The susceptibility to praziquantel of Schistosoma haematobium in the baboon (Papio anubis) and of S. japonicum in the vervet monkey (Cercopithecus aethiops).
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Animals↗
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Results for “Chlorocebus aethiops”
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Representation of fovea in the striate cortex of vervet monkey, Cercopithecus aethiops pygerythrus.
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Animals↗
Bacterial myocarditis in African green monkeys (Cercopithecus aethiops).
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Animals↗
The effects of orbitofrontal lesions on the aggressive behavior of vervet monkeys (Cercopithecus aethiops sabaeus).
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Aggression↗
Formazan cells in protein and protein-calorie malnutrition.
Formazan cells were less numerous in the peripheral blood of vervet monkeys (Cercopithecus aethiops) receiving a "O" protein-low calorie diet than in animals fed a full or a protein but not calorie deficient diet.
Animals↗
Short-term effects of aflatoxin B1 on serum lipids in subhuman primates.
Aflatoxin B1 significantly depressed serum lipid levels in specimens of Cercopithecus aethiops, Cercopithecus mona, Erythrocebus patas and Papio anubis. Serum cholesterol, total phospholipids and total lipids were not affected to the same extent.
Aflatoxins↗
Reinfection of vervet monkeys (Cercopithecus aethiops) with Borrelia hermsii.
Two of 4 untreated vervet monkeys infected with Borrelia hermsii survived and were resistant to reinfection for at least 1 year. Seven of 9 vervets receiving tetracycline could be reinfected after 12 to 36 weeks. Immobilizine could be demonstrated for a shorter time in treated than in untreated vervets.
Animals↗
Human-type A-B-O blood group antigens of Ethiopian vervet monkeys (Cercopithecus aethiops) in the wild.
Human type A-B-O blood group antigens were tested in a local population of Ethiopian vervet monkeys (Cercopithecus aethiops). One animal was of group AB, the others were A. This represents a lower rate of polymorphism at this locus than has been observed among South African populations of the same species.
ABO Blood-Group System↗
Plasma amine oxidase activity in 136 normal rhesus monkeys: relationships between enzyme activity and age, sex and genetic factors.
Normative data on plasma amine oxidase activity were obtained for four primate species, M. mulatta, M. arctoides, C. aethiops and H. sapiens. Significant between-species differences in activity were observed. In a large sample of M. mulatta, no significant relationship between age and plasma amine oxidase activity was observed, but adult males had significantly higher enzyme activities than adult females.
Age Factors↗
Polymorphonuclear neutrophilic leukocytes in protein deficiency.
The number of white blood cells and of polymorphonuclear leukocytes remained unchanged in vervet monkeys (Cercopithecus aethiops) receiving a "O" protein diet. The motility of the polymorphonuclear leukocytes and their phagocytic and killing indices with and without leukokinin stimulation decreased in protein-depleted animals. Acid cathepsin decreased, DNA relatively increased, and peroxidase, alkaline phosphatase, acid phenylphosphatase, and lysozyme reached higher levels in the polymorphonuclear leukocytes of animals on a "O" protein diet.
Animals↗
Behavioral effects of thymoleptics in vervet monkeys (Cercopithecus aethiops).
Desmethylimipramine (DMI) exerts diverse quantitative effects on the gross behaviour of monkeys. Excitatory as well as sedative effects were observed, which varied according to the general animal temperament. Results resembling those obtained with DMI were observed using chlorimipramine and iprindole, although the effects of iprindole were less marked. Chlorimipramine also produced immobilization and postural change. The results are discussed in relation to behavioral effects of thymoleptics in humans, and the use of monkeys in preclinical testing of thymoleptic drugs is suggested.
Animals↗
Malnutrition and susceptibility to infection with Vibrio cholerae in vervet monkeys (Cercopithecus aethiops). 2. Response of vervet monkeys on protein, B-vitamin complex and calorie-deficient diets to infection.
Five groups of vervet monkeys (Cercopithecus aethiops) were fed regular monkey chow, low protein (LP), low B-vitamin complex (LBV), LP-LBV, or low protein- low calorie (LP-LC) diets, respectively. After eight weeks the animals were infected with cholera vibrios. IgG, IgA and IgM increased in the sera of all animals after the challenge but the avidity of the immunoglobulins was lower in vervets on LP diets. Diarrhea and excretion of vibrios lasted longer in animals consuming less protein.
Animals↗
Social isolation and other behavioral changes in groups of adult vervet monkeys (Cercopithecus aethiops) produced by low, nonchronic doses of d-amphetamine.
Doses (0.1--0.7 mg/kg body weight) d-amphetamine were administered to three independent groups of green vervet monkeys (Cerecopithecus aethiops). Each group formed a triad with one male and two females. Amphetamine changed both the individual and the social behavior patterns significantly. Stereotypy and social isolation (withdrawal) were characteristic features of the amphetaminized animals. Also stereotyped social grooming was observed. The results are discussed in relation to behavior changes seen in amphetamine psychoses and in naturally occurring endogenous psychoses. It is emphasized that the study of patterns of behavior is an important object of research and relevant line in future investigations on psychopathology.
