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At least 19 recordsLinked to original sources
PubMed2005

Inflammatory pseudotumor of the liver revealing gynecological Corynebacterium infection.

Inflammatory pseudotumor (IPL) of the liver is a rare benign clinicopathologic entity, which has been associated with infectious conditions, including alimentary, digestive tract and mouth infections. We report a new case, where a patient developed hepatic IPL that revealed endometritis related to Corynebacterium infection; the patient had a favorable outcome of hepatic IPL after appropriate antibiotic therapy initiation. Our findings therefore confirm that antibiotic therapy may be effective in patients with hepatic IPL associated with underlying infections, avoiding unnecessary surgery. Our data also indicate that when hepatic IPL is observed, a complete clinical evaluation, including gynecological evaluation, should be systematically performed.

Adult↗
PubMed1985

[Effect of ultraviolet-irradiated autologous blood on the biochemical indices of sheep with a Corynebacterium infection].

Twelve sheep were used in two groups of six animals each (a control and a test one). Both control and test animals were infected with a 24-hour broth culture of Corynebacterium pyogenes. The infection was followed up in the course of five days after which the animals of both groups were subjected to autohemotransfusion, whereas the blood transfused with the controls was not treated, and the blood transfused with the test animals was treated with ultra violet rays in vitro. Following the transfusion of both untreated and treated blood the amount of blood sugar rose, it reaching higher levels in the case UV-treated blood. There were changes in the total protein and the protein fractions induced by the Corynebacterial infection, however, the initial levels were more rapidly restored in the case of transfusing UV-treated blood. With autohemotransfusion the values of glutamate-oxalacetate transaminase and glutamate-pyruvate transaminase in all animals dropped. The change was more rapidly and more strongly expressed with the transfusion of UV-treated blood.

Alanine Transaminase↗
PubMed1982

[Clinical aspects and pathomorphology of Corynebacterium infection in cattle].

Clinical, paraclinical, and morphological investigations were carried out with a total of 12 cattle (9 calves and 3 cows) with an induced suppurative surgical infection caused by two strains of Corynebacterium pyogenes. It was established that such an experimental infection in cattle clinically ran a chronic course, involving predominantly the urinary and the digestive system as well as the joints. Morphologically, the infection was manifested as a chronic septicopyemia, with purulent nephritis and pyelonephritis, cystitis, splenitis, hepatitis, valvular meningoencephalitis, and absceses in various tissues and organs.

Animals↗
PubMed1985

[Biochemical changes in the blood of sheep with experimental Corynebacterium infection].

Investigations were carried out with 24 sheep divided into two groups of twelve animals. The first group were infected via the lateral recessus of the tarsal joint with 2 cm3 of a 24-hour broth culture of Corynebacterium pyogenes, and the second one were infected i/v with 3 cm3 of the same culture. The changes in the total protein, protein fractions, and blood electrolites in the blood were followed up. It was found that the infection of Corynebacterium pyogenes affected the total reactivation of the animals and led to immunobiologic reconstruction changes. There were hyperproteinemia which depended on the route of infection as well as the severity of its course, and hyperglobulinemia which was "at the expense of' blood albumin. Noticed were also hypercalcemia, hyperpotassemia, and lower sodium and phosphorus levels.

Animals↗
PubMed1995

Total knee arthroplasty complicated by Corynebacterium jeikeium infection.

Corynebacterium jeikeium is a slow-growing multiresistant micro-organism. It causes serious opportunistic infections in patients with long hospital stays who receive broad-spectrum antibiotics. It can be isolated from blood and other sites in neutropenic, immunosuppressed bone marrow recipients and in patients with indwelling catheters. Cases of infection related to bone and joint replacements are rare. This case is the first where Corynebacterium jeikeium has been isolated from an infected knee following total knee arthroplasty.

Aged↗
PubMed1984

[Clinical and hematological studies in experimental Corynebacterium infection in sheep].

Investigation were carried out with 24 sheep divided into groups of 12 animals each. The first group was subjected to the intrajoint infection via the lateral recess of the tarsum, using 2 cm3 of a 24-hour broth culture of Corynebacterium pyogenes for each animal, and the second one--to the i/v injection of 2 to 4 cm3 of the same broth culture. The clinical state and the morphologic changes in the blood were followed up in the course of 28 days. It was found that with such experimental suppurative surgical infection, caused by Corynebacterium pyogenes, there set in changes in the body temperature, and the pulse and respiration rates regardless of the route of infection. Both the haemoglobin and the erythrocyte count dropped, and the erythrocyte sedimentation rate rose, and the latter was found to be due to the change in the total erythrocyte count. The intrajoint infection of the sheep led the rise of the total leukocyte count, while the i/v infection lowered it. Both test groups displayed aneosinophilia, neutrophilia, lymphopenia, and rise of the monocyte count, which depended on the way of infection and its clinical course. The suppurative surgical infection caused by intrajoint introduction of these bacteria set in at a slower rate and lasted for a longer time as against the single i/v infection.

Animals↗
PubMed1999

Fine-needle aspiration biopsy of chondroblastic osteosarcoma of the vertebral column complicated by Corynebacterium infection: a case report.

