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The structure of visual and kinaesthetic imagery: a free association study.

A free association technique was used to investigate the semantic structure of three forms of encoding: verbal, visual imagery, and kinaesthetic imagery. Kinaesthetic imagery involves imagined bodily identification with the stimuli (animal names) and is included because of its possible involvement in creativity, and in view of the importance of enactive representation in cognitive development. The analysis of evoked associations in terms of the propositional relations they bear to the stimuli, shows that the actor-action-object framework is particularly important in kinaesthetic imagery, and the whole-part structure in visual imagery. Verbal representation gives rise to various abstract and phonemically based association types. The relevance of these findings to creativity and to the concept of semantic memory is discussed.

Association

Free association and changing models of mind.

The method of free association, like most major psychoanalytic concepts, was developed in and has been conceptually tied to a one-person, intrapsychic, drive psychology. Psychoanalysts who have retained the classical, drive-structure metapsychology have continued to emphasize the free association method, while those who have shifted to a relational, two-person, interactional or interpersonal point of view have often minimized or abandoned the free association method. This article explores this unfortunate dichotomy and examines the ways in which the free association method, stripped of its unnecessary tie to drive theory and reconceptualized within the context of a two-person psychology, remains a valuable clinical method. Free association, as a method, can be useful to psychoanalysts of all theoretical orientations as a reminder of Freud's most important discoveries, that is, of unconscious mental life, psychic determinism, psychic continuity, and meaning, as well as of the value and priority of careful, restrained, and disciplined listening to patients and of taking our lead from them. The method of free association, with the corresponding assumption of the analyst's evenly hovering attention, provides a fundamental context within which our personalities and theoretical biases, instead of being disruptions or impositions, become active and analyzable aspects of the analytic process.

Countertransference

Norms for free associations and five types of constrained associations.

Normative data on verbal free associations and constrained associations of five types (opposites, superordinates, examples of categories, coordinates, and properties) were collected from 72 men and 72 women (mean age, 19.2 yr.). A list of the different responses given by subjects for each of 360 stimuli and the frequency of each response is available.

Adolescent

Free association as a method of self-observation in relation to other methodological principles of psychoanalysis.

The method of free association, especially in its self-observative aspect, may be seen as a useful criterion for differentiating among various clinical approaches to psychoanalysis, not only as they evolved in the course of its history but also as they are being practiced today. It is suggested that it may be of some relevance to view the existing variants of clinical psychoanalysis as being based upon differing emphases on one or another of the basic operational concepts, such as free association, interpretation, and the mental disposition of the analyst.

Free Association

Free association and repression-sensitization.

It was predicted that Subjects' scores on Byrne's Repression-Sensitization (R-S) Scale would be related to free associative style. When administered the R-S Scale, Subjects at the high and low extremes then took part in a free association task. Repressers manifested a prevalence of "avoidant" and sensitizers a prevalence of "approach" associations. However, this was true only of male Subjects.

Aggression

The analyst's stance and the method of free association.

The concept of the analyst's stance is employed to organize a number of ideas about psychoanalytic work, past and present, especially from the viewpoint of the method of free association. Beginning with an emphasis on the intrinsic uncertainties and paradoxes of the analytic process, the author reviews the importance of words, the aim of mastering resistances (i.e., promoting freedom of association), and functional neutrality on the analyst's part. The problem of anonymity is considered from a number of angles. Two traditions of transference are described, deriving from Freud's overlapping early formulations. The distinction between old and new determinants in the two kinds of transference is useful and important in the analyst's stance. Attitudes toward insight, resistance, and conflict resolution are considered from the perspective of the distinction between divergent and convergent conflicts, with special emphasis on the role of punitive, unconscious self-criticism.

Free Association

On the dynamic organization of memory. A mathematical model of associative free recall.

The interaction of memory structures and retrieval dynamics is discussed. A mathematical model for associative free recall is presented to support the view that the organization of simple processing units plays an important role in the retrieval of memory traces. Computer simulations show that "flexibility" and "fidelity" of the dynamics strongly depend on the network structure, the amplification and decay parameters, and the noise term.

Association Learning

On the psychophysiology of dreaming: a sensory image--free association hypothesis of the dream process.

