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Enterotoxin-producing bacteria stools from Swedish United Nations soldiers in Cyprus.

A study was designed to establish the role of heat-labile enterotoxin producing Escherichia coli and other intestinal pathogens in diarrhoeal disease in Swedish soldiers of the United Nations' Force in Cyprus. Before leaving Sweden for Cyprus, no enteropathogens were isolated from the soldiers. The study was performed from October 1975 through January 1976 and in August 1976. Enterotoxigenic strains of E. coli, Citrobacter freundii, Enterobacter cloacae and Klebsiella pneumoniae were the intestinal pathogens most frequently isolated from the cases of diarrhoea. Such strains were found in 14 of 79 diarrhoeal cases (18%) but also in 6 of 66 (9%) of next-bed-fellow controls and in 7 of 139 (5%) of healthy Cypriotic civilians. Few other pathogens were identified in the soldiers, but 9 of 139 (6%) of the Cypriots were carriers of cysts of Giardia lamblia. The results indicate that enterotoxigenic bacteria were probably the most important cause of diarrhoea of those agents identified among the Swedish UN soldiers on Cyprus. Several soldiers were colonized with these strains without contracting diarrhoea.

Bacteria

Alpha-thalassaemia in Cyprus.

The frequency of alpha-thalassaemia in Cyprus was determined with studies of haemoglobin Bart's in 1200 Greek Cypriot and 132 Turkish Cypriot newborn babies. Of the Greek newborns, 12.4%, and of the Turkish newborns, 6.8% had raised Hb Bart's (from 0.6% to 12.9% of the total haemoglobin) suggesting that they were carriers of either alpha-thalassaemia-1 or alpha-thalassaemia-2 genes. The findings suggest that the population of Cyprus has the highest frequencies of alpha-thalassaemia among Caucasian people.

Child, Preschool

Use of corticosteroids to isolate IBR virus from cattle in Cyprus after respiratory disease and ataxia.

An outbreak of ataxia, blindness, respiratory disease and kerato-conjunctivitis occurred in October 1972 in a beef feedlot in Cyprus. Fifteen animals died and 10 that were severely ataxic were slaughtered; many animals became blind. There was no opportunity to isolate virus when the disease was active but in March and October 1973 infectious bovine rhinotracheitis (IBR) virus was isolated from cattle after they had been treated corticosteroids to stimulate virus excretion. It is probable that IBR virus caused the disease. This is the first report of the isolation of IBR virus from cattle in Cyprus.

Animals

Serum Q fever antibodies in Swedish UN soldiers in Cyprus--reflecting a domestic or foreign disease?

Swedish soldiers from 2 battalions serving in Cyprus 1975 and 1976 were tested serologically for Coxiella burnetii phase 2 complement-fixing antibodies. 2.7% were positive. Although none of the seropositive soldiers had been seriously ill abroad, the titers are considered to emanate from an infection in Cyprus as there is no evidence of domestic Q fever from a survey of 1390 Swedes.

Antibodies, Bacterial

Enterotoxin antibodies in relation to diarrhoea in Swedish soldiers in Cyprus.

The development of antibodies to Escherichia coli heat-labile enterotoxin (LT) and its relationship to diarrhoea was studied in two Swedish battalions (one in the winter, WB, and one in the summer, SB) of the United Nations Peace-keeping Force in Cyprus. Whereas only 6-15% of the soldiers had detectable levels of anti-LT antibodies in their sera before leaving Sweden, as many as 69% of the SB and 43% of the WB soldiers who developed diarrhoea in Cyprus acquired significant titres of enterotoxin antibodies in their sera (acute phase serum). During the summer, many soldiers without diarrhoea also obtained anti-LT antibodies, whereas no such response was observed in healthy soldiers during the winter. Civilian Turkish Cypriots had positive sera in high frequency (60-66%) during both study periods. Parallel titration of positive sera against E. coli LT and cholera toxin indicated that the enterotoxin-neutralizing antibodies registered were induced by bacteria producing enterotoxin identical or closely related to LT.

Antibodies, Bacterial

A report on missile injuries in Cyprus 1974.

This paper details the experiences of the Princess Mary's Royal Air Force Hospital, Akrotiri (TPMH), during the last 6 months of 1974. TPMH was at that time a small hospital (120 beds) with a clinical staff of 17 situated in the south of Cyprus (fig. 1). The series comprises 71 patients injured by bullets, shrapnel, bomb-blasts or mines, drawn from British personnel, United Nations Forces and the local Cypriot military and civilian population, resulting from the coup d'état of 15 July 1974 and the subsequent Turkish invasion and air attacks. The casualties were often severely wounded beyound the capabilities of the local hospitals. They were mostly admitted during a 2-week period, but many required multiple operations extending over the next 3 or 4 months, and altogether 119 operations were carried out on 41 patients at TPMH. The organization of the limited resources of the medical, nursing and supporting staff is outlined. The correct treatment of missile wounds is emphasized. Resuscitation, wound excision, splintage and delayed suture or grafting are essential. Minimal morbidity and mortality are gained by a practised approach to the compounded results of violence.

Adult

The 1977 outbreak of bluetongue in Cyprus.

