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At least 19 recordsLinked to original sources
PubMed1975

Incubation as a form of psychotherapy in the care of patients in ancient and modern Greece.

Incubation or temple sleep in sanctuaries of Aesculapius, Amphiaraos, Trophonios, etc., for the care of patients was practised even in the older times of ancient Greece and may be viewed as a form of psychotherapy and especially as 'dream-psychotherapy'. In Greek antiquity, as it is known, dreams were considered as a way of communication between gods and men. Survival of the custom of incubation exists even in our times in modern Greece, but are disappearing slowly. An attempt is made to find an explanation, if any, of those miraculous cures in accordance with the scientific thought of today.

Dreams↗
PubMed1976

Seroepidemiological study of HBV infections in Athens, Greece.

A seroepidemiological survey of a sample-roughly representative by age and sex - of 2744 persons of the Greater Athens area revealed that hepatitis B virus (HBV) infections are highly endemic in Greece. Hepatitis B surface antigen (HBsAg) was detected in 72(2-6%) of them. The subtype was identified in 70 of the 72 carriers, and 69 were ay; the other was ad. Determinant w was present in all 61 that were capable of being typed further, and a23y(w) was twice as common as a11y(w). Antibody to HBsAg (anti-HBs) was found in 514 (18-7%) persons. The prevalence of the HBsAg rose rapidly with age, reaching peak values (5-3%) at 20-29 years, while anti-HBs reached its highest value (42-1%) in older age groups (50-59 years). The frequency of HBsAg was significantly higher in males (3-4%) than in females (1-5%). The percentage of infected persons who become chronic HBsAg carriers (12-3%) was found higher than in other developed populations. It was also found higher in children (25%) than in adults (5-5%) and in males (14-6%) than in females (8-1%). These data indicate that HBV infection in early life is a major risk factor in the development of HBsAg carriers and support the hypothesis that males are more likely to become HBsAg carriers than females.

Adolescent↗
PubMed1977

Visceral leishmaniasis acquired in Greece: diagnosis and treatment in an American child.

Reported is a case of visceral leishmaniasis acquired in Greece by a 3-year-old American child. Untreated, this protozoan infection causes a high mortality. Specific treatment is available, making early recognition of the illness important. This child's infection responded dramatically to a course of sodium antimony gluconate. Repeat bone marrow cultures demonstrated persistent organisms and a second course of treatment was required. Monitoring of his response to therapy suggested that serial bone marrow cultures and the neutrophil response may be sensitive means for following the course of this infection.

Antimony Sodium Gluconate↗
PubMed1978

A laboratory evaluation of fluoride dentifrices used in Greece.

A laboratory investigation of the fluoride dentifrices commonly used in Greece was done in order to evaluate their caries-preventive potential. The evaluation was based on the determination of the free ionic fluoride and the total soluble fluoride present by a potentiometric fluoride electrode technique. Dentifrices containing MFP, NaF and AlF3 were analyzed. The measured total soluble and free ionic fluoride content were discussed in conjunction with the various dentifrice components. Most of the examined dentifrices were MFP type and the free ionic fluoride was found to vary from 130 to 180 parts/10(6) F-.

Dentifrices↗
PubMed1977

Effect of insecticide spraying for malaria control on the incidence of sandfly fever in Athens, Greece.

Sera from 637 Athens residents of various age groups were examined by plaque reduction neutralization test for antibodies against Naples and Sicilian Phlebotomus fever viruses. A marked change in the prevalence of antibodies to both agents was observed in persons born after 1946, when residual insecticide spraying for malaria control was initiated in Greece. The prevalence of Naples and Sicilian neutralizing antibodies among residents greater than or equal to 30 years of age was 36% and 13%, respectively. In contrast, only 4% of persons less than or equal to 29 years of age had Naples antibodies and all were negative to Sicilian. These serologic data confirm previous clinical observations that sandfly fever becam uncommon in Athens after initiation of the insecticide spraying program. Presumedly the spraying program was effective in reducing the Phlebotomus population to levels where virus transmission was minimal. New information on the specificity and duration of Phlebotomus fever neutralizing antibodies is also presented.

