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At least 19 recordsLinked to original sources
PubMed1992

[The magnetic resonance of small hepatocarcinoma. A comparison with echography, computed tomography, digital angiography and computed tomography with lipiodol].

Diagnostic techniques as a whole and periodic ultrasonography (US) in particular frequently allows tumors < 3 cm (small hepatocellular carcinomas) to be detected in patients suffering from liver cirrhosis. Multifocal diseases are a major limitation to surgery. Recently, MR imaging has shown its capabilities in the diagnosis of small hepatocellular carcinomas. In our study the diagnostic value of MR imaging was compared with that of US, of pre- and post-contrast CT, of digital angiography and of CT after lipiodol injection (Lipiodol CT). The morphologic and signal intensity MR features of small hepatocellular carcinomas were investigated. Fifteen cirrhotic patients with 31 nodules of hepatocellular carcinoma < 3 cm were examined. All patients were studied with US, MR imaging, angiography and Lipiodol CT; 12/15 patients underwent CT. Histologic confirmation was obtained in 12 nodules (2 at surgery and 10 by means of percutaneous biopsy); in the extant 19 cases the diagnosis was made by combining US, CT, MR, angiographic and lipiodol-CT findings; in 9 tumors < 1 cm Lipiodol retention one month after angiography was considered as diagnostic. MR imaging detected 21/31 nodules (63%), US 22/31 (66.6%), CT 12/24 (50%), angiography 24/31 (74%), lipiodol CT 29/31 (92.5%). Mc Nemar test showed no difference in sensitivity between MR imaging and CT, MR and angiography, MR and US, lipiodol CT and angiography; however, the differences between the detection rates of MR imaging and Lipiodol CT and CT and lipiodol CT and US were statistically significant (p < 0.05). The difference in sensitivity between the detection rates of lipiodol CT and US was just above the threshold value which is usually considered significant (p = 0.065). One false positive was observed on US and none with MR, CT, angiography and lipiodol CT. On Se T1-weighted images 18 nodules were hyperintense, 2 isointense and 2 hypointense; on proton-density images 14 nodules were hyperintense, 7 isointense and none hypointense. On SE T2-weighted images 18 nodules were hyperintense, 3 isointense and none hypointense. A pseudocapsule was seen in 10/17 nodules (58%), especially on T1-weighted images. Accuracy and limitations of each technique and morphologic and signal intensity MR findings of small hepatocellular carcinoma are discussed. We believe that US is still the best diagnostic technique for the screening of hepatocellular carcinomas in cirrhotic livers.(ABSTRACT TRUNCATED AT 400 WORDS)

Aged↗
PubMed1978

Intracranial pearly tumors: the roles of computed tomography, angiography, and pneumoencephalography.

The findings is computed tomography (CT) and other radiological examinations in nine histologically proven cases of intracranial pearly tumors are presented. The CT findings include a low density lesion with no enhancement after contrast medium injection and in some cases a lesser degree of mass effect than would be expected from the size and site of such lesions. Pneumoencephalography is superior to CT in detecting suprasellar pearly tumors when they are isodense with the cerebrospinal fluid.

Adult↗
PubMed2026

Comprehensive assessment of vasospastic angina using coronary computed tomography angiography: synergistic value of the presence of myocardial bridge, perivascular inflammation, and myocardial extracellular volume fraction.

AIMS: Coronary computed tomography angiography (CCTA) has evolved beyond anatomical assessment to include sophisticated tissue characterization. While an elevated perivascular fat attenuation index around the right coronary artery (FAI-RCA) is known to reflect coronary inflammation in vasospastic angina (VSA), recurrent vasospasms may also induce chronic subclinical myocardial injury and subsequent remodelling, potentially associated with an increased myocardial extracellular volume fraction (ECV). However, the diagnostic integration of ECV and FAI-RCA for identifying VSA in patients with angina with non-obstructive coronary arteries (ANOCA) remains to be elucidated. METHODS AND RESULTS: This study included consecutive ANOCA patients who underwent CCTA with a dedicated ECV protocol, followed by an invasive spasm provocation test. Comprehensive CCTA analysis quantified both FAI-RCA and the transmural ECV gradient (the difference between endocardial and epicardial ECV: ECVEndo - ECVEpi). Of the 100 patients analysed (mean age: 65.3 &#xb1; 11.8 years; 55% male), 27 were diagnosed with VSA. Multivariable logistic regression analysis identified transmural ECV gradient [odds ratio (OR): 1.12, 95% confidence interval (CI): 1.01-1.25], presence of myocardial bridging (MB) (OR: 3.49, 95% CI: 1.25-9.74), and high FAI-RCA (> -70.95 Hounsfield units [HU]) (OR: 5.79, 95% CI: 2.06-16.30) as significant independent predictors of VSA (all P < 0.05). Notably, the integration of transmural ECV gradient provided incremental diagnostic value beyond FAI-RCA and MB, as assessed by the Net Reclassification Improvement and Integrated Discrimination Improvement. CONCLUSION: A multi-parametric CCTA approach potentially identifies patients at high risk for VSA. The significant association of the transmural ECV gradient with VSA suggests that myocardial remodelling imaging provides a novel diagnostic window into the cumulative myocardial impact of vasospasm, independent of active adipose tissue inflammation and the presence of MB.

