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Results for “HERPES ZOSTER, OCULAR”

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At least 19 recordsLinked to original sources
PubMed1985

Herpes zoster ocular infection.

A retrospective analysis of 171 patients with herpes zoster ocular infection has been carried out to determine the effect of treatment with either topical acyclovir, topical steroids, or a combination of both. Acyclovir was superior to steroids and to the combination. Treatment with topical acyclovir was on average 54 days compared with 200 days with steroids, and recurrences were 6% with acyclovir compared with 50% with steroids.

Acyclovir↗
PubMed1983

A review of acyclovir treatment of ocular herpes zoster and skin infections.

Intravenous acyclovir had a significant effect on the resolution of the skin rash in patients with acute zoster, but the 5-day course of therapy was not, in itself, sufficient to treat coexisting ocular involvement. In an open study, topical acyclovir was found to control herpes zoster kerato-uveitis, without recurrences and in a shorter time than if steroids alone were used. The use of steroids in combination with acyclovir led to prolonged treatment and high recurrence rates. A comparative trial of topical acyclovir versus steroids in the treatment of acute herpes zoster kerato-uveitis showed significant differences in favour of acyclovir in terms of the time to resolution of corneal epithelial disease, total treatment duration and the numbers of patients having a recurrence of infection. The reductions in treatment duration and recurrence rate would be expected to result in a reduced incidence of ocular damage and visual loss in acyclovir treated patients.

Acyclovir↗
PubMed1981

Topical acyclovir in herpes zoster ocular involvement.

Topical acyclovir has been found in 15 out of 18 patients to control, without recurrences and in an appreciably shorter time than if steroids were used, keratoconjunctivitis induced by herpes zoster. Once steroids were started, recurrences occurred during withdrawal of steroids or after they had been stopped.

Acyclovir↗
PubMed1991

Double-masked trial of topical acyclovir and steroids in the treatment of herpes zoster ocular inflammation.

Ninety seven new patients with ophthalmic zoster were randomly allocated to three topical treatment groups: acyclovir (ACV) ointment and placebo drops (AP), placebo ointment with steroid drops (PS), and acyclovir ointment with steroid drops (AS). The dosage administered was determined by the score of the ocular inflammation. Follow-up was for at least one year. The results showed that topical ACV alone is insufficient for severe ocular inflammation but is not inclined to lead to recurrences in milder cases. Topical steroid alone is effective but tends to necessitate prolonged treatment. Combined steroid and ACV is questionably better than steroid alone and causes marginally fewer rebound inflammations.

Acyclovir↗
PubMed1984

[Ocular herpes zoster and delayed cerebrovascular accident: report of a case].

A sixty-nine year old man suffered a stroke fourteen weeks after the onset of right herpes zoster ophthalmicus (HZO). Hemispheric infarction was documented by a computed tomography which showed a small hypodense zone in the right internal capsula; after contrast there was enhancement of this hypodense area. Cerebral angiography and cerebral-spinal fluid were not done. Despite of a diagnosis of probability the authors report the case and review the literature. A long latency between the HZO and onset of neurological deficit is stressed. New antiviral agents may prevent the ictus.

Aged↗
PubMed1988

[Ocular herpes zoster with contralateral hemiplegia].

A total of 375 patients with neurologic syndromes of herpes zoster were studied. Ten of them presented, along with the involvement of the first branch of the trigeminal nerve and other cranial nerves, contralateral pyramidal symptomatology. Apart from the typical syndrome of herpes zoster ophthalmicus with contralateral hemiplegia the authors distinguished clinical variants in which contralateral pyramidal symptomatology was associated with acute meningoencephalitis.

Adolescent↗