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At least 19 recordsLinked to original sources

Computer-assisted differential diagnosis of laboratory abnormalities and follow-up testing. Evaluation of the accuracy of a computer program.

An evaluation is made of a computer program which generates a differential diagnostic list given a set of input data obtained from an admission chemistry screening profile. The program is tested by supplying input data on patients for whom diseases are known. The laboratory data from 367 patients are examined. Accurate computer diagnosis is obtained in many disease categories. The original computer program is modified to suggest the follow-up tests indicated based on the diagnoses it makes. By using this program and some additional clinical input from the physician, the clinical pathologist can select the most appropriate computer diagnosis and begin the follow-up testing. Accelerated diagnosis and patient care should result.

Aged

A computer program for the on-line computation of cardiac output from thermodilution curves.

An accurate, rapid calculation of Cardiac Output is of great importance during the treatment of critically ill patients. This paper describes a complete, self-contained mini-computer system, based on a Data General NOVA 1220 which can accurately sample data and compute the results in about 30 sec. The system uses the thermodilution method with a Swan-Ganz catheter to collect data and a weighted least-squares technique to compute the results.

Cardiac Catheterization

[Computer tomographic demonstration of lymph node metastases from malignant testicular tumours. A comparison of lymphography and computer tomography (author's transl)].

Lymphography and computer tomography was performed on 64 patients with malignant testicular tumours in order to demonstrate lymph node metastases. In 60 patients it was possible to confirm the findings by surgery. In 43 patients there was agreement between the findings of the computer tomogram and the lymphogram. In 39 of these patients lymph node metastases had been demonstrated, in three there was a false negative and in one a false positive. Amongst the patients in whom there was a descrepancy between the two types of examination, the CT findings were confirmed histologically in twelve, and the lymphographic findings in nine. In 12.5% CT added significant additional information. Accuracy of lymphography was 73% and of computer tomography 80%. Specificity for each examination was 79%.

Adult

Distributed laboratory computing. Integration of a laboratory computer into a hospital information system.

The University of Iowa Hospitals and Clinics, a large teaching hospital and tertiary care referral center, has implemented a vendor-supplied laboratory computer package operating on a dedicated minicomputer. A high-speed communications link allows the laboratory computer to share patient administrative, census, and test result data with the central hospital information system on an interactive basis. Operational characteristics of the system are discussed, and special attention is given to the critical problems and advantages of interfacing two computers.

Computers

Computational analysis and dosimetric evaluation of a commercial irregular-fields computer program.

The proper evaluation of the accuracy of a new computer program for radiation-therapy dosimetry requires consideration of both the mathematical algorithm used in the program and the performance required in clinical applications. As an example, our evaluation of the irregular-fields dosimetry program currently marketed by SHM for their Rad-8 system is described. The evaluation begins with an explanation of the mathematical computation described. The evaluation begins with an explanation of the mathematical computation method, with emphasis on the points where the calculation differs from previous methods. Next, the procedure for setting up the beam data file is discussed. Finally, a step-by-step procedure is described in which calculated doses are compared with measured doses, using a Varian Clinac-4 with lead flattening filter, and the limits within which a +/- 5% accuracy is attainable are estimated. Some sources of error and areas for possible improvements are mentioned.

Computers

[Continuous automatic ECG analysis using a computer with the cardiac signal directly led in from the patient (II). The diagnosis of heart rhythm disorders using a computer].

It is shown that appraisal and comparison of the duration of the R-R intervals in continuous surveillance of patients by means of electronic computers on the on-line regimen provides for automatic diagnosis of most types of disorders of the cardiac rhythm. The elaborated criterion of arrhythmic cardiac contraction (ACR-R), which takes into account not only the absolute value of the time between heart contractions but also the trend of the changes in the next R-R interval, provides a high percentage of revealed arrhythmic contractions. Disorders of the rate of cardiac contractions may be diagnosed by means of an electronic computer by comparison between the mean value of intervals of normal duration and the preset threshold values. Disorders of the rhythm may be diagnosed by means of an electronic computer by assessment and comparison of the arrangement of the combinations of short, normal, and long R-R intervals. The elaborated algorithms are described in detail and the block diagrams of the programs are shown.

Arrhythmia, Sinus

1978 memorial award paper: a computer-aided technique for overlaying cerebral angiograms onto computed tomograms.

We have developed a method which uses a digital computer to combine angiographic images of the cerebral vasculature with a computed tomogram of the brain. The procedure is simple and could be implemented in any radiology department equipped with both a CT scanner and a bi-plane angiography suite. We have performed the entire process in prototype on phantoms and on a patient and have produced images that appear accurate and informative.

Brain

Computer reconstructed sagittal and coronal computed tomography head scans: clinical applications.

Recent technical advances to computed tomography (CT) have enabled evaluation of the head in multiple planes. A technique that utilizes computer reconstruction of data from 3 mm contiguous transverse scans to display images in sagittal and coronal planes is described. The clinical usefulness of this technique is discussed and illustrative cases are presented. Multiple plane CT evaluation has proven a valuable adjunct to axial plane CT scanning, which can provide better definition of the extent of lesions, facilitate treatment, and improve diagnostic accuracy in many cases.

Adolescent

[Fast computer tomography for investigation of the heart--"computer cardiotomography". Methods and early results (author's transl)].

The early results in the investigation of normal and pathological hearts using fast computer tomography are presented. By means of tomographic sections of cadaver hearts, it has been shown that it is possible to distinguish the ventricular cavities and individual cardiac walls by this non-invasive method. Changes in volume of the ventricles and atria due to various forms of stress are easily distinguishable. Myocardial scars can be distinguished from other circumscribed myocardial defects. The particular advantages of this method, which is non-invasive, painless and easily repeatable, do not need to be stressed. The technique adds a significant dimension to previously available non-invasive diagnostic methods, such as ultrasound echo-cardiography.

Aortic Valve

Computed tomographic cavo-urography: lower-extremity contrast infusion simultaneous with computed tomography of the retroperitoneum.

Successful opacification and distention of the inferior vena cava was obtained simultaneously with computed tomography by contrast infusion through a lower-extremity vein. Images obtained by this method displayed retroperitoneal anatomical relationships to better advantage, permitting more accurate interpretation of the upper retroperitoneum, particularly in lymphoma.

Contrast Media

Effective atomic number and electron density as measured with a computed tomography scanner: computation and correlation with brain tumor histology.

The mathematical basis and methodology for determining the effective atomic number and electron density of a tissue are presented. Cranial computed tomography (CT) scanning is performed at two different energy levels, both with and without contrast enhancement. The histology of 15 brain tumors has been correlated with the effective atomic number and electron density of the tumor, with parameters of the linear attenuation coefficient, and with statistical values of the CT numbers. The most useful value in separating gliomas from meningiomas from metastases appears to be the percentage change of effective atomic number following contrast enhancement.

Absorptiometry, Photon