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Potentially carcinogenic species emitted to the atmosphere by fossil-fueled power plants.

The identities and physicochemical characteristics of potentially carcinogenic species emitted to the atmosphere by fossil-fueled power plants are presented and discussed. It is pointed out that many so-called carcinogens are preferentially concentrated on the surface of respirable fly ash particles thus enabling them to come into intimate contact with lung tissues when inhaled. Relatively little information is available about the identities of particulate polycyclic organic compounds whose emission from coal fired power plants may well be substantially greater than hitherto supposed. The importance of chemical changes, which several species may undergo following emission (but prior to inhalation) in determining their potential carcinogenic impact, is stressed.

Air Pollutants

Beef production options and requirements for fossil fuel.

A large percentage of the feed resources used in beef production cannot be used by man or most other animals. These noncompetitive feeds could be used in different ways to increase beef production, but fossil fuel consumption by the beef industry would not be greatly reduced.

Animal Feed

Bioassay of complex mixtures derived from fossil fuels.

The conversion or processing of shale, coal, or petroleum involves elevated temperatures and altered pressures, and under these conditions polynuclear aromatic hydrocarbons are likely to form. Certain compounds of this type exhibit carcinogenic activity for a variety of organ sites in experimental animals and epidemiological evidence strongly implicates their role as carcinogens in man. It is then not unexpected that many liquid fractions derived from shale and coal are carcinogenic when subjected to bioassay. Benzo(a)pyrene, [B(a)P], is frequently considered to be an indicator substance. It is clear that when a small quantity of B(a)P is present in a fraction, the fraction will exhibit carcinogenic activity in a bioassay (mouse skin). However, it does not follow that the lack of detectable B(a)P insures that the fraction will be noncarcinogenic. Several fractions have been analyzed for their content of B(a)P and then subjected to bioassay. A method for testing complex mixtures for their carcinogenic potential is described. The carcinogenic potency of these fractions are compared to petroleum fractions.

Animals

Biomass burning contributions to Mexico City's atmospheric CO2 estimated using a multi-isotope approach.

Fossil fuel combustion dominates anthropogenic emissions worldwide; however, special attention should be addressed to biomass burning, since it is an increasingly important contributor under warmer, drier fire-weather conditions exacerbated by climate change. These emissions could impact the atmospheric composition of heavily urbanized environments. To assess the influence of biomass burning, along with fossil fuels combustion and soil and plant respiration on Mexico City's atmospheric composition, we conducted a year-long (December 2023-December 2024) isotopic monitoring of atmospheric CO2, combining radiocarbon (&#x394;14C), CO2 stable isotopes (&#x3b4;13C, &#x3b4;18O), and CO/CO2 ratios. Once defined the isotopic signatures and the characteristic CO/CO2 that describe the sources, we performed Monte Carlo simulations under two tracer modalities (&#x394;14C + CO/CO2 and &#x394;14C + CO2 stable isotopes) for source apportionment. Results show that during the dry season, particularly in March-April, atmospheric &#x394;14C values approached and overlapped background levels despite Mexico City's fossil-fuel dominance, indicating enhanced non-fossil inputs. Moreover, backward HYSPLIT trajectories supported that these elevated &#x394;14C values coincided with regional wildfire activity. Monte Carlo results attributed up to &#x223c;34 %-60 % of local CO2 to biomass burning in April, followed by March with contributions of &#x223c;31 %-49 %. Since these biomass burning figures contrast with the official emissions inventory of Mexico City metropolitan area, which assigns <1 % of total CO2 emissions to biomass burning, this study could exhibit the emissions inventory underestimation of this source, and thus, the need to reassess and incorporate top-down isotopic constraints in fire-affected urban regions.

Mexico

Atmospheric CO2 consequences of heavy dependence on coal.

Accurate and regular measurements of the concentration of CO2 in the atmosphere during the past 20 years show an accelerating increase. Although clearing of tropical forests has released large amounts of carbon to the atmosphere, evidence is strong that a major contributor is the combustion of fossil fuels. Future energy demands of the world will require extensive further exploitation of fossil fuels, and projections show that without major development of nonfossil fuel alternatives, the atmospheric concentration will double within the next 75 years. Four issues require serious attention. The developing countries will require vastly increased amounts of energy. Major efforts to develop suitable (inexpensive) nonfossil energy sources to meet at least a portion of this demand are required. The distribution of carbon released from fossil fuels and from other anthropogenic sources among the reservoirs of the carbon cycle must be better defined. Uncertainties regarding the effect of the increased concentration of CO2 in the atmosphere on global climate must be reduced. Possible political and social responses to a substantial climate change must be studied in order to more fully understand all of the implication of increased atmospheric CO2.

Air Pollution

Fertilizers for food production vs energy needs and environmental quality.