Animals↗
Actin filaments in trabecular endothelial cells in eyes of the vervet monkey. (Cercopithecus aethiops).
An electron microscopic study was performed on the trabecular meshwork of two monkeys (cercopithecus aethiops). Specimens from one animal revealed numerous cytoplasmic filaments of 45-65 A thickness in endothelial cells both on the trabeculae in the wall of Schlemm's canal after conventional glutaraldehyde and osmium fixation. Using a histochemical technique it was shown in specimens from the other animal that these filaments consist of actin material. This evidence of intracellular actin filaments in the trabecular endothelium indicates that these cells have contractile properties, and the possible significance of this finding for the regulation of outflow facility of aqueous humour is suggested.
Actins↗
Malnutrition and susceptibility to infection with Vibrio cholerae in vervet monkeys (Cercopithecus aethiops). 1. Induction of protein, B-vitamin complex and calorie malnutrition.
Five groups of eight vervet monkeys (Cercopithecus aethiops) were fed regular monkey chow, low protein (LP), low B-vitamin complex (LBV), low protein - low B-vitamin complex (LB-LBV), or protein - low calorie (LP-LC) diet, respectively, for eight weeks. Hematocrit values, hemoglobin, BUN, total protein, albumin, riboflavin and body weight decreased, the ratio of dispensable/indispensable amino acids increased in all animals receiving a deficient diet. Total globulin, IgG and IgM remained unchanged in vervets on LBV diet; panthotenic acid and cyanocobalamin in animals receiving LBV, LP or LP-LC chow; and pyridoxal on the LP or LP-LC diet.
Animals↗
Effect of oral estramustine phosphate on pituitary, gonadal, and adrenal function in the green monkey (Cercopithecus aethiops sabaeus).
We studied the effects of estramustine phosphate on pituitary, gonadal, and adrenal function in the green monkey. A 2-week course of estramustine phosphate (75 mg per day) reversibly suppressed the luteinizing hormone and testosterone response to luteinizing hormone-releasing hormone but did not affect pituitary-adrenal function assessed by the 11-deoxycorticosterone response to metyrapone. Treatment with oral estramustine phosphate also resulted in a significant increase in corticosteroid-binding globulin but did not affect a series of liver enzymes nor hematology. The results are consistent with a pure estrogen effect produced by hydrolysis of the carbamate-ester bona at a site distant from estrogen target tissues and could explain most of the reported in vivo effects of this compound.
Administration, Oral↗
[Analysis of the biological effect of city smog extract. V. Comparative investigations on the effect of city smog extracts on DNA synthesis of Syrian hamster kidney and embryonic cells and of African green monkey kidney cells in vitro (author's transl)].
We analysed the effect of two samples of city smog extract from Bochum and Duisburg on DNA synthesis of mammalian cells in vitro. As a test system we used tissue cultures of kidney and embryonic cells from the Syrian golden hamster and monkey kidney cells from Cercopithecus aethiops. DNA synthesis of cells was measured by autoradiography using 3H-Thymidine. Both samples of city smog extract exerted a dose-dependent decrease of the rate of DNA synthesis in tissue culture cells. These alterations of nucleic acid metabolism were expressed by a reduction of DNA-synthesizing cells and by a delay of entrance of cells in DNA synthesis. High concentrations of city smog extracts induced a large number of cell necroses. Monkey kidney cells were more sensitive to the toxic action than hamster cells. Furthermore the city smog extract from Duisburg showed a stronger toxic effect than the extract from Bochum.
Air Pollutants↗
Nonhuman primates: laboratory animals of choice for neurophysiologic studies of sleep.
A systematic study was made of several nonhuman primates to learn more about their relative usefulness for studies of sleep. Species studied included the Guinea baboon (Papio papio), Kenya or yellow baboon (P cynocephalus), olive baboon (P anubis), sacred baboon (P hamadryas), vervet monkey (Cercopithecus aethiops), rhesus monkey (Macaca mulatta), bonnet monkey (M radiata), crab-eating monkey (M fascicularis), patas monkey (Erythrocebus patas), chimpanzee (Pan troglodytes), mongoose lemur (Lemur mongoz), black lemur (Lemur macaco fulvus), and bushbaby (Galago senegalensis). Comparisons were made of electroencephalographic activity, states of vigilance, and responses to sleep-waking drugs. The results showed that there were major similarities among the genera studied as well as individual intrageneric and intraspecies differences. It was concluded that the chimpanzee, olive baboon, and rhesus monkey were the best species for comparative studies, and that the rhesus monkey was the best single model because of its well defined sleep organization and ease of handling and housing.
5-Hydroxytryptophan↗