 25th 1987 methadone was legalized for therapeutic use in Austria. During the past four years altogether 1828 opiate addicts were admitted to methadone maintenance treatment. 439 females and 926 males were currently being treated in December 1991; their age ranged from 16-59 years, the daily oral d,l methadone dose levels varied between 10 mg and 250 mg per day. Only 406 doctors and 123 pharmacies participate in methadone maintenance treatment, which does not provide complete cover for the area in spite of increased finding. Moreover, the doctors' skills in this treatment have to be improved by requisite training. As Austrian experience shows, methadone treatment offers a first step towards social rehabilitation for drug addicts who have been living as criminals on the fringe of society. Socioeconomic data, as well as criminal behaviour changed dramatically for the better due to this treatment in Austria. Physicians have a clear responsibility to lead the effort on all fronts in the implementation of this treatment modality. Therapeutic drug monitoring should become routine in methadone treatment to ensure compliance and to achieve optimum results, especially in patients who complain of withdrawal symptoms and continue high-risk behaviour and to increase acceptance of substitution therapy. The Austrian treatment model for methadone maintenance treatment is a positive example for other countries who wish to introduce this treatment modality for drug addiction.

Administration, Oral

[Epidemiology of suicide in Austria 1980 to 1990].

This article investigates the suicide rates in Austria from 1980 to 1990 according to age groups and the methods used. In the years investigated the overall suicide rate increased until 1986, followed by a decline until 1990. The suicide rate in women shows a gradual linear increase with age, whilst in men there is a biphasic curve with a steep increase in teenagers and young men in their early twenties, followed by a plateau and a second steep increase as from 65 years of age, whereby the increase from "60-64 years" to the age group "over 85 years" is 134%. Regarding the age groups the decline over the past years in women is biggest in the groups "35-39 years" and "65-69 years", with men a decrease is present in the age groups from 20 to 50 years. Concerning the methods used, hanging is the most common mode of suicide in both women (36.4%) and men (48.8%). Suicide in the elderly--particularly in old men--which has increased internationally over the past few decades is targeted as the major area for vigorous preventive measures in Austria.

Adolescent

[Perspective in the incidence of Alzheimer's disease in Austria by the year 2050].

Population projections of the Austrian Central Statistical Office show a dramatic increase in the proportion of people of 65 years of age and over in Austria by the year 2050. Since this population group is at higher risk to develop Alzheimer's disease (AD/SDAT), it will be necessary to modify the currently available facilities for social and medical care to meet this increasing demand. Based on official demographic data and epidemiological findings of the "Eurodem" group, our computations show that the number of persons with AD/SDAT aged 65 or over will rise from 48,000 at present to over 113,500 in 2050 (1990: 614/100,000, 2050: 1505/100,000 persons of the total population), equivalent to an increase of 140%. By forecasting the number of persons affected, it should be possible to intensify (and in some areas introduce) long-term health planning with respect to the social, financial and medical care of aged, demented people in Austria.

Aged

[Epidemiology of corpus carcinoma in Austria (author's transl)].

The rates of endometrial carcinoma incidence in Austria were investigated for the period between 1971 and 1975 by the authors in cooperation with the Austrian National Institute of Statistics. The incidence of corpus carcinoma has increased also in Austria over the past decades, as may be seen from the ratio between corpus carcinoma and cervical carcinoma which is 1:1.9 at present. Age related incidence was studied, as well, with continuous growth in incidence having been observed along with growing age. In women aged between 60 and 69, corpus carcinoma was almost as frequent as cervical carcinoma, and it was predominant among women of 70 and above. The findings obtained from age group surveys have also suggested that irradiation therapy rather than primary surgery was required for more than 50 per cent of the patients reviewed.

Adolescent

[Gastroscopy in Austria the results of a questionnaire study (author's transl)].

By means of a questionnaire we have gathered information about gastroscopy in Austria. This inquiry has enabled us to compare the techniques used and the results obtained in the diagnosis of gastric cancer. The final aim of the investigation was to obtain guidelines for the wider application of gastroscopy for the early diagnosis of gastric cancer. The level of response by Austrian endoscopists to the inquiry was high at 72.7%. The results demonstrate a considerable increase in the use of gastroscopy in Austria over the past few years. However, some of the provinces hate fallen behind others. The available equipment is not fully used and reasons for this are discussed. A close correlation is shown to exist between the number of gastric biopsies carried out and the incidence of early gastric cancer. It is further shown that the use of cytological brushing improves the results. Only one third of endoscopists, however, use this method.

Austria

[Organochlorine pesticide (DDT etc.) and polychlorinated biphenyl (PCB) compound residues in human milk (from the area of Vienna and lower Austria) (author's transl].

31 samples of human milk (Vienna and Lower Austria) were examined for the presence of organochlorine pesticide and polychlorinated biphenyl (PCB) compound residues using standard methods. In Viennese samples, mean concentrations of these residues in the milk fat were as follows: HCB 1.24 ppm, gamma-HCH 0.048 ppm, beta-HCH 0.20 ppm, DDE 3.38 ppm, DDT 1.06 ppm and PCB compounds 1.54 ppm. The mean levels of these substances in the milk fat samples from women living in the area of Mistelbach, Lower Austria, were: HCB 3.67 ppm, gamma-HCH 0.063 ppm, beta-HCH 0.28 ppm, DDE 3.92 ppm, DDT 1.76 ppm and PCB compounds 1.29 ppm. The difference between the content of HBC residues in milk samples from the city and from an intensively agricultural area is significant. The results are compared with figures from other countries. With the mother's milk the baby consumes a quantity of pesticides which is very often larger than the acceptable daily intake.

Chromatography, Gas

[Current surgical management of mammary carcinoma in Austria (author's transl)].

The incidence of mammary carcinoma in Austria remains constant. Follow-up examinations of 6000 cancer patients, representing approximately one-third of all patients operated on during the period 1960 to 1974, show that the proportion of early stages is relatively low. This is evidenced by a five-year survival rate above and a ten-year survival rate below average. The operative procedure was almost exclusively the Rotter-Halsted operation; during the last few years, the modified radical mastectomy was preferred. Results of partial resections, performed in once center only, were unsatisfactory.

Austria

Primary hyperparathyroidism in Austria: results of an 8-year prospective study.

Serum calcium determinations in 45,217 hospitalized patients during an 8 year period revealed sustained hypercalcemia in 124 (0.3%) patients. Further clinical and biochemical investigations established primary hyperparathyroidism (PHP) in at least 40 (32%) patients, an incidence of PHP of 89.6 +/- 41.5 per 100,000 patients per year. The incidence of PHP in males and females was 31.5 and 124.2 per 100,000, respectively. The highest incidence was found in females greater than 66 years of age (268.8 per 100,000). Nineteen (48%) patients showed classical symptoms of PHP, 14 (35%) patients were minimally symptomatic, and 7 (17%) patients were asymptomatic. The incidence and symptomatology of PHP in Austria is nearly the same as in other countries. Because of the multiple actions of parathyroid hormone in the body, PHP can cause debilitating symptoms but too often it remains undiagnosed clinically. Routine calcium determinations are very important and PHP must always be considered in the differential diagnosis, especially in minimally symptomatic patients.

Adult