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Endoscopic electrocoagulation of actively bleeding arterial upper gastrointestinal lesions.

Emergency endoscopy to find the site of upper gastrointestinal bleeding is now accepted as the diagnostic method of choice. Endoscopic electrocoagulation in uncontrolled series has been successful in 98% of patients so treated (142 of 147). If a vessel is seen in an ulcer bed, some preliminary data would support surgical treatment. In my opinion, electrocoagulation is favored to prevent further bleeding. While some physicians have found electrocoagulation safe and effective, there are some who remain guardedly cautious. In the near future, a multicenter randomized study will begin to further assess the usefulness, effectiveness and safety of endoscopic electrocoagulation. Endoscopic electrocoagulation has opened a Pandora's box to exciting research in finding ways of treating acute upper gastrointestinal hemorrhage. Currently, electrocoagulation is the front runner.

Aged

A comparative study of electrocoagulation and tubal rings for tubal occlusion at laparoscopy.

The surgical and early postoperative complications and complaints associated with laparoscopic sterilization using electrocoagulation or tubal rings for tubal occlusion were evaluated in a comparative study. Procedures were randomly assigned to subjects (electrocoagulation to 151 subjects and tubal rings to 148 subjects). Difficulties in carrying out the sterillization procedures occurred more frequently when tubal rings were used (6.1%) than when electrocoagulation was used (2.0%). Rates of complications occurring at the time of surgery were similar for the two procedures. However, one patient in the electrocoagulation group had a bowel burn. Postoperative pelvic and abdominal pain were reported by a significantly higher proportion of the tubal ring cases (32.0%) than electrocoagulation cases (19.4%). It appears that although the incidence of surgical difficulties and pain may be somewhat more frequent with the tubal ring, the avoidance of such potentially serious complications as bowel burns may make femal sterilization by the tubal ring method preferable.

Electrocoagulation

Endoscopic electrocoagulation of upper gastrointestinal hemorrhage.

Endoscopic electrocoagulation was performed on 40 occasions for 38 patients with bleeding gastrointestinal lesions. Cessation of bleeding was achieved in 95%. Fifteen gastric ulcers, 14 duodenal ulcers, six Mallory-Weiss tears, one gastric varix, one hemorrhagic antral gastritis, and one esophageal ulcer were successfully electrocoagulated. Three duodenal and three gastric ulcers rebled. One duodenal ulcer and one gastric ulcer were successfully reelectrocoagulated. Failure to stop bleeding by electrocoagulation occurred in one Mallory-Weiss tear and one duodenal ulcer. There was no morbidity nor mortality attributed to endoscopic electrocoagulation. A retrospective cost analysis showed that the cost of hospitalization was less in patients treated by electrocoagulation. Patients so treated were hospitalized for a shorter duration.

Adolescent

Bleeding following tonsillectomy. A study of electrocoagulation and ligation techniques.

The efficiency of electrocoagulation (spot or zonal) and ligation for the control of bleeding was compared in 376 patients with tonsillectomy. Electrocoagulation and ligation was used in the same number of patients (188) in each group. A notable reduction in operative time (40%) was seen in cases in which spot or zonal electrocoagulation was employed. More morbidity was found in cases treated with zonal electrocoagulation. Both techniques were concluded to be equally effective in the control of bleeding following tonsillectomy.

Adolescent

Electrocoagulation diathermy for the treatment of cervical dysplasia and carcinoma in situ.

This report presents further experience in the use of electrocoagulation diathermy for the treatment of patients with cervical intraepithelial disease. By means of the colposcope it was possible to select a group of nonpregnant patients, in whom a proven noninvasive lesion was located entirely within range of the colposcope. This group, comprising 450 patients, has been treated by means of electrocoagulation diathermy, and with followup, only 28 patients have shown evidence of a residual lesion; in 8 of these the residual lesion has been eradicated subsequently by repeat diathermy treatment. Significant complications following electrocoagulation diathermy occurred in 13 patients (3%). The overall apparent cure rate for electrocoagulation diathermy was 95.4%.

Biopsy

Effect of monopolar electrocoagulation on esophagus, stomach and duodenum in dogs.

The effects of electrocoagulation on the esophagus, stomach and duodenum of mongrel dogs were studied. A commercially available electrocoagulator unit and suction electrode were used. Various dial settings and duration times were used. The total number of sites electrocoagulated was 945; histologic section of each site was prepared. A dial setting of 7 and duration of 5 seconds was safe for the canine esophagus and duodenum; for the stomach it is a dial setting of 7 and duration of 3 seconds. This information will be useful in safe application of electrocoagulation to superficial bleeding lesions in the canine esophagus, stomach and duodenum.

