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Effect of ozone toxicity in the drinking behavior of rats.

To clarify the effects of ozone on behavior, drinking activity was observed continuously in animals exposed to ozone at concentrations of 0.2, 0.4, and 0.8 ppm for 1 wk. Drinking decreased considerably on the first day after onset of exposure. On the first day the suppression rate was calculated to be 28.1%, 69.5%, and 93.1%, for the 0.2 ppm, 0.4 ppm, and 0.8 ppm group, respectively. The suppression of drinking and recovery were dependent on the concentration of ozone.

Animals

Retrospective analysis of lifetime changes in women's drinking behavior.

Retrospective data on drinking behavior and related life experiences have been a neglected resource in research on alcohol use in the general population. Data from a 1981 national survey of women's drinking indicate the potential value of retrospective data analysis. The 1981 data provide comparative ages of onset for drinking behavior, drinking consequences, and health problems, and allow comparisons among different cohorts of women. The data also show the variability in women's lifetime drinking patterns and the time-ordering of heavy drinking in relation to onset of depression and reproductive dysfunction.

Adjustment Disorders

[Alcohol drinking behaviors--physiological and sociomedical factors].

Alcohol drinking behavior is usually studied from two perspectives, factors leading to drinking behavior and the behavioral effects of alcohol drinking. Many detailed medicolegal, pharmacological and psychiatric studies have been conducted on the behavioral effects of alcohol drinking. Few studies have considered the biological aspects of a desire for alcohol. However, these issues can not be ignored. The role of genetic, environmental and nutritional factors in alcohol preference has extensively debated. Recently, biochemical, physiological and pharmacological studies have also been performed to elucidate the mechanism of the desire for alcohol. In this study, the biological aspects of drinking behavior and alcohol preference have been studied using inbred strains of mice as an animal model on alcoholism. In addition, factors affecting drinking behavior of human beings are discussed based on the results obtained from a medico-legal study of alcohol-related cases. 1. Alcohol preference in several animal species The alcohol preference expressed as a ratio (%) of the volume taken (water and 10% (v/v) alcohol solution), was not constant in several animal species. The preference ratio was observed to be 2.7 +/- 0.7, 3.7 +/- 0.8, 22.0 +/- 19.8 and 39.6 +/- 5.4 in male inbred strains of SAMP2, DBA/2cr, B10.Br/Sg and C57BL/6J mice respectively, and 10.7 +/- 7.6, 15.9 +/- 13.6, 31.3 +/- 22.6 and 32.4 +/- 16.7 in male Donryu, DA, Wistar and Buffalo rats respectively, and 91.3 +/- 9.1 in male Golden hamster, and 2.1 +/- 0.3 in Hartley guinea pigs. Rabbits and Japanese monkeys do not demonstrate high alcohol preference. By comparison, the alcohol preference of a Japanese people was estimated to be approximately 11-35% on the basis of data obtained by questionnaire. 2. Development of alcohol dependence and withdrawal by voluntary alcohol intake in mice Eight strains of male mice, C57BL, C3H, SWM, SW, KK, KSB, KR and DBA, were offered a choice of water or 10% sake solution (sake containing 10% alcohol). Both young (3 months of age) and old (8 months of age) groups were studied simultaneously. The degree of intoxication was measured by recording the drinking behavior on a pulse recorder, by measuring gas-chromatographically the blood alcohol concentration, by taking depth electroencephalogram readings and so on. Intoxication, shown by lack of coordination such as grossly impaired gait, was observed only in the older mice of a strain with a moderate natural alcohol preference such as C3H, SWM, SW, KK and KSB.(ABSTRACT TRUNCATED AT 250 WORDS)

Alcohol Drinking

Relationship between subjective expected utility and behavior: a longitudinal study of adolescent drinking behavior.

The relationship between subjective expected utility (SEU) and the use of beer and distilled spirits by adolescents is examined. A panel design with 1339 subjects who began the study as seventh graders indicated that there were reciprocal relationships between SEU and behavior. It is concluded that SEU should be considered when attempts are made to explain adolescent drinking behavior.

Adolescent

Adolescent drinking behavior: an observational study of the influence of situational factors on adolescent drinking rates.

Adolescent drinking behavior was observed on weekend nights (9 PM until midnight) in three youth bars, three youth centers and two discos located in the most southern part of the Netherlands. Drinking rates, individual characteristics, drinking group variables and aspects of the overall drinking situation were recorded. Boys and girls appeared to differ in the variables of influence on their drinking rates. Boys were observed to drink at a higher rate on evenings with loud music, when they participated in large, all-male groups and when their (estimated) age was less than 20. Together these variables explain 24% of the variance in boys' drinking rates. Girls drank less fast when they participated in a group not buying rounds and in a drinking group of constant composition. Although analysis showed that girls' drinking rates did not vary significantly with aspects of the overall situation and individual variables, still 14% of the total variance here could be explained by the drinking group variables. These results are to some extent consistent with findings from other observational studies on drinking behavior. Most of these studies showed males in large groups to drink at the highest rates. However, only a few observational studies were aimed exclusively at young people's drinking behavior and those studies did not include aspects of the overall drinking situation.

