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Distribution of enterobiasis among nursery school children in SE Estonia and of other helminthiases in Estonia.

The occurrence of helminthiases in Estonia was under extensive observation from 1956 until 1989. Enterobiasis had remained the most prevalent helminthiasis in Estonia in the 1990s. After 1990, the number of helminthological studies decreased. This study was conducted to investigate the occurrence and possible risk factors of enterobiasis among nursery school children in Southeast Estonia. A total of 954 nursery school children were examined from 22 nursery schools in Tartu and Põlva counties in Estonia. Enterobius vermicularis infection was detected using the anal swab technique. The parents of tested children were asked to complete questionnaires so as to ascertain the potential risk factors in children's homes and in their families. The overall rate of being positive for E. vermicularis egg was 24.4%. The occurrence of enterobiasis among the examined nursery schools ranged from 11.8 to 46.2% and from 0 to 61.1% in nursery school groups. All nursery schools were infected. Children 5-8 years of age showed a significantly higher rate of being positive for E. vermicularis egg than the younger children. The overall infection rate was higher among boys and among children from larger families. The infection rate was related to washing of hands after closet use. The socioeconomic status of the family was not associated with the frequency of enterobiasis.

Anal Canal↗

Drug use in Estonia in 1994-1995: a follow-up from 1989 and comparison with two Nordic countries.

OBJECTIVE: To determine the patterns of drug use in Estonia for the years 1989 and 1994 1995, i.e. for the years before and after the pharmaceutical services in the country changed from a state monopoly to a competitive market. METHODS: The wholesale data from Estonia and the defined daily doses methodology were used. For comparison, national statistics on medicines from Finland and Sweden for the years 1994-1995 are shown. RESULTS: The general sales of drugs in Estonia decreased almost twofold in all major pharmacological groups from 1989 to 1994 and subsequently increased by 10%-30% in 1995. Substantial differences in patterns of drug use between Estonia and the two Nordic countries were observed. The amount of prescription-only medicines used in Estonia was approximately 25% of that used in Finland and Sweden. The amount of over-the-counter drugs used was 61% of that used in Finland and 58% of that used in Sweden. In the drug use patterns in Estonia, some common trends can be noted: (1) persistent traditions, such as the low use of diuretics, beta-blockers, antithrombotics and inhalant anti-asthmatic drugs; (2) changes in prescription preferences--central anti-adrenergic drugs, pyrazolones, aminoglycosides and barbiturates are being replaced by calcium channel blockers and angiotensin-converting-enzyme inhibitors, propionic acid derivatives, cephalosporins and benzodiazepines, respectively; (3) rapidly increasing use of drugs not prescribed in the 1980s, such as hormonal contraceptives, opioids and antiulcer drugs, which strongly improves the quality of pharmacotherapy in Estonia. CONCLUSION: The general trends in Estonia and the two Nordic countries are similar--the use of newer and more effective drugs is increasing and that of older ones decreasing. The changes are more rapid in Estonia than in Finland and Sweden, but, because of a short observation period, the use of newer drugs not yet prevailing. The international differences in drug utilization observed in this study may possibly be related mainly to the prescription preferences (e.g. therapeutic traditions) and less dependent on the respective health care systems (e.g. reimbursement schemes) and economic state of the country.

Drug Prescriptions↗

Births in Finland and Estonia from 1992 to 1996: convergent differences?

OBJECTIVE: To describe the differences in childbearing, in prenatal and obstetrical practices, and in perinatal health outcome in Finland and Estonia. DESIGN: Registry study using the data from the Finnish and Estonian medical birth registries for years 1992 to 1996 (in total 324,021 and 74,297 newborns, respectively). RESULTS: In 1992 the birth rates were 51 per 1,000 women aged 15 to 49 in Finland and 48 per 1,000 in Estonia. The birth rate declined in the study period in both countries, but the decline was more rapid in Estonia (-26%) than in Finland (-6%). In the same period the rates of induced abortion declined in both countries (-34% and -6%, respectively), but the rate in 1996 was still much higher in Estonia (46/1,000) than in Finland (8/1,000). Compared with Finnish mothers, Estonian mothers were younger, had fewer multiple births, less prenatal care and fewer interventions during pregnancy and delivery. The intervention rates increased in both countries during the study period, but this increase was more rapid in Estonia. The infant outcomes were poorer in Estonia, but the differences between Estonia and Finland decreased during the 1990's. CONCLUSIONS: The differences in prenatal and maternal care and in induced abortion rates have decreased between Estonia and Finland. Changes in maternal backgrounds, improved referral system for complicated pregnancies, improvements in prenatal care and in availability of appropriate equipment and technology may have caused improved maternal and infant health in Estonia, but this should be further investigated.

