PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “CHRONIC DISEASE”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 19 recordsLinked to original sources
PubMed2000

Carotenoids and chronic diseases.

Chronic diseases such as cancer and cardiovascular diseases are the major causes of deaths in North America. Dietary intake of fruits and vegetables has been suggested to have protective effects against such chronic diseases. Carotenoids are important plant pigments which are thought to contribute towards the beneficial effects of fruit and vegetable consumption. This review focuses on the role of carotenoids and particularly lycopene in chronic diseases.

Animals↗
PubMed2001

A model of self-regulation for control of chronic disease.

Chronic disease poses increasing threat to individual and community health. The day-to-day manager of disease is the patient who undertakes actions with the guidance of a clinician. The ability of the patient to control the illness through an effective therapeutic plan is significantly influenced by social and behavioral factors. This article presents a model of patient management of chronic disease that accounts for intrapersonal and extemal influences on management and emphasizes the central role of self-regulatory processes in disease control. Asthma serves as a case for exploration of the model. Findings from a 5-year study of 637 children with asthma and their care-taking parents supported that the self-regulation elements of the model were reasonably stable over time and baseline values were predictive of important disease management outcomes.

Asthma↗
PubMed1999

Clinical research databases and clinical decision making in chronic diseases.

Chronic diseases are the major source of morbidity, mortality, and resource utilization. Large-scale longitudinal databases are rapidly proliferating in both single- and multi-institutional settings, providing clinical data on a broad range of patients who receive 'real world' management. Although bias and changing medical management may limit the types of questions that can be addressed using the data contained in longitudinal clinical databases, many initial hypotheses can be generated from the data. Because chronic diseases persist over long periods of time, understanding the impact of temporal relationships, and of concurrent clinical events and contexts is critical to meaningful interpretation of clinical data. Adapting techniques initially developed for the physical sciences and for statistical process control can produce visual displays of clinical data that capture complex temporal and contextual information. With these tools, investigators can quickly explore vast quantities of clinical data, and discover new temporal relationships and emerging trends.

Case-Control Studies↗
PubMed1992

[Chronic disease, the chronic patient and his family. Psychosocial impact of diabetes mellitus].

Concerning a revision about the mutual influence between the diabetes, the diabetic and his family, the author reviews the literature about the psychosocial area of the Family Physician content's work. It is also confirmed the high prevalency of the chronic disease and the importance of the family ecosystem, not only as support but also as problem to the bearing person of such type of disease. Studies of chronic disease indicate that family dysfunction is associated with poor health outcomes. The areas which more and better have been studied in this scope are reviewed. Thus, having as backdrop the diabetes management, the family's diabetic influence in general is reviewed, as well as the parental attitudes, the family organization and the family life events. Finally, the health care team role is reviewed and particulary the role of the family physician in the management of this type of patients. It is pointed out, as example of the Family Medicine specific contribution, the improving cooperation with medical treatment from the diabetic.

Adaptation, Psychological↗
PubMed1995

Lupus erythematosus-like oral mucosal and skin lesions in a carrier of chronic granulomatous disease. Chronic granulomatous disease carrier genodermatosis.

We present a case of a young female patient who for 8 years was believed to have discoid lupus erythematosus of the skin and oral mucosae. Only after her infant son had a near-fatal pulmonary infection was the diagnosis of chronic granulomatous disease made and her lupus erythematosus-like mucocutaneous lesions recognized as manifestations of her carrier status for chronic granulomatous disease. The purpose of this report is to raise awareness of and better characterize the mucocutaneous manifestations of carriers of chronic granulomatous disease. Early identification of carriers permits genetic counseling and prenatal diagnosis and forewarns pediatricians so that they can provide better care for affected infants.

Adult↗
PubMed1978

Acid hydrolases in monocytes from patients with inflammatory bowel disease, chronic liver disease, and rheumatoid arthritis.

A sensitive technique was used to estimate two acid hydrolases--N-acetyl-beta-glucosaminidase (N.A.G.) and beta-glucuronidase (B.G.)--produced by peripheral-blood monocytes. Enzyme levels were measured after in-vitro incubation of monocytes with or without stimulation by zymosan and endotoxin. Compared with controls, enzyme production and release in inflammatory bowel disease, chronic liver disease, and rheumatoid arthritis were markedly raised. It is suggested that various stimuli, including immunological ones, may be responsible for the release of such enzymes from monocytes and that such release may be a factor in the production of the chronic inflammation seen in these disorders.

Acetylglucosaminidase↗
PubMed2000

[Psychosomatic principles and therapy of chronic diseases].

Chronic illness is the main problem in modern medicine. The manner in which a person psychologically faces his chronic illnesses and attempts to deal with them represents his individual coping process. Psychosocial disturbances are more frequently present in the chronically ill than in the physically healthy and require application of step-wise psychotherapeutic treatment measures. Different problems and disturbances demand distinct therapeutic approaches. The therapeutic measures range from a comprehensive psychosomatic extensive treatment by a physician to professional psychotherapy.

Chronic Disease↗