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At least 19 recordsLinked to original sources

[Erysipeloid on the islands of the Ohhotsk Sea. 2. Landscape types of the natural foci of erysipeloid].

Cases of skin (skin-artericular) form of erysipeloid were recorded in the islands of the Sea of Okhotsk. The natural foci of the causative agent of this infection were polyhostal and polyvectoral in character. The causative agent of erysipeloid exists among the animals habitating on land and sea. Mass species of animals characteristic of the island landscape served as the sources of infection. Their four landscape types (mountaineous-taiga, of sea coast and rocks, anthropurgic settlement, and of water bodies--salt and freshwater) were preliminarily distinguished by the combination of biocenological, epidemiological, and epizootological peculiarities of natural erysipeloid foci.

Animals↗

[Erysipeloid on the islands of the Sea of Okhotsk. I. The sources and vectors of the causative agent of erysipeloid].

The foci of the causative agent of erysipeloid at the islands of the Okhotsk sea were of the polyvector and polyhostal character. There were recorded 92 species of the naturally infected by the erysipeloid causative agent invertebrate inhabitants of the sea, fish, amphibia, reptilia, birds, mammals and ectoparasites of the warm-blooded animals. Gamazoid and ixodes ticks, mosquitoes, horse-flies and flees were found to be naturally infected with erysipelotrix. Ixodes persulcatus were found to be capable of infecting albino mice during blood sucking.

Animals↗

[Erysipeloid as an occupational disease of workers in shoe enterprises].

An outbreak of erysipeloid among the workers of a shoe factory is described. The spread of infection occurred due to contact with infected raw materials, which was confirmed by the isolation of Erysipelotrix rhusiopathiae from washings made from chrome and Russia leather supplied by different tanneries, as well as from casein glue. The raw materials could be additionally infected by rodents, in particular by common voles; the above-mentioned infective agent had been repeatedly isolated from these animals on the territory of this region. Leather was also infected in the process of soaking: the infective agent was isolated from the water of soaking baths. For the first time the routes of the spread of erysipeloid infection among shoe factory workers were bacteriologically confirmed. The recommended complex of sanitary, medical and antiepidemic measures led to the liquidation of the outbreak and thus proved to be effective. The authors draw the attention of epidemiologists, sanitary inspectors, occupational pathologists and heads of medical centers at shoe factories to the necessity of preventing the spread of occupational erysipeloid infection among the workers, as well as to the necessity for dermatologists, surgeons and infectionists, most frequently dealing with erysipeloid patients, to be correctly oriented in respect to this infection.

Adult↗

Time- and dose-limiting erysipeloid rash confined to areas of lymphedema following treatment with gemcitabine--a report of three cases.

Gemcitabine is a deoxycytidine analog with broad antitumor activity. Its main toxicities include myelosuppression, flu-like symptoms, bronchospasms and mild skin rash. We report three cases, in which the patients developed time- and dose-limiting erysipeloid skin reactions confined to areas of impaired lymphatic drainage after application of gemcitabine. Three patients with metastatic tumors (breast cancer, endometrial cancer and non-small cell lung cancer) received weekly infusions of gemcitabine (1000 mg/m2). All patients suffered from lymphedema of different origin and developed an erysipeloid erythema 40-48 h after chemotherapy within their preexisting lymphedema. Genuine erysipela was ruled out by laboratory tests and clinical observation. The skin reaction was repeatedly observed and faded after 14 days without specific treatment. Although the pathogenesis of the observed reaction is unclear, it is suspected that the skin symptoms were caused by gemcitabine or its metabolites. Gemcitabine is usually metabolized fast and excreted renally. In areas with impaired lymphatic drainage pharmakocinetics might be altered: inactivation happens slower and the drug might accumulate in the s.c. and cutaneous tissue, thus increasing local toxicity. Clinical judgement and biochemical parameters can help to tell apart genuine erysipela and the erysipeloid reaction.

Aged↗

[Erysipelothrix rhusiopathiae--a cause of erysipeloid and endocarditis].

Erysipelothrix rhusiopathiae is widespread among many species of animals including fish. Erysipeloid is the most common infection caused by this bacterium in man; systemic infection, with endocarditis, is rare. Most of the affected patients risk exposure to the organism at work. Two patients with E. rhusiopathiae infections are described; one with erysipeloid after slaughtering a deer, the other with fatal endocarditis after gutting an eel. Erysipeloid may be confused with "seal finger", but this disease probably has a different microbial etiology and requires different antibiotic treatment.