Abortion, Spontaneous↗

Survival of female breast cancer patients in Finland and in Estonia: stage at diagnosis important determinant of the difference between countries.

The survival experiences of female breast cancer patients diagnosed in 1968-81 in Finland and in Estonia were compared. The series consisted of 18,729 patients in Finland and 4100 in Estonia. The overall estimated 5-year relative survival rate was 67.3% in Finland and 55.9% in Estonia. The stage-adjusted 5-year relative survival rate in Estonia was 63.4% (the Finnish rates used as a standard). Older patients in Finland had much higher survival rates than older patients in Estonia. There was a clear difference in the stage distribution in Estonia between older and younger age groups, with non-localized cases occurring in older age groups. No such difference was noticed in Finland. It seems that the diagnostic lag for older women is longer in Estonia than in Finland. In Estonia older patients seek medical assistance later, or symptoms and signs of younger patients are more effectively studied.

Adult↗

The role of injection drug use in the emergence of Human Immunodeficiency Virus infection in Estonia.

OBJECTIVE: This article reviews the marked increase in human immunodeficiency virus (HIV) among injection drug users (IDU) in Estonia, a former Soviet Union republic bordering the Baltic Sea. HIV infection associated with injecting drug use has been reported worldwide. In Eastern Europe large-scale HIV epidemics have been observed from 1995 onward, after injection drug use (IDU) communities became infected. MATERIALS AND METHODS: In Estonia, surveillance of HIV infection is based on the mandatory universal notification of newly identified cases, with the same reporting principles in use throughout the last decades. By legal regulations every sample sent for HIV testing has to be coded (on the testing form) to identify the transmission category it belongs to. HIV testing was introduced in Estonia in 1987; by now over 2 million HIV tests have been performed. RESULTS: To date since 1987, 1305 cases of HIV have reported in Estonia. The incidence of HIV infections remained very low until recently, even when a considerable rise occurred in the incidence of sexually transmitted diseases, especially syphilis. Through 1999, only 96 cases of HIV had been reported nationally. Since then however, a dramatic increase has occurred. The cumulative data, including the information recorded on HIV testing forms and clinical records suggest that IDU was a factor in nearly 90% of the new HIV cases reported in year 2000. CONCLUSIONS: HIV infection appeared in Estonia much later than in many other parts of the world, so the experience from other countries that have confronted with the challenges of HIV could be of great help and importance for Estonia. The IDU related HIV infection epidemic in Estonia emphasizes an urgent need for preventive measures for IDUs as the target group.

Communicable Diseases, Emerging↗

Risk factors for coronary heart disease in 55- and 35-year-old men and women in Sweden and Estonia.

