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At least 19 recordsLinked to original sources

Serologic and experimental investigations of contagious ecthyma in Alaska.

Serologic evidence of contagious ecthyma (CE) was found in domestic sheep (Ovis aries), domestic goats (Capra hircus), Dall sheep (Ovis dalli), and musk-ox (Ovibos moschatus) in Alaska. A moose (Alces alces) calf and a caribou (Rangifer tarandus) fawn were susceptible to experimental infection and both developed antibody titers as a result. CE virus was isolated from lesions of Dall sheep which were involved in a natural outbreak of the disease.

Alaska↗

Contagious ecthyma in lambs and laboratory personnel.

Contagious ecthyma, diagnosed in three lambs, was transmitted to two researchers having direct contact with oral secretions from these lambs. Intracytoplasmic viral particles were demonstrated by electron microscopy in gingival biopsies from one lamb. Lamb to lamb transmission was most likely caused by use of a contaminated gavage feeding tube. Concern for the effects of this disease and Q fever on patients having contact with contaminated medical researchers prompted the formulation of safety guidelines to prevent potentially disastrous zoonotic disease.

Animals↗

Serologic and cross-immunity studies with contagious ecthyma and goat pox virus isolates from the western United States.

Contagious ecthyma and goat pox viruses were isolated from goats affected with papulopustular epidermal lesions. Results of in vitro serum neutralization and in vivo cross-immunity studies indicate that these contagious ecthyma and goat pox isolates from the western United States are antigenically dissimilar and that exposure or vaccination with one isolate could not be used as a method of inducing immunity to the other. Exposure to each isolate conferred immunity to re-exposure with the same agent. The serum neutralization test indicates that the severity and persistance of lesions to goat pox infection influences the nature of the antibody response to an initial exposure.

Animals↗

Contagious ecthyma in mountain goat of coastal British Columbia.

Contagious ecthyma has been reported previously from mountain goat (Oreamnos americanus) in one restricted area of eastern British Columbia. A second focus of infection is reported for mountain goat from western British Columbia. Diagnosis was based on appearance of lesions at necropsy, histopathology and demonstration of poxvirus with the electron microscope. The epizootiology of this infection in mountain goat is discussed briefly.

Animals↗

Effects of visible signs of contagious ecthyma on mass and survival of bighorn lambs.

External signs of contagious ecthyma became common in a population of Rocky Mountain bighorn sheep (Ovis canadensis) in Alberta, Canada, after it attained high density. Between 1990 and 1993, we studied effects of this disease on mass gain and survival of lambs. Prevalence and severity were independent of lamb sex. Lambs with large sores and scabs gained less mass than other lambs and were lighter the following spring as yearlings. There was no significant effect of the disease upon lamb survival, and contagious ecthyma did not appear to play a primary role on the dynamics of the study population.

Analysis of Variance↗

Attempted reactivation of contagious ecthyma in Dall sheep.

Dexamethasone was administered to 2 Dall ewes that had clinically recovered from contagious ecthyma in an attempt to reactivate contagious ecthyma in the sheep. Clinical signs of disease were not detected within 24 days after corticosteroid injection, and virus was not detected in tissues collected at necropsy.

Animals↗

Contagious ecthyma in Alaskan musk-oxen and Dall sheep.

In 1976 and 1977, a disease resembling contagious ecthyma was seen in captive musk-oxen (Ovibos moschatus) in Alaska. A similar disease occurred in 1977 in captive Dall sheep (Ovis dalli). Paravaccinia viruses were detected by electron microscopy and isolated in cell cultures from both species. Experimental inoculation in susceptible and immune domestic sheep (Ovis aries) plus fluorescent antibody tests with ecthyma-immune conjugate indicated that the isolate was contagious ecthyma virus.

Alaska↗

Clinico-pathological observations on naturally occurring contagious ecthyma in lambs in Saudi Arabia.

Typical lesions of contagious ecthyma were diagnosed in lambs four months old and infection has been confirmed by viral isolation and identification. The lambs had lower total serum protein values, haemoglobin concentration, erythrocyte counts and packed cell volume, but higher blood leukocyte counts and increased serum transaminase activity when compared to apparently healthy animals. The disease is believed to be transmitted from newly introduced goats which showed evidence of infection.

