SEARCH · PubMed Health
Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.
Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.
Explore the source record for details and available documents.
In organ bath studies, effects of isosorbide dinitrate (ISDN), 5-isosorbide mononitrate (ISMN), a major metabolite of ISDN, and glyceryl trinitrate (GTN) on Ca-uptake into Ca-stores and Ca-release from Ca-stores were tested in the rabbit isolated femoral veins and femoral arteries. ISDN (10(-4) M) and GTN (10(-4) M) inhibited Ca-uptake in the femoral veins but not in the femoral arteries. The selectivity to the femoral veins was not observed in ISMN (10(-3) M) and GTN (3 X 10(-6) M). All the nitro compounds inhibited Ca-release from Ca-stores more effectively in the femoral veins than in the femoral arteries. The present results may explain the selectivity of the nitro compounds to the femoral veins.
In organ bath studies, the selectivity of isolated femoral vein and artery of rabbit to isosorbide dinitrate (ISDN), 5-isosorbide mononitrate (ISMN), major metabolite of ISDN, and glyceryl trinitrate (GTN) was compared. The femoral vein and artery contracted by norepinephrine were relaxed by all the nitro compounds dose-dependently. Potency order was GTN greater than ISDN greater than ISMN. The maximum inhibitory responses to the nitrocompounds and their pIC50 values (negative logarithms of doses to induce the 50% response) were greater in the femoral vein than in the femoral artery. For ISMN a 3 times greater sensitivity of femoral vein than of femoral artery was found.
We used selective graft preservation to treat an infected anastomosis of a functioning common femoral vein to common femoral vein crossover PTFE bypass performed for iliac vein occlusion. The graft was successfully salvaged by operative debridement and placement of a rectus abdominis muscle flap. With the growing interest in venous reconstructive surgery, bypass infections may be seen more frequently. This case illustrates that selective preservation of infected prosthetic grafts anastomosed to a peripheral vein may be a simple and improved method to treat these complications.
Balloon aortic dilatation is now a recognized therapy for aortic stenosis in children. Using retrograde approaches with either single or double balloons, successful dilatation can be readily achieved, but with little control of balloon position across the valve. We describe a femoral vein-femoral artery loop technique via a transseptal approach which facilitates antegrade crossing of the stenotic aortic valve and allows optimal balloon control and simultaneous pressure gradient recording during the procedure.
Subclavian vein catheterization (SVC) is not widely accepted for vascular access because it is considered more invasive than femoral vein catheterization (FVC). The use of FVC and SVC for acute vascular access was compared for 9 mo each. Complications were minimal with both, but access related hospitalizations were lower and the number of out-patient dialyses performed were higher with SVC than FVC. Complications with SVC might have been minimized by using an 18-gauge metallic needle for insertion, avoiding interdialytic infusions and using SVC for less than 4 wk.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The concentration of noradrenaline (NA) and adrenaline (A) was measured in arterial, cubital venous and femoral venous plasma in order to determine possible differences in different vascular beds in the peripheral circulation. In patients with cirrhosis, arterial plasma NA (median 2.54 nmol/l, n = 40) was significantly increased compared to controls (median 1.42 nmol/l, n = 17, p less than 0.001). Arterial plasma A was not significantly different (0.41 vs. 0.38 nmol/l). Cubital and femoral venous NA and A were positively correlated to the arterial values in both cirrhosis and controls (r = 0.86 to 0.97, p less than 0.01). In cirrhosis, median cubital venous:arterial NA ratio was significantly above unity (1.14, n = 36, p less than 0.001) as compared to unity in controls (1.00, n = 8), whereas the femoral venous:arterial NA ratio was similar in cirrhosis and controls, and significantly below unity (median 0.86 and 0.87). Cubital venous:arterial and femoral venous:arterial A ratios were significantly below unity in cirrhosis as well as in controls. The results point towards an enhanced sympathetic nervous activity in cirrhosis which may involve, among other organs, the upper limb (especially the skin of forearm and hand). To assess circulating levels of catecholamines, the importance of arterial sampling is stressed as peripheral venous samples may also reflect local factors.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The present study was designed to examine the usefulness of cannulation of the caudal caval vein through the femoral vein for the measurement of hormone concentrations in the reproductive tract in the pig. The experiment was performed on sexually pubertal gilts (Polish Large White x Polish Landrace) of a similar age (7-8 months) and body mass (100-110 kg) after two controlled subsequent estrous cycles. Six gilts in the luteal phase (10th day) of the estrous cycle were used in this experiment. The animals were subjected to a surgical procedure which included:--premedication (Combelen, i.m. 1 ml/10 kg of body mass) and than after 20-30 min general anaesthesia (Vetbutal, i.v., dose 30-40 ml) according to body mass and the symptoms observed,--insertion of cannulas (o.d. 2.2 and i.d. 1.8 mm)--one into the jugular vein and the other into the caudal caval vein through the femoral vein. In several gilts the cannulas were inserted into the caudal caval vein to a depth of 14, 18, 20, 23, 25 and 30 cm from the femoral ring. The concentrations of progesterone (P4) and testosterone (T) were analysed in samples of blood plasma from the jugular and caudal caval veins by radioimmunoassay (RIA). The largest differences in hormone concentrations between the jugular and caudal caval veins were ascertained when a cannula was inserted into the caudal caval vein to a depth of 20 cm from the femoral ring. In other cases the differences were less prominent, or no differences were observed (e.g. 14 cm for progesterone and testosterone or 18 cm for testosterone).
PURPOSE: Central venous cannulation via the common femoral vein is an important starting point for many interventions. The purpose of this study was to determine the optimum conditions for cannulation of the femoral vein and to compare these with the relative changes in the internal jugular vein. METHODS: High-resolution 2D ultrasound was utilised to determine variability of the calibre of the femoral and internal jugular veins in 10 healthy subjects. Venous diameter was assessed during the Valsalva manoeuvre and in different degrees of the Trendelenburg position. RESULTS: The Valsalva manoeuvre significantly increased the size of the femoral and internal jugular veins. There was a relatively greater increase in femoral vein diameter when compared with the internal jugular vein of 40 and 29%, respectively. Changes in body inclination (Trendelenburg position) did not significantly alter the luminal diameter of the femoral vein. However, it significantly increased internal jugular vein diameter. CONCLUSIONS: Femoral vein cannulation is augmented by the Valsalva manoeuvre but not significantly altered by the gravitational position of the subject.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
We report successful replacement of infected axillofemoral bypass with a combined femoral vein and superficial femoral artery graft. The new graft was transferred through the tunnel left after infected prosthesis removal. Good early and long-term results indicate that this may be a sufficient procedure.