OBJECTIVE: To illustrate the geographical West-to-East division of coronary heart disease (CHD) by comparing a population from Sweden, that represents a Western country to a population from Estonia, that represents an Eastern country. Estonia has an approximately 2-4-fold higher CHD prevalence for 55-year-old women and men, respectively, than Sweden. DESIGN: Randomized screening of 35- and 55-year-old men and women in Sollentuna county, Sweden and Tartu county, Estonia. Eight hundred subjects, 100 from each cohort, were invited to participate in the study, 272 Swedes and 277 Estonians participated. SETTING: Preventive cardiology, administered by a primary health care centre at the Karolinska Hospital, Sweden and a cardiology centre at Tartu University Hospital, Estonia. MAIN OUTCOME MEASURES: The CHD risk factors (smoking, blood pressure, concentrations of lipoproteins, fibrinogen, and glucose) and certain environmental factors and attitudes related to CHD risk by questionnaires (fat-type and alcohol ingestion, self-assessed rating of CHD susceptibility). RESULTS: Of the 55-year-old men, 57% smoked in Estonia and 20% smoked in Sweden. Similar, although less pronounced differences showing higher smoking prevalence, were seen for 35-year-old Estonian men and women, whilst for 55-year-old women, less than 20% smoked in either country. Estonian 55-year-old women had lower HDL cholesterol and higher LDL cholesterol serum concentrations than Swedish 55-year-old women. Estonians reportedly ate food containing more saturated fats than Swedes, as indicated by the scale-score questionnaire. Estonians, relative to Swedes, rated their chance of developing CHD higher, and paradoxically, Estonians did to a much lesser degree believe that life style influences the risk of developing CHD. CONCLUSIONS: Elevated smoking prevalence is a striking difference between the Estonian and Swedish populations likely to explain the much higher CHD prevalence in Estonian men. The lower HDL cholesterol and higher LDL cholesterol in Estonian 55-year-old women may explain the higher CHD prevalence in Estonian women. Furthermore, the SWESTONIA CHD study (i.e. comparison between Sweden and Estonia) shows several environmental differences between the countries populations related to fat content in food, alcohol drinking patterns, and views on CHD risk and the importance of lifestyle intervention, that could contribute to the higher CHD prevalence in Estonia.

Adult↗

Comparison of incidence of IDDM in childhood between Estonia and Finland, 1980-1988.

OBJECTIVE: To compare nationwide incidence of childhood insulin-dependent diabetes mellitus (IDDM) in children aged 0-14 yr between Estonia and Finland during 1980-1988. For Estonia, which has a population genetically and linguistically related to Finland, only limited information was available. Finland has the highest incidence of IDDM in the world. RESEARCH DESIGN AND METHODS: The registration of all new cases of IDDM in Estonia was conducted by the local district pediatricians who reported every newly diagnosed diabetic patient to the Republic Endocrinology Centre. Registration of all new cases of IDDM in Finland was based on the statistics of the Social Insurance Institution, which approves free-of-charge insulin treatment for diabetes. These data were validated with one or more additional data sources. The case ascertainment rate approached 100% in both countries. RESULTS: The average yearly incidence of IDDM standardized for age for the years 1980-1988 in Estonia was approximately 33% of that in Finland. Among males it was 11.3 (95% confidence interval [CI] 10.3-12.3) per 100,000 in Estonia and 35.1 (95% CI 33.4-36.9) per 100,000 in Finland, and among females 10.1 (95% CI 9.2-11.1) per 100,000 in Estonia and 30.4 (95% CI 28.8-32.1) per 100,000 in Finland. When the two periods 1980-1982 and 1986-1988 were compared, the age-standardized incidence in Estonia remained unchanged, whereas in Finland it increased approximately 20%. CONCLUSIONS: The data between two populations who are ethnically and linguistically similar and live geographically close but in a different environment, provides further evidence that both genetic and environmental factors are contributing to the risk of IDDM.

Adolescent↗

Different labelling of obstructive airway diseases in Estonia, Finland, and Sweden.

Large differences in prevalence of asthma have been reported between westernised countries and the former Eastern European countries, and still no consensus about the reasons for the differences exists. The aim of this study was to assess diagnostic labelling of obstructive airway diseases, comparing subjects with respiratory symptoms and the diagnoses obtained in Estonia, Finland, and Sweden. A postal questionnaire was sent to population-based random samples, and 44,483 (76%) answers were obtained from the 58,661 invited in 1996. Among men, current smoking was most common in Estonia, 60%, followed by Finland, 39%, and Sweden, 28%. In all three countries, 30% of women were current smokers. Most respiratory symptoms including wheezing were most common in Estonia, also among non-smokers. The prevalence of asthma was 2.0% and chronic bronchitis 10.7% in Estonia, while the opposite was found in Sweden with an asthma prevalence of 7.8% and a chronic bronchitis prevalence of 3.1%. The pattern in Finland was similar to that of Sweden. The same differences between the three countries were found also among young subjects. The total proportion of diagnosed obstructive lung diseases in subjects with respiratory symptoms was similar, but the diagnosis of asthma was considerably more common in Finland and Sweden. Chronic bronchitis was favoured in Estonia, also among young adults irrespectively of what symptoms were present. In a multivariate model with correction for confounders, the risk (OR) for having a diagnosis of asthma was 5.65 (95% CI: 4.86-6.56) when living in Sweden, and 3.51 (95% CI: 3.00-4.12) in Finland, whereas risk for chronic bronchitis was 0.28 (0.25-0.31) and 0.22 (0.19-0.25), respectively, compared to Estonia. The study indicates differences in diagnostic practices of obstructive lung diseases between the three countries.