Adolescent

Predicting Japanese American drinking behavior.

Empirical data on Japanese American drinking behavior are scarce. The present study was a random sample (N = 295) of households in Los Angeles with Japanese surnames. Japanese Americans born in the United States tended to drink less than those born in Japan. The study also observed significant gender differences in Japanese American drinking behavior which were attributed to ascribed social roles. Other demographic and social determinants of drinking were examined through two logistic regression models. The first model predicted drinking (as opposed to abstaining), while the other distinguished heavy drinkers from those who drank alcohol in more moderate amounts. Potential reference groups (e.g., parents, friends, church groups, etc.) were often significant in predicting whether and how much a Japanese American drank.

Adult

[Smoking and alcohol drinking behavior among Japanese adolescents--results from "Japan Know Your Body Study"].

The "Japan Know Your Body Study" (JKYB) is an example of collaborative activities of technology transfer carried out in Japan in several phases. The first phase is a needs assessment and data collection survey and it was administered during 1989. A survey was conducted throughout 9 prefectures in Japan with participation by 49 schools. Subjects were students in elementary, junior and senior high schools who ranged in age from 6 to 18 years. Participants, 12,892 in total, completed a survey on knowledge, attitude and behavior regarding cigarette smoking, alcohol drinking, diet, exercise and so on. The main results concerning cigarette smoking and alcohol drinking behavior were as follows: 1) The percentage of monthly male smokers rose remarkably from 8% in the third grade of junior high school to 37% in the third grade of senior high school, while that of female smokers showed a slow rise from 3% to 15%. The sex difference for smoking behavior was clear among senior high school students. 2) Smoking rates increased in proportion to the numbers of parents, siblings and friends who smoked. Above all, smoking behavior of friends was strongly related. Among senior high school students, for example, 50% of males and 46% of females who had two or more smoking friends were smokers, as compared to 5% of males and 2% of females with no smoking friends. 3) The percentage of monthly drinkers rose at a steady pace from 13% of males and 7% of females in the fifth grade of elementary schools to 59% of males and 50% of females in the third grade of senior high schools. The sex difference for alcohol drinking behavior among senior high school students, while statistically significant, was not as pronounced as that for smoking behavior. These results suggest that tobacco- and alcohol-use prevention programs should be introduced in elementary schools and those programs should include components relating to the social influences of parents, siblings and friends.

Adolescent

Drinking behavior and "alcoholism".

Drinking is viewed as a functional behavior, an active response to environmental conditions, and excessive drinking as a compromise behavior resulting from ineffectiveness in mediating goals and resolving problems.

Adaptation, Psychological

Endogenous renin-angiotensin system and drinking behavior in flounder.

High rates of drinking in seawater-adapted, compared with freshwater (FW)-adapted, flounder were associated with raised plasma chloride and osmotic concentrations. Hypotension in FW-adapted fish, after papaverine administration, gave rise to greatly elevated rates of drinking. This dipsogenic response apparently relied on activation of the endogenous renin-angiotensin system (RAS) and was abolished by simultaneous administration of the converting enzyme inhibitor, captopril. Exogenous angiotensin II was shown to be dipsogenic and vasopressor in the FW-adapted fish. The physiological importance of the activation of the RAS in the control of drinking behavior in euryhaline fish is discussed.

Animals

Circadian rhythms of feeding and drinking behavior of rats aged from 3 to 21 months.

Circadian rhythms and patterns of feeding and drinking behavior of 8 male and 8 female Long-Evans rats were followed from 3 months of age (mo) to 21 mo at 3 month intervals. Meal number, draft number and feeding events/min/meal of female rats were greater than those of male rats of the same age, while intermeal intervals, interdraft intervals and licking events/min/draft of male rats were greater than those of female rats. Sex differences of meal number, intermeal intervals and feeding events/min/meal as a group disappeared by 21 mo. Light/dark differences of meal number of both sexes, intermeal intervals of females and licking events/min/draft of males as a group also disappeared by 21 mo and difference of feeding events/min/meal disappeared by 15 and 18 mo in males and females, respectively. Occurrence of age-related change varied from 6 to 21 mo depending upon the parameter of the behavior and period (light or dark). Meal number and feeding events/min/meal showed the most clear-cut age-related changes and the decline occurred earlier and was more remarkable in males than in females. The age-related decline of patterns and the power spectrum of drinking behavior was less prominent than that of feeding behavior. These results indicate that feeding behavior is more affected by the aging process than is the drinking behavior of rats, and that male rats show more prominent aging changes than females.(ABSTRACT TRUNCATED AT 250 WORDS)

Age Factors

The relationship of pretreatment family functioning to drinking behavior during follow-up by alcoholic patients.

