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At least 19 recordsLinked to original sources
PubMed2000

Targets and reality: a comparison of health care indicators in the U.S. (Pittsburgh Epidemiology of Diabetes Complications Study) and Hungary (DiabCare Hungary).

OBJECTIVE: In the U.S., both primary care and specialist physicians share in the care of type 1 diabetic patients, often in an informal collaboration. In Hungary, however, type 1 diabetic patients are generally managed in special centralized diabetes units. These different treatment settings may lead to different health care practices and outcomes. To determine if this is true, diabetes care indicators and complications were compared across representative study populations from the 2 countries. RESEARCH DESIGN AND METHODS: The Pittsburgh Epidemiology of Diabetes Complications Study (EDC) is a prospective cohort of childhood-onset type 1 diabetic patients. DiabCare Hungary, a multicenter cross-sectional study, was developed for quality control purposes and provides a nationwide data set of diabetic patients. We identified 2 comparable populations (EDC, n = 416; DiabCare, n = 405) in terms of age (> or =14 years) and age at onset (<17 years). RESULTS: EDC patients were less likely to receive diabetes education (P<0.0001), see an ophthalmologist (P<0.0001), be treated by diabetologists (P<0.0001), or perform self-monitoring of blood glucose (P<0.0001). They were more likely to use conservative insulin regimens (i.e., 1-2 injections/day, P<0.0001) and have a higher glycated hemoglobin (P< 0.0001). DiabCare patients more often experienced severe hypoglycemia (P<0.01) and had a lower prevalence of proliferative retinopathy (P<0.0001), legal blindness (P<0.05), and albuminuria (> or =30 mg/day P<0.01). No significant differences in macrovascular complications were seen, although rates were generally low CONCLUSIONS: These data suggest that the 2 populations differ by their diabetes care practices, degree of glycemic control, and microvascular complication status.

Adolescent↗
PubMedDate not supplied

[Public health education and health promotion in Hungary: the role of Canada. The TEMPUS consortium for a New Public Health in Hungary].

The economy of Hungary is undergoing a major transition. The prevalence of behavioural and environmental risk factors is high. The population's health status is among the worst in Europe, and has declined in recent years. The Prussian-style curriculum in the medical universities was rigid and dictated from Budapest and Moscow. The teaching of public health was didactic, there was an emphasis on subjects such as dialectic materialism and hygiene. "Development of Medical Education for a New Public Health in Hungary", a three-year project funded by the European Community's TEMPUS program, is established to develop undergraduate and graduate education. It is a joint program between the five Hungarian medical schools and ten universities in Western countries including Canada. The reformation includes a shift from didactic teaching methods to problem-based learning techniques and greater emphasis on health promotion and population health. Communication within the project is facilitated through an electronic 'list server' based in London, Ontario.

Canada↗
PubMed2002

Comparative studies on Aeromonas strains isolated from Lakes Balaton (Hungary) and Fertó/Neusiedlersee (Hungary).

Ecological and comparative taxonomic investigations were carried out on 49 Aeromonas strains isolated from water samples of two moderately alkaline lakes of Hungary, Lake Balaton and Lake Fertó/Neusiedlersee together with 3 authentic strains of Aeromonas hydrophila. Five phena were created at greater than 92% similarity value using the UPGMA method with the Jaccard coefficient. Strains isolated from Lake Balaton were determined as A. hydrophila, while strains originated from Lake Fertó were identified as A. hydrophila and A. sobria. The Fertó isolates of A. hydrophila grew only at higher salt concentration (5% NaCl). This might be an adaptation to the higher salt contents in the water of Lake Fertó. However, no specific differences were detected in their behaviour against alkaline pH values. The wide range of their degradative enzymes indicate that aeromonads can play an important role in nutrient cycling.

Aeromonas↗
PubMed2005

[Current state and future perspectives of oncology care in Hungary based on epidemiologic data].

