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Results for “Gingival Neoplasms”

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At least 19 recordsLinked to original sources
PubMed1986

Hemangioendothelioma of the gingiva. Histopathologic and therapeutic considerations.

The hemangioendothelioma is a benign neoplasm, rarely observed in the mouth. In the literature, reports on the treatment and on the therapeutic results are lacking. This type of gingival neoplasm was observed in a young adult male. It was located in the attached gingiva in the upper and in the lower jaw, covering almost the entire coronal part of the anterior teeth. An exhaustive internal and neurological examination revealed no associated general disease. The gingival biopsies displayed the typical characteristics of a hemangioendothelioma: proliferation of the blood vessels, with a reduced lumen surrounded by swollen endothelial cells. The treatment consisted of a meticulous mechanical plaque control, chlorhexidine rinses, gingivectomy procedures and a monthly professional prophylaxis. 3 years after the periodontal treatment, the gingival structures remained clinically healthy. In the biopsies, only a small amount of inflammatory cells could be detected. This report shows a case of benign gingival neoplasms of unknown etiology in which meticulous plaque control, combined with extensive gingivectomies and repeated professional prophylaxis may have prevented or, at least, retarded the recurrence of the lesion.

Adolescent↗
PubMed1994

Peripheral odontogenic fibroma.

The peripheral odontogenic fibroma is characterized by a fibrous or fibromyxomatous proliferation that contains varying amounts of odontogenic or presumed odontogenic epithelium. It has been considered a rare gingival neoplasm that, because of a lack of follow-up information in most reported cases, has had an unknown biologic behavior. Clinical data from this study indicate that the lesion is more common than previously reported and that it has a significant recurrence rate. Light and electron microscopic data reveal a relatively broad spectrum of epithelial and mesenchymal components, including a rare granular cell type. Because the presence of both epithelial and mesenchymal elements are required for its diagnosis, the lesion is logically classified as a mixed epithelial/mesenchymal odontogenic tumor, rather than a purely mesenchymal tumor.

Adolescent↗
PubMed1992

Bronchogenic metastasis to the gingiva.

We report a rare case of a bronchogenic adenocarcinoma metastatic to the lower gingiva as the first clinical sign of metastatic disease. The following safe approach is recommended: a tumor in the oral cavity should be regarded as malignant or as a metastasis until the hypothesis can be abandoned.

Adenocarcinoma↗
PubMed1992

Gingival lesions of HIV infection in 178 Greek patients.

One hundred seventy-eight HIV-infected Greek patients were examined and the gingival lesions were recorded. At the time of oral examination, 77 patients were HIV positive, 53 had ARC, and 48 had AIDS. The mean age of the patients was 36.6 years; 158 were men and 20 were women. Fifteen different gingival lesions were recorded. Necrotizing gingivitis (10.1%), gingivitis (5.0%), periodontitis (18.5%), candidiasis (5.8%), and Kaposi's sarcoma (5.0%) were the most common lesions observed. Oral lymphomas and other lesions were recorded in low numbers. Our findings show that dentists should be aware of gingival lesions of HIV disease because some of them are common and diagnostically important.

AIDS-Related Complex↗
PubMed2006

Unusual presentation of primary squamous cell carcinoma involving the interdental papilla in a young woman.

A 33-year-old woman presented with what looked like an epulis at the interdental papilla between 22 and 23. We excised the lesion and histopathological examination surprisingly showed the presence of a well-differentiated squamous cell carcinoma that was not invading the underlying bone. We then did a radical excision including extraction of teeth followed by bony reconstruction. No recurrence or metastases have been seen during a follow-up of 12 months.

Adult↗
PubMed1990

Oral manifestations of non-Hodgkin's lymphoma in HIV-infected patients.