Adult↗

The effects of political and economic transitions on health and safety in Estonia: an Estonian-Swedish comparative study.

A general and dramatic deterioration of health in Estonia during the transition period 1990-1994 was analysed using Sweden as a comparative example. Though there were diverging trends between Estonia and Sweden in the leading cause of death, cardiovascular diseases, the gap in mortality from injury had increased most rapidly. While the injury mortality rate slightly decreased in Sweden from 1990 to 1994, it almost doubled in Estonia. In 1994, the total injury death rate for men was about 6 times higher in Estonia than in Sweden. The death rates for some types of injuries, such as alcohol intoxication and homicide, were many tenfolds higher in Estonia than in Sweden. Injury contributed the most to the widening health gap between the countries, especially in males. The mechanisms of this sudden health deterioration remain to be fully explained. It could be hypothesised that behind the traditional behavioural risk factors, the influence of socio-political factors related to economic and political reconstruction is present. A widespread risk-taking and unhealthy behaviour among Estonians can likely be partly explained as a way of coping with the distress created by the new demands of transition society. An important challenge on the way to improvement is creating the political will among policy-makers to confront the tremendous problems of controlling the factors in society that affect the population's health in Estonia.

Cardiovascular Diseases↗

Cervical cancer incidence and mortality trends in Finland and Estonia: a screened vs. an unscreened population.

Long term trends in the incidence of and mortality from invasive cervical cancer have been studied in Finland (1953-1987) and Estonia (1968-1987). The analyses are based on the data from the Finnish and Estonian Cancer Registries. An organised nationwide screening programme for cervical cancer was started in Finland in the early 1960s. In Estonia, no cytological screening programme has been introduced, and cervical malignancies are diagnosed in routine gynaecological practice. During 1968-1987, both the incidence of and mortality from cervical cancer were considerably higher in Estonia than in Finland. A decrease has taken place in the cervical cancer incidence and mortality in both countries since the mid-1960s, but whereas in Finland the decrease has been marked, in Estonia it has been less pronounced and levelled off in the 1980s. In 1987, the age-standardised (world population) incidence rate per 100,000 women was 14.0 in Estonia and 3.8 in Finland, and the age-standardised mortality rate was 6.0 and 1.6 per 100,000, respectively. The difference in the incidence of the disease in the two neighbouring countries can be partially attributed to socioeconomic factors. The main reason for the different slopes of the trend curves for cervical cancer is probably the difference in public health policies: an effective mass screening programme is being conducted in Finland but not in Estonia.

Adult↗

The dismantling of end-of-life vehicles in Estonia before putting into effect the Directive 2000/53/EC.