Humans↗
PubMed1979

Angiography and computed tomography in the evaluation of cerebral venous malformations.

The information obtained by computed tomography (CT) and cerebral angiography is compared in eight cases of cerebral venous malformation. Angiography was found to be more reliable for detecting the presence and specific nature of these malformations. Pathological and radiographic differential features between the various forms of cerebral vascular malformations are discussed.

Adult↗
PubMed1979

Cerebral venous angioma: correlation of radionuclide brain scan, transmission computed tomography, and angiography.

Three cases of intracerebral venous angioma, a rare vascular malformation, were studied by radionuclide brain scan, transmission computed tomography (TCT) and angiography. In each case, the radionuclide flow study demonstrated a typical area of abnormal increase in activity during the venous phase; in two of the cases the arterial phase was also abnormal. Each contrast angiogram demonstrated a normal arterial distribution and a characteristic network of abnormal veins that converged to a large transcerebral draining vein. The TCT scans showed enhancing, curvilinear densities; while not specific, this finding should suggest the possibility of venous angioma in the brain.

Adult↗
PubMed2026

Baseline Computed Tomography Coronary Angiography and Polygenic Risk Profiles in Adults With Type 2 Diabetes: A Cross-Sectional Analysis From the VOLTAIRE Study.

AIMS: To characterise baseline clinical, anatomical, and genetic cardiovascular risk profiles in participants enrolled in the VOLTAIRE (Evaluation of Polygenic Scores and CT Imaging in Risk Factor Modification in Patients with Type 2 Diabetes) study and examine concordance across these domains. METHODS: This analysis included adults with T2D who completed baseline computed tomography coronary angiography (CTCA) and polygenic risk score (PRS) assessment prior to randomisation in the VOLTAIRE study. Coronary atherosclerosis was evaluated using coronary artery calcium (CAC) score and CTCA-derived stenosis severity. Clinical risk was assessed using the New Zealand Society for the Study of Diabetes 5-year cardiovascular risk calculator. Polygenic risk for coronary artery disease was assessed using a genome-wide PRS and categorised into tertiles. RESULTS: Among 126 participants with T2D (mean age 57.5&#x2009;&#xb1;&#x2009;8.7&#x2009;years; 62.7% male), coronary atherosclerotic burden was highly heterogeneous: 34.9% had CAC&#x2009;=&#x2009;0, whereas 19.8% had CAC &#x2265;&#x2009;400. Moderate-to-severe coronary stenosis (&#x2265;&#x2009;50%) was present in 40.5% of participants overall, including 20.4% of those classified as low clinical risk. PRS distribution was variable (low 37.3%, intermediate 35.7%, high 27.0%). Overlap between anatomical, genetic, and clinical domains&#xa0;was limited, with only 8.7% of participants classified as high risk across all three. CONCLUSIONS: Substantial heterogeneity and limited overlap&#xa0;exist between anatomical, genetic, and clinical cardiovascular risk measures in T2D. These findings support a multimodal approach to risk assessment integrating imaging and genetic profiling. TRIAL REGISTRATION: https://www. CLINICALTRIALS: gov; ID: NCT07091162.

Aged↗
PubMed1979

[A comparison of cerebral angiography and computer tomography in patients with strokes (author's transl].

The computer tomographic findings in 230 patients with a clinical diagnosis of strokes or cerebral infarcts are described. In 185 of these patients cerebral angiography was performed in addition. The size and localisation of infarcts as shown on the computer tomogram were compared with the changes found in the carotid angiogram and were also related to the localisation of occlusion or stenosis of the corresponding extra- and intracranial vessels. In the presence of a normal carotid angiogram, CT may show infarcts of varying localisation and size; with stenoses or occlusion of the extracranial portion of the internal carotid artery, the infarcts tend to be smaller and that, in the presence of occulsions of the intracranial cerebral vessels, infarcts tend to be more extensive and to correspond to the territory supplied by the occluded vessels. Twenty-eight intracerebral haematomas and nine cerebral tumours were found amongst patients who presented as cerebral infarcts, with little evidence of massive cerebral bleeding; these are discussed separately.

