[Study on the indoor climate and habitation-hygiene in the high humid zone. I. On the measurement of the indoor temperature and relative humidity in high humid zone].
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Water intake, food intake (wet and dry weight), rectal temperature, and food digestibility were determined in 6 sheep exposed to 4 weeks each of hot-humid, hot-dry, and cool-humid environments, alternated with 3 weeks each of cool-dry exposure. Compared with values determined during the cool-dry environments, wet-weight food intake decreased between 5% and 33% and between 3% and 9% during hot-humid and hot-dry exposures, respectively. During the week of cool-humid exposure, wet-weight food intake decreased by 11%. During hot-humid, hot-dry, and cool-humid environments, dry-weight food intake decreased between 5% and 17%. The effect of high ambient temperatures on wet-weight food intake was significant (P less than 0.01), whereas dry-weight food intake was not related to ambient temperature. During hot-humid exposure, water intake decreased 4% and the increased 7%. During hot-dry exposure, water intake increased between 37% and 45%. During the first 2 weeks of cool-humid environment, water intake decreased between 13% and 15%. From the 4th week of hot-humid exposure until the 3rd week of the following cool-dry period, food digestibility increased between 18% and 32%. During hot-dry exposure, food digestibility increased between 6% and 14%. The digestibility of food was significantly increased (P less than 0.005) when dry-weight food intake increased; therefore, decreased digestibility was related to water content of the feed. Increased ambient humidity was associated with decreased dry-weight food intake (P less than 0.05).
Humidification of inspiratory gases under anaesthetic conditions still is a matter of controversial discussion. Physiological humidification and heating of breathing air are preconditions for mucociliary clearance, pulmonary cleaning and defence mechanisms. These functions of the upper respiratory tract are eliminated by application of artificial airways. In general the humidification of inspiratory gases should not remain under 70% of relative air humidity at 37 degrees C. Under clinical conditions it is problematic to ensure sufficiently rapid and reproducible measurements of humidity during breathing cycles. We developed a measuring method that enables to make these measurements without big mechanical device. Aim of this investigation was to measure air humidity in typical semiclosed systems during anaesthesia and semiopen CPAP-respiration. The necessity and efficiency of a heat and moisture exchanger (HME) was to be investigated as well. After approximately 5 minutes there was an inspiratory relative air humidity not below 70% at 28 degrees C (19 mg H2O/l humid air) within the breathing circuit with CO2 double-absorber. By using an HME it is possible to increase relative air humidity within this system to 86% at 29.5 degrees C (25 mg/l). After one hour's respiration with this system without HME a relative humidity of 87% at 30 degrees C (26 mg/l) is reached after replaced HME. Initial relative humidity in a semiopen CPAP-system is about 12% at 28 degrees C (3 mg/l). This is increased to 85% at 29.5 degrees C (25 mg/l) after 15 minutes respiration with HME.(ABSTRACT TRUNCATED AT 250 WORDS)
The influence of the heat-und humidity-exchanger Humid-Vent-Mini on CO2-washout was examined in an neonate lung model varying leakage, pressure and flow. We compared the performance of Humid-Vent-Mini to an exchanger modified and simplified by us in which the filter has been attached directly to the connector of the tracheal tube and to a system without any exchanger. In order to examine the influence of dryness and humidity we examined the exchanger in both states. Under all conditions the heat- and humidity exchanger Humid-Vent-Mini exhibited a significant CO2-retention (p less than 0.01). The modified type also showed a CO2-retention which was markedly lower compared to Humid-Vent-Mini (p less than 0.01). The CO2-washout effect (when measured under conditions of small leakage, reduced pressure and flow) was slightly better in a moist state of the filter compared to complete dryness (p less than 0.01). These results show, that the use of heat- and humidity-exchanger is not advisable.
