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At least 19 recordsLinked to original sources
PubMed1977

Epidermal-dermal tissue interactions between mutant foot skin and normal back skin: a comparison of the inductive capacities of scaleless low line and normal anterior foot dermis.

The inductive capacities of 9- to 16-day anterior foot dermis of scaleless low line and normal embryos were compared by recombining them with a common source of epidermis, i.e., 7-day normal back epidermis. Tissue recombinants were cultured as grafts to the chorioallantoic membrane (CAM). Both normal and scaleless low line dermis of 12 to 13 days of incubation began to lose their ability to elicit feather production in 7-day normal back epidermis. Normal foot dermis began to elicit scale production at 12 to 13 days, whereas scaleless low line anterior foot dermis maintained feather production at a low level. It is inferred that without being associated with scale placode formation, scaleless low line anterior foot dermis does not acquire specific inductive capacities related to the production of an outer scale surface in the overlying epidermis. Feather placodes do not function as surrogates of scale placodes. The difference between normal and scaleless low line anterior foot dermis in terms of specific inductive capacities related to scale production is interpreted as a secondary effect of the action of the scaleless allele in interfering with scale placode formation in the scaleless low line anterior foot epidermis.

Animals↗
PubMed1979

[Replacement of skin defects on the foot with dorsal foot artery pedicle island flap (author's transl)].

On the basis of four known cases, authors describe the art. dors. pedis pedicle island flap method (McCraw, Furlow) for replacement of skin defects on the foot. The pedicle of the flap is composed of the art dors. pedis, the vena comitans and the peroneal nerve. The flap is suitable for replacement of skin defects around the external or internal malleolus, on the margin of the sole and heal, over the tendon Achilles as well as on the anterior surface of the lower third leg. Vascular anatomy of the island is described and details of the technics for the formation of island are given. Beside the good vascular supply the importance of innervation is emphasized.

Adult↗
PubMed1979

Foot length--a new and potentially useful measurement in the neonate.

The foot length, occipito-frontal head circumference (OFC), crown-rump, and crown-heel length (CHL) of 123 neonates of gestational ages 26-42 weeks, were measured between 12 hours and 5 days. A gauge, designed and constructed at St Mary's Hospital, Manchester, was used to measure foot length. In term babies (37-42 weeks) who were of weights appropriate for gestational age (AGA) the scatter about the mean of foot length measurements was small (coefficient of variation = 4.5%) compared with birthweight (coefficient of variation = 12.0%). The wide range of foot length measurements in babies of different gestational ages prevented maturity being accurately estimated. The mean birthweight of term light-for-dates (LFD) babies was 30.9% lower than term AGA babies, whereas the mean foot length, OFC, and body length of LFD babies was reduced by only 4.2-8.8%. There was a positive linear correlation between foot length and other indices of body size in LFD and AGA babies of all gestational ages. However, in premature babies (less than 37 weeks) the correlation between foot length and birthweight (r = 0.95) and foot length and CHL (r = 0.96) was pronounced. The 95% confidence limits of the regression lines were +/- 327 g and +/- 2.3 cm respectively. Birthweight and CHL of premature babies can therefore be estimated from a measurement of foot length that is performed simply and rapidly. Measurements of foot length are valuable in premature babies who are too ill at birth for conventional anthropometric measurements to be made, and in whom such measurements cannot be carried out subsequently because of the encumbrance of the incubator and intensive care apparatus. Drug dosages and intravenous fluid requirements based on body weight or surface area can be indirectly calculated from a measurement of foot length.

Anthropometry↗
PubMed1979

Gross and histological abnormalities of the talus in congenital club foot.