We describe a case of chondroblastic osteosarcoma of the vertebral column in a 67-yr-old male in whom the preoperative diagnosis was made by fine-needle aspiration biopsy (FNAB). This diagnosis was subsequently confirmed in the T8 corpectomy specimen. Although the smears of the aspirate revealed only occasional markedly atypical spindle-shaped nuclei, the cell block was diagnostic of malignancy. It showed a well-preserved fragment of neoplastic cartilage populated by markedly atypical hyperchromatic cells and a crushed fragment of anaplastic spindle-shaped cells surrounded by opaque collagenous matrix reminiscent of osteoid. The surgically resected specimen exhibited comparable histological features as well as colonies of gram-positive bacilli within the necrotic tumor. Culture confirmed the presence of Corynebacterium species. It is likely that these skin organisms were introduced at the time of FNAB. This case demonstrates the value of FNAB in the diagnosis of primary bone tumors and reports a rare complication of this procedure.

Aged↗
PubMed1988

The effect of selected viruses on Corynebacterium kutscheri infection in rats.

The influence of selected viral pathogens on rats that were previously infected with Corynebacterium kutscheri was investigated. A series of three separate experiments were performed to test the effect of sialodacryoadenitis virus, Sendai virus and rat virus. In each experiment, weanling rats were divided into three groups (C. kutscheri-inoculated, virus-inoculated and C. kutscheri plus virus-inoculated). Two groups were inoculated oronasally with C. kutscheri to establish subclinical infections. Two weeks later, two groups were inoculated intranasally with virus. At 5 weeks, the prevalence of C. kutscheri recovery from oral cavity and submaxillary lymph node and the prevalence of overt pseudotuberculosis was compared between treatment groups. Seroconversion of rats to C. kutscheri was measured by microagglutination and viruses by indirect immunofluorescence assays. Infection of rats with sialodacryoadenitis virus, Sendai virus or rat virus had no discernable effect on C. kutscheri-infected rats.

Animals↗
PubMed1994

New infection with Corynebacterium pseudotuberculosis reduces wool production.

The effect of natural Corynebacterium pseudotuberculosis infection on wool production and quality in sheep was examined in light of evidence that artificial C pseudotuberculosis infection causes wool production loss. A toxin ELISA was used to identify sheep that had been infected with C pseudotuberculosis. Greasy and clean fleece weights and fibre diameter were compared in infected and uninfected sheep. C pseudotuberculosis infection caused a 3.8 to 4.8% decrease in greasy wool production and a 4.1 to 6.6% decrease in clean wool production. C pseudotuberculosis infection did not affect fibre diameter. The effects of caseous lymphadenitis (the disease caused by C pseudotuberculosis infection) cause an annual loss of about $17 million in wool production to the Australian wool industry.

Abattoirs↗
PubMed1998

Phospholipase D-neutralization in serodiagnosis of Arcanobacterium haemolyticum and Corynebacterium pseudotuberculosis infections.

Phospholipase D (PLD) neutralization was used to examine sera of humans (n = 40) with a spontaneous infection by Arcanobacterium haemolyticum, sheep and goats (n = 76 and 79 respectively) with a spontaneous infection by Corynebacterium pseudotuberculosis, mice (n = 26) experimentally immunized with PLD from A. haemolyticum (PLD-A) and mice (n = 28) experimentally immunized with PLD from C. pseudotuberculosis (PLD-C). PLD-A and PLD-C were also used as neutralizing antigens. A positive result of neutralization was due to an inhibition of the haemolytic synergism with the equi factor from Rhodococcus equi. The titres of sera neutralizing the homologous PLD were always significantly higher than those neutralizing the heterologous PLD. The proportion of sera that were able to neutralize the homologous PLD in sheep, goats and mice immunized with PLD-A significantly exceeded the proportion of sera that neutralized the heterologous PLD. The antigenic properties of PLD-A and PLD-C were similar but not identical.

Actinomycetales↗
PubMed1993

[Differences in susceptibility of mice among various strains to oral infection with Corynebacterium kutscheri].

Differences in susceptibility of female mice among 10 strains to Corynebacterium kutscheri infection were studied pathologically and bacteriologically. Twenty mice of each strain were inoculated orally with 4 x 10(5.0) CFU of the bacteria. The gross lesions were observed in 60.0% of BALB/c-nu/nu mice, 25.0% of CBA/N mice, 10.0% of MPS mice, and 5.0% of A/J and C3H/He mice, while BALB/cCr, C57BL/6Cr, B10.BR/SgSn, ddY and ICR mice showed neither clinical signs nor gross lesions. Six BALB/c-nu/nu, two CBA/N and one MPS mice died within 15 days after inoculation. C. kutscheri was recovered from 95.0% of BALB/c-nu/nu mice, followed by 75.0% of A/J mice, 65.0% of CBA/N mice, 55.0% of MPS and BALB/cCr mice, and 30% of C3H/He mice. On the other hand, from C57BL/6Cr, B10.BR/SgSn and ddY mice, the bacteria were recovered at less than 15.0% of the mice. No bacteria were recovered from ICR mice. C. kutscheri colonized most frequently in the cecum, colon and rectum. Number of mice having agglutinating antibodies were less than 20% and their antibody titers ranged from 1:10 to 1:80. These results indicated that there were differences in susceptibility of mice among the strains to oral infection of C. kutscheri. Namely, BALB/c-nu/nu, A/J, CBA/N, MPS and BALB/cCr mice appeared to be susceptible, and C3H/He mice intermediate, while C57BL/6Cr, B10.BR/SgSn, ddY and ICR resistant. BALB/c-nu/nu mice were most susceptible and exhibited markedly severe disease by the infection.

Animals↗