It has been previously demonstrated that under certain environmental conditions, expired air is not fully water saturated because of the low relative humidity of the first part of the expirate. This finding is of interest to those involved in respirator research, particularly those who design and test robotic metabolic simulators. These simulators must accurately mimic the physiological responses of human airways to breathing air of various temperatures and relative humidities (RHs). Because these responses are not fully quantified, this study examined the mean relative humidity of expired air during four inspired air conditions: cool dry (26 degrees C, 60% RH), cool humid (26 degrees C, 95% RH), hot dry (45 degrees C, 11% RH), and hot humid (45 degrees C, 95% RH). These conditions were administered during three exercise intensities: rest, low (35% VO2max), and moderate (70% VO2max). As compared to the cool dry (CD) condition, frequency of breathing (f) was 9.3% lower and tidal volume (VT) was 9.4% greater across all exercise intensities for the hot humid (HH) condition (p less than 0.05). Mean expired relative humidity (ERH) was substantially lower for the hot dry (HD) condition as compared to the other three conditions during each sampling period. These findings support the conclusion that the mean ERH of expired air depends upon several respiratory and environmental factors in addition to inspired air temperature.
OBJECTIVES: Since the introduction of a humidifier with a heating wire, we have frequently experienced severe upper airway obstruction from consolidation of secretions, previously unencountered when a humidifier without a heating wire was used. Such problems led to the suspicion that the heating wire incorporated into the breathing circuit of the heated humidifier might be the cause. Therefore, we scheduled an experiment to assess the hypothesis that relative humidity, rather than absolute humidity, is a dominant factor in the case of drying secretions in the upper airway when using such a humidifier. DESIGN: Three clinical case reports and an experiment with a tracheal model. SETTING: Intensive care units at Saitama Medical Center, Saitama Medical School, Saitama, Japan. PATIENTS: Three intubated patients. MEASUREMENTS AND MAIN RESULTS: An experiment with a tracheal model showed that gas with a higher temperature and lower relative humidity (35 degrees C, 48%) deprived the tracheal model of significantly more water (5.9 +/- 0.2 [SD] g) than gas with a lower temperature and higher relative humidity (24 degrees C, 87%) (2.9 +/- 0.4 g; p less than .01), even though the gases contained the same amount of water vapor (19 mg H2O/L) minus the same absolute humidity. CONCLUSIONS: A heated humidifier with a heating wire incorporated into the breathing circuit may be dangerous when only temperature is monitored and controlled. Relative humidity, rather than absolute humidity, is a dominant factor in the case of drying secretions in the upper airway when using such a humidifier.
The Vaisala Humicap humidity meter was used to estimate the moisture of the skin. The one-minute relative evaporation (OMRE) was regarded as a manifestation of the skin humidity and assessed in areas with and without sensation. When the sweat glands were inactive, the humidity on the whole was the same in both areas. After they were activated by sun exposure, there was a great rise in humidity in the sweating areas, but the nonsweating areas also had a marked increase. However, after 20 minutes' rest indoors, the patients' humidity returned from the increased level to the level before sun exposure. Soaking the feet, followed by Vaseline rubbing, did not give more hydration than Vaseline rubbing alone. Thus foot soaks have no rational basis for restoring dry skin to normal. Application of ordinary zinc oxide adhesive tape, on the other hand, proved to be a very effective way to hydrate the skin, but for practical use only in limited areas. The urgent need of an "extra skin" for the soles and margins of the soles was stressed for two vital reasons: to prevent dryness and to provide protection.