Animals

Laparoscopic electrocoagulation and tubal ring techniques for sterilization: a comparative study.

From August 1975 through May 1976, a comparative study was made of the effects of sterilization by standard electrocoagulation and tubal ring application techniques. The two techniques were randomly assigned to 300 patients. Results show that standard electrocoagulation and tubal ring procedures can easily and safely be performed on an outpatient basis, using local anesthetics and analgesics. Rates of surgical complications for both techniques were clinically acceptable, although tubal risk patients had a higher rate. Pain during the procedure and during the immediate recovery period was more severe for tubal ring patients. Despite the higher incidence of surgical complications and pain associated with the ring, many physicians prefer this method of sterilization because it eliminates the possibility, inherent in electrocoagulation, of inadvertent serious electrical burns.

Adult

Transcatheter electrocoagulation: a therapeutic angiographic technique for vessel occlusion.

Previous work has shown that localized electrocoagulation of blood vessels using direct current applied by catheter placed electrodes is feasible. In vitro and in vivo experiments showed that clot size and thrombosis of vessels are directly related to the product of the amount and duration of the current. Surgically created splenic hemorrhage was well controlled in 9 of 10 animals. The vessels remained permanently occluded after electrocoagulation in 8 of 9 animals. Pathological studies of all the vessels showed intimal damage at the sites of occlusion. These experiments indicate that clot formation may be a product of both intimal damage and platelet attraction to the positive electrode. The technique has advantages over embolization since no foreign material is injected and a localized clot is produced at the tip of the guidewire. There are certain disadvantages and further refinements must be developed to establish transcatheter electrocoagulation as a useful clinical technique for vessel occlusion.

Animals

A comparative study of spring-loaded clips and electrocoagulation for female sterilization.

The surgical, immediately postoperative and delayed postoperative complications and complaints associated with spring-loaded clips and electrocoagulation as techniques of tubal sterilization at laparoscopy were evaluated in a comparative study. Each of the two techniques was randomly assigned to 150 subjects. All sterilizations were performed as outpatient procedures. Subjects were followed-up during the first six weeks and again at about six months after sterilization. Rates of complications (surgical and early postoperative) were similar for the two procedures. None of the subjects required subsequent hospitalization. Technical difficulties at surgery were more frequent with the spring-loaded clip technique, principally as a result of mechnical problems with the prototype laparoscope and clip applicator. Postoperative pelvic and abdominal pain were reported by a significantly higher proportion of the patients when the spring-loaded clip was used (spring-loaded clips, 43.6%; electrocoagulation, 31.5%). At the six-month follow-up examination, rates of abnormal pelvic findings and changes in menstrual cycle formation were similar for the two techniques of tubal occlusion. There was one procedure failure among the electrocoagulation patients and none among the spring-loaded clip patients.

Adult

[Role of electrocoagulation in treatment of cancers of the rectum].

The authors describe the technics of a wide local electrocoagulation which was used in the treatment of 42 malignant tumors of the rectum: 27 adenocarcinomas and 15 malignant villous tumors. This not disabling technic, avoiding colostomy, is generally harmless even in old and poor risk patients. The mortality rate was 7 p. 100 in the adenocarcinomas series, nul in the malignant villous tumor series. The five year survival rate was 66 p. 100 in the first series and 80 p. 100 in the second. One third of the patients bearing adenocarcinomas developed recurrences, among which some were treated either by large surgery, iterative electrocoagulation, or radiotherapy after colostomy. The indications depend on the size and the site of the tumor. Electrocoagulation is found possible only for T1 or T2 tumors of the posterior and lateral walls of the rectum, provided that they are located at less than 10 cm from anus and above the sphincter.

Adenocarcinoma

Electrocoagulation of bleeding in the upper part of the gastrointestinal tract: a preliminary experimental clinical report.

Electrocoagulation of gastric or esophageal bleeding sites was evaluated in dogs using a flexible suction coagulator electrode passed through the endoscope using an electrocautery unit (Cameron-Miller model 80-7910). Acute and chronic coagulation studies in 25 dogs showed that electrocoagulation of both the esophageal and gastric mucosa was safe at an electrocautery unit setting of 5 for three to five seconds. This level of coagulation was successful in stopping bleeding created from actively bleeding esophageal and gastric mucosal defects by taking multiple large biopsy specimens. Based on these data, six patients with active bleeding gastric lesions have undergone mucosal coagulation. This successfully stopped the bleeding initially in all six patients; two patients rebled and required operative intervention within 48 hours. Further clinical evaluation is being implemented to determine its clinical role in the treatment of bleeding in the upper part of the gastrointestinal tract.