BACKGROUND, AIMS AND SCOPE: When joining the European Union on 1st May 2004, Estonia had to conform its legislation to the European Union legislation. In relation with that, also the treatment requirements on end-of-life vehicles proceeding from Directive 2000/53/EC of the European Parliament and of the Council of 18 September 2000 were established in Estonia for the first time. Since this area was not regulated with law beforehand, there was not any information available about it. The aim of the current survey was to ascertain the condition of scrap yards in mid 2004. In addition to that, also to identify the number of scrap yards operating in Estonia, to classify these by the number of dismantled vehicles and the potential environmental hazard, and to map the locations of car dismantling companies and evaluate their compliance with the valid requirements. METHODS: The companies that have been registered in the Commercial Registry under the activity code 503090-end-of-life vehicle dismantling were visited and visually reviewed. During the visits, the compliance of scrap yards with the existing requirements was evaluated and it was also attempted to identify how environmentally sound the dismantling technology of every scrap yard owner is. RESULTS AND DISCUSSION: Altogether, 63 scrap yards operated in Estonia by mid 2004. Twelve of them dismantled more than 100 vehicles, 13 of them 51-99 vehicles and 38 up to 50 vehicles a year. The total annual market capacity on dismantling of vehicles in Estonia is considered to be approx. 10,000 units. There are very few companies dealing only with car dismantling as the main business. Most scrap-yard owners also offer side services, e.g. haulage, car repair and maintenance. The dismantlers are interested in the selling of second-hand spare parts and scrap metal. Only one company out of 63 complied with all the requirements enacted by the relevant decision of the Estonian Minister of Environment. The rest of the scrap yards did not meet the requirements on the site on storage and treatment nor did they have the hazardous waste handling licence or the waste permit. Of the requirements established for the site for storage of end-of-life vehicles, 97% of the scrap yards were surrounded with a fence, 67% had a 24-hour guard, 45% had covered the areas with waterproof cover, but only 3% had an oil trap. Sites for treatment were in a somewhat better condition, these were mostly situated inside the buildings, where floors were covered with waterproof covers. Most of the dismantlers collected the waste oil and waste fluids into separate vessels, but there were a number of dismantlers who did not know of existence of polychlorinated biphenyls (PCB) in car air conditioning systems and the availability of mercury in sensors belonging in passenger safety systems. Proceeding from the general condition of the scrap yard, the rest of 62 scarp yards were distributed between two empirical parameters--'rather environmentally hazardous' or 'rather not environmentally hazardous'. As a matter of fact, 17% of scrap yards turned out 'rather environmentally hazardous'. CONCLUSION: Out of the scrap yards operating in Estonia, only one is compliant with the requirements set up by Directive 2000/53/EC. Another 62 appeared during the review to be sites of potential environmental pollution. In order to comply with environmental requirements and get the hazardous waste treatment license, the scrap yard owners have to invest into state-of-the-art dismantling and environment protection equipment. The main obstacle to reach the environmentally sound scrap-yard is the high investment cost and the black market for spare parts. RECOMMENDATION AND OUTLOOK: As the correction of the market in end-of-life vehicle treatment started after the adoption of Directive 2000/53/EC, the environmental authorities have to look after the ongoing correction. It is because there is still a demand for cheap spare parts and it makes it attractive to dismantle the vehicles out of scrap-yards by licensees.

Automobiles↗

The incidence and survival of acute de novo leukaemias in Estonia and in a well defined region of Western Sweden during 1982-1996: a survey of patients aged 16-64 years.

In the present work the incidence and survival of acute de novo leukaemias in two neighbouring countries, were studied retrospectively over three 5-year periods, 1982-1996. The aim was to compare the above variables, particularly with respect to political/socio-economic and environmental factors, in a well defined area of Sweden, the so-called Western Swedish Health Care Region, with Estonia. Population-wise the Western Swedish Region and Estonia are very similar; area-wise they are also well comparable. The present report covers only patients diagnosed between the ages of 16-64 years. The number of acute de novo leukaemias in the two regions was quite similar (Western Sweden n = 282 and Estonia n = 237). The age standardized incidence rate regarding total acute de novo leukaemias was slightly lower in Estonia than in Western Sweden (1.49/100,000 inhabitants/year for Estonia and 1.76 for Sweden, respectively), the difference being not statistically significant. However, the survival data for the two countries were highly different (P < 0.001). Thus, the relative survival for the total group of patients aged 16-64 years in Estonia at 1 year was 20.7% and at 5 years 3.6%, respectively. The corresponding figures for the Swedish patients were considerably higher, 65.2 and 29.4%, respectively. Further, the 5 year survival significantly (P < 0.05) increased for the Swedish patients over the 3 consecutive 5-year periods. No such improvement was recorded for the Estonian patients.

Acute Disease↗

Public health aspects of nutritional science in Estonia: status, research activities, and perspectives.