Adolescent↗
PubMed1977

[Pityriasis versicolor in Greece and its predisposition factors].

The age and seasonal incidence of 2610 patients with pityriasis versicolor in Greece were studied. Determination of the pH of Na and K ions of the sweat and the microbiol flora of the skin of pityriasis versicolor patients was undertaken. Besides these the effectiveness of a 1% selenium disulfid suspension was tested. The results indicate that the age groups of 20-29 and 30-30 years are mostly affected by the disease. A high incidence of the skin manifestation was noted during the summer and fall months. A difference of the pH of the sweat between pityriasis versicolor and healthy controls was observed, but no difference was found in the Na and K ions of the sweat among these two groups. Neither did the microbial flora from the skin lesions of patients and from corresponding sites of controls show any difference. The high relapse in this experiment indicates the relative ineffectiveness of selenium disulfid preparations when used as a 1% suspension in the treatment of pityriasis versicolor.

Adolescent↗
PubMed1979

Serological evidence of human leptospirosis in northern Greece.

a) 1069 human blood samples were tested for the presence of C. F. antibodies to leptospirae. 98 of these sera were from patients suffering from Weil's syndrome. 13 out of 98 patients were found to be suffering from leptospirosis; one of these died. 460 sera were from patients with febrile (acute) illness of unknown origin and 511 sera from patients with respiratory disease (especially "influenza like disease"). None of these patients was found to be suffering from leptospirosis. b) 191 human sera from healthy people at risk to leptospiral infection were examined by microscopic agglutination test (MAT). A high percentage (14.1%) was found to have antibodies against one or two leptospiral serogroups. The results obtained suggest that the incidence of leptospiral infections in humans in Northern Greece is higher than previously reported and the predominant serogroups were found to be Icterohaemorrhagiae followed by Autumnalis and Canicola.

Agglutination Tests↗
PubMedDate not supplied

[Epidemiology of acute leukemia of childhood in Greece (author's transl)].

A retrospective study of 151 aged less than 15 years children suffering from acute leukaemia is reported, the parameters studied were male: female ratio, type of leukemia, age and seasonal distribution of the illness. The disease started in spring in 53 children (35,1%), in summer in 34 (22,6%), in autumn in 36 (23,8%) and in winter in 28 (18,5%). The difference between spring and winter was statistically highly significant (X2 = 10,54, P less than 0,005). Sixty two children (41%) were 3-5 years old. The male female ratio was 1.75. The disease was of the acute lymphoblastic type in 88,1% of the cases.

Adolescent↗
PubMed1979

[2 new esterase loci Es-14 and Es-15 in mice (genus Muc L.) : characterization by different substrates and inhibitors].

Allelic differences at an esterase locus designated Es-14 exist between Mus musculus (both inbred strains and wild Mice) and Mus spretus. This locus is expressed in a variety of tissues. Mus musculus has been assigned the allele Es-14r while Mus spretus carries the alternate alleles Es-14l. Each phenotype manifests itself as a single band of enzyme activity and F1 hybrids show two bands corresponding to the parental forms. Allozyme variation was also detected at another esterase locus, temporarily disignated as Es-15 until confirmed by current linkage analysis. A slow variant Es-15 was recorded in a Mus musculus population from Greece while inbred strains carry the Es-15m allele. Study of a Mus spicilegus population from Greece revealed the presence of a third allele, Es-15r. Substrate and inhibition characteristics are provided for both loci.

Alleles↗
PubMed2026

Comprehensive molecular profiling of advanced NSCLC in Greek patients:A prospective HeCOG study.