The cancer mortality and morbidity data over the period of 1999-2003 in Hungary has been analyzed. The attempts for the harmonization of cancer care's organization between European Cancer Centers and Hungarian Cancer Centers will also be reviewed. Total cancer mortality of Hungary was found to be 33 530 persons in 2003. According to the cancer mortality data of 36 European countries the highest mortality rate were in Hungary for male in 1999. Hungary had the second place in the female cancer mortality in Europe. It has also been found that the Hungarian men had the highest rate tobacco related cancers (lung, oral cancers) in Europe. The trends of the cancer mortality for women is changed during the period 1999-2003. In 1999 breast cancer was the leading cause of cancer's death for women followed by colorectal and lung cancers. The lung cancer rates have been rising in Hungarian women and became the main cause of cancer death in 2002. The unfavorable cancer mortality trends in Hungary might be attributed to the high consumption of tobacco and alcohol, moreover the unsatisfactory care of cancer patients. The cancer mortality in Hungary could be reduced by the improvement of prevention, diagnosis and treatment of cancer patients. The European accreditation of the cancer control activities should be based on the network of Cancer Centers in Hungary. This accreditation of the Hungarian Cancer Centers is indispensable for the high quality of the care of cancer patients.

Accreditation↗
PubMed2005

[Molecular detection and sequence analysis of hepatitis A virus (HAV) in two outbreaks in 2004 in North East Hungary].

INTRODUCTION: Hepatitis A virus (HAV) is the most important cause of acute infectious hepatitis worldwide. In Hungary, the reported number of HAV infections decreasing in the last decades, however, in every year approximately 500-800 new cases occur. In Hungary, particularly in North East region not only sporadic cases but also outbreaks of HAV are happen from time to time. Serology is routinely used laboratory method for diagnosis of HAV infections, although, there was no direct molecular detection and sequence analysis for the circulating HAV strains in Hungary. AIMS: Author's aims were to detection and genetic characterization of hepatitis A virus in outbreaks of hepatitis by molecular methods for reason of molecular epidemiology in Hungary. MATERIALS AND METHODS: Sera samples from symptomatic patients were tested from two acute hepatitis outbreaks in two settlements (Hajdúböszörmény and Kázsmárk) in North East Hungary in 2004 by enzim-immunoassay (EIA) and reverse transcription-polymerase chain reaction (RT-PCR). RESULTS: Sera in 58 (100%) and 4 (28.6%) symptomatic patients were positive in outbreaks of Hajdúböszörmény and Kázsmárk by HAV IgM EIA, however, 4 (57.1%) and 2 (66.6%) HAV IgM positive samples were positive by RT-PCR. By sequence analysis, outbreaks caused by the same hepatitis A virus which belongs to genotype I, subtype IA. These viruses had 98.4% nucleotide identity to IT-SCH-00 virus detected in year 2000 in Italy the closest match in GenBank. CONCLUSIONS: Methods of molecular biology give new opportunity for surveillance of infectious diseases in public health. Firstly characterized hepatitis A viruses in Hungary show that the subtype IA have an important epidemiological role in outbreaks. It is also suggested that genotype IA HAV play a part in sporadic HAV cases in endemic region in Hungary, too.

Adolescent↗
PubMed1999

Regional differences in mortality: a comparison between Austria, Hungary and Switzerland.

BACKGROUND: Important differences in mortality rates exist even between neighbouring countries. This should facilitate the identification of the lifestyle parameters underlying these differences. The mortality rates obtained in Hungary, Austria and Switzerland were compared. METHODS: The mortality rates for all-cause, total cardiovascular, total cancer and stroke mortality were obtained from a special tape from WHO. Nutritional data were obtained from FAO food balance sheets and from dietary surveys. Gompertz and polynomial equations were calculated from the age-specific mortality rates. FINDINGS: Great differences in mortality exist between the three countries. In the period from 1950 until 1995 mortality decreased in Austria and Switzerland, but increased in Hungary. In men, total cancer and total cardiovascular mortality also increased markedly in Hungary during the last 20 years. Hungary has a lower dietary P/S ratio, a higher level of animal/vegetal fat and a lower consumption of fruit than Austria and Switzerland, combined with a high level of salt consumption. The level of cigarette smoking is similar in Hungary and Switzerland. The increase in mortality rate in Hungary is less pronounced in women than in men. INTERPRETATION: The major differences in lifestyle between the three countries concern socio-economic and nutritional patterns. Epidemiological evidence favours nutrition as the most important determinant of the differences in mortality rates between the three countries.

Adult↗
PubMed2000

[Trends of premature mortality from cardiovascular diseases in Hungary and the European Union, 1970-1997].