At the beginning of the 1990s Estonia was characterized by remarkable social and economic changes that also affected nutrition. An important step in the development of a Food and Nutrition policy was the adoption of a new 'Food Law' in February 1995. The publication of dietary recommendations followed recently. Scientific activities in Estonia are promoted by the 1993 established 'Estonian Society of Nutrition Researchers' (ESNS). The 'Ministry of Social Affairs' is of great importance for coordination of research into nutrition and it is making a great effort to connect Estonian nutrition research activities to European and international programs. An important field of scientific interest is concentrated on the nutrition of children and elderly people. With support of the 'Ministry of Social Affairs' a national health program for children and teenagers was established in which a school lunch project is integrated. Such a project has the aim to improve the quality of school lunches and to enable school teachers to conduct nutritional education. Within this national health program 1,900 schoolchildren were interviewed. This examination will also help to detect inequalities of the nutritional situation between social groups and to identify specific aims for a nutritional program in the different counties of Estonia. Health promoting units at schools will play an important role in realizing these aims. The nutritional supply and status of older persons will become an increasing problem. A survey of food supply with 429 subjects in social care facilities for older people was used to develop a new menu-planning system which meets the nutritional recommendations. Nutritional epidemiology is concentrated at the 'Department of Epidemiology and Biostatistics' of the 'Institute of Experimental and Clinical Medicine' in Tallinn. This department is also running the cancer registry of Estonia which has international reputation. Nutritional research of Estonia should aim to continue with the development of a new Food and Nutrition Policy. Important areas of activities will be concentrated on the training of young scientists, development of a food and nutrient data base, regular national nutrition and health surveys, and etiological-epidemiological studies on the basis of the Estonian Cancer Registry. The main targets of the 'Estonian Society of Nutrition Researchers' are directed to improve the scientific basis for research into nutrition and health.

Estonia↗

Partnership for the heart. German-Estonian health project for the treatment of congenital heart defects in Estonia.

Congenital heart defects (CHD) occur in 8 per 1000 live births. If they remain untreated, 70-80% of these patients die in early childhood. With modern diagnostic and treatment procedures, 90% of these patients reach adulthood. Within 8 years following reunification of Germany, it was possible to improve treatment for CHD in former East Germany to West German standards. Based on the experience gained in this process, a plan for improvement of care of Estonian patients with CHD was developed and implemented in the German-Estonian project, "Partnership for the Heart". The main elements of the project were (1) the training of Estonian physicians in Germany, (2) training courses conducted by German and Estonian specialists in Estonia and (3) use of telemedicine for consultation on a continuous basis. During the project 15 Estonian patients underwent cardiac surgery and/or catheter interventions performed by a joint team of German and Estonian specialists. The infant mortality due to CHD in Estonia fell by 28% during the project period. Key techniques of cardiac surgery are now being employed in Estonia without outside support, indicating the success of the training program and the long-term improvements to cardiac health care in Estonia. The total project costs were 314,252 Euro (euro), which is 50% lower than the estimated cost of treating the 15 patients abroad in Western Europe. The structure of "Partnership for the Heart" and the modified self-sufficiency model of medical care have not only produced results for Estonia but can be taken as a template for future bilateral health projects with other transition countries and for other fields of medical specialisation, and thus might aid a European health policy.

Adolescent↗

Determinants of daily smoking in Estonia, Latvia, Lithuania, and Finland in 1994-2002.

AIMS: To investigate time trends in the smoking prevalence and the sociodemographic and psychosocial background of smoking in the Baltic countries in comparison with Finland during 1994-2002. METHODS: Differences in daily smoking according to age, education, urbanization, and psychological distress in the Baltic countries and Finland were studied using postal surveys in 1994, 1996, 1998, 2000, and 2002 among adults (20-64 years old) in Estonia (n = 6,271), Latvia (n = 6,106), Lithuania (n = 9,824), and Finland (n = 15,764). RESULTS: In 1994, 1996, 1998, 2000, and 2002 the prevalence of smoking in Estonia, Latvia, Lithuania, and Finland was 47%, 54%, 46%, and 29% among men, and 21%, 19%, 11%, and 19% among women, respectively. Smoking increased among Lithuanian women from 6% in 1994 to 13% in 2002, but decreased among Estonian men and women. Smoking was generally more common among younger individuals, the less educated, and people with distress in all four countries. The odds ratios for smoking for those with low education compared with those with high education were 2.18 (1.69-2.81), 3.32 (2.55-4.31), 2.20 (1.79-2.70) and 2.80 (2.40-3.27) in men, and 1.90 (1.42-2.52). 3.09 (2.28-4.18), 0.86 (0.59-1.26), and 3.00 (2.53-3.55) in women, in Estonia, Latvia, Lithuania, and Finland, respectively. There were indications of increasing educational differences in Latvian men. Smoking was less common among rural women in all countries except Estonia. CONCLUSIONS: Estonia, Latvia, and Finland show characteristics of the "mature" phase of a smoking epidemic, and smoking may not increase in these countries. In Lithuanian women smoking may increase. Smoking may be increasingly unequally distributed in the future in all the studied countries.

