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At least 19 recordsLinked to original sources
PubMed1977

Management of persistent filtering cicatrix following cataract extraction.

We used a safe and simple surgical technique in the management of persistent filtering cicatrices after cataract extraction. The edematous, friable filtering cicatrix was excised entirely and a healthy fornix-based conjunctival flap was sutured over the fistula. Invariably, the fistula was very small, usually only large enough to admit a 27-gauge needle. Of the 27 eyes treated with this technique, there were two failures, but no other complications.

Aged↗
PubMed1978

Effect of puromycin treatment on the regeneration of hemisected and transected rat spinal cord.

The effect of puromycin on spinal cord regeneration was studied following implantation into the site of spinal cord hemi- or transection of Gel-foam saturated with puromycin (1 mM) in a saline carrier, implantation of Gel-foam sponge saturated with saline (carrier control), or lesion alone (lesion control). The spinal cords of 107 rats were studied with light and electron microscopy 7, 14, 30, 60 and 90 days postoperative (DPO). Spinal cord hemisected animals developed a dense cicatrix at the site of lesion replete with connective tissue, blood vessles, and myelinated and unmyelinated nerve fibres which could be traced to peripheral sources. Rostrally at the C.N.S.--cicatrix interface, there were reactive neuroglial cells, occasional nerve fibres and finger-like projections of spinal cord (due to cavitation lesions) which contained neuroglia, axons and dendrites. Implantation of saline in Gel-foam resulted in the same morphology as in hemisected animals except for increased lesion size due to mechanical factors and decreased cicatrix density during the first 30 DPO. Puromycin treatment resulted in a cicatrix with initial decreased cell density but which contained a new class of nerve fibres at 30 DPO. These nerve fibres were oriented in a rostro-caudal direction, were unmyelinated, 0.1-0.2 micron in diameter and had expanded smooth endoplasmic reticulum. Some of these nerve fibres were degenerating at 30 DPO and all were absent by 60 DPO. The puromycin-treated spinal cord within 200 micron rostral to the basal lamina contained nerve terminal conglomerates, which resembled boutons, in fascicles from 30-90 DPO (duration of experiment). Hemisection of the spinal cord by crushing 1-1 1/2 segments rostral to the site of puromycin implantation at 30 DPO resulted in degeneration of these nerve fibres in the cicatrix as well as the degeneration of nerve terminal conglomerates just rostral to the basal lamina. The regenerative capacity of the spinal cord is discussed in relationship to these findings.

Animals↗
PubMed1976

[Combined treatment of a cicatrised post-intubation complication with surgery and medication summary (author's transl)].

A case of postintubation laryngotracheal injury is described. The paramedian position of the vocal cords was found to be a consequence of cicatrix in the area of the posterior commissure, and by a luxation with ankylosis of the right cricoarytenoid joint. Paresis of the recurrent laryngeal nerve was excluded by electromyography. Multiple incisions of the cicatrix failed to correct the problem, whereas subsequent incision followed by intensive therapy with fludrocortisone and hyaluronidase was successful in management. In administering the medication, a new simplifed method for translaryngeal injection is described.

Adult↗
PubMed1977

The abductor digiti minimi muscle flap.

The problems of extensive scarring involving the median and ulnar nerves at the wrist are discussed. Possible methods of separating the dermal cicatrix from the nerves are skin flaps or muscle flaps. A case is presented in which an abductor digiti minimi muscle flap was used. The reasons for this choice are discussed and the technique described.

Aged↗
PubMed1979

Pseudoneurilemoma of the spinal canal.

Two cases are presented with the myelographic appearance of an intradural tumor believed to be neurilemoma. In one instance the defect was undoubtedly caused by a cicatrix which developed over a period of years, consequent to postoperative spinal fluid fistula. In the second case a herniated disk at the L2-3 level was mistaken as artifact and its true nature was revealed only at operation seven years later. It was suspected to be neurilemoma because of the myelographic appearance and persistence of the lesion.

Cicatrix↗
PubMedDate not supplied

Zigzag incisions for improved exposure and scarring.

Incisions for elective orthopedic procedures frequently result in scars that are unesthetic (wide and hypertrophied) and impeded function (are inelastic). The best cicatrix is obtained when the operation can be performed through an incision that follows the lines of skin tension (transverse exposure). If longitudinal exposure is required to gain access to the deeper structures, the best esthetic and functional result is obtained by the zigzag incision. Moreover, the zigzag incision affords a wider exposure than a long straight incision, thus greatly facilitating the operative procedure.

Cicatrix↗
PubMed1978

Radial neuronal assemblies, ectopia and necrosis of developing cortex: a case analysis.

Reduced size of convolutions and midcortical laminar necrosis are approximately co-extensive in the cerebral hemispheres of a child, one of twins, dying at 18 months. Because the underlying laminar arrangement of neurons and the basic gyral pattern are normal, the cortical damage probably occurred not earlier than the third trimester of gestation. Neurons surviving above and below the zone of tissue necrosis, like their homologs in normal cortex, are entrained in multineuronal radial assemblies. Below the zone of necrosis the relative positions of radially adjacent neurons are unaltered. Above, however, in places where the molecular layer is reduced in width, neurons are displaced radially outward toward the pial surface. In places the pia is breached and bridged by a mesenchymal-glial cicatrix. Where this has happened neurons have migrated beyond the cerebral boundary and have established an ectopia in the subarachnoid compartment. These observations suggest that relatively undifferentiated intracortical neurons are held in radial assemblies by bonds which prevent their tangential displacment. The molecular layer appears to serve as a barrier to their radial displacement.

Cerebral Cortex↗
PubMed1978

Spontaneous resolution of colonic strictures caused by necrotizing enterocolitis: therapeutic implications.

Colonic strictures are now a well recognized complication in infants surviving necrotizing enterocolitis. We describe the clinical course of seven infants with colonic strictures after necrotizing enterocolitis. Only two demonstrated the finding of fixed fibrotic stricture described in the literature, while the remaining five showed atypical radiographic and pathologic features. Two of the five showed partial or spontaneous resolution of post-necrotizing enterocolitis colonic stenoses on follow-up barium enema studies. In three of four patients with colonic resections, the histopathologic examination revealed a surprising absence of irreversible fibrosis or cicatrix formation. Current surgical practice dictates elective resection of these narrowed colonic segments. The radiologic and pathologic findings in our series of patients suggest surgical resection may be unnecessary in selected cases.

Colon↗