It is a well known fact that in Hungary--as in the European Countries, in general--the trends of premature mortality are mainly determined by the trends of mortality caused by cardiovascular diseases. The timeliness of our present study on changes in trends of early cardiovascular mortality in the period of 1970-1997 in Hungary in comparison with trends of EU countries is underlined by the upcoming access of Hungary to the European Union. The evaluation is based on WHO data, the relative risk of premature mortality due to different forms of cardiovascular diseases for different sex and age groups of the Hungarian population is expressed as a ratio between standardized mortality rates of Hungarian groups and that of EU-average and of countries specified. Detailed data demonstrate that the risk of early death caused by cardiovascular--especially ischaemic heart and cerebrovascular--diseases, in contrast with EU countries, is significantly increased in Hungary, most significantly in age groups of 35-44 and 45-64 years for both sexes. The authors' results draw the attention to the possible shortcomings of health care systems and the lack of comprehensive health promotion (including prevention) programs in Hungary.

Adolescent↗
PubMed2002

[Epidemiologic surveillance of childhood leukemia in Hungary over the past 21 years (1980-2000)].

INTRODUCTION: Investigation of trends in incidence rates of childhood malignancies, especially leukaemia and thyroid cancers, is essential for the objective assessment of health consequences of the nuclear power plant accident in Ukraine in 1986. AIMS: This paper reports the results of the epidemiological surveillance of childhood leukaemia in Hungary from 1980 to 2000, according to the database of the Hungarian Paediatric Cancer Registry. METHODS: All childhood leukaemia cases diagnosed between the period of 1 January 1980 and 31 December 2000, age of 0-14, throughout Hungary have been recorded. The registration was done by the ten Paediatric Oncology Centres in Hungary. The total number of diagnosed and analysed cases was 1563. RESULTS: The incidence rate of childhood leukaemia showed a gradual, slow but significant increase of 1.2% per year over the observed period of time. There was neither any additional increase in the incidence following the accident, nor an increase in the cumulative incidence among the children born around the date of the accident. The accident did not cause a change regarding the infant leukaemia incidence in Hungary either. Apparent change in the geographical distribution of childhood leukaemia, which could be the result of the accident, was not detectable. CONCLUSION: The authors did not detect any change in the incidence of childhood leukaemia over the past 21 years in Hungary, which can be attributed to the nuclear power plant accident in Ukraine in 1986.

Adolescent↗
PubMed2002

Some aspects of secular changes in Hungary over the twentieth century.

Growth and maturation are considered the most reliable indicators of health status. Their progression rates in turn are strongly influenced by nutrition and socio-economic status, a well-documented relationship. The pattern of the so-called positive secular changes, i.e. the increase in size and earlier maturation, fits the populations' historical model of economic development very well. The historical, political and economic changes occurring in this century in Hungary have had a remarkably strong impact. Until World War I Hungary was an agrarian part of the Austro-Hungarian monarchy, its ethnic composition was most variegated. Both World Wars caused fundamental changes, namely in respect of post-war Hungary they were associated with marked territorial losses and considerable population mobility. In interpreting the developmental differences in the data collected before and after these wars one should take account of the important facts that, in addition to the changes in socio-economic conditions, affected the gene pool of the populations in Hungary. Over the past 100 years profound changes have occurred in the mean body size, growth rate and timing of maturation of the country's population. This paper is a brief analytic summary of the tendencies observed in adult stature, maturation and some socio-economic conditions. It also compares the cohorts of sub-populations as reflected by the reviewed reports. In summarizing the change in adult stature estimated by the data on recruits, soldiers and students of higher education, it could be stated that adult mean stature had become markedly taller in Hungary since the end of the fifties. However, any estimation of the absolute increment and the exact rate is severely biased by the variable character of the samples' representativeness. Similar problems arose in dealing with sexual maturation, because the retrospective and status-quo methods of assessment were found incomparable. Nevertheless, menarche was observed to have shifted to an appreciably younger age lately, a trend that by the end of the 20th century seemed to have reached a more or less stable level.

Anthropology, Physical↗
PubMed2003

[Malaria in Hungary: origin, current state and principles of prevention].