Adult↗

Epidemiology of HIV in Estonia.

The aim of this study was to report on the epidemiology of HIV infection in Estonia and to molecularly characterize Estonian HIV-1 variants. Epidemiological data were obtained from the Estonian National HIV/AIDS Database. In 1995-1996 blood samples were collected from 54 of the 65 HIV-infected individuals that had been diagnosed at that time. The V3 domain of the env gene was directly sequenced from peripheral blood mononuclear cells of 49 of these 54 individuals and the sequences used for phylogenetic analyses. At the end of 1999 Estonia reported 96 diagnosed HIV cases; 46 (48%) were homosexual or bisexual men and 31 (32%) were presumed to have been infected heterosexually. Importantly, only four individuals were likely to have become infected through intravenous drug use. Forty-three individuals (45%) were presumed to have been infected outside of Estonia, whereas 38 (40%) were likely to have become infected in Estonia. As expected, a majority of the investigated individuals (80%) were found to carry subtype B virus. Infections with subtypes A, C, D, G, and CRF02_AG were also documented. The dominance of subtype B was restricted to homosexual and bisexual men. Thus, subtype B infections were documented in 33 of 34 (97%) homosexual and bisexual men, but only 6 of 15 (40%) individuals with other probable routes of infection. Thirty of the 39 subtype B sequences were joined in a tight sequence cluster that also included sequences from neighboring Russia and Lithuania. This pattern suggests a local spread of HIV-1 among homosexual and bisexual men within the region. The results from the phylogenetic analyses agreed well with other epidemiological information. In conclusion, Estonia remains a country with a low prevalence of HIV infection. A majority of the identified cases are homosexual or bisexual men, whereas HIV infection among intravenous drug users is rare. A large proportion of the homosexual and bisexual men carried closely related subtype B variants. The sequences have been deposited in GenBank under accession numbers AF286538-AF286586.

Adolescent↗

Health behaviour in Estonia, Finland and Lithuania 1994-1998. Standardized comparison.

BACKGROUND: The Finbalt Health Monitor project collects standardized information on health and health-related behavioural activity and related trends in Finland and those Baltic countries that have major public health problems with noncommunicable diseases related to lifestyle and behavioural factors. The aims of this study were to compare patterns of and trends in selected health behaviours and their socioeconomic associations in Estonia, Finland and Lithuania in the period 1994-1998. METHODS: Standardized questionnaires were posted to nationally representative samples in 1994, 1996 and 1998. Response rates varied between 62% and 83%. The total number of respondents was 3808 in Estonia, 9608 in Finland and 5716 in Lithuania. Prevalence of smoking, consumption of strong alcoholic beverages, use of vegetable oil in food preparation and leisure-time physical exercise were analysed in this study. RESULTS: No major changes in daily smoking, consumption of strong alcoholic beverages and leisure-time physical exercise emerged. However, the use of vegetable oil increased rapidly in Estonia and particularly in Lithuania (from 41% to 81%). In 1994 the prevalence of daily smoking was 53%, 28% and 44% among men and 24%, 18% and 6% among women in Estonia, Finland and Lithuania, respectively. In Lithuania the prevalence of smoking among women was notably low but increased (from 6% to 13%). The prevalence of strong alcoholic beverage consumption was similar in all countries. Leisure-time physical exercise was most common in Finland. The socioeconomic differences remained similar in all countries, unhealthy behaviours were typical among the less educated groups and men, especially in the age groups 34-49 years. CONCLUSIONS: The sociodemographic pattern of risk-related lifestyles appears to be rather similar and stable in Estonia, Finland and Lithuania. However, from the view point of possible public health implications the rapid changes in the prevalences of some behaviours are notable.

Adult↗