Aged↗

A spectrum of inflammatory metastasis to skin via lymphatics: three cases of carcinoma erysipeloides.

We report a case in which carcinoma erysipeloides was the first sign of the primary malignancy in a patient with a rare form of prostate carcinoma (mixed adenosquamous type) and two cases in which carcinoma erysipeloides was a marker of tumor recurrence in two patients with breast carcinoma. The value of recognizing the distinctive inflammatory manifestation of carcinoma erysipeloides and the significance of dermal lymphatic involvement in this form of skin metastasis are discussed.

Adult↗

Gemcitabine-induced erysipeloid skin lesions in a patient with malignant mesothelioma.

Gemcitabine is a nucleoside analogue that has shown to have antineoplastic activity in different solid tumours (lung, pancreas, bladder, colon, ovarian, and breast cancer) and malignant mesothelioma. The toxic effects of gemcitabine include myelosuppression, flu-like syndrome, altered liver function tests, bronchospasm, rash, itching, and fever. However, gemcitabine-induced erysipeloid skin reaction was reported in a small number of patients with previous history of radiotherapy or lymphedema. We reported a male patient who developed erysipeloid skin reaction following gemcitabine treatment in the absence of radiotherapy and lymphedema.

Antimetabolites, Antineoplastic↗

[On the dermal form of erysipeloid in slaughter house workmen (author's transl)].

We described the incidence and clinical course of the dermal form of erysipeloid in 125 workmen of a central slaughter-house in Bukarest. The highest frequency of the illness was observed in summer and autumn (83 cases), especially in the group aged 21 to 50 years (96 cases). Most of the cases of erysipeloid are occupationally acquired by various persons engaged in handling meat, often butchers and workmen in meat, skin, and bone processing factories. The most frequent localisation of the process was at the index fingers and thumbs of both hands.

Abattoirs↗

[Cutaneous manifestations of erysipeloid septicemia].

BACKGROUND: Rouget du porc, or swine erysipelas, usually occurs in man as Rosenbach's erysipeloid. Septicemic forms are more uncommon and can be associated with dermal involvement far from the site of inoculation. We report a case in a patient given corticosteroid therapy for systematic lupus. CASE REPORT: A 50-year-old farmer was seen with fever, infiltrative erythema of the long finger and dorsal lesions on the ring finger which developed after a skin lesions caused by a duck. The diagnosis of septicemic rouget du porc was made after isolating the germ from blood cultures. There was no associated endocarditis. Fever and skin lesions totally regressed after treatment with ceftriaxone. DISCUSSION: The diagnosis of erysipeloid was supported by epidemiologic arguments and characteristic clinical features. The corticosteroid therapy was probably a favoring factor for development of septicemia. Positive diagnosis is usually obtained from blood culture but the germ can be isolated from skin biopsies at the site of inoculation. Our patient was free of endocarditis which should always be suspected. Endocarditis is frequent and often fatal. Intravenous high-dose penicillin G is recommanded treatment.

Animals↗

Erysipeloid infection in a sheep farmer with coexisting orf.

Erysipeloid is a rarely reported zoonotic infection caused by Erysipelothrix rhusiopathiae. We report a case of coexisting erysipeloid and orf infections in a sheep farmer, an association not previously recorded to our knowledge.

Administration, Oral↗

Carcinoma erysipeloides associated with anaplastic thyroid carcinoma.

Cutaneous metastases from carcinoma of the thyroid gland are rare and carcinoma erysipeloides is even rarer. We present the clinical, histological, and immunohistochemical features of inflammatory erysipeloid metastases arising from an anaplastic carcinoma of the thyroid gland. In this case the anaplastic carcinoma probably transformed from a pre-existing, long-standing papillary carcinoma of the thyroid gland. Although visible inflammation is a hallmark of many benign skin disorders, it is not commonly present in cutaneous malignant metastases. As a result, the significance of a marked inflammatory changes in association with metastatic skin disease may not be recognized. Dermatologists need to be aware of the potential for inflammatory manifestations in cutaneous metastases from a thyroid carcinoma.