Bluetongue outbreaks, ranging from isolated cases to widespread infections, have occurred in Cyprus in about half of the years since 1924. Serious outbreaks occurred in 1924, 1939, 1943, 1946, 1951, and 1965. Most cases occurred in September, October, November and December. The last outbreak prior to 1977 was in 1969. Virus types isolated in the past were types 3 and 4. In 1977 the outbreak was serious, affecting 13.1 per cent of 27,837 in-contact sheep; these were scattered in 303 flocks of 65 villages throughout the Government-controlled area. The virus type isolated was type 4. Culicoides were involved in bluetongue transmission in the island.

Animals

Newcastle disease in Cyprus: a review.

The first Newcastle disease epidemic in Cyprus was reported in 1949 to 1950 and between 1953 and 1959 there was a second. In November 1977 another Newcastle disease outbreak occurred. Measures implemented immediately were; quarantine of all foci of infection, destruction of diseased and in-contact birds disinfection of premises and island-wide (Government controlled) vaccination. Within a month the epidemic was brought under control. In all 47 outbreaks were recorded with the loss of about 35,000 birds. Only 2 commercial units were affected, the remaining outbreaks occurring in premises of back-yard poultry keepers. The virus was the Asiatic type.

Animals

Q fever and animal abortion in Cyprus.

Seventy-eight British soldiers stationed in the Eastern Sovereign Base Area (ESBA) in Cyprus contracted Q fever in the period December 1974 to June 1975. Pneumonia developed in 59% of cases. Of 31 patients tested, 81% had biochemical evidence of hepatitis although only one became clinically jaundiced. Three patients (4%) suffered pericarditis. Treatment with tetracycline had no apparent effect on the course of the disease. Investigation revealed an abortion epidemic involving 21 mixed flocks of sheep and goats in the south-eastern coastal region. 11 of the flocks grazed in and around the ESBA. A serological survey of 10 affected flocks, and evidence collected from previous years, indicated that the abortion epidemic was the result of infection with Coxiella burneti. Infection in the humans was almost certainly acquired by inhalation of dust from brush contaminated with rickettsial parturition products of the aborting flocks. A human serological survey revealed a number of cases of subclinical Q fever in a susceptivle military population, and an asymptomatic epidemic in a largely immune local position.

Abortion, Veterinary

Possible origin of the bluetongue epidemic in Cyprus, August 1977.

Possible origins of an epidemic of bluetongue in Cyprus in August 1977 have been analysed. First outbreaks occurred simultaneously in the south-east of the Famagusta district and on the north coast of the Kyrenia district respectively. Although the epidemic was due to type 4, which had been responsible for the previous outbreak in 1969, no evidence of persistance of virus could be found. Imports of domestic animals in the past year were not implicated since the imported cattle were introduced only to the southern part and not to the northern part of the island. Easterly, north-easterly and northerly winds during the period 11-14 August could have brought infected midges at a height of 0.5--1.5 km from Syria and Turkey, and such a movement would fit well the dates of the first outbreaks (20-25 August). Temperatures at a height of 1.5 km were 20-25 degrees C and at 0.5 km 30 35 degrees C, and with wind speeds 10-20 km h-1 the distance from Turkey and Syria would have been covered in 5-20 h. It follows that, in addition to surface winds, winds at all levels warm enough for flight should be taken into account when the possibility of disease spread by windborne midges is being assessed.

Animals

Symptom formations and character changes due to upheavals of war: examples from Cyprus.

This article offers a review of the psychoanalytic and psychiatric literature on symptom formation and individual and collective character changes triggered by war or by similarly violent civil upheaval. It is suggested that each such event should be studied by itself since many different circumstances can bring man to acts of aggression. The effects of the war on Cyprus, where group narcissism developed to compensate for hurt, constitute a case example of such focused study.

Aggression

The history of the ox warble fly in Cyprus.

The eradication of ox warble fly from Cyprus is described. Initially, the major part of the eradication consisted of dressing every bovine animal with derris at monthly intervals between December and May (inclusive), but in the final and critical stages when the level of infestation had fallen to 0-2 per cent, it was found that the most efficient and economical approach was to offer a financial reward to any stock-owner reporting the presence of warble fly.

Animals

The anti-echinococcosis campaign in Cyprus.

A national anti-echinococcosis campaign was started in 1971, in which education of the public, the control of dogs and the control of slaughter were emphasised. The campaign has already achieved almost total elimination of infection in food animals born subsequent to its initiation. Stray dogs are rare and all others are registered and examined three or four times a year. Infection in dogs has decreased by over 80 per cent (from 6-8 in 1972 to 1-1 in 1976). Legislation governing abattoir functioning and dog control is in force. Violation of legislation is penalised, although the level of awareness of the problem by the public, who co-operate willingly, does not often warrant this.

Abattoirs

Haemoglobin Lepore in Cyprus.

Structural analysis documented the presence of haemoglobin LeporeWashington (=LeporeBoston) in a Greek Cypriot family and provided further evidence that, of the various types of Lepore mutants, only one is common in the Mediterranean area. Two individuals in this family were heterozygous for both Hb Lepore and beta thalassaemia, but they exhibited striking differences in the clinical severity and course of the disease. The data illustrate that additional environmental or genetic factors play roles in determining or modifying the pathophysiological consequences of highly specific molecular defects and, thus, their ultimate clinical phenotypes.

Amino Acids