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Cutaneous molt induced by calciphylaxis in the rat.

A molt, conducive to the loss and subsequent replacement of all cutaneous layers, can be induced by topical "calciphylaxis" in the rat. This is accomplished by sensitization with dihydrotachysterol followed by challenge with egg white or ferric dextran.

Animals↗

Mineralization of bacteria.

A variety of viable and non-viable bacteria became mineralized with hydroxyapatite when implanted in dialysis bags in the peritoneal cavities of rats. The microscopic pattern of mineral deposition appeared analogous to that in the formation of oral calculus. Since nonviable organisms were mineralized at an accelerated rate, bacterial metabolic processes may not be essential for mineralization.

Animals↗