Malaria was an endemic disease in Hungary for many centuries. A country-wide survey of the epidemiologic situation on malaria started in the year of 1927. That was done by the Department of Parasitology of the Royal State Institute of Hygiene (presently: Johan Béla National Center for Epidemiology). The notification of malaria was made compulsory in 1930. Free of charge laboratory examination of the blood of persons suffering from malaria or suspected of an infection have been carried out. Anti-malarial drugs were also distributed free of charge, together with appropriate medical advise given at the anti-malarial sanitary stations. Between 1933 and 1943, the actual number of malaria cases was estimated as high as 10-100,000 per year. The major breakthrough came in 1949 by the organized antimalarial campaign applying DDT for mosquito eradication. The drastic reduction of the vectors resulted in the rapid decline of malaria cases. Since 1956, there have not been reported any indigenous case in Hungary. In 1963, Hungary entered on the Official Register of the WHO to the areas where malaria eradication has been achieved. During the period of 1963-2001, 169 Hungarians acquired the malaria in abroad and 263 foreigners infected in abroad were registered in Hungary. More than half of the cases (230) were caused by Plasmodium falciparum. Further 178 cases were caused by Plasmodium vivax and 24 cases by other Plasmodium species. During that period, 7 fatal cases were reported (Plasmodium falciparum). The expansion of migration (both the increase of the number of foreigners travelling into Hungary and of Hungarians travelling abroad) favours to the appearance of imported cases. Attention is called of all the persons travelling to malaria endemic countries to the importance of malaria prevention by the International Vaccination Stations located in the National Center for Epidemiology and in the Public Health Institutes of 19 counties and of Budapest. The Johan Béla National Center for Epidemiology issued a protocol in 2001, the title of which is: "Antimalarial defence". This helps the information activity of the International Vaccination Stations. To prevent malaria infections, systemic mosquito eradication is organized and supervised by the Office of the Chief Medical Officer at the touristically important areas in the summer season.

History, 20th Century↗
PubMed2003

[Establishment and preliminary evaluation of the General Practitioners' Morbidity Sentinel Stations Program in Hungary. Prevalence of hypertension, diabetes mellitus and liver cirrhosis].

STUDY OBJECTIVE: To develop, introduce and test a methodology, which provides valid data about the prevalence and incidence of chronic, non-communicable diseases of great public health importance. DESIGN: The School of Public Health, University of Debrecen, Hungary and the National Public Health and Medical Officer Service the first time launched a morbidity sentinel stations network of general practitioners in four counties in Hungary in May 1998. Within the framework of this program the participating general practitioners reported the prevalence data of cardiovascular diseases, diabetes mellitus, liver cirrhosis, and major malignant diseases at the beginning, and from than on continuously report the incidence of these diseases. The authors built quality assurance into the program at different levels in order to ensure high quality data. PATIENTS: The study population consists of people belonging to the participating general practitioners' practices at any time, selected in a way to represent the eastern and western part of the country as well as the participating practices in the counties (Gyór-Moson-Sopron, Hajdú-Bihar, Szabolcs-Szatmár-Bereg, Zala) would give a geographically and according to settlement size representative sample of general practitioners in those counties. Eighty general practitioners were approached in the four counties by the county offices and overall 73 of them, 1.4% of the total practices in Hungary (5212), agreed to participate in the study, therefore information can be collected on 1.37% of the Hungarian population's (138,088 people) morbidity status. MAIN RESULTS: The population of practices participating in the program gives a representative sample of the counties population by age and sex. The prevalence of hypertension, diabetes mellitus and liver cirrhosis is high in all the counties involved. In most of the selected diseases the authors have found differences in the prevalence between the eastern and western part of Hungary with higher values in the western counties. The differences were most apparent in the older age groups in both sexes. CONCLUSIONS: The development and sustainability of primary care based, sentinel stations type, euroconform morbidity data collection system is undoubtedly justified in Hungary. The collected and thoroughly analysed data provide not only a valid and comprehensive basis to describe some aspects of the health status of the Hungarian population but also gives an opportunity to continuously monitor the changes in morbidity of the selected diseases. Thus, the program serves an important basis for health care capacity building, priority setting and the evaluation of the effectiveness of public health interventions.

Adolescent↗
PubMed1995

Group A rotavirus G type prevalence in two regions of Hungary.