A psychophysiological hypothesis of the dream process during REM sleep called "a sensory image-free association hypothesis" is proposed. It is assumed that a state with a sustained EEG pattern of drowsiness (non-REM stage-1) and muscle atonia produces a stream of disorganized and vague thinking as a background mentation during the REM sleep. The phasic excitation of the brain occurring concurrently with the burst of rapid eye movements (REMs) activates the hippocampal-neocortical memory system and draws out sensory images from the memory reservoir of the brain. The dreamer makes a freely organized association about the successive sensory images and makes up a dream story. This hypothesis is compatible not only with the recent neurophysiological findings but also with traditional psychological interpretation of the dream content.

Animals

On the cell-free association of lamins A and C with metaphase chromosomes.

Nuclear envelopes have previously been shown to assemble spontaneously around endogenous chromosomes in cell-free homogenates of mitotic Chinese hamster ovary cells. In order to further analyze the mechanisms underlying nuclear envelope reformation and the functions of the individual nuclear lamin polypeptides, a fractionated cell-free nuclear envelope reassembly system involving purified chromosomes and either a postchromosomal supernatant or a cytosol fraction from mitotic cells has been devised. Results obtained with this fractionated system show that lamins A and C will associate with the surfaces of chromosomes in the absence of lamin B and membranes, this association being inhibitable by ATP-gamma-S. However, in the absence of membranes chromatin decondensation never occurs. Using the reversible swelling of chromosomes in low ionic strength buffers lacking divalent cations as the basis of a simple assay, it is demonstrated that the association of lamins A and C with the surfaces of chromosomes has a pronounced and easily observable effect on chromatin organization.

Animals

Phosphorylation of glucocorticoid receptor-associated and free forms of the approximately 90-kDa heat shock protein before and after receptor activation.

Several lines of evidence have suggested that glucocorticoid receptor function may be regulated by phosphorylation-dephosphorylation reactions, and it has been proposed that dephosphorylation accompanies activation to the DNA-binding form. The phosphate content of the approximately 100-kDa steroid-binding protein has been determined directly and was found not to change during activation in intact cells (Mendel, D.B., Bodwell, J.E., and Munck, A. (1987) J. Biol. Chem. 262, 5644-5648). We have now determined the effect of interaction with the receptor and of activation on the phosphate content of the approximately 90-kDa heat shock protein (Hsp 90), which is thought to be a non-steroid-binding subunit of nonactivated glucocorticoid receptors that dissociates on activation. Monoclonal antibodies AC88 and BuGR2 were used to purify free Hsp 90 and cytosolic nonactivated glucocorticoid-receptor complexes, respectively, from WEHI-7 cells grown in the presence of 32Pi and [35S] methionine. Cell-free activation of the nonactivated receptor-antibody complexes immobilized on protein A-Sepharose minicolumns allowed the recovery of the Hsp 90 dissociated from the complexes during activation. Proteins were separated by denaturing polyacrylamide gel electrophoresis, and the 32P/35S ratio, which was used as a measure of the phosphate content relative to protein, was determined for the free, receptor-associated, and dissociated forms of the Hsp 90, as well as for the approximately 100-kDa steroid-binding protein of non-activated and activated receptors. The three forms of the Hsp 90 had the same phosphate contents, as did the approximately 100-kDa steroid-binding protein before and after activation. Based upon these results, we conclude that no net change in the phosphorylation occurs when the Hsp 90 associates with the approximately 100-kDa steroid-binding protein to form nonactivated receptors and that neither protein component of nonactivated complexes is dephosphorylated when they dissociate during thermal activation under cell-free conditions.

Animals

Acquired von Willebrand disease associated with free lambda light chain monoclonal gammopathy, normal bleeding time and response to prednisone.

We report a case of acquired von Willebrand's syndrome with severe gastrointestinal bleeding and associated free monoclonal lambda light chains. The patient had a rapid sustained clinical and laboratory response to the administration of prednisone. Of note in this patient was the occurrence of angiodysplasia which has previously been reported in association with acquired von Willebrand's syndrome. No inhibitors of VWF:Ag, VWF:RCoF, or factor VIII:C were detected by mixing studies and the bleeding time was normal. Very few high molecular weight von Willebrand multimers were present prior to prednisone; however, the pattern reverted to a normal distribution following treatment. In appropriate patients with acquired von Willebrand's syndrome and monoclonal para-proteins, a trial of prednisone may be indicated.

Bleeding Time