The world is experiencing an energy crisis that is restrictive to agricultural requisites production at the same time that food is becoming increasingly short on a global basis. Fertilizers are the most energy demanding of these inputs and have become very expensive and intermittently short in supply with the reduced availability of fossil fuels. They have been indicted, furthermore, as environmental pollutants due to their presumed role in eutrophication and in being a source of excessive NO3-N that may accumulate in some leaf crops and in drinking waters. Exponential growth in fossil fuel consumption cannot continue. Economies can be made in the agricultural sector, which does indeed consume substantial quantities of energy. The energy consumed in this very essential food-producing process, however, is almost insignificant compared with that involved in transport and processing of food beyond the farm and with other energy expenditures in modern society. A shift in priorities will certainly be required in adapting to the real world of the 1970s if man's first need is to be met. Economies in fertilizer use can be made by adherence to known agronomic principles. Savings in fossil fuel energy can probably be effected also in the production of N fertilizer, by far the most fossil-energy-demanding process in the realm of agriculture. Considerable research remains to be done, however, under varied climatic conditions for understanding and controlling processes by which residuals from fertilizers may become environmental pollutants. The various issues in this paper must be resolved promptly in consideration of the now-existing energy crisis and the imminent world food crisis.

Air Pollution

Medical aspects of power generation, present and future.

It can be seen that the radiation emissions of nuclear power plants are small indeed, compared to natural background radiation and other man-made sources of radiation. For example, the poulation is exposed to 100 times more radiation from television sets than from nuclear power reactors. The assumed risks to the people in this country from nuclear power reactors are also small compared to the normal risks which are tolerated in this society. The complete elimination of all hazards is a most difficult if not impossible task. If we need and desire a certain level of electrical energy, if we must choose between alternative sourves of the energy, then it is apparent that the total impact on our health from nuclear power generation of electricity, under normal operations and in consideration of catastrophic accident probabilities, is significantly less than that of continuing or increasing use of fossil fuels to generate electricity.

Abnormalities, Radiation-Induced

[Suspense-dust-, lead- and benzpyrene emissions in the city of Zurich].

Levels of particulate matter, lead and benzo(a)pyrene were measured during 1971--1976 at different monitoring stations in Zurich. Annual averages in city proper ranged between 90 and 180 microgram/m3 for particulate matter, 2 and 3 microgram/m3 for lead and between 6 and 7 ng/m3 for benzo(a)pyrene. Corresponding values for the suburbs as well as for the village of Netstal were about 1/3 to 1/2. Winter levels were higher than the summer ones at all the sites. These differences were more obvious in case of calms. Ambient concentrations of particulate matter and lead measured in the city center were similar to those measured in german cities and were in the same range as air quality standards. Primary attention should be paid to the reduction of emissions, as surveillance of space heating and incineration equipment, and the reduction of lead in fossil fuels.

Air Pollution

Structural genome variation drives adaptation of the xylose-fermenting yeast Scheffersomyces stipitis to lignocellulosic hydrolysates.

Second-generation (2G) bioethanol from lignocellulosic feedstocks is a sustainable alternative to fossil fuels. However, its production is constrained by the poor performance of industrial microbes in hydrolysates that are generated during biomass pretreatment. Scheffersomyces stipitis is a native xylose fermenting yeast and a promising platform for 2G bioethanol production, and adaptive evolution under hydrolysate stress has yielded strains with enhanced performance. However, the chromosomal basis of this adaptation is unknown. Here, we demonstrate that chromosome scale structural variation, rather than point mutations, underlies the improved phenotype of the evolved strains. By integrating long- and short-read genome sequencing, we identify two major chromosomal rearrangements in the top performing isolate: a reciprocal translocation between chromosomes 1 and 2 that disrupts the NUDIX hydrolase gene YSA1, and the formation of a mitotically stable 175&#xa0;kb minichromosome derived from chromosome 5. Functional analyses show that disruption of YSA1 enhances xylose utilisation and ethanol yield, while the minichromosome contributes to improved performance in hydrolysate conditions. These findings provide direct evidence that balanced rearrangements and minichromosome formation can be selected during prolonged stress and can generate adaptive phenotypes. Taken together, our study establishes genome reorganisation as a key driver of adaptation in S. stipitis.

Xylose

Environmental metallic carcinogens: an overview of exposure levels.

Exposure levels of the principal carcinogenic and potential carcinogenic metal and mettalloid pollutants in the environment (e.g., arsenic, beryllium, chromium, nickel, cadmium, and lead) are primarily reviewed with emphasis on their environmental sources both natural and manmade. There is a general paucity of definitive information concerning aspects of material balance and chemical transformations of these elements in various chemical forms in the environment, primarily the atmosphere. Estimates of both exposure levels and risk to populations other than industrial workers of the above metals have been in most instances quite difficult to obtain and generally speculative. The trend for the immediate future appears to be of greater exposure to these metals not only as a result of generally increased usage patterns, but also because of prospective enhanced use of fossil fuels for space heating and electricity generation.

Adult

Effects of sulfuric acid aerosol on cardiopulmonary function of dogs, sheep, and humans.

