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Epidemiologic studies of coronary heart disease and stroke in Japanese men living in Japan, Hawaii and California. Coronary heart disease risk factors in Japan and Hawaii.

Various risk factors were evaluated to explain a significantly greater incidence of coronary heart disease in men of Japanese ancestry resident in Hawaii compared with men resident in Japan. The independent predictors of incidence of coronary heart disease in both Japan and Hawaii were systolic blood pressure, serum cholesterol, relative weight and age. These factors appeared to influence incidence similarly in both areas because in each case the correlation coefficients for Japan and Hawaii did not differ significantly. The hypothesis that the greater incidence in Hawaii could be attributed to differences in levels of these risk factors was tested with the Walker-Duncan method. The four variable multiple logistic function describing the probability of coronary heart disease in Japan was applied to the cohort characteristics observed in Hawaii. The estimated incidence thus obtained was not significantly different from that actually observed in the men resident in Hawaii. Therefore the increased coronary risk profile in Hawaii compared with Japan can account for the greater incidence of coronary heart disease in the former. Current cigarette smoking was significantly related to the risk of coronary heart disease in Hawaii but not in Japan. This difference requires further investigation.

Age Factors↗

Epidemiologic studies of coronary heart disease and stroke in Japanese men living in Japan, Hawaii and California: incidence of stroke in Japan and Hawaii.

As part of the Ni-Hon-San Study, stroke incidence was compared in the Japan and Hawaii cohorts. Stroke cases were classified in two types, intracranial hemorrhage (ICH) and thrombo-embolic stroke (T-E). For each type the incidence in Japan was about three times as great as in Hawaii. The ratio ICH/T-E was 1/2.2 and 1/1.6 in Japan and Hawaii, respectively. Blood pressure was the most important risk factor, followed by age for total stroke in both Japan and Hawaii. Proteinuria was also a risk factor in Hawaii. Conversely, an index of animal food intake was inversely related to total stroke, significantly in Hawaii, and at a suggestive level for total and hemorrhagic stroke in Japan. Since the levels of blood pressure do not differ between Japan and Hawaii, one possible explanation for the large difference in stroke incidence between the two cohorts may be the fact that animal protein and saturated fat intake, which is inversely associated with stroke incidence, is much greater in Hawaii than in Japan. This explanation would support epidemiologic and experimental studies in Japan which suggest that dietary animal protein and fat exert an inhibitory effect on the incidence of stroke.

Age Factors↗

Healthy people in Hawaii?: an overview of ethnic health disparities in Hawaii for the Healthy People 2010 initiative targeted health concerns.

Significant health disparities exist between ethnic groups in the United States. The authors reviewed literature examining the epidemiology of health disparities in Hawaii's multiethnic population. One of the primary goals of the Healthy People 2010 initiative is to eliminate health disparities, specifically cancer, cardiovascular disease, diabetes, infant mortality, child and adult immunizations and HIV/AIDS. However, the research on ethnic health disparities is fragmented, especially in Asian/Pacific Islanders. Unclear definitions of ethnicity (i.e., self-report, mixed ethnicity, etc) and aggregated study populations (i.e., combining multiple ethnic groups into one category) obscure the true health status of ethnic minorities in Hawaii. This paper presents an overview of the state of the literature on Hawaii ethnic health disparities.

Acquired Immunodeficiency Syndrome↗

Operation storefront Hawaii: tobacco advertising and promotion in Hawaii stores.

Our objective was to explore the nature and location of tobacco product advertising and promotion in retail stores in Hawaii. We performed a cross-sectional study of tobacco product store-based advertisements, including the number, location (indoor/outdoor; proximity to candy, toys, school), size, and brand of the ads. Trained youth (ages 12-19 years) collected data on 3,151 advertisements and promotions among 184 stores. We found that most ads appeared indoors, and the most heavily advertised brand was Kool. Kool is also the most heavily smoked brand among youth in Hawaii. This study underscores the high visibility of retail store advertising and promotions (both indoor and outdoor) in places that attract the attention of youth.

Advertising↗

Hawaii's Neuromuscular Disease Biopsy Registry. A quarter-century compilation of muscle biopsy diagnoses in Hawaii.

INTRODUCTION: The Department of Pathology at Straub Clinic & Hospital began using enzyme histochemical techniques to examine muscle biopsies in 1976 and has processed most of the muscle biopsies performed in Hawaii for the past 25 years. A Muscle Biopsy Registry of biopsy findings was established in 1992 and information concerning 1,230 biopsies during the period December 1976 to June, 2000 entered into the Registry's data base. The goal was to document data derived from biopsy-based diagnoses of neuromuscular diseases since none currently exists. METHODS: Muscle biopsies received in a fresh state in the Straub Pathology Department were processed utilizing a modern approach incorporating routine histological and enzyme histochemical staining techniques of frozen sections. One pathologist [LJL] documented findings and established diagnoses for all cases. Patient information, demographics and diagnoses were recorded utilizing a Microsoft Excel spreadsheet program. RESULTS: Data sorts conducted from the Registry's data base of 1,230 biopsies produced graphs and tables illustrating demographic statistics regarding diagnoses and findings in 1,044 different patients some of whom had multiple biopsies. CONCLUSIONS: Hawaii's Neuromuscular Disease Biopsy Registry constitutes a compilation of a quarter-century of muscle biopsy-based diagnoses utilizing enzyme histochemical diagnostic techniques in pediatric and adult age groups, including specific diagnoses encountered in different ethnic groups. This information constitutes a benchmark for future epidemiologic studies, and a basis for comparison with data derived from clinical diagnoses and data derived from Death Certificates.

Biopsy↗

Arthropod succession on exposed carrion in three contrasting tropical habitats on Hawaii Island, Hawaii.

Decomposition studies were conducted using domestic pig carcasses to determine arthropod succession patterns on exposed carrion for the island of Hawaii. The carcasses were placed in upland forest and woodland (1,877 m), rainforest (1,169 m) and midelevation woodlands (646 m) habitats. Marked differences in species composition, rates of biomass removal, and succession patterns were observed between these 3 sites. These results also differed from patterns observed during previous decomposition studies conducted on the island of Oahu.

Animals↗

A descriptive epidemiologic study of HIV-infected individuals in Hawaii: report of the Hawaii Sero-Positivity and Medical Management database (HSPAMM).

This is a retrospective study of the HSPAMM database evaluating differences in clinical, laboratory, HIV-risk factors and demographic characteristics with respect to gender and ethnicity. There were no significant differences comparing gender, and Hawaiians and non-Hawaiians with respect to developing a CD4 count < 200 cells/mm3. HSPAMM contains information on a large number of HIV-infected Asians/Pacific Islanders.

Adolescent↗