Gross and histological abnormalities were demonstrated in a club-foot talus from a boy with multiple congenital anomalies who died when he was nine days old. Both tali were studied, the one from the club foot and the one from the normal foot. The gross anomalies involved the smaller size of the club-foot talus and the increased medial deviation of a stunted, misshapen head and neck region. Serial histological sections of both tali allowed for a three-dimensional geometric appreciation of both bones and an assessment of the nature and extent of histological and cytological features. The ossification center of the club-foot talus was absolutely and relatively smaller than that of the normal talus. It was eccentrically positioned, being more lateral and anterior than that of the normal talus. The marked histological abnormalities seen in the head and neck region of the club-foot talus involved extensive breaching of the endochondral sequence by vessels. The posterior aspect of the endochondral sequence and ossification center was normal. The extra-osseous and intra-osseous blood supply of the two tali was normal with the exception of the increased and irregular breaching of the endochondral sequence in the club-foot talus. This study demonstrates histological abnormalities in the head and neck region of the club-foot talus, which was most abnormal grossly. The eccentric position of the secondary ossification center as well as its related vascular abnormalities do not support a theory of developmental arrest of the talus but appear sufficiently abnormal to support the theory of a primary defect in the cartilage anlage. Clinically, one must bear in mind that early open reduction of the talocalcaneal navicular joint in a foot such as this would have served to reposition the navicular onto a talus that still was structurally abnormal.

Clubfoot↗
PubMed2026

Foot exercise plus education versus brief advice for the treatment of plantar heel pain (FEET Trial): a feasibility randomised controlled trial.

BACKGROUND: Despite foot muscle strengthening being a target of exercise interventions for plantar heel pain (PHP) no study has measured foot muscle outcomes, and existing research is limited by a lack of control (no treatment) comparisons. OBJECTIVES: To determine the feasibility of conducting a randomised controlled trial and investigate the acceptability and credibility of comprehensive progressive foot exercise and education compared to brief advice for PHP. DESIGN: Randomised parallel group feasibility trial. METHOD: People with PHP were randomised (1:1 concealed allocation) to receive either foot exercise plus education or brief advice for twelve weeks. Primary outcomes included willingness to enrol, recruitment rate, adherence, logbook completion, dropout rate, early withdrawal reasons, adverse events, additional treatments sought, and credibility/expectancy. RESULTS: Twenty people with PHP (16 women; age 50 ± 9 years; body mass index = 30.7 ± 4.6 kg/m2) were recruited over 15 weeks (1.3 participants per week). Primary outcomes were willingness to enrol (80%), adherence (physiotherapy sessions attended: foot exercise plus education 85%, brief advice 100%; home exercise program: 62% daily sessions completed, 72% thrice weekly sessions completed), logbook completion (foot exercise plus education 75%, brief advice 90%), dropout rate (15%), and additional treatments sought (69%). There were no intervention-related adverse events, and credibility scores were higher for foot exercise plus education. CONCLUSIONS: This study confirms feasibility and acceptability of a protocol comparing foot exercise plus education with brief advice in individuals with PHP, generating key insights to inform future trial design.

Humans↗
PubMed1979

Calcaneocuboid joint and stability of the longitudinal arch of the foot at high and low gear push off.

The calcaneocuboid joint was studied in ligamentous specimens of ten human feet, and in skeletons of two gorillas (Gorilla gorilla beringei), six chimpanzees (Pan troglodytes), three orangutans (Pongo pygmaeus) and 25 human feet. The movement of the transverse tarsal joint was further studied in a living foot on a walk-way with a glass plate inserted, and with an underlying mirror. In man the joint is shaped as an asymmetrical sector of one end of an hour-glass shaped surface of revolution with its main axis oriented longitudinally in the foot. The calcaneocuboid joint becomes close packed by a pronation of the forefoot in relation to the hind foot because of a congruency between the joint surfaces obtained in this position and because the calcaneus overhangs the cuboid dorsally and stops the movement. At low gear push off the foot is inverted and the calcaneocuboid joint loose packed. The stresses are absorbed across the fibular, postaxial border of the foot. At high high gear push off there is a functional pronation of the forefoot with a stabilization of the transverse tarsal joint and a more effective tightening of the plantar aponeurosis. The foot becomes a rigid lever for propulsion. In contrast to the human condition, the anthropoid calcaneus has an anteromedial extension associated with symmetry of the calcaneocuboid joint. The calcaneus does not overhang the cuboid and there appears to be no close packed position. Correspondingly, the anthropoid foot has a mid-tarsal break at each push off in addition to the metatarsophalangeal break.