Aged↗

[A case of recurrent breast cancer with carcinoma erysipeloides responding to sequential therapy with docetaxel (TXT) and doxifluridine (5'-DFUR) accompanied by leucovorin (LV)].

A left radical mastectomy was performed on a 53-year-old woman, diagnosed with left inflammatory breast cancer, after local arterial chemotherapy with cyclophosphamide (CPA), doxorubicin and 5-fluorouracil (5-FU). Adjuvant therapy was added with irradiation and ECF. Four months after the operation, a red eruption was detected on the left upper chest wall. The lesion was diagnosed by skin biopsy as a recurrent breast cancer with carcinoma erysipeloides. Tumor marker levels suggested the recurrent cancer was ECF resistant, so we changed the chemotherapy regime to a single dose of TXT. Although tumor marker levels and the skin eruptions improved at the beginning of the therapy, pleuritis carcinomatosa was found. We changed the regime again to a continuous dose of 5'-DFUR and LV for day 1 to 7. With this regime the clinical symptoms improved, and 2 courses of this modified FL therapy were carried out. After the therapy, the tumor seemed resistant to this modified FL therapy. Therefore, we tried a sequential therapy with TXT and the modified FL, which induced an improvement in clinical symptoms. Two years later, the patient died from the breast cancer. Therefore, we conclude that the sequential therapy may be beneficial in managing untreatable carcinoma erysipeloides of recurrent breast cancer.

Antineoplastic Agents, Phytogenic↗

[Inflammatory type cutaneous metastasis of bladder neoplasm: erysipeloid carcinoma].

BACKGROUND: Skin metastasis from transitional cell carcinoma of the urinary bladder is quite uncommon. Especially, the inflammatory type of skin metastasis with features of carcinoma erysipeloid is a rare event. CASE REPORT: A 65-year-old man with bladder carcinoma who underwent radical cystectomy developed 6 months later red to violaceous papules, indurated plaques and edema in the perigenital area. The initial presumptive diagnosis was irritative contact dermatitis and cellulitis. Histologic examination of a skin biopsy disclosed dilated lymphatic vessels filled with neoplastic cells resembling transitional cells. COMMENT: Although carcinoma erypeloid is most commonly caused by breast carcinoma, it has also been linked to other carcinomas. Dermal lymphatic involvement is an essential feature shared by cases of inflammatory carcinoma. CONCLUSIONS: Carcinoma erysipeloid may be caused by bladder carcinoma. Skin metastases are generally present in the late stages of this disease and indicate a poor outcome.

Adenocarcinoma↗

Erysipeloid.

Erysipelothrix infections have been a well-known clinical entity for over a century. Only a few cases have been studied histologically, and the agent has rarely been cultured from infected patients. We present here a case of erysipeloid of Rosenbach, in which histologic study and electron microscopy document the presence of microorganisms. We also present a complete review of the clinical and pathologic features of Erysipelothrix infections and their treatment. Our observations suggest that Erysipelothrix rhusiopathiae is capable of producing L forms that may revert to a bacterial form and produce sepsis at a later time.

Erysipeloid↗

Subacute parathion poisoning with erysipeloid-like lesion.

A case of subacute parathion poisoning with an erysipeloid-like eruption of the left index finger is reported. Laboratory investigations showed no growth of pathogenic bacteria and cholinesterase activity in the blood showed a rise 10 days after the poisoning. Further blood investigations 6 weeks later showed subnormal levels of cholinesterase activity indicating chronic parathion poisoning.

Adult↗

Erysipelas in caged laying chickens and suspected erysipeloid in animal caretakers.

Erysipelas was diagnosed in 2 succeeding caged layer flocks housed in the same building and was characterized clinically by sudden death. At necropsy, lesions comprised generalized congestion, hemorrhages in the skeletal muscles and visceral organs, and swelling of liver, spleen, and kidney with or without large irregular zones of necrosis. Focal to massive hepatic necrosis was seen histologically with minimal or no inflammatory reaction. Erysipelothrix rhusiopathiae was cultured from internal organs of affected birds in both outbreaks. Medication with penicillin in the feed controlled the mortality, but relapse occurred after cessation of medication. Two attendants who handled the dead birds in this building developed a painful localized infection of the fingers that later spread to the regional lymph node. The infection responded when antibiotic therapy for erysipeloid was initiated.

Animal Husbandry↗