The relationship of alcoholics' perceptions of the pretreatment functioning of their families to drinking outcomes during an 18-month follow-up was examined. Family functioning was hypothesized to be predictive of drinking behavior, particularly in subjects with low assertion of autonomy scores. These individuals report greater dependency and attachment, and therefore might be more affected by the state of important relationships. The results indicated that with low autonomy male alcoholics, greater family dysfunction predicted significantly fewer days abstinent during Months 1-6 and 13-18 and more severe drinking episodes during the first year of the follow-up. In the high autonomy males, family dysfunction was unrelated to subsequent drinking behavior. In women, on the other hand, greater family dysfunction predicted more days abstinent in those high in autonomy and was unrelated to the drinking behavior of those low in autonomy. Implications for patient-treatment matching, differences between male and female alcoholics, and the need for additional studies of family functioning and drinking behavior in women are discussed.

Adult

Alcohol-induced facial flushing and drinking behavior in Japanese men.

The drinking behavior and alcohol-induced facial flushing of 1646 Japanese men (50.9% flushers and 48.0% nonflushers) were analyzed from questionnaires completed by their wives. The results indicate a relationship between flushing and various indices of sensitivity to alcohol and low rates of alcohol-related problems. It is proposed that alcohol-induced flushing acts as an inhibitory factor against excessive alcohol use and consequent problems due to drinking.

Adult

Change in drinking behaviors with retirement: findings from the normative aging study.

This study examines changes in drinking behaviors over an approximately 2-year span in two groups of community-dwelling men: 100 men who retired between baseline (T1) and follow-up (T2) and 316 men who remained employed. Measures were obtained from two drinking surveys conducted as part of a panel study of aging. Results indicate that the event of retirement was not a significant predictor of changes in average alcohol consumption, although retirees showed more variability between T1 and T2. Considering other binary drinking behavior variables, continuing workers and eventual retirees did not differ in the proportions moving into or out of the nondrinker status, or the situation of consuming an average of 3+ drinks/day. However, retirees by T2 were more likely to report the onset of periodic heavier drinking and problems with drinking. Evidence from this study indicates that retirement generally heralds no great shift in alcohol consumption or drinking behaviors.

Aged

A microcomputer controlled data acquisition system for research on feeding and drinking behavior in rats.

This paper describes an inexpensive, reliable computer controlled data collection system designed for the continuous monitoring of feeding and drinking behavior in rats. This system will be useful in areas of behavioral pharmacology research requiring a detailed analysis of food and fluid intake. The configuration described herein was developed for research on the "microstructure" of alcohol drinking behavior. Variables examined include: alcohol bout size, frequency and duration, interbout intervals as well as the temporal pattern of intake and its relationship to food and water consumption. Detailed analysis of behavior using this technique will enhance our ability to interpret the nature of changes in alcohol oriented behavior produced by pharmacological manipulations, aid in the development of specific hypotheses related to the regulation of alcohol drinking behavior and provide a means of testing these hypotheses.

Animals

Drinking behavior in the Colorado adoptee and twin sample.

Using a sample of adult Colorado twins, nontwin sibling pairs and pairs of unrelated adoptees reared together (N = 346), the extent of the similarity in drinking behavior within pairs was estimated. The analyses, which go beyond those possible with a study confined just to twins, suggest that some alcohol-drinking behaviors may be genetically influenced. However, the genetic variance appears to be primarily nonadditive so that it contributes more to differences than to similarities between first-degree relatives. Alternatively, although less likely, these results might suggest a special common environment for identical twins that is not present for fraternal twins, nontwin siblings or unrelated adoptees reared together. Environmental analyses indicate that both types of twins share a special family environmental similarity that is not shared by nontwin siblings. Environmental influences that affect individual differences in drinking behavior appear to contribute more to dissimilarity than to similarity. The results do not support the contention that being raised in the same family contributes substantially to similarity in characteristics of drinking behavior.

Adoption

Male Chinese drinking behavior in Los Angeles.

The purpose of this research was to identify the characteristics that distinguish male Chinese drinkers from abstainers and to clarify differences between Chinese men who drink limited amounts of alcohol and those who drink more heavily. A random sample of 218 adult Chinese men was interviewed using a schedule based on a national study of drinking behavior. The stereotype of Chinese as limited drinkers was partially supported by the data. Approximately 22% of the sample were abstainers whereas only 14% were heavy drinkers. Light drinkers were the modal category. A logistic regression model was used to evaluate the relative importance of the significant characteristics of drinkers and abstainers. Parents' drinking behavior influenced respondent's drinking behavior, and drinkers tended to like to go to parties. Chinese men with higher education were more apt to be drinkers. A second logistic regression model was used to identify the predictive variables related to the level of drinking. Chinese men who go to bars and who have friends who drink were the most likely to be heavy drinkers.

Adult