Submicronic aerosol of sulfuric acid (H2SO4) originates from the burning of fossil fuels and discharge of vapor from the automobile engine equipped with the catalytic converter. This study was conducted to determine whether brief exposure to this aerosol in high concentrations adversely affects the cardiopulmonary system. In all studies, submicronic aerosol of sodium chloride was used as a control. Anesthetized dogs that breathed H2SO4 aerosol in concentrations up to 8 mg per m3 showed no effects on respiratory resistance, static lung compliance, and functional residual capacity. A 4-hour exposure to H2SO4 aerosol (4 mg per m3) produced no significant changes in mechanics of breathing, functional residual capacity, pulmonary and systemic arterial blood pressures, cardiac output, heart rate, and arterial blood gas tensions. Conscious sheep that breathed H2SO4 aerosol in concentrations up to 14 mg per m3 for 20 min had no alteration of tracheal mucous velocity in an immediate 3-hour follow-up period or 5 to 10 days later. Conscious sheep that breathed H2SO4 aerosol (4 mg per m3) for 4 hours had no significant alteration of tracheal mucous velocity immediately and 2 hours thereafter. Both normal and asthmatic adults breathing H2SO4 aerosol in concentrations up to 1 mg per m3 for 10 min showed no significant alteration of lung volumes, distribution of ventilation, ear oximetry, dynamic mechanics of breathing, oscillation mechanics of the chest-lung system, pulmonary capillary blood flow, diffusing capacity, O2 consumption, and pulmonary tissue volume. No delayed effects in pulmonary function nor exacerbation of bronchial asthma were observe during a follow-up period of a few weeks. The present study indicates that single exposure to submicronic H2SO4 aerosol does not produce an immediate or a delayed adverse effect on cardiopulmonary function in anesthetized dogs, conscious sheep, and normal and asthmatic adults.

Aerosols

Mutagenic and carcinogenic properties of polycyclic aromatic hydrocarbons.

The rapid development of the chemical industry, combustion of fossil fuels, and smoking of tobacco have resulted in contact of the general population with benzo(a)pyrene and other carcinogenic aromatic hydrocarbons. Persons especially at risk occupationally are those engaged in thermal processing of oil shale, coal, and heavy residual petroleum. It has been shown that polycyclic aromatic hydrocarbons require metabolic activation before they can act as mutagens or carcinogens. This metabolic activation results from interaction with microsomal enzymes present in many body cells, yielding reactive epoxides which react with DNA and produce mutations in the count frame shift or participate in covalent bounding. While opinions differ regarding the relative role of these processes in mutagenesis, considerable evidence exists which links mutagenesis and carcinogenesis. Metabolites of the polycyclic aromatic hydrocarbons which are carcinogenic are usually mutagenic, which supports the hypothesis that damage to chromosomes plays an important role in carcinogenesis. These facts open the possibility to monitoring the spread of carcinogenic substances in the biosphere by relatively simple tests whose endpoint is mutagenesis.

Air Pollutants

Processing use, and characterization of shale oil products.

Oil shale is a potential source of oil that will supplement conventional sources for oil as our needs for fossil fuels begin to exceed our supplies. The resource may be mined and processed on the surface or it may be processed in situ. An overview of the potential technologies and environmental issues is presented.

Environment

The energy cost of overweight in the United States.

We have calculated the total fossil energy equivalent of the food calories saved by reducing the present degree of overweight (2.3 billion pounds for the adult United States population) to optimum body weight and the annual fossil energy reduction once all Americans reached their optimum weight. The energy saved by dieting to reach optimal weight is equivalent to 1.3 billion gallons of gasoline and the annual energy savings would more than supply the annual residential electrical demands of Boston, Chicago, San Francisco, and Washington, DC.

Adolescent

Hydrogen sulfide poisoning: review of 5 years' experience.

The workforce of Alberta, a province rich in fossil fuel, faces an increasing risk of exposure to hydrogen sulfide (H2S). Basic knowledge of the population exposed during the years 1969 to 1973 inclusive was accumulated to identify the immediate medical and management problems. Data were recorded from three sources of records: the Workers' Compensation Board of Alberta, the Alberta Hospital Services Commission and the provincial coroner's office. There were 221 cases of exposure to H2S. The overall mortality was 6%; 5% of victims were dead on arrival at hospital. Admission to hospital was required for 65% of the victims arriving at a hospital emergency room (78% of the 221). Acute problems were coma, dysequilibrium and respiratory insufficiency with pulmonary edema. Increased attention to cardiopulmonary resuscitation at the exposure site and during transportation to hospital is necessary to reduce the mortality from H2S exposure. No long-term adverse effects were apparent in the survivors.

Accidents, Occupational

[The combined effect of ionizing radiation and smoking on the causation of bronchial carcinoma (author's transl)].

For the prevention of bronchial carcinoma the identification of its causes is of highest priority. Especial attention should be dedicated to the combined action of several factors. In this paper a review is given on the combination effect of simultaneous action of ionizing radiation and smoking observed by epidemiological studies in miners exposed to radon and its consecutive products. The amplifying action of both factors observed under working conditions brought about to refer to such combinations in smokers also outside their working life. This results from the natural loading by radiation of the respiratory tract, from radioactive material in the emmission of power stations on the base of fossil fuels, and from the contents of tobacco with 210Pb and 210Po. The combined action of radiation and smoking is regarded as another motivation to give up smoking strictly.

Air Pollutants, Radioactive