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At least 19 recordsLinked to original sources

Changes in brain weights during the span of human life: relation of brain weights to body heights and body weights.

More than 20,000 autopsy reports from several general hospitals were surveyed for the purpose of selecting brains without a pathological lesion that had been weighed in the fresh condition. From this number, 2,773 males and 1,963 females were chosen for whom body weight, body height, and cause of death had been recorded. The data were segregated into 23 age groups ranging from birth to 86+ years and subjected to statistical evaluation. Overall, the brain weights in males were greater than in females by 9.8%. The largest increases in brain weights in both sexes occurred during the first 3 years of life, when the value quadruples over that at birth, while during the subsequent 15 years the brain weight barely quintuples over that at birth. Progressive decline in brain weight begins at about 45 to 50 years of age and reaches its lowest values after age 86 years, by which time the mean brain weight has decreased by about 11% relative to the maximum brain weight attained in young adults (about 19 years of age). Computed regression lines for brain weights versus body heights and body weights and for ratios for brain weights to body heights and weights versus age groups show clearly differential rates of change in brain weights which are less affected by sex.

Adolescent

Body height and body mass as determinants of basal blood pressure in children--The Bogalusa Heart Study.

Body height and body mass as determinants of basal blood pressure in children--The Bogalusa Heart Study. Am J Epidemiol 106:101-108, 1977. Risk factor variables for coronary artery disease were measured in a total biracial community study of 3524 children, ages 5-14 years. Anthropometric variables, serum lipids, and blood pressure (BP) were measured in a rigid randomized design. Blood pressure data were obtained with an automatic recording instrument that avoids excessive pressure readings in obese children by the use of an over-sized arm cuff bladder with a built-in infrasonic transducer. By reducing the anxiety of the child and by taking multiple readings, pressures were obtained that approached published basal levels. A multiple regression analysis showed that all measured variables could account for 39% of the systolic BP variation. Major determinants were based on weight (W) and height (H). The BP levels, when related to H and to a weight-height index (W/H3), suggest a strong influence of H and an additional influence of W/H3 on BP, both consistent and proportionate over the entire ranges of H and W/H3. The total spectrum of observed correlates of BP, resulting from the multiple regression analysis, suggests that the BP measured under basallike conditions increases as the child grows and is proportional to lean body mass and total body mass. Practical criteria for evaluating abnormal blood pressure levels in children should be based on normative values derived from body weight and body height rather than from age.

Adolescent

Analysis of body height in 829 patients with different forms of testicular pathology.

Analysis of body height was performed in the control group of 500 well-fertile men and in 829 patients with various forms of testicular pathology such as hypoplasia of testicles, unilateral and bilateral cryptorchism, hypogonadotrophic eunuchodism, and Klinefelter's syndrome. A statistically greater average height was found in bilateral cryptorchids, unilateral cryptorchids with an adequate spermiogenesis, hypogonadotrophic eunuchoids and chromatin-positive men. The greatest difference, when compared with the control group, was found in patients with a Klinefelter's syndrome. The authors hold the view that the plasmatic testosterone values are not the only factor conditioning the termination of the process of growth into height in males. Importance must also be given to the lowered sensibility of epiphysial growth zones to male sex hormone; this reduced sensibility is especially to be seen in chromatin-positive men.

Adult

Congenital malformation of the feet with low body height. A new syndrome, caused by an autosomal dominant gene.

Among 75 members of a Danish family, 12 were found with a syndrome not previously described. Clinically, the syndrome consists of low body height and rigid flat feet, with weight-bearing pain in the feet. Radiologically, the deformation of the feet is a medial synostosis between the talus and the calcaneus combined with ankle joint dysplasia. The cause of the syndrome is most probably an autosomal dominant gene with complete penetrance. No linkage was found of the gene to 18 marker genes.

Adult

[Influence of early postnatal nutrition on body height in adolescence].

Females who were purely bottle-fed during the first trimenon of life showed a significantly increased incidence of overweight at 15 years of age as compared to those who were purely breast-fed or breast plus bottle-fed. Similar findings were obtained in males. In purely bottle-fed females, furthermore, a significant positive correlation was found between the body weight at 3 months of age and body height at 15 years of age.

Adolescent

[Body weight, body height and menarche. Epidemiological study, in the Province of Pordenone, of the school population from 12 to 15 years old (12,000)].

The relation between body weight, height and the commencement of menstruation was studied in 5324 girls aged 12--15 yr attending secondary schools in the province of Pordenone. The mean age of menarche was 12 2/12 yr and varied little throughout the province. Weight and height appeared closely related to menarche. A threshold of 49.2 kg and 157.3 cm was noted. Attainment of these critical values was apparently the factor that influenced the age at which menstruation commenced.

Adolescent