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Results for “Bone Development”

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At least 19 recordsLinked to original sources
PubMed1992

[Effect of vitamin D over-dosage on the tooth and bone development of rabbits].

The paper investigated the changes of rabbit's tooth and jaw tissues by vitamin-D poisoning experiment. The results showed the dentin, periodontium, jaw bone and long bone of rabbit were all changed. X-ray showed subperiosteum absorbation and periosteum reaction. The mineral content of the rabbit's epiphysis and long bone diaphysis in experiment group were lower than that of control group. The histopathological findings were irregular hyperplasia of dentin, arrange disturbance of periodontal fibers, absorbation of the alveolar bone and mal-ossification of long bones. The above changes were more significant during 30-45 days of rabbit poisoning, after 60 days of poisoning the above signs were gradually released.

Animals↗
PubMed1975

Abnormal bone development and lameness associated with secondary copper deficiency in young cattle.

Lameness in a group of 5- to 12-month-old calves was found to be clinically, radiographically, and pathologically associated with abnormal bone development of the distal growth plates of the metacarpus and metatarsus. Copper concentrations in serum and liver were low. Serum calcium, phosphorus, and alkaline phosphatase values were normal. In pasture forage samples, sulfate, zinc, and molybdenum concentrations were high, whereas copper, calcium, and phosphorus concentrations were normal. Red blood cell (RBC) counts and hemoglobin values were within normal limits. Radiographic findings included a widened zone of cartilage and lipping of the medial and lateral areas of the physeal plate. Histologic findings included focal widenings of the growth plate consisting of tongues of uncalcified cartilage.

Animal Feed↗
PubMed1978

Sharpey fiber bone development in surgically implanted dog mandible. A scanning electron-microscopic study.

Ticonium metal implant placed surgically in the previously edentulatized adult dog mandible induced the formation of an extensive Sharpey fiber system. Sharpey's fibers extended from the peri-implant area, deep into alveolar bone. The frequency of Sharpey's fibers and the degree of their mineralization varied from scattered location and unmineralized state to heavy clustering and full mineralization. This study suggests that the formation of Sharpey's fibers and the degree of their mineralization are determined by biophysical forces of pressure received at a given site.

Alveolar Process↗
PubMed1979

Abnormal canine bone development associated with hypergravity exposure.

Chronic centrifugation of 85- to 92-day-old Beagles at 2.0 X g and 2.6 X g for 26 weeks during the time of active skeletal growth caused skeletal abnormalities in the radius and the ulna of ten of 11 dogs. The pattern of change mimicked that found in naturally occurring and experimentally induced premature distal ulnar physeal closure or delayed growth at this physis. Minimal changes in bone density were detected by sensitive photon absorptiometric techniques. Skeletal abnormalities also were found in five of the six cage-control dogs, although the run-control dogs were radiographically normal.

Animals↗
PubMed1979

The effect of protein-energy malnutrition on the development of bones in newborn rats.

Collagen synthesis, 45Ca uptake, and the half-life of 45Ca in mandibles and long bones of rat pups suckled on dams fed 25 or 6% protein diets were determined. Collagen synthesis in both mandibles and long bones was impaired in the malnourished group at an early age. Protein-energy malnutrition appears to affect different developmental processes in these two bones. The principal interference with collagen synthesis in the mandible occurs when bone proline is converted into hydroxyproline. In contrast, proline uptake from the blood for deposit in bone matrix is the step of collagen synthesis mainly affected in long bone. In addition, the critical growth period of mandible was different from that of long bone. The calcium complex fraction (calcium bound to protein plus that in inorganic salts) was the main compartment affected in the malnourished group. However, the efficiency of calcification per milligram of matrix in the calcium complex fraction of the mandible and long bone was approximately the same in the control and malnourished groups, thus suggesting that accumulation of calcium occurs in parallel with the formation of bone matrix regardless of the nutritional conditions. The half-life of 45Ca in the various calcium fractions of both types of bone was 72 hours in both the control and malnourished groups except the calcium complex portion of the long bone of the control group, which was about 100 hours.

Aging↗
PubMed1976

Ultrastructural development of bone marrow adipose cell.

The postnatal development of bone marrow adipose cells was studied by sequential examination of marrow tissue obtained from the tibia and femur of 1- to 8-week-old rabbits. The bone marrow adipocyte begins to develop 2 weeks after birth. Its cellular origin differs from the "fibroblast-like" cell that is the progenitor of the extramedullary adipocyte. The marrow pre-adipocyte is associated with the sinus endothelium and adventitial cells, but is not associated with collagen and does not contain abundant organized rough endoplasmic reticulum. Unlike the extramedullary adipocyte, the course of differentiation of the medullary adipocyte is not characterized by the appearance of glycogen; furthermore, during the coalescence of lipid droplets to form larger fat globules, cytoplasmic organelles, such as mitochondria and ribosomes, are trapped within the lipid substance to form intralipid vacuoles containing degraded cytoplasmic organelles. The possible significance of these morphologic differences between the developing bone marrow adipocyte and that of its extramedullary counterpart is discussed.

Adipose Tissue↗