Rotaviruses are a major cause of gastroenteritis in children world-wide. Rotaviruses are antigenically complex, with multiple serotypes (G types). The first longitudinal study of group A rotavirus serotype (G type) distribution in Hungary is reported. Neutralizing monoclonal antibodies specific for G1, G2, G3, and G4 were used in an enzyme immunoassay to determine the antigenic variation of group A rotaviruses in two collections of stool specimens assembled from 1984-1992 in Baranya County, southwest Hungary, and from 1988-1992 at the Central Hospital for Infectious Diseases in Budapest. Ninety-two percent of the 1215 virus-positive samples were typed as follows: G1 (81%), G2 (4%), G3 (1%), G4 (5%), or mixed type (1%). G1 was the predominant type during the entire study period with the exception of the 1988/1989 rotavirus season in Baranya County when G4 predominated. Among G1 strains, different electropherotypes were detected with a shift of the predominant G1 electropherotype(s) each 2 to 3 years. G typing from two longitudinal collections established regional differences within Hungary in the prevalence of rotavirus antigenic types among children with rotavirus-associated diarrhea. These are the first longitudinal rotavirus typing results for Hungary and Central Europe.

Antibodies, Monoclonal↗
PubMed1994

Multicenter study in Hungary with a 30 micrograms ethinylestradiol- and 150 micrograms desogestrel-containing monophasic oral contraceptive.

Among the countries in Central and Eastern Europe, Hungary has a high oral contraceptive prevalence rate. Until recently, however, Hungarian women have not had access to combined oral contraceptives with new, third-generation progestogens. Marvelon (30 micrograms ethinylestradiol and 150 micrograms desogestrel) was first introduced in 1981 in Western Europe and has, in a number of different studies, proven an effective and well-tolerated oral contraceptive with no effect on blood pressure and a favorable lipid profile. Marvelon was introduced in Hungary in October 1991. Prior to its introduction, a multicenter study was undertaken in Hungary with Marvelon to confirm the clinical results of studies from other countries. The present study confirmed Marvelon to be an effective, well-tolerated combined oral contraceptive with no relevant effect on blood pressure. Remarkable improvements were noted, especially with regard to side-effects, in switchers from other oral contraceptives. It is concluded that Marvelon is a valuable extension of the range of contraceptive methods available in Hungary.

Adolescent↗
PubMed2005

Childhood leukaemia incidence in Hungary, 1973-2002. Interpolation model for analysing the possible effects of the Chernobyl accident.

The incidence of childhood leukaemia in Hungary has yet to be reported, although data are available since the early 70s. The Hungarian data therefore cover the time before and after the Chernobyl nuclear accident (1986). The aim of this study was to assess the effects of the Chernobyl accident on childhood leukaemia incidence in Hungary. A population-based study was carried out using data of the National Paediatric Cancer Registry of Hungary from 1973 to 2002. The total number of cases was 2204. To test the effect of the Chernobyl accident the authors applied a new approach called 'Hypothesized Impact Period Interpolation'-model, which takes into account the increasing trend of childhood leukaemia incidence and the hypothesized exposure and latency times. The incidence of leukaemia in the age group 0-14 varied between 33.2 and 39.4 per million person-years along the observed 30 year period, and the incidence of childhood leukaemia showed a moderate increase of 0.71% annually (p = 0.0105). In the period of the hypothesized impact of the Chernobyl accident the incidence rate was elevated by 2.5% (95% CI: -8.1%; +14.3%), but this change was not statistically significant (p = 0.663). The age standardised incidence, the age distribution, the gender ratio, and the magnitude of increasing trend of childhood leukaemia incidence in Hungary were similar to other European countries. Applying the presented interpolation method the authors did not find a statistically significant increase in the leukaemia incidence in the period of the hypothesized impact of the Chernobyl accident.

Adolescent↗
PubMed1996

Compulsory testing for HIV in Hungary.

Compulsory testing for the human immunodeficiency virus (HIV) has been a cornerstone of Hungary's AIDS prevention and care programme since 1988. This strategy is based on a two-fold public health rationale. Firstly, informing as many HIV positive people as possible of their serostatus is important for HIV prevention because infected people have a crucial role to play in preventing the further spread of the virus. Secondly, the earlier an HIV diagnosis can be provided the greater the opportunity for delaying the onset of symptoms and for maintaining as high a quality of life as possible for the affected individual. For these reasons, and because compulsory testing appears to be widely accepted within Hungary as part of a comprehensive social welfare system which places equal emphasis on citizens' rights and responsibilities, the country's public health establishment has continued to resist pressure from international agencies and other external bodies which have urged Hungary to abandon compulsory testing in favour of voluntary testing based on individual informed consent. Any changes to Hungary's HIV testing programme which occur in the coming years are more likely to be a response to the country's changing epidemiological, social and economic conditions rather than to pressure from outside.

Community Health Services↗