BACKGROUND: We report for the first time the molecular landscape and outcome associations from the prospective CLIMEDIN trial in Greece. METHODS: Two hundred patients with newly diagnosed advanced NSCLC (March 2022-October 2023) were enrolled and randomized to standard-of-care education versus additional automated, adverse-event-targeted digital interventions. Within this study baseline testing (EGFR, ALK, PD-L1) was performed in all; 165 tumors underwent comprehensive NGS (Oncomine Comprehensive Assay v3). Primary endpoint was improvement in AEs/QoL; secondary endpoints included ORR, PFS and OS. Associations between genomic alterations and outcomes were explored. RESULTS: Median age was 68 years; 75% male; 52% current smokers; adenocarcinoma 68.5%. Most received chemo-immunotherapy (66%). At data cut-off (December 2025; reverse-Kaplan-Meier median follow-up 36.3 months), median PFS was 9.6 months and median OS was 15.2 months. Across 200 tumors, 495 pathogenic variants (PVs) were identified in 83 genes. Exploratory outcome analyses showed longer OS in EGFR-mutant disease (preserved under parsimonious multivariable adjustment) and a formal KRAS × smoking interaction for OS (interaction P = 0.011). CONCLUSIONS: In this cohort, the molecular profile mirrors other Caucasian series, with clinically relevant enrichment patterns for EGFR and KRAS. ECOG performance status and first line treatment were the dominant prognostic factors in this cohort. A novel KRAS and smoking interaction for overall survival warrants prospective validation.

Aged↗
PubMed1978

A longitudinal study of oral health in immigrant children in Sweden.

Children immigrating into Sweden from Finland and Southern Europe (Greece, Yugoslavia and Turkey) were subjected to a longitudinal study on caries activity and gingival condition. For each immigrant child a Swedish "twin" of the same sex and age was used as a control. Out of 124 pairs originally examined, 75 were reexamined after a 2 1/2-year stay in Sweden. The study showed that on arrival in Sweden the Finnish children had more caries and a higher Gingival Index (GI) than the controls and that they acquired more carious lesions during their stay in this country. Their GI, however, did not develop less favorably than that of the Swedish controls. The South-European children did not seem to have more carious lesions than the Swedish controls on arriving, nor did they seem to acquire more carious lesions during the period of observation. Their GI was higher at the first examination but the change in this index ran parallel with that of the controls. It was concluded that the children immigrating from Finland should be considered a risk group with regard to oral health.

Adolescent↗
PubMed1975

The relation of infection with the hepatitis B agent to primary hepatic carcinoma.

In Asia, Africa, and other tropical areas, primary hepatic carcinoma (PHC) is associated with liver cirrhosis of the postnecrotic (macronodular) type. Chronic viral hepatitis is likely to be the cause of this cirrhosis in many patients from regions where chronic infection with the hepatitis B virus (HBV) is common. More than 95% of patients with hepatoma (in Mali and Senegal) have evidence of infection with HBV, a much higher frequency than in controls. Thirty-nine of 62 patients with PHC had hepatitis B surface antigen (HBsAg) (controls, 8 of 98) and 56 of 63 (controls, 26 of 100) had antibody against hepatitis B core antigen (anti-HBc). In earlier studies, we demonstrated a maternal effect of HBsAg. If the mother has the antigen and the father does not, the children are much more likely to also have HBsAg than if the father has the antigen and the mother does not (93/161 = 57.8% when mother is positive vs. 28/135 = 20.7% when father is positive; P = 0.6 X 10(-10)). Studies in Greece and in the Solomon Islands show that presence of HBsAg in parents affects the sex ratio of the offspring of the mating. This implies that the presence of the agent in a parent can affect the fetus early in life. Parental studies in the west African hepatoma patients showed that there is a very high frequency of HBsAg in mothers (71.6%), while the frequency in fathers (18.5%) is significantly less. This suggests that the development of hepatoma in offspring is related to infection in parents. Several years ago, we described a vaccine which may be useful in preventing infection with hepatitis B. Strategies are discussed which might be effective in preventing the development of carriers with, it is hoped, a consequent decrease in the frequency of HBV carriers, chronic hepatitis, and primary hepatic carcinoma. The strategy would employ methods for decreasing the frequency of the agent in the environment by the application of public health methods including the vaccination of appropriate newborns and other members of the population.

Africa↗