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Results for “ETRYPTAMINE”

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At least 19 recordsLinked to original sources

PubMed1986

[Etryptamine, a new designer drug with a fatal effect].

Capsules with etryptamine have been commonly available on the market since the middle of 1985. Up to 1962 this CNS-stimulating, monoamine-oxidase-inhibiting drug was sold as an antidepressant (Monase). A case of fatal intoxication is reported. The exact amount of etryptamine taken several hours before death are not known, but it could have been in the range of 700 mg. This drug was detected in tissue by means of common analytical techniques (GLC, GC-MS, HPLC, TLC). Etryptamine cross-reacts with the Emit-st amphetamine assay and can also be detected in urine using these techniques. The level in postmortem blood was 1.1 mg/l. The effects the young man showed were like those known from intoxication with amphetamines, MAO inhibitors, and thymoleptics. Malignant hyperthermia is discussed as a possible cause of death. It is suggested that trade in etryptamine should be controlled.

Adult↗

PubMed1963

Influence of methodology on electroencephalographic sleep and arousal: studies with reserpine and etryptamine in rabbits.

In studies with reserpine and with etryptamine, quite opposite electroencephalographic effects were obtained when either of these two drugs was administered to rabbits prior to surgical preparation for EEG recording as opposed to the drug being given after the rabbits had been fully prepared for EEG recording. With the one method, EEG rhythms indicative of sleep were obtained, while with the other method, EEG rhythms indicative of central nervous system stimulation were obtained, although with both methods, the amount of drug, duration of drug in animal, and type of acute preparation were identical for both sets of findings. The presurgical injection procedure produced EEG results more in accordance with behavioral and biochemical findings, even though the conventional procedure is to administer the experimental drug after the animal has been prepared for EEG recording.

Animals↗

PubMed1993

Fatal intoxication involving etryptamine.

A case of fatal intoxication due to the ingestion of Etryptamine (ethyltryptamine) is reported. Toxicological findings included the following tissue distribution: blood (heart) 5.6 mg/L; urine 80.4 mg/L; vitreous 2.4 mg/L; bile 22.0 mg/L; stomach contents 52.9 mg, brain 16.2 mg/g; liver 18.3 mg/g and kidney 24.0 mg/g. Anatomic pathology showed pulmonary edema and generalized visceral congestion with some epicardial petechiae.

3,4-Methylenedioxyamphetamine↗

PubMed1963