Adolescent↗
PubMed1977

Neck and mediastinal angiography by computed tomography scan.

CT scanning of the neck and upper mediastinum is a valuable tool in the differential diagnosis of soft-tissue tumors. Visualization of the major vessels in the neck, which aids in the study, can be accomplished by a rapid intravenous drip infusion technique during the actual scanning, a new approach to contrast enhancement.

Angiography↗
PubMed1975

Computer intravenous angiography.

Computer tomography could be useful in demonstrating lesions of intracranial vascular structures. Experimental methods aimed at achieving this are presented and clinical examples using intravenous angiography are given. The factors involved by the demonstration of intracranial vessels are discussed.

Cerebral Angiography↗
PubMed1979

The complementary nature of computed tomography and angiography in the diagnosis of cerebellar hemangioblastoma.

Cerebellar hemangioblastomas were seen in seven persons, five being members of the same family. All were studied with constrast enhanced CT scans and vertebral angiograms. The CT scans were superior for demonstrating the cystic component of the tumors and associated hydrocephalus, features not usually evident on the angiograms. The angiograms were superior for revealing the vascular nature, supply and drainage of the tumors. In several patients the angiograms revealed more tumors than could be seen by CT. Both CT and angiography contribute important information in the diagnosis of these neoplasms.

Adolescent↗
PubMedDate not supplied

[Ultrasound, computer tomography and angiography in the diagnosis of dissecting aortic aneurysm].

The findings obtained by ultrasound, CT and angiographic examinations of 75 patients with dissecting aortic aneurysms operated on at the M.M.A. are analysed. The aim of each particular method was to detect the presence of dissection, the aortic entrance tear and type of dissection. These findings were compared with the operative findings. On the basis of the analysis it has been concluded that the precision of the diagnosis obtained by angiography was 93%, by CT 74% and by ultrasound 69%.

Aortic Dissection↗
PubMed1978

[Conventional contrast media examinations and computer tomography in space-occupying processes (author's transl)].

In 1977, more than 2,000 patients were examined in our department of neuroradiology by means of angiography, computed tomography, and in some cases also by pneumoencephalography. The value of the various neuroradiological examinations is discussed taking as an example two patients suffering from intracranial space-occupying processes of different etiologies. Consequently, the differential diagnostic problems occurring are discussed casuistically. It is demonstrated that correct diagnosis can often be achieved only by use of all the results of the different neuroradiological methods, together with precise knowledge of the course and the clinical symptoms.

Aged↗
PubMed1978

[Abdominal computer tomography].

In computer tomography of the abdomen the amount of diagnostic information obtained depends on the organ system examined and correlates with the topographical anatomy. The information gained by this non-invasive method results from the demonstration of contour alteration and from inherent density differences. Although at this point in time, while the process of evaluation is still in progress, it is too early to formulate definitive guidelines on the indications for computer tomography of the abdomen, we suggest, on the basis of experience hitherto, that computer tomography of the adrenals and the pancreas is better than the previously known image-producing diagnostic methods. The overall diagnostic value of computer tomography of the liver and spleen, depending on the pathology in question, is apparently at least equal to sonography, nuclear medicine and angiography. Computer tomography of the gastrointestinal tract and the kidneys, when compared to other diagnostic radiographic and sonographic investigations, at present adds little information, and for this reason has limited application in these systems. In contrast to this is the highly instructive computer tomographic examination of the extrarenal retroperitoneal space.

Abdomen↗
PubMed1979

Surgical treatment of giant pituitary adenomas.

Multidirectional extension and invasive spread are important features of giant pituitary adenomas. Operability cannot be established merely by determining the size of the most prominent part of the tumour. Detailed radiological evaluation with plain films, computed tomography, angiography, and air studies all contribute to evaluation of the precise anatomy before surgery. In the final decision risks of surgical treatment must be balanced against the patient's age and prospects of long-term useful survival. Unfavourable cases for surgical treatment in our hands were those tumours embedded in the hypothalamus with thalamic and posterior extensions. Partial removal of such cases gave poor results. Where the mass proves soft, radical excision may be possible, but not otherwise. Limited biopsy for histological study, followed by a shunt procedure and x-ray therapy seems still the only recourse.

Adenoma↗