Animals↗

Atypical contagious ecthyma in a sheep after extensive cutaneous thermal injury.

An atypical case of contagious ecthyma in a wether, following severe thermal injury to the skin, is reported. Histologically, extensive verrucous growths at the edges of the burned skin were areas of severe epidermal hyperplasia and hyperkeratosis. Intracellular viral particles were present, and sections of skin were positive for ovine contagious ecthyma virus by a fluorescent antibody test.

Animals↗

Effect of passively-acquired antibodies and vaccination on the immune response to contagious ecthyma virus.

Lambs which received colostrum from ewes vaccinated with contagious ecthyma (CE) virus and other lambs vaccinated with CE virus were compared for serum anti-CE immunoglobulin (Ig)G levels, delayed-type hypersensitivity (DTH) responses to CE viral antigen, and protective immunity to challenge with CE virus. Ewes vaccinated 3-4 weeks prior to parturition transferred CE antibody to lambs via colostrum. Although these lambs had higher levels of antibody at challenge than lambs vaccinated when 1-4 days old, only the vaccinated lambs were protected against challenge with CE virus at 1 month of age. Furthermore, the presence of colostrum-derived maternal antibody prevented an active antibody response in lambs to vaccination and/or challenge with CE virus, except where pre-inoculation titres were low. In contrast, the DTH response to CE viral antigen and induction of protective immunity by CE vaccination were not impaired by passively-acquired antibody. Actively immunised lambs could be distinguished from those only receiving passively-acquired antibody by the DTH response to heat-killed CE viral antigen.

Animals↗

Contagious ecthyma associated with myiasis in sheep.

A severe outbreak of contagious ecthyma (orf) is described in sheep in Saudi Arabia. In some of the affected sheep, the condition was highly aggravated by myiasis which appeared to have been favoured by the abundance of flies during the hot season. The outbreak is discussed in relation to the epidemiology of the disease in Saudi Arabia.

Animals↗

A severe case of contagious ecthyma in Tswana goats.

The first severe case of caprine contagious ecthyma (parapox) in Tswana goats is described from Botswana. Affected animals were indigenous adult Tswana goats. The case involved a flock of 12 goats of which 4 (33.3%) were very severely affected but none died. The lesions were confined to the head and included swollen lips, swollen submandibular lymph nodes, gingivitis, glossitis, ulceration on lip and gum mucosae and scab formation on ulcerated areas. No lesions were found on other parts of the body. This case was clinically indistinguishable from bluetongue.

Animals↗

Contagious ecthyma in bighorn sheep and mountain goat in western Canada.

Contagious ecthyma (CE) is reported in bighorn sheep (Ovis c. canadensis) from several national parks in western Canada and in moutain goat (Oreamnos americanus) from Kootenay National Park, British Columbia. (This is the first report of CE in mountain goat.) Diagnosis was based on clinical signs, histopathology, transmission experiments and the demonstration of a proxvirus with the electron microscope. The infection was transmitted from wild to domestic goat, but not to domestic sheep. Most infections, some of them severe, were found in lambs and kids. Clinical signs of disease were similar to those seen in domestic sheep and goats. General body condition was poor and animals had difficulty feeding normally. All infected herds had prolonged contact with areas where salt was provided artificially (i.e., salt blocks, highways and campgrounds). Fewer infected sheep were observed annually when salt blocks were removed from Jasper National Park.

Animals↗

Experimental contagious ecthyma in mule deer, white-tailed deer, pronghorn and wapiti.

Hand-reared mule deer fawns (Odocoileus hemionus), white-tailed deer fawns (Odocoileus virginianus), pronghorn fawns (Antilocapra americana) and wapiti calves (Cervus elaphus nelsoni) were exposed to contagious ecthyma lesion material obtained from Rocky Mountain bighorn sheep (Ovis canadensis canadensis) to determine the susceptibility and pathogenesis in these species. All four species developed mucocutaneous proliferative lesions of the oral cavity, grossly and histologically compatible with contagious ecthyma. The limited clinical responses to the virus indicated that contagious ecthyma would not seriously impact free-ranging individuals.

Animals↗