The decadeoxynucleotide d(AAAAATTTTT)2 in duplex form and the double-helical polynucleotide poly(dA).poly(dT) have been studied by Raman and infrared (IR) spectroscopy under a variety of environmental conditions. The IR spectra have been taken of cast films and compared to the IR spectra of the alternating poly(dA-dT), which shows clear B-genus and A-genus vibrational spectra under conditions of high (greater than 92%) and low (75%) relative humidity (RH). From the IR data, it is shown that d-(AAAAATTTTT)2 and poly(dA).poly(dT) adopt a B-genus conformation in films with high water content. When the relative humidity of the film is decreased, the IR spectra reflect a gradual evolution of the geometry of both d(AAAAATTTTT)2 and poly(dA).poly(dT) into a form intermediate between the B genus and A genus, but the IR spectrum of a pure A genus has not been obtained. In these DNAs at 75% RH, the IR bands of adenosine have the same frequencies as those found in poly(dA-dT) at 75% RH where the local furanose conformation is C3' endo/anti, but the thymidine frequencies do not resemble those of poly(dA-dT) at 75% RH but rather those of poly(dA-dT) at high humidities. It is concluded that both poly(dA).poly(dT) and d(AAAAATTTTT)2 adopt a fully heteronomous duplex geometry in cast films at low humidity. For studies in aqueous solution the Raman effect was employed. As a model for the heteronomous conformation in solution, the duplex poly(rA).poly(dT) was used.(ABSTRACT TRUNCATED AT 250 WORDS)
To investigate whether horses were able to acclimate to conditions of high temperature and humidity, 5 horses of different breeds were trained for 80 min on 15 consecutive days on a treadmill at 30 degrees C and 80%RH. Training consisted of a combination of long duration low-intensity exercise, medium duration medium intensity exercise and short duration high intensity exercise. Between training sessions the horses were maintained at 11+/-3 degrees C and 74+/-2%RH. Before (PRE-ACC) and after acclimation (POST-ACC) the horses undertook a simulated Competition Exercise Test (CET), designed to represent the Speed and Endurance Test of a 3-day event, at 30 degrees C/80%RH. Maximal oxygen uptake (VO2PEAK) was not changed following acclimation (PRE-ACC 141+/-8 ml/min/kg bwt vs. POST-ACC 145+/-9 ml/min/kg bwt [STPD], P>0.05). Following acclimation, 4 of the 5 horses were able to complete a significantly greater amount of Phase D in the CET (PRE-ACC 6.3+/-0.3 min vs. POST-ACC 7.3+/-0.3 min, P<0.05; target time = 8 min). Resting body temperatures (pulmonary artery [TPA], rectal [TREC] and tail-skin [TTSK] temperatures) were all significantly lower following acclimation. During exercise, metabolic heat production (M) and heat dissipation (HD), for the same exercise duration, were both significantly lower following acclimation (P<0.05), although heat storage (HS) was significantly higher (P<0.05). The higher heat storage following acclimation was associated with a lower TTSK for a given TPA and a decreased total fluid loss (% bodyweight, P<0.05). Plasma volume was not changed following acclimation. The relationship of sweating rate (SR) to TPA or TTSK on either the neck or the gluteal region was not significantly altered by acclimation, although the onset of sweating occurred at a lower TPA or TTSK following acclimation (P<0.05). The horses in the present study showed a number of physiological adaptations to a period of 15 days of exposure to high heat and humidity consistent with a humid heat acclimation response. These changes were mostly similar to those reported to occur in man and other species and were consistent with thermal acclimation and an increased thermotolerance, leading to an improved exercise tolerance. It is concluded that a 15 day period of acclimation is beneficial for horses from cooler and or drier climates, that have to compete in hot humid conditions and that this may redress, to some extent, the decrement in exercise tolerance seen in nonacclimated horses and reduce the risk of heat related disorders, such as heat exhaustion.
The effects of humidifier air temperature and flow, and ambient relative humidity (RH(amb)) on RH and air temperature under a radiant warmer (RW) were determined in stable and unstable conditions, using an infant surrogate. Mean supplemented RH under the RW was 36.3% at 14% RH(amb) and 67.6% at 55% RH(amb). Humidifier temperature of 38 degrees C and air flow of 10 LPM produced highest RHs (74.5% and 43.1% in high and low RH(amb), respectively). RH(amb) was highest in summer and lowest in winter in this midwest U.S. hospital, and could be predicted by calendar date (r = 0.58). Humidification equipment capabilities and limitations must be known when using this method to limit evaporative water loss.
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