Adult

Risk of cervical cancer among an electrocoagulated population.

In Finland an organized mass screening program covers the total female population. Based on the material (429,832) from a nationwide mass screening registry it was estimated that the female population not subjected to electrocoagulation of the uterine cervix (362,511) had a sixfold risk of frankly invasive carcinoma, a fourfold risk of carcinoma in situ or dysplasia of high degree, and a twofold risk of dysplasia of low degree as compared with the female population subjected to electrocoagulation of the uterine cervix (67,321). The relative risk of cervical lesion varied by cytologic diagnosis, marital status, and Trichomonas vaginalis.

Adult

Electrocoagulation as primary therapy for rectal carcinoma.

The survival of forty-seven patients with cancer of the rectum treated by electrocoagulation is compared with thirty-seven patients treated by abdominoperineal resection. The one to ten year survival for the electrocoagulationgroup was 48 per cent and the one to eight year survival for the abdominoperineal resection group was 46 per cent. We believe that electrocoagulation when selectively applied has a place in the management of cancer of the rectum.

Adenocarcinoma

Tubal electrocoagulation under hysteroscopic control (three hundred and fifty cases).

Three hundred and fifty patients of the Family Planning Service of the Hospital De Gineco Obstetricia of the Medical Center at the Mexican Social Security Institute were treated by tubal electrocoagulation under hysteroscopic control. Our results in these patients are presented, with a follow-up period of between nine and 30 months after electrocoagulation.

Adult

Modified electrocoagulation and its possibilities in the control of gastrointestinal bleeding.

In acute experiments in the stomach of dogs electrocoagulation with simultaneous instillation of water (EHT-electrode i.e. electro-hydro-thermo-electrode) proved the most effective electrocoagulation method for controlling standardized bleeding: Optimal visibility at the bleeding site, extension of the therapeutic range as well as the avoidance of charring at the bleeding site are its major advantages. Disturbing adhesion of coagulated material on the electrode is also avoided. The electro-hydro-thermo-electrode is a cheap and portable means of controlling bleeding.

Animals

Treatment of trigeminal neuralgia in the aged by a simplified surgical approach (percutaneous electrocoagulation).

Trigeminal neuralgia can be excruciatingly painful. For aged patients, among whom trigeminal neuralgia most commonly occurs, medical therapy may often afford relief of pain. However, since this disorder is likely to become worse with increasing age, medical therapy eventually may fail because of increasing drug requirements and intolerable side effects. Major forms of surgical treatment requiring craniotomy may afford longstanding relief but are associated with significant side effects in 3-5 per cent of cases. For these reasons the authors began to test a new surgical approach, i.e., stereotaxic percutaneous electrocoagulation of the trigeminal nerve. More than 300 patients have been treated by this technique in the past five years. Successive radiofrequency lesions allow the production of a graded sensory deficit sufficient to relieve pain while preserving touch and motor function in the face. Unnecessary suffering from the severe pain of trigeminal neuralgia need not occur because of age or a debilitated condition which might ordinarily preclude surgical treatment. More than 100 patients over 65 years of age (4 of them older than 90) have been treated. Of this group, 93 per cent reported good to excellent results. Seven per cent have had some recurrent pain during the follow-up period; however, recoagulation has been required in only 5 per cent of these patients. Recoagulation may be readily performed in any patient who shows evidence of fading of the sensory deficit. The electrocoagulation technique and the results in elderly patients are discussed.

Aged

Long-term results of Gasserian ganglion electrocoagulation.

This report is a follow-up study of 315 patients under 46 years old who suffered from trigeminal neuralgia and were treated by electrocoagulation of the Gasserian ganglion. The average foll-up period was 12.7 years, the maximum 33 years. Eighty percent had a return of pain, but 96.7% ultimately attained freedom from pain after repeat electrocoagulation.

Adolescent

Electrocoagulation of pelvic endometriotic lesions with laparoscopic control.

Twenty-eight patients presenting with initial complaints of infertility or chronic pelvic pain were found to have pelvic endometriosis at laparoscopy. Destruction of the endometriotic lesions by means of electrocoagulation was performed via laparoscopy in a group of 19 patients. The remaining nine patients did not undergo such management. In the treatment group, seven of the 11 patients with chronic pain experienced complete relief of their symptoms, and six of the eight patients with infertility became pregnant postoperatively. Patients in the control group had a less favorable outcome. Only one of five patients with chronic pain had relief and one of four patients with infertility became pregnant following laparoscopy without cauterization. Electrocoagulation of pelvic endometriotic lesions under laparoscopic control appears to be satisfactory for the management of selected patients with chronic pelvic pain or infertility.

Adolescent