Animals↗
PubMed1976

[Combined vaccines including 1 or several anti-foot-and-mouth valences].

Combined vaccines are used for many human and animal diseases. However, we have very few examples of combinations containing anti-foot-and-mouth valence which would allow easy immunization against differnet diseases without additional handling. Until now foot-and-mouth vaccination has been applied simultaneously with anti-brucellic vaccination (Baldoni, Renoux), andi-anthrax (Nobili) and vaccination against swine fever and Aujeszky's disease (Lysenko). During the last ten years we have particularly studied the association of anti-foot-and-mouth disease vaccines with anti-brucella and anti-rabies vaccines. We have shown the possiblity of combining these different antigens, either in classical aqueous vaccines in aluminum hydroxide, or in emulsified vaccines containing oily adjuvants. The anti-brucella valences may be agglutinogenic (H 38) or non-agglutinogenic (MacEwen 45/20). The combined vaccines "rabies + foot-and-mouth disease" and "brucellosis + foot-and-mouth disease" can be produced on an industrial scale. For many years millions of animals have been successfully vaccinated in France by means of a combined "rabies + foot-and-mouth disease" vaccine.

Adjuvants, Immunologic↗
PubMed1979

Blood donation and the foot-in-the-door technique: a limiting case.

Three experiments testing the effectiveness of the foot-in-the-door technique for recruiting blood donors consistently failed to demonstrate that this procedure influences either verbal or behavioral compliance, suggesting that the generality of the foot-in-the-door phenomenon is limited. Experiment 1 attempted to demonstrate that an earlier failure of this technique was due to poor operationalization rather than to the magnitude of the critical request or to the invalidity of the phenomenon, but it failed to do so. Experiment 2, designed to more closely resemble other foot-in-the-door studies by using telephone contacts and an initial request for persons to answer questions, was conducted to examine other possible explanations for the two previous failures. This experiment also failed to show any foot-in-the-door effect. Experiment 3 was a conceptual replication of Experiment 2 but used personal contacts. One apparent foot-in-the-door effect emerged in this case, but it was more likely due to a factor other than the experimental treatment. It is concluded that although the foot-in-the-door procedure may indeed influence verbal compliance with requests for minimal forms of aid, it probably will not significantly affect people's willingness to comply with more substantial requests involving behaviors that are psychologically costly to perform.

Adult↗
PubMedDate not supplied

Foot orthotic devices to modify selected aspects of lower extremity mechanics.

Excessive foot pronation has been speculated to be a cause of leg and foot problems among runners. Foot orthotic devices are often used to modify this condition. Examination of the records of 180 patients treated for various running injuries showed that 83 individuals (46%) were prescribed orthotic devices and that 65 of these runners (78%) were able to return to their previous running programs. In order to assess further the effects of this type of orthotic device, six runners were selected from this group and filmed using two cameras (200 frames/sec) under three conditions: (1) barefoot, (2) regular shoe, and (3) regular shoe plus orthotic device. Both the period of pronation and the amount of maximum pronation were significantly reduced by using the foot orthotic device. The data support the conclusion that foot orthotic devices can be successfully used to modify selected aspects of lower extremity mechanics during the support phase of running.

Ankle↗
PubMed1978

A phlebographic study of the incidence and significance of venous thrombosis in the foot.

A total of 188 foot phelbograms in 100 patients with suspected venous thrombosis or pulmonary embolism were studied. Thrombus was demonstrated in 59 (31%) of the foot phlebograms. It is concluded that foot vein thrombosis is common, that it may be a source of pulmonary embolism, and that venous thrombus may start in the foot veins and spread into the calf. Foot phlebography should become part of the routine examination of patients with suspected deep venous thrombosis or pulmonary embolism.

Foot↗