The incidence of non-Hodgkin's lymphomas (NHL) in patients infected with human immunodeficiency virus (HIV) is relatively high. However, there have been few reports on the clinical and histopathological features of oral manifestations of NHL in these patients. The lesions reported so far were all tumorous swellings with or without ulceration, as in non-HIV-infected patients. In this report 3 cases are presented of HIV-infected patients with solitary, primary oral NHL. These lesions showed a striking resemblance to acute, necrotizing gingivitis, a common finding in these patients, thus making the diagnosis more difficult.

Acquired Immunodeficiency Syndrome↗
PubMed1997

Basaloid squamous cell carcinoma of the esophagus metastatic to the gingiva: a case report.

Basaloid squamous cell carcinoma (BSCC), a biologically high-grade variant of squamous cell carcinoma, carries a grave prognosis. In this article, we describe a rare case of BSCC of the esophagus with metastasis to the mandibular gingiva in a 63-year-old man. In addition, we provide a review of the relevant literature along with a discussion of the differential diagnosis.

Carcinoma, Basosquamous↗
PubMed1996

AIDS-related non-Hodgkin's lymphoma presenting as delayed healing of an extraction wound.

Non-Hodgkin's lymphoma (NHL) of the oral cavity frequently occurs in patients infected with human immunodeficiency virus (HIV). This report describes a lesion presenting as delayed healing of an extraction wound with hyperaemic swollen gingivae and ulceration in an apparently healthy 34-year-old Thai fisherman. The lesion was the first evidence of his HIV-positivity. It is, therefore, imperative that clinicians should consider a diagnosis of HIV infection in cases of non-healing extraction wounds in patients in high risk categories.

Adult↗
PubMed1999

Autocrine and paracrine motility factors and their involvement in invasiveness in a human oral carcinoma cell line.

Invasive potentials of malignant cancer cells are regulated by cell motility factors. To examine the regulation of motility and invasiveness in oral squamous carcinoma, we investigated autocrine- and/or paracrine-acting cell motility factors, using a newly established human cell line (IF cells) from oral squamous cell carcinoma, which has highly invasive and metastatic characteristics. Conditioned medium derived from IF cells stimulated cell scattering and migration of GB-d1 gallbladder carcinoma cells, indicating that IF cells secreted cell motility factors. Using antibodies, IF-derived cell motility factors proved to be transforming growth factor (TGF)-alpha and TGF-beta1. Antibodies against TGF-alpha and TGF-beta1 inhibited autonomous migration of the IF cells. On the other hand, in vitro invasion of IF cells was strongly enhanced by hepatocyte growth factor (HGF) but only slightly by TGF-alpha and TGF-beta1. The conditioned medium from fibroblasts enhanced in vitro invasion of IF cells, an event abrogated by anti-HGF antibody, but not by antibodies against TGF-alpha and TGF-beta1. Importantly, IF cells secreted a factor inducing HGF production in fibroblasts and the factor was identified as interleukin-1, which means that a mutual interaction exists between tumour cells and fibroblasts, as mediated by the HGF/HGF-inducer loop. These results indicate that IF cells utilize TGF-alpha and TGF-beta1 as autocrine-acting motility factors and HGF as a paracrine-acting motility factor, and that invasiveness of IF cells is particularly stimulated by HGF derived from stromal fibroblasts. Utilization of multiple cell motility/invasion factors that act in distinct pathways may confer highly invasive and metastatic potentials in IF oral squamous carcinoma cells.

Carcinoma, Squamous Cell↗
PubMed1993

T-cell lymphoma associated with periodontal disease and HIV infection. A case report.

A case is described of gingival non-Hodgkins lymphoma presenting in a site previously diagnosed as HIV-periodontitis. The lymphoma presented along with other signs of HIV infection and AIDS, which taken together were compatible with increased immunosuppression and reactivation of Epstein-Barr virus. The implications of these findings are discussed, and it is suggested that areas of gingiva which show rapid localised recession, associated with HIV seropositivity, should be monitored closely and considered for biopsy if abnormal signs are detected.

Acquired Immunodeficiency Syndrome↗